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The map label for this gene is mmgC [H]

Identifier: 45657228

GI number: 45657228

Start: 1663262

End: 1665022

Strand: Reverse

Name: mmgC [H]

Synonym: LIC11350

Alternate gene names: 45657228

Gene position: 1665022-1663262 (Counterclockwise)

Preceding gene: 45657230

Following gene: 45657227

Centisome position: 38.93

GC content: 37.37

Gene sequence:

>1761_bases
ATGATCGAAAATAATTACTTTTTAGAAAACCAAGATTTACAGGAAAATTTTCAATTTATCATAGATTGGAAAGAGATCAT
AGATGGTTTTGAAGACGATTTTGCTGATCATAAAATCTTTCAAAAAAACGGAAATGAATCCTTATCGATGGCTCCCGGTT
CCCATGACGAAGCATTAGAATATTATAAATCTATTTTAGAGTCCGGTGGTGAAATAGCAGGAAAACAAATCGCACCTATC
TCAAAAGATATGGACTCGGAGGGTTTAAAATATTCATCCGGAAAAGTTACTTTTCCAGAAACTATGATCAAAGGGATAGA
ACAGGTAAAAAACTCAGGAATTCTTCCCTACAGCATAGGAAGAAAACACGGCGGACTCGGAGTTCCTGCAACCGTTCAAT
GTATGATGTTGGAGTTATTTTCCAGAGCCGATGGCTCTTTTGCGATCGCACTTGGATGTCTCAACTTGGCAGAAACCATA
GAACGTTTTGGTTCCAAGGAAATGATAGATGAATACGTTCCTAAAATGGCAAACGGAGAAATTTTTGGAGCCATGGCTTT
GACAGAACCGAACTACGGATCGGATCTTCCGAATCTACAAACCAAAGCCATAAAAGACGAAAATGGAATCTGGAAACTCA
CCGGAACCAAACGTTTTATCACCCACGGTTGCGGATTTGCTAATATTCCAGCTGTAATTTTGACACTTGCAAGAACTGGA
ACCCCCACAAGCGGAGCTCGTGGTCTTTCTTTTTTCTTAGTAAAAAGTTCGGACGTTTTTATTGCCGGAATCGAAAAGAA
AATGGGACTCCACTGTTCTCCTACTTGTGAAGTGGTCTATGAAAATACTCCCGGAATTTTAATTGGTGAAGAAGGATATG
GTTTAGTCCGTTATTCTATGGCAATGATGAACGGTGCTAGACTTTCGATCGCTGCACAAGCAATGGGAATTGCAACAGCC
GCTTATATGGAAGCTAAAAAATATGCCTCCGAAAGAGAACAATTTGGAAAAAAAATTCAAAATATTCCCGCCGTCCATAA
AATGTTATCCTTTATGGATAGAGAAATTGCTGGAATGAGAGCAATTTTATTGGAAGCCTCTCGTTCTATCGATCTCTATC
ACTGGAAATCAGAAAGGATGAGAGAAAATGGAATAGAAGAAAGAGAAATCAAAAAAGATGAAACAATTCGCAAATGGGAA
AAATTAGCTAATCTTTTTACTCCATTATCAAAATATTATATTACAGAACTTGCAAATAAAATAGCATACGATGCCCTTCA
AATTCACGGAGGAGCGGGTTTTACTTACGACTACGACGTTTCTAGAATTTATAGAGACGTTCGAATTACAAATATTTACG
AAGGAACAACTCAACTTCAAGTTGTTGCGGCAATCGGAGGAATTGTATCCGGTATGTCTCCCAAAGGTCATTTACGTCAG
TATTTTGAGGAAGAGTTTTCTAAAATTGGTGGCGGTTCTACTTTGTTAAACGAAAACAAGGATTCTTTAGAAAAGATAGT
AGAATCCTATTCTTCGATCGAAAATTCATCCTTAAGAGACGAAGTCGCTTTTGAAGTGGTTCAATCTGCTGCAAGAATTT
TGATAGGTTTACTTTTGGAAAAAGGAGCTTCCAAACTCAACGGCGAAACAAAGAAAAAAAGAGAAATTCTCGCCAGAGAT
TATAATCTCGAATCAAAAGCCATTCTTCTTTCAAATCGAATTATAATTGAAAATCGTCAAACTCAACTAACGTTTGTATA
A

Upstream 100 bases:

>100_bases
TAAAATTAGAATTACGAATTGAACTCGTCTCAGAAGAATTTTAATTTTATAAGCCATAAAAAGATTCAAAAATAATAAAA
TATTCAAAAAGAGATTTAAC

Downstream 100 bases:

>100_bases
TCAATGAAACTTAAGATTTGTTTTATGATGACACTTTGATAAACTATTTCTCTATAGAAAATTCAATTTGAAACCTAAAG
TAGTAATTCAAATCTACAAA

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MIENNYFLENQDLQENFQFIIDWKEIIDGFEDDFADHKIFQKNGNESLSMAPGSHDEALEYYKSILESGGEIAGKQIAPI
SKDMDSEGLKYSSGKVTFPETMIKGIEQVKNSGILPYSIGRKHGGLGVPATVQCMMLELFSRADGSFAIALGCLNLAETI
ERFGSKEMIDEYVPKMANGEIFGAMALTEPNYGSDLPNLQTKAIKDENGIWKLTGTKRFITHGCGFANIPAVILTLARTG
TPTSGARGLSFFLVKSSDVFIAGIEKKMGLHCSPTCEVVYENTPGILIGEEGYGLVRYSMAMMNGARLSIAAQAMGIATA
AYMEAKKYASEREQFGKKIQNIPAVHKMLSFMDREIAGMRAILLEASRSIDLYHWKSERMRENGIEEREIKKDETIRKWE
KLANLFTPLSKYYITELANKIAYDALQIHGGAGFTYDYDVSRIYRDVRITNIYEGTTQLQVVAAIGGIVSGMSPKGHLRQ
YFEEEFSKIGGGSTLLNENKDSLEKIVESYSSIENSSLRDEVAFEVVQSAARILIGLLLEKGASKLNGETKKKREILARD
YNLESKAILLSNRIIIENRQTQLTFV

Sequences:

>Translated_586_residues
MIENNYFLENQDLQENFQFIIDWKEIIDGFEDDFADHKIFQKNGNESLSMAPGSHDEALEYYKSILESGGEIAGKQIAPI
SKDMDSEGLKYSSGKVTFPETMIKGIEQVKNSGILPYSIGRKHGGLGVPATVQCMMLELFSRADGSFAIALGCLNLAETI
ERFGSKEMIDEYVPKMANGEIFGAMALTEPNYGSDLPNLQTKAIKDENGIWKLTGTKRFITHGCGFANIPAVILTLARTG
TPTSGARGLSFFLVKSSDVFIAGIEKKMGLHCSPTCEVVYENTPGILIGEEGYGLVRYSMAMMNGARLSIAAQAMGIATA
AYMEAKKYASEREQFGKKIQNIPAVHKMLSFMDREIAGMRAILLEASRSIDLYHWKSERMRENGIEEREIKKDETIRKWE
KLANLFTPLSKYYITELANKIAYDALQIHGGAGFTYDYDVSRIYRDVRITNIYEGTTQLQVVAAIGGIVSGMSPKGHLRQ
YFEEEFSKIGGGSTLLNENKDSLEKIVESYSSIENSSLRDEVAFEVVQSAARILIGLLLEKGASKLNGETKKKREILARD
YNLESKAILLSNRIIIENRQTQLTFV
>Mature_586_residues
MIENNYFLENQDLQENFQFIIDWKEIIDGFEDDFADHKIFQKNGNESLSMAPGSHDEALEYYKSILESGGEIAGKQIAPI
SKDMDSEGLKYSSGKVTFPETMIKGIEQVKNSGILPYSIGRKHGGLGVPATVQCMMLELFSRADGSFAIALGCLNLAETI
ERFGSKEMIDEYVPKMANGEIFGAMALTEPNYGSDLPNLQTKAIKDENGIWKLTGTKRFITHGCGFANIPAVILTLARTG
TPTSGARGLSFFLVKSSDVFIAGIEKKMGLHCSPTCEVVYENTPGILIGEEGYGLVRYSMAMMNGARLSIAAQAMGIATA
AYMEAKKYASEREQFGKKIQNIPAVHKMLSFMDREIAGMRAILLEASRSIDLYHWKSERMRENGIEEREIKKDETIRKWE
KLANLFTPLSKYYITELANKIAYDALQIHGGAGFTYDYDVSRIYRDVRITNIYEGTTQLQVVAAIGGIVSGMSPKGHLRQ
YFEEEFSKIGGGSTLLNENKDSLEKIVESYSSIENSSLRDEVAFEVVQSAARILIGLLLEKGASKLNGETKKKREILARD
YNLESKAILLSNRIIIENRQTQLTFV

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=362, Percent_Identity=30.3867403314917, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI4557233, Length=420, Percent_Identity=28.0952380952381, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI4501859, Length=398, Percent_Identity=27.6381909547739, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI187960098, Length=424, Percent_Identity=29.0094339622642, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI4557231, Length=424, Percent_Identity=29.0094339622642, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI21361497, Length=372, Percent_Identity=27.9569892473118, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=28.90625, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=28.90625, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI7656849, Length=444, Percent_Identity=27.7027027027027, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI226958412, Length=364, Percent_Identity=26.9230769230769, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI226958414, Length=364, Percent_Identity=26.9230769230769, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4503943, Length=375, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI7669494, Length=358, Percent_Identity=26.2569832402235, Blast_Score=80, Evalue=8e-15,
Organism=Escherichia coli, GI87081958, Length=397, Percent_Identity=28.7153652392947, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786223, Length=372, Percent_Identity=25.5376344086022, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI87082384, Length=281, Percent_Identity=26.6903914590747, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17508101, Length=417, Percent_Identity=26.378896882494, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=30.5851063829787, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17538396, Length=418, Percent_Identity=26.7942583732057, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17506239, Length=392, Percent_Identity=23.9795918367347, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17569725, Length=423, Percent_Identity=28.3687943262411, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17570075, Length=365, Percent_Identity=29.3150684931507, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71985184, Length=340, Percent_Identity=28.8235294117647, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=403, Percent_Identity=25.8064516129032, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI86563383, Length=445, Percent_Identity=24.9438202247191, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=445, Percent_Identity=24.9438202247191, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71990804, Length=264, Percent_Identity=26.8939393939394, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=325, Percent_Identity=25.2307692307692, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71982178, Length=288, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=249, Percent_Identity=24.4979919678715, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=219, Percent_Identity=31.0502283105023, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17551932, Length=303, Percent_Identity=25.7425742574257, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=303, Percent_Identity=24.0924092409241, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24666513, Length=406, Percent_Identity=29.064039408867, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24660351, Length=388, Percent_Identity=31.701030927835, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI21356377, Length=379, Percent_Identity=27.9683377308707, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24646207, Length=415, Percent_Identity=25.7831325301205, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI21355753, Length=396, Percent_Identity=26.2626262626263, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI281363737, Length=389, Percent_Identity=26.9922879177378, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI19920834, Length=275, Percent_Identity=30.5454545454545, Blast_Score=85, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 65218; Mature: 65218

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIENNYFLENQDLQENFQFIIDWKEIIDGFEDDFADHKIFQKNGNESLSMAPGSHDEALE
CCCCCEEECCCCHHHHHHEEEEHHHHHCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHH
YYKSILESGGEIAGKQIAPISKDMDSEGLKYSSGKVTFPETMIKGIEQVKNSGILPYSIG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCEECHHHHHHHHHHHHHCCCCEEECC
RKHGGLGVPATVQCMMLELFSRADGSFAIALGCLNLAETIERFGSKEMIDEYVPKMANGE
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHCCHHCCCC
IFGAMALTEPNYGSDLPNLQTKAIKDENGIWKLTGTKRFITHGCGFANIPAVILTLARTG
EEEEEEECCCCCCCCCCCCCHHHEECCCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHCC
TPTSGARGLSFFLVKSSDVFIAGIEKKMGLHCSPTCEVVYENTPGILIGEEGYGLVRYSM
CCCCCCCCEEEEEEECCCEEEEECHHHCCCCCCCCEEEEEECCCCEEECCCCCCHHHHHH
AMMNGARLSIAAQAMGIATAAYMEAKKYASEREQFGKKIQNIPAVHKMLSFMDREIAGMR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AILLEASRSIDLYHWKSERMRENGIEEREIKKDETIRKWEKLANLFTPLSKYYITELANK
HHHHHHCCCEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAYDALQIHGGAGFTYDYDVSRIYRDVRITNIYEGTTQLQVVAAIGGIVSGMSPKGHLRQ
HHHHHHEEECCCCCEEECCHHHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHH
YFEEEFSKIGGGSTLLNENKDSLEKIVESYSSIENSSLRDEVAFEVVQSAARILIGLLLE
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
KGASKLNGETKKKREILARDYNLESKAILLSNRIIIENRQTQLTFV
HCHHHCCCCHHHHHHHHHHCCCCCCCEEEEECEEEEECCCCEEEEC
>Mature Secondary Structure
MIENNYFLENQDLQENFQFIIDWKEIIDGFEDDFADHKIFQKNGNESLSMAPGSHDEALE
CCCCCEEECCCCHHHHHHEEEEHHHHHCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHH
YYKSILESGGEIAGKQIAPISKDMDSEGLKYSSGKVTFPETMIKGIEQVKNSGILPYSIG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCEECHHHHHHHHHHHHHCCCCEEECC
RKHGGLGVPATVQCMMLELFSRADGSFAIALGCLNLAETIERFGSKEMIDEYVPKMANGE
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHCCHHCCCC
IFGAMALTEPNYGSDLPNLQTKAIKDENGIWKLTGTKRFITHGCGFANIPAVILTLARTG
EEEEEEECCCCCCCCCCCCCHHHEECCCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHCC
TPTSGARGLSFFLVKSSDVFIAGIEKKMGLHCSPTCEVVYENTPGILIGEEGYGLVRYSM
CCCCCCCCEEEEEEECCCEEEEECHHHCCCCCCCCEEEEEECCCCEEECCCCCCHHHHHH
AMMNGARLSIAAQAMGIATAAYMEAKKYASEREQFGKKIQNIPAVHKMLSFMDREIAGMR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AILLEASRSIDLYHWKSERMRENGIEEREIKKDETIRKWEKLANLFTPLSKYYITELANK
HHHHHHCCCEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAYDALQIHGGAGFTYDYDVSRIYRDVRITNIYEGTTQLQVVAAIGGIVSGMSPKGHLRQ
HHHHHHEEECCCCCEEECCHHHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHH
YFEEEFSKIGGGSTLLNENKDSLEKIVESYSSIENSSLRDEVAFEVVQSAARILIGLLLE
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
KGASKLNGETKKKREILARDYNLESKAILLSNRIIIENRQTQLTFV
HCHHHCCCCHHHHHHHHHHCCCCCCCEEEEECEEEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]