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The map label for this gene is 45657594

Identifier: 45657594

GI number: 45657594

Start: 2102702

End: 2103262

Strand: Reverse

Name: 45657594

Synonym: LIC11728

Alternate gene names: NA

Gene position: 2103262-2102702 (Counterclockwise)

Preceding gene: 45657602

Following gene: 45657591

Centisome position: 49.17

GC content: 36.19

Gene sequence:

>561_bases
GTGATTACATTCAATTTAAACATTAAGCAAGACTTTTTAACTCCAAATCCACACAGTAGGCCTGGAACAAAAATAAAAGA
AGTAAAGGGAATCGTATTACATTGGACAGCTTCACCTAAAGCAACCGCCCAAAACATTCGAGATTATTTTGAAAGCCTAA
AAGCGCCTGATGGTCGATTTGCAAGTGCACATTATGCAGTAGGGCTCGTAGGAGAAATTGTACAATGTATTCCTTTAGAT
GAAATAGCTTATCATTGCGGGAGTAAAACATATACTCCTGAAAAAGAAAAAATTTTAGGACCAGATAGCCCTAATTTTTA
TACCATTGGAATTGAACAATGTGTTCAAGATAGGATCGGAAAATTTACAAAAAAAACCTTAGACAGCGCGGCGAAACTTA
CGGCCCAATTATGCTCTCAATACAATTTAGGAATAGATGACCTATGGACACATCAAGGAATTGTAGGTTGGAAAGATTGT
CCCCGTTGGTATAATACTCATCCCGAAGACTGGATTCGTTTTAAAAAAAGGGTAGGAGATTTATTAAAAAAACCAAATTA
G

Upstream 100 bases:

>100_bases
TACAAATAAATTCAATATCAATTTTTTATATAAAAATTTATCTATATTTAGAATATTATTTATTTTAAATATAGATAAAA
TTTAAATAGGAAAATGCCTA

Downstream 100 bases:

>100_bases
AGTTCAAAAGATAATTTTTGTAAATTTTTTCATTACTGATCTCTATAAAATTGAGAACCTAAATGTCTATCATAAAGTGC
CGTTTCATATAACAATACGA

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: Autolysin; Cell wall hydrolase; ORFL3 [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MITFNLNIKQDFLTPNPHSRPGTKIKEVKGIVLHWTASPKATAQNIRDYFESLKAPDGRFASAHYAVGLVGEIVQCIPLD
EIAYHCGSKTYTPEKEKILGPDSPNFYTIGIEQCVQDRIGKFTKKTLDSAAKLTAQLCSQYNLGIDDLWTHQGIVGWKDC
PRWYNTHPEDWIRFKKRVGDLLKKPN

Sequences:

>Translated_186_residues
MITFNLNIKQDFLTPNPHSRPGTKIKEVKGIVLHWTASPKATAQNIRDYFESLKAPDGRFASAHYAVGLVGEIVQCIPLD
EIAYHCGSKTYTPEKEKILGPDSPNFYTIGIEQCVQDRIGKFTKKTLDSAAKLTAQLCSQYNLGIDDLWTHQGIVGWKDC
PRWYNTHPEDWIRFKKRVGDLLKKPN
>Mature_186_residues
MITFNLNIKQDFLTPNPHSRPGTKIKEVKGIVLHWTASPKATAQNIRDYFESLKAPDGRFASAHYAVGLVGEIVQCIPLD
EIAYHCGSKTYTPEKEKILGPDSPNFYTIGIEQCVQDRIGKFTKKTLDSAAKLTAQLCSQYNLGIDDLWTHQGIVGWKDC
PRWYNTHPEDWIRFKKRVGDLLKKPN

Specific function: Unknown

COG id: COG5632

COG function: function code M; N-acetylmuramoyl-L-alanine amidase

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002502
- InterPro:   IPR002477 [H]

Pfam domain/function: PF01510 Amidase_2; PF01471 PG_binding_1 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 21118; Mature: 21118

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITFNLNIKQDFLTPNPHSRPGTKIKEVKGIVLHWTASPKATAQNIRDYFESLKAPDGRF
CEEEEECCHHHCCCCCCCCCCCCHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCC
ASAHYAVGLVGEIVQCIPLDEIAYHCGSKTYTPEKEKILGPDSPNFYTIGIEQCVQDRIG
CHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHCCCCCCCCCEEEECHHHHHHHHHH
KFTKKTLDSAAKLTAQLCSQYNLGIDDLWTHQGIVGWKDCPRWYNTHPEDWIRFKKRVGD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHHH
LLKKPN
HHCCCC
>Mature Secondary Structure
MITFNLNIKQDFLTPNPHSRPGTKIKEVKGIVLHWTASPKATAQNIRDYFESLKAPDGRF
CEEEEECCHHHCCCCCCCCCCCCHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCC
ASAHYAVGLVGEIVQCIPLDEIAYHCGSKTYTPEKEKILGPDSPNFYTIGIEQCVQDRIG
CHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHCCCCCCCCCEEEECHHHHHHHHHH
KFTKKTLDSAAKLTAQLCSQYNLGIDDLWTHQGIVGWKDCPRWYNTHPEDWIRFKKRVGD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHHH
LLKKPN
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2033382 [H]