| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is ppx
Identifier: 45657140
GI number: 45657140
Start: 1552572
End: 1554134
Strand: Reverse
Name: ppx
Synonym: LIC11257
Alternate gene names: 45657140
Gene position: 1554134-1552572 (Counterclockwise)
Preceding gene: 45657147
Following gene: 45657139
Centisome position: 36.34
GC content: 37.36
Gene sequence:
>1563_bases ATGGTTCAAGAAAAACCTCTCGCTGCCATCGACCTTGGCACCAACTCATTTCACATGATCATCGTTCGAGTTCGAACAAA CGGAACTTTCGAAGCCATCGCTAGAGAAAAAGAATCAGTTCGCTTAGGTAATAGGTTGCAAGAAAACGGTCCGATCGATC CGGAATCGTTTCGTAGAGGAATCGATTGTCTCAAAAGATTTAAGATCTTAGCAGAAAACGCAGGAGCAGAAATCAGAGCC GTTGCTACAAGCGCACTACGAGAAGCTTCTAACCAAGAAGACTTTTTAGAAAACGCATATCAAGAAGCGGGTATATCCAT CGATGTAGTAAGTGGTTATGAAGAAGCCCGACTCATTTACTTTGGAATTCTCCAAGGAATTCCAGTTTTTGATCGAAAAA TCATGATGATCGATATAGGCGGAGGAAGTACTGAAATTTTAGTAGGTCATAGAGGAAATATTTTATTCTCTAAAAGTTTT AAACTGGGGGCCATCCGACTTTCAGAAAAATTCTTTAAAGAAGAAACTCTTTCTAACTCGGATGTTCGTAAATGTAGACT TTACATCGAAGAAATGCTTCTTCCTTTTCGAAAAATTCTCAGAGATTTAAAACCGGACTTGGTAGTAGGTTCATCTGGAA CGATACAATCGATCGCGGGTATGATTTTAGCATCCAGAGGGGAAACGGAAGAAATCTCTTTAAACAATTTCTCATTTACT TCTTCCGAATTTAAAAAAATCCGTAATCTAATTTTAGAAGCGGATACTTCTAAAAAAAGATCCAAGATCCCAGGTTTAGA TAGCAAACGAGCAGACATCATCGTTGGAGGAACTTTGATTTTAGAAGAAATTTTTGATCTTGCAAACGTTTCTGCTTTAA CCGTTTCCGAATTCGCTCTTCGAGAAGGAATTGTATACGATACAATTCGCAAATGGGAACACTTCGAAAACACAGAACAT TCTAAACACTTAGATGACATCCGTCAAACAGCAGTTCATAATTTTATGAAATCCTTTTCTAGAGACGAAGAATTTTCAAA ACACGTCGCTGAATTAAGTCTTCAGATTTTTGATCAATTAAAAAGTTTGCATAAACTGGGGCAGGAACAAAGAGAACTTT TAGAAGCGGCTTCTCTTTTACACGAAATCGGTCAGTCGATTTCACATTCCGCCTATCATAAGCACAGTTATTATATGATC CGAAATTCGGAAATGCTTTTAGGTTTTACTTTTTTAGAAATTGAAATCATCGCTTTGACCGCTCGTTATCATAGAAAGAA TACTCCTAAAATTAAACACAGGGAATTTAATAAGCTCGCTGAAAAAAATCAAACCTTAGTATGTCAACTTTCTGCGATCC TAAGAATTAGCTCCGCGTTAAACCGAAATCGAGGTGGACTAGTTTCTTCAGTAATTTGTAAAATCGAAAAAAATCAGATT CGTTTTATTTTAGAATCCAGTAAGGGTTACGATCCTTCTTTAGAAATTTGGGCCGCGGAAGAACAAAAGGTGGCGTTCGA AGAAACCTTCGGTTATTCAGTGGAATTTGTAACTGGAACTTAA
Upstream 100 bases:
>100_bases AATAATTTCAACGCTTGGGTTCCCGGCAACCTCAAAACAAAAAATTCAGAAAACAAATTAAGCTGGATTCGATTTTAGTA GCAAAGCATTCTGTTCAACC
Downstream 100 bases:
>100_bases AAATACAAAATCGTTCTTTTTTTTGTTGGAAATTGTGGTTAGCTGTTTTTCTTCACATTCAATCAAAAAGATTTCCAACA CAACTTTATTCGTTTCAAAT
Product: exopolyphosphatase
Products: NA
Alternate protein names: ExopolyPase; Metaphosphatase [H]
Number of amino acids: Translated: 520; Mature: 520
Protein sequence:
>520_residues MVQEKPLAAIDLGTNSFHMIIVRVRTNGTFEAIAREKESVRLGNRLQENGPIDPESFRRGIDCLKRFKILAENAGAEIRA VATSALREASNQEDFLENAYQEAGISIDVVSGYEEARLIYFGILQGIPVFDRKIMMIDIGGGSTEILVGHRGNILFSKSF KLGAIRLSEKFFKEETLSNSDVRKCRLYIEEMLLPFRKILRDLKPDLVVGSSGTIQSIAGMILASRGETEEISLNNFSFT SSEFKKIRNLILEADTSKKRSKIPGLDSKRADIIVGGTLILEEIFDLANVSALTVSEFALREGIVYDTIRKWEHFENTEH SKHLDDIRQTAVHNFMKSFSRDEEFSKHVAELSLQIFDQLKSLHKLGQEQRELLEAASLLHEIGQSISHSAYHKHSYYMI RNSEMLLGFTFLEIEIIALTARYHRKNTPKIKHREFNKLAEKNQTLVCQLSAILRISSALNRNRGGLVSSVICKIEKNQI RFILESSKGYDPSLEIWAAEEQKVAFEETFGYSVEFVTGT
Sequences:
>Translated_520_residues MVQEKPLAAIDLGTNSFHMIIVRVRTNGTFEAIAREKESVRLGNRLQENGPIDPESFRRGIDCLKRFKILAENAGAEIRA VATSALREASNQEDFLENAYQEAGISIDVVSGYEEARLIYFGILQGIPVFDRKIMMIDIGGGSTEILVGHRGNILFSKSF KLGAIRLSEKFFKEETLSNSDVRKCRLYIEEMLLPFRKILRDLKPDLVVGSSGTIQSIAGMILASRGETEEISLNNFSFT SSEFKKIRNLILEADTSKKRSKIPGLDSKRADIIVGGTLILEEIFDLANVSALTVSEFALREGIVYDTIRKWEHFENTEH SKHLDDIRQTAVHNFMKSFSRDEEFSKHVAELSLQIFDQLKSLHKLGQEQRELLEAASLLHEIGQSISHSAYHKHSYYMI RNSEMLLGFTFLEIEIIALTARYHRKNTPKIKHREFNKLAEKNQTLVCQLSAILRISSALNRNRGGLVSSVICKIEKNQI RFILESSKGYDPSLEIWAAEEQKVAFEETFGYSVEFVTGT >Mature_520_residues MVQEKPLAAIDLGTNSFHMIIVRVRTNGTFEAIAREKESVRLGNRLQENGPIDPESFRRGIDCLKRFKILAENAGAEIRA VATSALREASNQEDFLENAYQEAGISIDVVSGYEEARLIYFGILQGIPVFDRKIMMIDIGGGSTEILVGHRGNILFSKSF KLGAIRLSEKFFKEETLSNSDVRKCRLYIEEMLLPFRKILRDLKPDLVVGSSGTIQSIAGMILASRGETEEISLNNFSFT SSEFKKIRNLILEADTSKKRSKIPGLDSKRADIIVGGTLILEEIFDLANVSALTVSEFALREGIVYDTIRKWEHFENTEH SKHLDDIRQTAVHNFMKSFSRDEEFSKHVAELSLQIFDQLKSLHKLGQEQRELLEAASLLHEIGQSISHSAYHKHSYYMI RNSEMLLGFTFLEIEIIALTARYHRKNTPKIKHREFNKLAEKNQTLVCQLSAILRISSALNRNRGGLVSSVICKIEKNQI RFILESSKGYDPSLEIWAAEEQKVAFEETFGYSVEFVTGT
Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]
COG id: COG0248
COG function: function code FP; Exopolyphosphatase
Gene ontology:
Cell location: Membrane-Associated [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the gppA/ppx family [H]
Homologues:
Organism=Escherichia coli, GI1788848, Length=461, Percent_Identity=31.236442516269, Blast_Score=207, Evalue=1e-54, Organism=Escherichia coli, GI48994966, Length=414, Percent_Identity=32.6086956521739, Blast_Score=190, Evalue=2e-49,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR022371 - InterPro: IPR003695 [H]
Pfam domain/function: PF02541 Ppx-GppA [H]
EC number: =3.6.1.11 [H]
Molecular weight: Translated: 58907; Mature: 58907
Theoretical pI: Translated: 7.04; Mature: 7.04
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVQEKPLAAIDLGTNSFHMIIVRVRTNGTFEAIAREKESVRLGNRLQENGPIDPESFRRG CCCCCCCEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH IDCLKRFKILAENAGAEIRAVATSALREASNQEDFLENAYQEAGISIDVVSGYEEARLIY HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHE FGILQGIPVFDRKIMMIDIGGGSTEILVGHRGNILFSKSFKLGAIRLSEKFFKEETLSNS EHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCEEEECCCCEEEEHHHHHHHHHHHCCCC DVRKCRLYIEEMLLPFRKILRDLKPDLVVGSSGTIQSIAGMILASRGETEEISLNNFSFT HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCC SSEFKKIRNLILEADTSKKRSKIPGLDSKRADIIVGGTLILEEIFDLANVSALTVSEFAL HHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHCCCHHHHHHHHH REGIVYDTIRKWEHFENTEHSKHLDDIRQTAVHNFMKSFSRDEEFSKHVAELSLQIFDQL HCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH KSLHKLGQEQRELLEAASLLHEIGQSISHSAYHKHSYYMIRNSEMLLGFTFLEIEIIALT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEEEEEEEEEEEE ARYHRKNTPKIKHREFNKLAEKNQTLVCQLSAILRISSALNRNRGGLVSSVICKIEKNQI HHHHCCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHEECCCE RFILESSKGYDPSLEIWAAEEQKVAFEETFGYSVEFVTGT EEEEECCCCCCCCEEEEECCCCHHHHHHHCCCEEEEEECC >Mature Secondary Structure MVQEKPLAAIDLGTNSFHMIIVRVRTNGTFEAIAREKESVRLGNRLQENGPIDPESFRRG CCCCCCCEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH IDCLKRFKILAENAGAEIRAVATSALREASNQEDFLENAYQEAGISIDVVSGYEEARLIY HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHE FGILQGIPVFDRKIMMIDIGGGSTEILVGHRGNILFSKSFKLGAIRLSEKFFKEETLSNS EHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCEEEECCCCEEEEHHHHHHHHHHHCCCC DVRKCRLYIEEMLLPFRKILRDLKPDLVVGSSGTIQSIAGMILASRGETEEISLNNFSFT HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCC SSEFKKIRNLILEADTSKKRSKIPGLDSKRADIIVGGTLILEEIFDLANVSALTVSEFAL HHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHCCCHHHHHHHHH REGIVYDTIRKWEHFENTEHSKHLDDIRQTAVHNFMKSFSRDEEFSKHVAELSLQIFDQL HCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH KSLHKLGQEQRELLEAASLLHEIGQSISHSAYHKHSYYMIRNSEMLLGFTFLEIEIIALT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEEEEEEEEEEEE ARYHRKNTPKIKHREFNKLAEKNQTLVCQLSAILRISSALNRNRGGLVSSVICKIEKNQI HHHHCCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHEECCCE RFILESSKGYDPSLEIWAAEEQKVAFEETFGYSVEFVTGT EEEEECCCCCCCCEEEEECCCCHHHHHHHCCCEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10382967; 10984043 [H]