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The map label for this gene is ttuD [H]

Identifier: 45657321

GI number: 45657321

Start: 1781344

End: 1782687

Strand: Reverse

Name: ttuD [H]

Synonym: LIC11445

Alternate gene names: 45657321

Gene position: 1782687-1781344 (Counterclockwise)

Preceding gene: 45657324

Following gene: 45657319

Centisome position: 41.68

GC content: 36.61

Gene sequence:

>1344_bases
ATGCCACGTCTCTCTTTTTTAAACAACGAAAAAGTAGACCTTCATTCTACTCAATCCATCTTATTTCATTTAGGTGGAGT
TGCAATTCGAAACTCTTTGCCCGGACCTTCCGTTCGTAAGTTTTTATTAGAACAAAAACCAAAGGGAAGAATTCTACTAC
TTTCTATCGGAAAAGCAGCAGAAGAAATGGCTAACGCCGCTTATGAAATCCTACAATCTCAGATTTTCGGAGGAATTATT
CTCACAAAATACGGATATACTTCGGGAAAAAAATTTCCACCTTTAGAAATTTTAGAAGCGGGACATCCAATCCCAGATAC
AAACAGCATATTAGGTGGAAAAAAAATCCTAGAACTCTGTTCCAATTTACGAGAAGACGACATTGTTTTAATACTTCTTT
CTGGAGGAGGTTCCGCTTTAATGGAAGTACCTGAATCCGGTCTAAATTTGGAAGATCTGATCGTTTGGAATTCTAAACTT
ATTTCCTGTGGAGCAGACATTCAAGAAATCAATTCGGTAAGAACTCTTTTATCCTCTATCAAAGGTGGTGGATTACTTAC
AAAAATTCTTCCTTCAAAATCGATCACCTTAATCCTATCGGACGTAATTGGAGACGACCTTTCCAAAGTAGCGTCCGGAC
CAACGATTCCTTCTAAAATCGAAAAAAATTCTATTTTAAGAATATTCAAACAATATAATCTACCTTTAGATCCTAAAATC
GAAACTATACTACACAAAAAAACAGAACAATCCATAAAAATCTCAAATCAGAAAATCAAATCTAAAAACTTTTCAGCAGA
ATATAAAATCGATCCTAATAAAAATTCCGTCCATTGTATCGGAAACATAACCCAAGCACTTGACGCAGTTCAGAAAGAAT
GCATAAATTTGAATATTCCAGTTCTATTGCTTACTTCTTCTTTAAATTGCGAAGCAAAAGAAGCTGGCTTCTTTTTAGGA
GAAATTGCAAAAGAAAATCTGAAAAATAAAAACTCTCCGCTTTTAATTCTCTGTGGAGGAGAAACCACGGTAACTCACGA
CGGCTCCGGAAAAGGAGGAAGAAACCAAGAATTAGCACTTGCTTTCTCAAAACGAATTTCTGGTTGTCAAGGAATCACTT
TATTCTCACTCGCAACAGACGGAAGCGACGGACCTACGGACGCAGCAGGGGCAATCGTAGATGGAACCACTTGGAAAAAA
ATTTACAGAAACAAAGACGCAAACTTGGCTCTAAAAACGCATAACTCTTACGAAGTGTTAGCTCAGGTCAATTCCTTGGT
TTTTACGGATGCGACAGGAACCAACGTAAACGACATTCAATTTTTATTGATTACTACATTTTAA

Upstream 100 bases:

>100_bases
AATAACTTTCTAAAATCCACGAAACAAGACGTCCAACTTTCATGACGATTTTAACTAAAAACGTTTCTTTTTTAAAAGGA
TCTTTTGTTTTTGGAATCCA

Downstream 100 bases:

>100_bases
AAATTTTTTCCTACTCAATCGCAGATCTTTCAATTTATTTGGTTTTTGACTCGAGTTTTTTCAATGACAAAAATTTTCTT
TTAAAAACGTTAGTTTAGTA

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MPRLSFLNNEKVDLHSTQSILFHLGGVAIRNSLPGPSVRKFLLEQKPKGRILLLSIGKAAEEMANAAYEILQSQIFGGII
LTKYGYTSGKKFPPLEILEAGHPIPDTNSILGGKKILELCSNLREDDIVLILLSGGGSALMEVPESGLNLEDLIVWNSKL
ISCGADIQEINSVRTLLSSIKGGGLLTKILPSKSITLILSDVIGDDLSKVASGPTIPSKIEKNSILRIFKQYNLPLDPKI
ETILHKKTEQSIKISNQKIKSKNFSAEYKIDPNKNSVHCIGNITQALDAVQKECINLNIPVLLLTSSLNCEAKEAGFFLG
EIAKENLKNKNSPLLILCGGETTVTHDGSGKGGRNQELALAFSKRISGCQGITLFSLATDGSDGPTDAAGAIVDGTTWKK
IYRNKDANLALKTHNSYEVLAQVNSLVFTDATGTNVNDIQFLLITTF

Sequences:

>Translated_447_residues
MPRLSFLNNEKVDLHSTQSILFHLGGVAIRNSLPGPSVRKFLLEQKPKGRILLLSIGKAAEEMANAAYEILQSQIFGGII
LTKYGYTSGKKFPPLEILEAGHPIPDTNSILGGKKILELCSNLREDDIVLILLSGGGSALMEVPESGLNLEDLIVWNSKL
ISCGADIQEINSVRTLLSSIKGGGLLTKILPSKSITLILSDVIGDDLSKVASGPTIPSKIEKNSILRIFKQYNLPLDPKI
ETILHKKTEQSIKISNQKIKSKNFSAEYKIDPNKNSVHCIGNITQALDAVQKECINLNIPVLLLTSSLNCEAKEAGFFLG
EIAKENLKNKNSPLLILCGGETTVTHDGSGKGGRNQELALAFSKRISGCQGITLFSLATDGSDGPTDAAGAIVDGTTWKK
IYRNKDANLALKTHNSYEVLAQVNSLVFTDATGTNVNDIQFLLITTF
>Mature_446_residues
PRLSFLNNEKVDLHSTQSILFHLGGVAIRNSLPGPSVRKFLLEQKPKGRILLLSIGKAAEEMANAAYEILQSQIFGGIIL
TKYGYTSGKKFPPLEILEAGHPIPDTNSILGGKKILELCSNLREDDIVLILLSGGGSALMEVPESGLNLEDLIVWNSKLI
SCGADIQEINSVRTLLSSIKGGGLLTKILPSKSITLILSDVIGDDLSKVASGPTIPSKIEKNSILRIFKQYNLPLDPKIE
TILHKKTEQSIKISNQKIKSKNFSAEYKIDPNKNSVHCIGNITQALDAVQKECINLNIPVLLLTSSLNCEAKEAGFFLGE
IAKENLKNKNSPLLILCGGETTVTHDGSGKGGRNQELALAFSKRISGCQGITLFSLATDGSDGPTDAAGAIVDGTTWKKI
YRNKDANLALKTHNSYEVLAQVNSLVFTDATGTNVNDIQFLLITTF

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=506, Percent_Identity=27.8656126482213, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI193205461, Length=434, Percent_Identity=32.9493087557604, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI19920578, Length=432, Percent_Identity=32.4074074074074, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 48276; Mature: 48145

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLSFLNNEKVDLHSTQSILFHLGGVAIRNSLPGPSVRKFLLEQKPKGRILLLSIGKAA
CCCCCCCCCCCEECHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCCEEEEECCHHH
EEMANAAYEILQSQIFGGIILTKYGYTSGKKFPPLEILEAGHPIPDTNSILGGKKILELC
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHH
SNLREDDIVLILLSGGGSALMEVPESGLNLEDLIVWNSKLISCGADIQEINSVRTLLSSI
HCCCCCCEEEEEECCCCHHHHHCCCCCCCHHHEEEECCEEEECCCCHHHHHHHHHHHHHC
KGGGLLTKILPSKSITLILSDVIGDDLSKVASGPTIPSKIEKNSILRIFKQYNLPLDPKI
CCCCEEEECCCCCCEEEEEHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
ETILHKKTEQSIKISNQKIKSKNFSAEYKIDPNKNSVHCIGNITQALDAVQKECINLNIP
HHHHHHHHHHHEEECCHHHCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCCC
VLLLTSSLNCEAKEAGFFLGEIAKENLKNKNSPLLILCGGETTVTHDGSGKGGRNQELAL
EEEEECCCCCCHHHHCHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCCCCCCHHHH
AFSKRISGCQGITLFSLATDGSDGPTDAAGAIVDGTTWKKIYRNKDANLALKTHNSYEVL
HHHHHCCCCCCEEEEEEECCCCCCCCCCCCEEECCCHHHHHHCCCCCCEEEEECCCHHHH
AQVNSLVFTDATGTNVNDIQFLLITTF
HHHHHEEEECCCCCCCCCEEEEEEEEC
>Mature Secondary Structure 
PRLSFLNNEKVDLHSTQSILFHLGGVAIRNSLPGPSVRKFLLEQKPKGRILLLSIGKAA
CCCCCCCCCCEECHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCCEEEEECCHHH
EEMANAAYEILQSQIFGGIILTKYGYTSGKKFPPLEILEAGHPIPDTNSILGGKKILELC
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHH
SNLREDDIVLILLSGGGSALMEVPESGLNLEDLIVWNSKLISCGADIQEINSVRTLLSSI
HCCCCCCEEEEEECCCCHHHHHCCCCCCCHHHEEEECCEEEECCCCHHHHHHHHHHHHHC
KGGGLLTKILPSKSITLILSDVIGDDLSKVASGPTIPSKIEKNSILRIFKQYNLPLDPKI
CCCCEEEECCCCCCEEEEEHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
ETILHKKTEQSIKISNQKIKSKNFSAEYKIDPNKNSVHCIGNITQALDAVQKECINLNIP
HHHHHHHHHHHEEECCHHHCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCCC
VLLLTSSLNCEAKEAGFFLGEIAKENLKNKNSPLLILCGGETTVTHDGSGKGGRNQELAL
EEEEECCCCCCHHHHCHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCCCCCCHHHH
AFSKRISGCQGITLFSLATDGSDGPTDAAGAIVDGTTWKKIYRNKDANLALKTHNSYEVL
HHHHHCCCCCCEEEEEEECCCCCCCCCCCCEEECCCHHHHHHCCCCCCEEEEECCCHHHH
AQVNSLVFTDATGTNVNDIQFLLITTF
HHHHHEEEECCCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]