| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
Click here to switch to the map view.
The map label for this gene is cheA [H]
Identifier: 45657397
GI number: 45657397
Start: 1884554
End: 1886695
Strand: Reverse
Name: cheA [H]
Synonym: LIC11524
Alternate gene names: 45657397
Gene position: 1886695-1884554 (Counterclockwise)
Preceding gene: 45657398
Following gene: 45657396
Centisome position: 44.11
GC content: 34.97
Gene sequence:
>2142_bases ATGGATCTTTCAGAAGTTAGAGACACGTTTATATCTGAATCAGAAGAACTACTTTCTTCTATGGAATCTAATCTTTTAAT TTTGGAAAAAGATTCTAAAAACAACGAAGGGATTCATTCCGTATTTCGTGCAATCCATACGATCAAAGGAACTTCGGGAA TGTTCGGTTACGAACCCATCGAAAAATTTACTCACGAAGTAGAATCTTTTTTAGATAGAATTCGTTCCAATAAACAAAGT CTTACAAAAGAAGGAATTGAATTTTTATTTTTAGCCTGTGATCATATTCGTAATCTTTTGCAAGGTGTTGGAGAAACTTT GATTGTAGATTCTCAAACCTCGCGCAATCAAGTTAATTTACTTTCTTTAGCTAAAAAACTGACCTTAGACGATACTTCTA ATCCACAAAAGGACGAAGCGCTAGTACAAAACCAATCTACATCTTCAAATCTACTTGACTTTCATTCTAGTTCTACTTTT TGGCAAATTACATTGATTCCTAATATTCATCTTTTTGAATCTGGACTGGATCCTTCTACGTTTATCAAATATCTATCTCA ATCCGGAAAGGTAAAACATATTTTTGTTTATCCAGAATCAATCCCCAATTGGTCTGAATTCAATCCAGAACATTCCCATT TGGGTTTTGAAATTTCATATGAATCCCCTTCCAAAGGTGAAGAGATCTATTCTACATTCCAATTTTTGAAAGAAGGAAGT TATCTTAAAATTCTTTCTCCAGGATGTAGCCTGAATCTTTTTATGGAAAACTGCAATGATTTTCCCTTAGGAAAAAAAGC ATATTTAAATGCTTTAGAAATTCAAAAAGTTCTCACACCAGAAGAGATTCAAAAACTATCATATACTTCTGAAAACCTAA ATGTTCTATCTACTACTCAAACGGAACAAACTACTACTTCCATCGAAAACCAAAAAGAATCCGATTCTATCAAAATACAA ACAAAAACGCTGAGAGTAGATTCTTCCAAAATAGACACGTTAATCGCACTTGTTGGTGAGTTGATTACACAAGAAGCAAA TCTAAGTCGAAAAATATCAGATTCTGAAAACCTACAATTGATCGAAAGTTCAGAGTCTCTTTACAGACTCGTAACAGAAA TTCGTGAATTTGCTCTCAGTCTTAGAATGATTCCTATCTCAGATTTATTCGAGAAGTATAAACGTGTAGTACGAGATCTT TCTAAAGAACTGAATAAACAAGTAGAATTAGAAATTATTGGCGGCGAAACAGAATTGGATCGTTCCGTGATAGAAAAGAT CTCGGATCCGATCGTTCACATTCTGAGAAACGCTTTAGATCACGGTATAGAAACATCAGAAGAAAGAATTAAAAAAGGAA AACACGCAACCGGACAATTGAAAATACAAGCAAGTCATGGTACTGGTAGTATTCTAATCGAAATCAAAGATGATGGCAAA GGCCTAGACTGTGATAAAATTTTAGAAAAAGCAATTTCAAAGGGATTAATTACACGAGATCAAAACTTATCCGAATCTGA AATTTATTCTCTGATCTTTCAACCCGGTTTTTCTACTGCGGACCAAGTCACCAATCTTTCCGGAAGAGGTGTAGGAATGG ACGTTGTCTTAAGAAACATCGAATCTCTCCGTGGAACCGTTCAGATTCAAACTCTAAAAGATCAAGGAAGTTCATTTCAA ATTCGTCTACCTCTGACTCTCGCAATCATTGATGGTTTTTTAGTAAAAGCGTCCAGTCTTTACTTTATCGTACCAATGCA GATGGTTCGTGAAACCGTAGAATCTAAGGTAATCTTAAACGGCTCGTCTTCTGGCACAATGAATCTTCGAGGAGAACTTC TTCCTGTGCTTCATCTTTCCGAGTTTCTTTGTTTAGAATCCACTTATTTTGAAAAAGAGAATATTCTAGTTTTAGAATAT GAGGACAAATCTTTCGGAATTATAGTTAACGACCTTCACGGAGAAGTTCAATCCGTAATCCGTCCTATGGCAGAAATCTT TAAGAACATCAAATGTTTCAGTGGTACTTCAATTTTAGGAAGCGGAGAAATCGCTTTTATACTAGACGTTCCCGGTTTAT ACAATTCCATCCGGGATCAAGAACTAAATAAAAACAAGGATCTGGTGACTAAAACGGGTTAA
Upstream 100 bases:
>100_bases TTTAAGTCTGATCGATCTCTATAACCTCTCCGATTTTTTTAGAGATTCAATCCGGCCTTCCAAAGAAGAAGTTCCAGAGA AAGAGGTTAAGTACTAAACT
Downstream 100 bases:
>100_bases TATTTCAGGAATTATTTTAGAGATTTTGAATATGGAGCAATCAGATGTTTAGAAAAAACTTAGGTATTTGGATCGGGTTA GCTATTACAATAAACGGATT
Product: chemotaxis protein histidine kinase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 713; Mature: 713
Protein sequence:
>713_residues MDLSEVRDTFISESEELLSSMESNLLILEKDSKNNEGIHSVFRAIHTIKGTSGMFGYEPIEKFTHEVESFLDRIRSNKQS LTKEGIEFLFLACDHIRNLLQGVGETLIVDSQTSRNQVNLLSLAKKLTLDDTSNPQKDEALVQNQSTSSNLLDFHSSSTF WQITLIPNIHLFESGLDPSTFIKYLSQSGKVKHIFVYPESIPNWSEFNPEHSHLGFEISYESPSKGEEIYSTFQFLKEGS YLKILSPGCSLNLFMENCNDFPLGKKAYLNALEIQKVLTPEEIQKLSYTSENLNVLSTTQTEQTTTSIENQKESDSIKIQ TKTLRVDSSKIDTLIALVGELITQEANLSRKISDSENLQLIESSESLYRLVTEIREFALSLRMIPISDLFEKYKRVVRDL SKELNKQVELEIIGGETELDRSVIEKISDPIVHILRNALDHGIETSEERIKKGKHATGQLKIQASHGTGSILIEIKDDGK GLDCDKILEKAISKGLITRDQNLSESEIYSLIFQPGFSTADQVTNLSGRGVGMDVVLRNIESLRGTVQIQTLKDQGSSFQ IRLPLTLAIIDGFLVKASSLYFIVPMQMVRETVESKVILNGSSSGTMNLRGELLPVLHLSEFLCLESTYFEKENILVLEY EDKSFGIIVNDLHGEVQSVIRPMAEIFKNIKCFSGTSILGSGEIAFILDVPGLYNSIRDQELNKNKDLVTKTG
Sequences:
>Translated_713_residues MDLSEVRDTFISESEELLSSMESNLLILEKDSKNNEGIHSVFRAIHTIKGTSGMFGYEPIEKFTHEVESFLDRIRSNKQS LTKEGIEFLFLACDHIRNLLQGVGETLIVDSQTSRNQVNLLSLAKKLTLDDTSNPQKDEALVQNQSTSSNLLDFHSSSTF WQITLIPNIHLFESGLDPSTFIKYLSQSGKVKHIFVYPESIPNWSEFNPEHSHLGFEISYESPSKGEEIYSTFQFLKEGS YLKILSPGCSLNLFMENCNDFPLGKKAYLNALEIQKVLTPEEIQKLSYTSENLNVLSTTQTEQTTTSIENQKESDSIKIQ TKTLRVDSSKIDTLIALVGELITQEANLSRKISDSENLQLIESSESLYRLVTEIREFALSLRMIPISDLFEKYKRVVRDL SKELNKQVELEIIGGETELDRSVIEKISDPIVHILRNALDHGIETSEERIKKGKHATGQLKIQASHGTGSILIEIKDDGK GLDCDKILEKAISKGLITRDQNLSESEIYSLIFQPGFSTADQVTNLSGRGVGMDVVLRNIESLRGTVQIQTLKDQGSSFQ IRLPLTLAIIDGFLVKASSLYFIVPMQMVRETVESKVILNGSSSGTMNLRGELLPVLHLSEFLCLESTYFEKENILVLEY EDKSFGIIVNDLHGEVQSVIRPMAEIFKNIKCFSGTSILGSGEIAFILDVPGLYNSIRDQELNKNKDLVTKTG >Mature_713_residues MDLSEVRDTFISESEELLSSMESNLLILEKDSKNNEGIHSVFRAIHTIKGTSGMFGYEPIEKFTHEVESFLDRIRSNKQS LTKEGIEFLFLACDHIRNLLQGVGETLIVDSQTSRNQVNLLSLAKKLTLDDTSNPQKDEALVQNQSTSSNLLDFHSSSTF WQITLIPNIHLFESGLDPSTFIKYLSQSGKVKHIFVYPESIPNWSEFNPEHSHLGFEISYESPSKGEEIYSTFQFLKEGS YLKILSPGCSLNLFMENCNDFPLGKKAYLNALEIQKVLTPEEIQKLSYTSENLNVLSTTQTEQTTTSIENQKESDSIKIQ TKTLRVDSSKIDTLIALVGELITQEANLSRKISDSENLQLIESSESLYRLVTEIREFALSLRMIPISDLFEKYKRVVRDL SKELNKQVELEIIGGETELDRSVIEKISDPIVHILRNALDHGIETSEERIKKGKHATGQLKIQASHGTGSILIEIKDDGK GLDCDKILEKAISKGLITRDQNLSESEIYSLIFQPGFSTADQVTNLSGRGVGMDVVLRNIESLRGTVQIQTLKDQGSSFQ IRLPLTLAIIDGFLVKASSLYFIVPMQMVRETVESKVILNGSSSGTMNLRGELLPVLHLSEFLCLESTYFEKENILVLEY EDKSFGIIVNDLHGEVQSVIRPMAEIFKNIKCFSGTSILGSGEIAFILDVPGLYNSIRDQELNKNKDLVTKTG
Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]
COG id: COG0643
COG function: function code NT; Chemotaxis protein histidine kinase and related kinases
Gene ontology:
Cell location: Membrane (Potential). Note=It is not known whether CheA is actually membrane bound although CheA has two regions at the C-terminal end with the potential to be transmembrane regions [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HPt domain [H]
Homologues:
Organism=Escherichia coli, GI1788197, Length=416, Percent_Identity=39.1826923076923, Blast_Score=298, Evalue=6e-82,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR002545 - InterPro: IPR004358 - InterPro: IPR008207 - InterPro: IPR004105 - InterPro: IPR005467 - InterPro: IPR009082 - InterPro: IPR010808 [H]
Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 80008; Mature: 80008
Theoretical pI: Translated: 4.83; Mature: 4.83
Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDLSEVRDTFISESEELLSSMESNLLILEKDSKNNEGIHSVFRAIHTIKGTSGMFGYEPI CCHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHH EKFTHEVESFLDRIRSNKQSLTKEGIEFLFLACDHIRNLLQGVGETLIVDSQTSRNQVNL HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH LSLAKKLTLDDTSNPQKDEALVQNQSTSSNLLDFHSSSTFWQITLIPNIHLFESGLDPST HHHHHHHCCCCCCCCCHHHHHHHCCCCCCCHHEECCCCCEEEEEEECCEEEECCCCCHHH FIKYLSQSGKVKHIFVYPESIPNWSEFNPEHSHLGFEISYESPSKGEEIYSTFQFLKEGS HHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCC YLKILSPGCSLNLFMENCNDFPLGKKAYLNALEIQKVLTPEEIQKLSYTSENLNVLSTTQ EEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECC TEQTTTSIENQKESDSIKIQTKTLRVDSSKIDTLIALVGELITQEANLSRKISDSENLQL CHHHHHHHCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE IESSESLYRLVTEIREFALSLRMIPISDLFEKYKRVVRDLSKELNKQVELEIIGGETELD EECHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHH RSVIEKISDPIVHILRNALDHGIETSEERIKKGKHATGQLKIQASHGTGSILIEIKDDGK HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCC GLDCDKILEKAISKGLITRDQNLSESEIYSLIFQPGFSTADQVTNLSGRGVGMDVVLRNI CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHH ESLRGTVQIQTLKDQGSSFQIRLPLTLAIIDGFLVKASSLYFIVPMQMVRETVESKVILN HHHCCEEEEEEECCCCCEEEEEECCHHHHHHHHHHHCCCEEEEECHHHHHHHHHCEEEEE GSSSGTMNLRGELLPVLHLSEFLCLESTYFEKENILVLEYEDKSFGIIVNDLHGEVQSVI CCCCCEEEECCCHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCCEEEEHHHHHHHHHH RPMAEIFKNIKCFSGTSILGSGEIAFILDVPGLYNSIRDQELNKNKDLVTKTG HHHHHHHHCCEECCCCEEECCCCEEEEEECCHHHHHHHHHHCCCCCCCEECCC >Mature Secondary Structure MDLSEVRDTFISESEELLSSMESNLLILEKDSKNNEGIHSVFRAIHTIKGTSGMFGYEPI CCHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHH EKFTHEVESFLDRIRSNKQSLTKEGIEFLFLACDHIRNLLQGVGETLIVDSQTSRNQVNL HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH LSLAKKLTLDDTSNPQKDEALVQNQSTSSNLLDFHSSSTFWQITLIPNIHLFESGLDPST HHHHHHHCCCCCCCCCHHHHHHHCCCCCCCHHEECCCCCEEEEEEECCEEEECCCCCHHH FIKYLSQSGKVKHIFVYPESIPNWSEFNPEHSHLGFEISYESPSKGEEIYSTFQFLKEGS HHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCC YLKILSPGCSLNLFMENCNDFPLGKKAYLNALEIQKVLTPEEIQKLSYTSENLNVLSTTQ EEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECC TEQTTTSIENQKESDSIKIQTKTLRVDSSKIDTLIALVGELITQEANLSRKISDSENLQL CHHHHHHHCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE IESSESLYRLVTEIREFALSLRMIPISDLFEKYKRVVRDLSKELNKQVELEIIGGETELD EECHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHH RSVIEKISDPIVHILRNALDHGIETSEERIKKGKHATGQLKIQASHGTGSILIEIKDDGK HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCC GLDCDKILEKAISKGLITRDQNLSESEIYSLIFQPGFSTADQVTNLSGRGVGMDVVLRNI CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHH ESLRGTVQIQTLKDQGSSFQIRLPLTLAIIDGFLVKASSLYFIVPMQMVRETVESKVILN HHHCCEEEEEEECCCCCEEEEEECCHHHHHHHHHHHCCCEEEEECHHHHHHHHHCEEEEE GSSSGTMNLRGELLPVLHLSEFLCLESTYFEKENILVLEYEDKSFGIIVNDLHGEVQSVI CCCCCEEEECCCHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCCEEEEHHHHHHHHHH RPMAEIFKNIKCFSGTSILGSGEIAFILDVPGLYNSIRDQELNKNKDLVTKTG HHHHHHHHCCEECCCCEEECCCCEEEEEECCHHHHHHHHHHCCCCCCCEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1938941; 9384377 [H]