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The map label for this gene is nagB

Identifier: 45658010

GI number: 45658010

Start: 2610410

End: 2611069

Strand: Reverse

Name: nagB

Synonym: LIC12161

Alternate gene names: 45658010

Gene position: 2611069-2610410 (Counterclockwise)

Preceding gene: 45658011

Following gene: 45658009

Centisome position: 61.05

GC content: 32.58

Gene sequence:

>660_bases
GTGCATATTATCGAATTTTCTAACGAGCGAGATTTTCTAGATCATTGTTTGGATAGAATTAAAGAAATTTCTGCAAATAA
AATTCAAACGAAGAGTTCTTTTCATATAGTTCTTACGGGTGGAGATACTGCAAAGTTATTATACTCCGAATTAAAACATT
TGAAAACAGATTGGTCAAAGTGGTTTTTTTATTTCGGAGATGAGAGATGTGTTCCGAAAGATCATATTGATTCTAATTGG
TTGATGGCTGAAAGAGTTTTATTTAAATTTATACCTGTGAATGAAAGACAAATTTTTAAGATACCAGGCCATCTTGGACC
TCAGCGAGGGGCTTTAGAATATTCAGAATCTATTAAATCTATTTCCTCATTTGATTTAGTTCTTCTGGGTTTAGGAGAGG
ATGGTCATATCGCAAGTCTTTTTCCGGGGATGGATTTGACAAATGAAGAAGACGTAATTGCTATTTACGATTCTCCGAAA
TTACCAAAAGAAAGAGTTAGTTTATCTTTGAGGAAAATCAATTTATCGGATTTTATTTTAATCATAGCAAAAGGAAGAAA
GAAAGAAGAAATCATCGAAAGAATTAAGATGGATGAGGCTTTACCAGTTACGTCTCTTTCTTCCAGAAAATCGGTGGAAC
TCTGTTATTTTTACAATTAA

Upstream 100 bases:

>100_bases
TCGACTTAATAACAAAAAGTCAAATCCCTTTTTCGCTCGAAATGGGTGTAAAATGATAATTAGAAAAGAAGAATATTCTT
CTAAATTTAAAGGGTAAGCT

Downstream 100 bases:

>100_bases
ATTCCTAACTTGCACAAATAAACAAACTAAATCGCAGAAAAGGATTTTTAAATGAGAGTGATCATTAAAAGTTGTATCAC
CAAAACTATTTCTTTTATTG

Product: 6-phosphogluconolactonase/glucosamine-6- phosphate isomerase/deaminase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MHIIEFSNERDFLDHCLDRIKEISANKIQTKSSFHIVLTGGDTAKLLYSELKHLKTDWSKWFFYFGDERCVPKDHIDSNW
LMAERVLFKFIPVNERQIFKIPGHLGPQRGALEYSESIKSISSFDLVLLGLGEDGHIASLFPGMDLTNEEDVIAIYDSPK
LPKERVSLSLRKINLSDFILIIAKGRKKEEIIERIKMDEALPVTSLSSRKSVELCYFYN

Sequences:

>Translated_219_residues
MHIIEFSNERDFLDHCLDRIKEISANKIQTKSSFHIVLTGGDTAKLLYSELKHLKTDWSKWFFYFGDERCVPKDHIDSNW
LMAERVLFKFIPVNERQIFKIPGHLGPQRGALEYSESIKSISSFDLVLLGLGEDGHIASLFPGMDLTNEEDVIAIYDSPK
LPKERVSLSLRKINLSDFILIIAKGRKKEEIIERIKMDEALPVTSLSSRKSVELCYFYN
>Mature_219_residues
MHIIEFSNERDFLDHCLDRIKEISANKIQTKSSFHIVLTGGDTAKLLYSELKHLKTDWSKWFFYFGDERCVPKDHIDSNW
LMAERVLFKFIPVNERQIFKIPGHLGPQRGALEYSESIKSISSFDLVLLGLGEDGHIASLFPGMDLTNEEDVIAIYDSPK
LPKERVSLSLRKINLSDFILIIAKGRKKEEIIERIKMDEALPVTSLSSRKSVELCYFYN

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912586, Length=206, Percent_Identity=32.0388349514563, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI52145310, Length=187, Percent_Identity=33.6898395721925, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI115533058, Length=184, Percent_Identity=28.2608695652174, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533060, Length=184, Percent_Identity=28.2608695652174, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321957, Length=213, Percent_Identity=31.4553990610329, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324362, Length=207, Percent_Identity=31.4009661835749, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321687, Length=221, Percent_Identity=27.6018099547511, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319918, Length=209, Percent_Identity=30.1435406698565, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641119, Length=203, Percent_Identity=30.0492610837438, Blast_Score=98, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25269; Mature: 25269

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIIEFSNERDFLDHCLDRIKEISANKIQTKSSFHIVLTGGDTAKLLYSELKHLKTDWSK
CEEEEECCCCHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCHHHHHHHHHHHHHCCHHE
WFFYFGDERCVPKDHIDSNWLMAERVLFKFIPVNERQIFKIPGHLGPQRGALEYSESIKS
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHH
ISSFDLVLLGLGEDGHIASLFPGMDLTNEEDVIAIYDSPKLPKERVSLSLRKINLSDFIL
HCCCEEEEEEECCCCCEEEECCCCCCCCCCCEEEEECCCCCCHHHHEEEEEEECCCEEEE
IIAKGRKKEEIIERIKMDEALPVTSLSSRKSVELCYFYN
EEECCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MHIIEFSNERDFLDHCLDRIKEISANKIQTKSSFHIVLTGGDTAKLLYSELKHLKTDWSK
CEEEEECCCCHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCHHHHHHHHHHHHHCCHHE
WFFYFGDERCVPKDHIDSNWLMAERVLFKFIPVNERQIFKIPGHLGPQRGALEYSESIKS
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHH
ISSFDLVLLGLGEDGHIASLFPGMDLTNEEDVIAIYDSPKLPKERVSLSLRKINLSDFIL
HCCCEEEEEEECCCCCEEEECCCCCCCCCCCEEEEECCCCCCHHHHEEEEEEECCCEEEE
IIAKGRKKEEIIERIKMDEALPVTSLSSRKSVELCYFYN
EEECCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]