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The map label for this gene is fabG [H]

Identifier: 45657029

GI number: 45657029

Start: 1412482

End: 1413405

Strand: Reverse

Name: fabG [H]

Synonym: LIC11145

Alternate gene names: 45657029

Gene position: 1413405-1412482 (Counterclockwise)

Preceding gene: 45657036

Following gene: 45657028

Centisome position: 33.05

GC content: 35.39

Gene sequence:

>924_bases
ATGAATCAAAAAAACTTAGAAGGTAAAGTAGCATTAGTTACAGGTGCTACGAGAGGAGCCGGACGAGGAATTGCTTTGGC
CCTAGGAGAAGCGGGAGTCACCGTTTATGTTACCGGTAGAAGTATCAAAGATAAACATCCTAAAATAAATCGTAAAGAAA
CCATAGAAGAAACTGCAGAACGGATTAACAAATTAGGAGGTAAGGCAATCTGGGCGCAAGTAGACCATACAAATCCGAAA
GAAGTTAAATCTCTGTTTGAAAGGATAGATCAAGAACAAGGAAAACTGAATATTTTAGTCAACGATATATGGGGAGGTGA
TCCCTTTATCGAATGGTCTTGTAAATTTTGGGAACATTCTTTGGAAAACGGTCTTAAAGTTCAAAAGAATTGTTTAAATT
CTCATTTGATTACAAATTATTTTGCAACTCCATTGATGATTCGCAACCACTCCGGTCTAATTTTGGAAATCACCGACGGA
ACGGATTATCGTTACAGAGGAAGCGTATATTATACTTTAGTTAAATGTTCCATTATTAATCTTGCAAGTTCTTTATCAGA
AGAATTAAAACCTTACGGTGTTACTGTAATTTCATTAACTCCAGGATTTTTAAGATCCGAAGCAATGTTAGATTATTTCG
GAGTTTTGGAAGAAAATTGGAAAGACGCAATTTTAAAAGATCCTCATTTTATCGCCTCGGAAACCACTGCCTATATAGGT
CGTGCAGTCATATCTTTAGCGGAAGATCCAAATGTTTTCCTAAAAACCGGAAGTGCTACAAGTACTTGGAGACTTTCTGA
AGAATATAATTTTACGGATTTAGACGGAGTAAACCACATTGGAGACAATACTTCCGAGAAAAATTTGGAGAAGATTTATA
AAGACATGAAACAATTCTTTCAATCTAACAAGTTAGAAATTTAA

Upstream 100 bases:

>100_bases
ACTATGGATTCTTTATGTAGAACTCACGTTATTTAAGTTTAGAGAGAATTTCGAAAATATATGACATCTTTTGTCAAATT
TTTTGGATTAAAATTTTATT

Downstream 100 bases:

>100_bases
TGAAAATTCTAAATACGATTTGGGAAGTTTTGTTTTTGATCTTTTCAAGATTTTTTTATTCGAAAGAAATTTCAACCTAA
TCATGACTGAAACAAAAATA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNQKNLEGKVALVTGATRGAGRGIALALGEAGVTVYVTGRSIKDKHPKINRKETIEETAERINKLGGKAIWAQVDHTNPK
EVKSLFERIDQEQGKLNILVNDIWGGDPFIEWSCKFWEHSLENGLKVQKNCLNSHLITNYFATPLMIRNHSGLILEITDG
TDYRYRGSVYYTLVKCSIINLASSLSEELKPYGVTVISLTPGFLRSEAMLDYFGVLEENWKDAILKDPHFIASETTAYIG
RAVISLAEDPNVFLKTGSATSTWRLSEEYNFTDLDGVNHIGDNTSEKNLEKIYKDMKQFFQSNKLEI

Sequences:

>Translated_307_residues
MNQKNLEGKVALVTGATRGAGRGIALALGEAGVTVYVTGRSIKDKHPKINRKETIEETAERINKLGGKAIWAQVDHTNPK
EVKSLFERIDQEQGKLNILVNDIWGGDPFIEWSCKFWEHSLENGLKVQKNCLNSHLITNYFATPLMIRNHSGLILEITDG
TDYRYRGSVYYTLVKCSIINLASSLSEELKPYGVTVISLTPGFLRSEAMLDYFGVLEENWKDAILKDPHFIASETTAYIG
RAVISLAEDPNVFLKTGSATSTWRLSEEYNFTDLDGVNHIGDNTSEKNLEKIYKDMKQFFQSNKLEI
>Mature_307_residues
MNQKNLEGKVALVTGATRGAGRGIALALGEAGVTVYVTGRSIKDKHPKINRKETIEETAERINKLGGKAIWAQVDHTNPK
EVKSLFERIDQEQGKLNILVNDIWGGDPFIEWSCKFWEHSLENGLKVQKNCLNSHLITNYFATPLMIRNHSGLILEITDG
TDYRYRGSVYYTLVKCSIINLASSLSEELKPYGVTVISLTPGFLRSEAMLDYFGVLEENWKDAILKDPHFIASETTAYIG
RAVISLAEDPNVFLKTGSATSTWRLSEEYNFTDLDGVNHIGDNTSEKNLEKIYKDMKQFFQSNKLEI

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI209862901, Length=276, Percent_Identity=33.695652173913, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI19923983, Length=276, Percent_Identity=33.695652173913, Blast_Score=154, Evalue=7e-38,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=28.6852589641434, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI2367175, Length=211, Percent_Identity=28.9099526066351, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87082100, Length=205, Percent_Identity=26.3414634146341, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787905, Length=153, Percent_Identity=29.4117647058824, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=283, Percent_Identity=37.8091872791519, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI71997099, Length=292, Percent_Identity=34.9315068493151, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI86565303, Length=284, Percent_Identity=33.4507042253521, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71982365, Length=203, Percent_Identity=26.6009852216749, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=210, Percent_Identity=27.6190476190476, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 34514; Mature: 34514

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQKNLEGKVALVTGATRGAGRGIALALGEAGVTVYVTGRSIKDKHPKINRKETIEETAE
CCCCCCCCEEEEEEECCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
RINKLGGKAIWAQVDHTNPKEVKSLFERIDQEQGKLNILVNDIWGGDPFIEWSCKFWEHS
HHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEHHHHHHH
LENGLKVQKNCLNSHLITNYFATPLMIRNHSGLILEITDGTDYRYRGSVYYTLVKCSIIN
HHCCCHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCEEECEEEEEEEHHHHHH
LASSLSEELKPYGVTVISLTPGFLRSEAMLDYFGVLEENWKDAILKDPHFIASETTAYIG
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHH
RAVISLAEDPNVFLKTGSATSTWRLSEEYNFTDLDGVNHIGDNTSEKNLEKIYKDMKQFF
HHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QSNKLEI
HCCCCCC
>Mature Secondary Structure
MNQKNLEGKVALVTGATRGAGRGIALALGEAGVTVYVTGRSIKDKHPKINRKETIEETAE
CCCCCCCCEEEEEEECCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
RINKLGGKAIWAQVDHTNPKEVKSLFERIDQEQGKLNILVNDIWGGDPFIEWSCKFWEHS
HHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEHHHHHHH
LENGLKVQKNCLNSHLITNYFATPLMIRNHSGLILEITDGTDYRYRGSVYYTLVKCSIIN
HHCCCHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCEEECEEEEEEEHHHHHH
LASSLSEELKPYGVTVISLTPGFLRSEAMLDYFGVLEENWKDAILKDPHFIASETTAYIG
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHH
RAVISLAEDPNVFLKTGSATSTWRLSEEYNFTDLDGVNHIGDNTSEKNLEKIYKDMKQFF
HHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QSNKLEI
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA