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The map label for this gene is sglT [H]

Identifier: 45657653

GI number: 45657653

Start: 2177920

End: 2179542

Strand: Direct

Name: sglT [H]

Synonym: LIC11787

Alternate gene names: 45657653

Gene position: 2177920-2179542 (Clockwise)

Preceding gene: 45657650

Following gene: 45657659

Centisome position: 50.92

GC content: 34.2

Gene sequence:

>1623_bases
GTGAACACAATCAAACAAGAAAACTTGTGGGAATTCCAATTTCATTTTTGCGAAAAAAATCCGATGTGTTGCTTGAGTTC
TTATAAAGAACCTCAATTCAAAGAAAAAGAGTTTTCCGGGTCTTTTGAAAATGAATTCTGCCTGATTATGCACTTTTCAT
TTTTAGATCTAACCGTTTTACTTTTCTATGTTGGTTTGGTTCTTTTTTCGGGATGGTTCACTTCTAGAAAAAAAGATAAG
GATTCCGCTTCTTACTTTCTTGCAGGAAAAGAAATTTCTTGGATTGCTTTGAGCTTTTCAATCGTTGCCACAGAAACGTC
TACTCTTACTTTTTTGAGCATTCCTGGACTTAGTTATTCAAGTAATCTTACCTTTCTTAGCCTCGGTTTGGGTTTTGTTT
TAGGAAGAATTATCGTAGCCAAACTTTTTATTCCTATGTATTACAAATCCGGTTTTATTTCCGTTTATGAATGGGTAGGA
AACCACTATGGAAAAATTTCTCAAAAGACGGTCACATTTTTATTCAAACTCACTCGCATTTTAGGAGACGGAGTGAGAAT
GTATGCATCCGCTATTCCGGTTGCGATTTTACTTGAAGTTTTCTTAAAACAGTTTTCTTTATTAAAAACCACAAATCTAC
ACATAGAAATTTTAAGTCTTCTACTCATTTCCGGAATCACAATTCTTTACACAGTTCAGGGAGGATTTCGTTCCGTGGTC
TGGGTAGATTCGATTCAATTTTTAATCTACGTCGCAGGAGGAATTTTTGCGCTTTTCTATTTAGGTTCTATACTTCTTAA
AAATGGATTCGACGCTTCTTATCTGATCGAAAATGCAAATCAAACAAATAAGTTTCAAATTTTTGAATGGACAGATTTTT
CATCCGCTTATTTTTTTCCCACTGCTATTTTAGGAGGAATTCTTTTAACCTTAGGAACCCACGGAGTAGATCAGATGTTT
GTTCAAAGAATACTCGCGTGTAGATCAGAATCGGACGCCCAAAAGGCGATGATTTCTTCTGGAATTTTTGTATTTTTTCA
GTTCGTATTATTTTTAAGCATTGGAGTTTTATTATATTTTTATTATAAAGATCCCTCTATTCCTAAAGATAAGGTTTTTT
CCAAATTTATTTTAGAGGAAGTACCTTCGCCAATCACAGGTTTTTTATTAGCCGCTATTTTGGCTTCGGCTATGTCTACA
TTATCTAGTTCTATCAATTCTCTTTCTTTGACTACTAAAGTAGATTTAAAAATAGAACAATTCGGTTCTGGTACTTTAAG
CTTATTCTGGGGGATGATTCTTCTCTTAAGTTCCCTACTTCCTCTATTTTTAACAACCGGAAAAAAGGGTCTTGTAGAAT
TAGGATTATCTATCTCTTCTTATACTGTTGGTCCAATCATTTCAATTTTTCTAAGCGGAAGAATACAAAGTTTTTATTAT
ATGCAAAAATTAAAGGATTCTTTTGCGTCTTTGGCGATCGGACTAACTCCAATTTTAACATTAATTTTCGGTAAATGGAC
CGGTTCCAGTTTTACTCTTCTGGTTCCATTCGGGATCGGAACCTGCTGGTTGCTCGGATTTAGTTTACTACAAATTCAGA
ATCGTCTAACTTCTCAAAAATAG

Upstream 100 bases:

>100_bases
CCAGAATTTCTTTCCGAATGAAAACGTCATTTTATTTTCCGCTTTCAAAATCAGGATTTTCATACACAACTACAAATTCT
TAAATCAGAAACTGCAACTC

Downstream 100 bases:

>100_bases
ATTCCAAAATTTTTTTAAACTCAAATGACTTTGTAAAATGAATATAATGGTCACCGCCAGGAATTAAGTAAAATTTAGAA
TTTGGAAAAAAATTTCGAGC

Product: sodium:solute symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MNTIKQENLWEFQFHFCEKNPMCCLSSYKEPQFKEKEFSGSFENEFCLIMHFSFLDLTVLLFYVGLVLFSGWFTSRKKDK
DSASYFLAGKEISWIALSFSIVATETSTLTFLSIPGLSYSSNLTFLSLGLGFVLGRIIVAKLFIPMYYKSGFISVYEWVG
NHYGKISQKTVTFLFKLTRILGDGVRMYASAIPVAILLEVFLKQFSLLKTTNLHIEILSLLLISGITILYTVQGGFRSVV
WVDSIQFLIYVAGGIFALFYLGSILLKNGFDASYLIENANQTNKFQIFEWTDFSSAYFFPTAILGGILLTLGTHGVDQMF
VQRILACRSESDAQKAMISSGIFVFFQFVLFLSIGVLLYFYYKDPSIPKDKVFSKFILEEVPSPITGFLLAAILASAMST
LSSSINSLSLTTKVDLKIEQFGSGTLSLFWGMILLLSSLLPLFLTTGKKGLVELGLSISSYTVGPIISIFLSGRIQSFYY
MQKLKDSFASLAIGLTPILTLIFGKWTGSSFTLLVPFGIGTCWLLGFSLLQIQNRLTSQK

Sequences:

>Translated_540_residues
MNTIKQENLWEFQFHFCEKNPMCCLSSYKEPQFKEKEFSGSFENEFCLIMHFSFLDLTVLLFYVGLVLFSGWFTSRKKDK
DSASYFLAGKEISWIALSFSIVATETSTLTFLSIPGLSYSSNLTFLSLGLGFVLGRIIVAKLFIPMYYKSGFISVYEWVG
NHYGKISQKTVTFLFKLTRILGDGVRMYASAIPVAILLEVFLKQFSLLKTTNLHIEILSLLLISGITILYTVQGGFRSVV
WVDSIQFLIYVAGGIFALFYLGSILLKNGFDASYLIENANQTNKFQIFEWTDFSSAYFFPTAILGGILLTLGTHGVDQMF
VQRILACRSESDAQKAMISSGIFVFFQFVLFLSIGVLLYFYYKDPSIPKDKVFSKFILEEVPSPITGFLLAAILASAMST
LSSSINSLSLTTKVDLKIEQFGSGTLSLFWGMILLLSSLLPLFLTTGKKGLVELGLSISSYTVGPIISIFLSGRIQSFYY
MQKLKDSFASLAIGLTPILTLIFGKWTGSSFTLLVPFGIGTCWLLGFSLLQIQNRLTSQK
>Mature_540_residues
MNTIKQENLWEFQFHFCEKNPMCCLSSYKEPQFKEKEFSGSFENEFCLIMHFSFLDLTVLLFYVGLVLFSGWFTSRKKDK
DSASYFLAGKEISWIALSFSIVATETSTLTFLSIPGLSYSSNLTFLSLGLGFVLGRIIVAKLFIPMYYKSGFISVYEWVG
NHYGKISQKTVTFLFKLTRILGDGVRMYASAIPVAILLEVFLKQFSLLKTTNLHIEILSLLLISGITILYTVQGGFRSVV
WVDSIQFLIYVAGGIFALFYLGSILLKNGFDASYLIENANQTNKFQIFEWTDFSSAYFFPTAILGGILLTLGTHGVDQMF
VQRILACRSESDAQKAMISSGIFVFFQFVLFLSIGVLLYFYYKDPSIPKDKVFSKFILEEVPSPITGFLLAAILASAMST
LSSSINSLSLTTKVDLKIEQFGSGTLSLFWGMILLLSSLLPLFLTTGKKGLVELGLSISSYTVGPIISIFLSGRIQSFYY
MQKLKDSFASLAIGLTPILTLIFGKWTGSSFTLLVPFGIGTCWLLGFSLLQIQNRLTSQK

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI4507035, Length=370, Percent_Identity=27.2972972972973, Blast_Score=126, Evalue=6e-29,
Organism=Homo sapiens, GI157671931, Length=444, Percent_Identity=24.0990990990991, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI17941285, Length=396, Percent_Identity=24.2424242424242, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI167466278, Length=418, Percent_Identity=24.4019138755981, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI256985183, Length=404, Percent_Identity=26.4851485148515, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI14140236, Length=462, Percent_Identity=23.8095238095238, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI4507031, Length=471, Percent_Identity=22.9299363057325, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI110835708, Length=407, Percent_Identity=21.1302211302211, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI206597483, Length=453, Percent_Identity=22.2958057395143, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI109659836, Length=410, Percent_Identity=23.9024390243902, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI109659839, Length=514, Percent_Identity=22.9571984435798, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1790113, Length=346, Percent_Identity=25.4335260115607, Blast_Score=89, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI115533094, Length=452, Percent_Identity=25, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI115533096, Length=296, Percent_Identity=28.0405405405405, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24651739, Length=450, Percent_Identity=24.4444444444444, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28573698, Length=351, Percent_Identity=25.6410256410256, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281362918, Length=322, Percent_Identity=24.5341614906832, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24645928, Length=373, Percent_Identity=23.0563002680965, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24651741, Length=348, Percent_Identity=25.5747126436782, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221459584, Length=438, Percent_Identity=23.2876712328767, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640370, Length=412, Percent_Identity=24.0291262135922, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28574994, Length=405, Percent_Identity=24.4444444444444, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24641117, Length=425, Percent_Identity=24, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221459588, Length=430, Percent_Identity=23.2558139534884, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24650192, Length=426, Percent_Identity=21.5962441314554, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19920916, Length=362, Percent_Identity=24.8618784530387, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281362054, Length=476, Percent_Identity=21.6386554621849, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362052, Length=476, Percent_Identity=21.6386554621849, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362050, Length=476, Percent_Identity=21.6386554621849, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648056, Length=476, Percent_Identity=21.6386554621849, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356827, Length=476, Percent_Identity=21.6386554621849, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221379702, Length=426, Percent_Identity=22.5352112676056, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 60407; Mature: 60407

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIKQENLWEFQFHFCEKNPMCCLSSYKEPQFKEKEFSGSFENEFCLIMHFSFLDLTVL
CCCCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCHHCCCCCCCCEEEEEEHHHHHHHHH
LFYVGLVLFSGWFTSRKKDKDSASYFLAGKEISWIALSFSIVATETSTLTFLSIPGLSYS
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEEEEEEEEECCCEEEEEEECCCCCC
SNLTFLSLGLGFVLGRIIVAKLFIPMYYKSGFISVYEWVGNHYGKISQKTVTFLFKLTRI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LGDGVRMYASAIPVAILLEVFLKQFSLLKTTNLHIEILSLLLISGITILYTVQGGFRSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCEEEH
WVDSIQFLIYVAGGIFALFYLGSILLKNGFDASYLIENANQTNKFQIFEWTDFSSAYFFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCEEEEEECCCCCCHHHH
TAILGGILLTLGTHGVDQMFVQRILACRSESDAQKAMISSGIFVFFQFVLFLSIGVLLYF
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
YYKDPSIPKDKVFSKFILEEVPSPITGFLLAAILASAMSTLSSSINSLSLTTKVDLKIEQ
EECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEC
FGSGTLSLFWGMILLLSSLLPLFLTTGKKGLVELGLSISSYTVGPIISIFLSGRIQSFYY
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MQKLKDSFASLAIGLTPILTLIFGKWTGSSFTLLVPFGIGTCWLLGFSLLQIQNRLTSQK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTIKQENLWEFQFHFCEKNPMCCLSSYKEPQFKEKEFSGSFENEFCLIMHFSFLDLTVL
CCCCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCHHCCCCCCCCEEEEEEHHHHHHHHH
LFYVGLVLFSGWFTSRKKDKDSASYFLAGKEISWIALSFSIVATETSTLTFLSIPGLSYS
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEEEEEEEEECCCEEEEEEECCCCCC
SNLTFLSLGLGFVLGRIIVAKLFIPMYYKSGFISVYEWVGNHYGKISQKTVTFLFKLTRI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LGDGVRMYASAIPVAILLEVFLKQFSLLKTTNLHIEILSLLLISGITILYTVQGGFRSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCEEEH
WVDSIQFLIYVAGGIFALFYLGSILLKNGFDASYLIENANQTNKFQIFEWTDFSSAYFFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCEEEEEECCCCCCHHHH
TAILGGILLTLGTHGVDQMFVQRILACRSESDAQKAMISSGIFVFFQFVLFLSIGVLLYF
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
YYKDPSIPKDKVFSKFILEEVPSPITGFLLAAILASAMSTLSSSINSLSLTTKVDLKIEQ
EECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEC
FGSGTLSLFWGMILLLSSLLPLFLTTGKKGLVELGLSISSYTVGPIISIFLSGRIQSFYY
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MQKLKDSFASLAIGLTPILTLIFGKWTGSSFTLLVPFGIGTCWLLGFSLLQIQNRLTSQK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]