Click here to switch to the map view.

The map label for this gene is degP [C]

Identifier: 45656996

GI number: 45656996

Start: 1374234

End: 1375688

Strand: Reverse

Name: degP [C]

Synonym: LIC11112

Alternate gene names: 45656996

Gene position: 1375688-1374234 (Counterclockwise)

Preceding gene: 45656997

Following gene: 45656995

Centisome position: 32.16

GC content: 36.22

Gene sequence:

>1455_bases
ATGAGTAAAAAAGTATTTTTAAATATTCTAATTTTATTATCTATCTTTCAACTCTCCGCACAAAACGGCAATACCGCGGA
TCTAAAAGTTCTACTGGACGGTGTGGTCATCATCCGAAGTGATACTTTTTCAGAAAAAGAAGATCAAGATAACTATTCCG
AAAAATCAATTTTACGGGACGCTGGTACCGGTATGATCATTTCCGGAAATAGGATTCTTACAAACGCACACGTTGTTTCC
AATTCCAGTTATCTCAAAGTAAAACATTTCAATTCTAGTAAATTTTATAAGGCGGAAGTTCAATACCTAGGGTTTGACTG
TGATCTTGCAATTCTCAAAGTGGAAGAAGATGAGTTTTTTAGCGGTGTAGAACCTCTGGAAATTTCGGAAGTTTCCCCCG
CCCTTGGAAGTAATCTTTTGATTTTAGGTTATCCCGGAGGAGACGAGAACATTACATTAGAAAATGGGAATGTTTCTAGA
GTGGAAAGAGTTCGTTATTCCTTTAGCGGTTTAGATTATAGAAAAGCGATCCGTGTCAATGCAAACATCATTCCGGGTTA
TTCCGGCGGACCAGCCATTCAAAACGGTAGAGTGGTGGGAATTACATTTCAAGTCAGTCAGTCTCAAGGAAACGTAGCCT
ACTTGATTCCTCCAGAAATTATCAATCACTTCTTAAAAGATGTTGAAGACGGAACCTATCACGGTTTTCCGTTTCCCGGT
TTTAGTTTTCAAAATGGTCATTCTTCTTCTTTAAAATCCTATCTTAAAATTCCAGAAGGTCTAAACGGTATTTTGATCAA
TACGATTTATCCTGATTCTTCTTTTTCAGATCTTTTACAACCGGAAGATTTTGTTTATAAAATTGATAATTCTTATTTAG
ACGGAGACGGCGGAATTATGGATGAAATAGGAGGTTTTATAGGAGACCTGATCGAAGAAAAATTTATCGGTGACCATATT
AAACTTTTCTTTTATAGAAATGGAAAAAACTACAAAGTAGAAGGAACCCTCAAACGCGTTCCTACGTTGGATATTTATAG
ACAACAAAATAAAAGTTCCAGTTTTTTATCGGGTGGTTTTTTGTTTCAGCCGGTCAATCGAGCACTCGCTGGGGGAGATT
CCAAACGTTTGGAAAGCTCTCTTAGGTATCATTACAGTTATTATATTCAAGATGAGTTATATCGTTTTACGGACAGAGAC
ATTTTACTTTCGGGTATTTATCCAGATCCGCTTAACTCTAAATATGCGAGTTATCGTTATAAAATTTTAGAATCTATCAA
CGATCGTACTCCTTCTGATTTGGAAGATTTTAAATCCTTATGGAAAAAATTTTACGGCGGTACGATCAGTTTAAAATTCA
GAGGTGTAAACCTTCCTATCATTTTAGATCAAGATACGATCGATAAAATCAATATTCGTATTAAAAAACGCTTCGACGTG
GAGGCGGACGAATGA

Upstream 100 bases:

>100_bases
ACGGATCAGATTCAAGAAGGCTCTAAATATCTAGGCAAATTAAAAATTCAATCCATAGAAGCGGATAAAATCCTCTGGCA
TCAGGAAGCGGAAATCTACA

Downstream 100 bases:

>100_bases
AATTTTATTTTTTCAAAATCTTCGTTTTAGTCCTATGTAGTTTGACAATTTCGGTTCCTTTAAAAGCAGAAACGATTCTG
GTTCACTTTAGAAAATTCTC

Product: serine protease

Products: NA

Alternate protein names: HtrA2 Peptidase; 2-Alkenal Reductase; Serine Protease; Trypsin-Like Serine Protease; Trypsin-Like Serine Protease With C-Terminal Pdz Domain; Trypsin Domain Protein; Serine-Type Endopeptidase; Protease Do Subfamily; Pdz/Dhr/Glgf; Protease; Protease Do

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSKKVFLNILILLSIFQLSAQNGNTADLKVLLDGVVIIRSDTFSEKEDQDNYSEKSILRDAGTGMIISGNRILTNAHVVS
NSSYLKVKHFNSSKFYKAEVQYLGFDCDLAILKVEEDEFFSGVEPLEISEVSPALGSNLLILGYPGGDENITLENGNVSR
VERVRYSFSGLDYRKAIRVNANIIPGYSGGPAIQNGRVVGITFQVSQSQGNVAYLIPPEIINHFLKDVEDGTYHGFPFPG
FSFQNGHSSSLKSYLKIPEGLNGILINTIYPDSSFSDLLQPEDFVYKIDNSYLDGDGGIMDEIGGFIGDLIEEKFIGDHI
KLFFYRNGKNYKVEGTLKRVPTLDIYRQQNKSSSFLSGGFLFQPVNRALAGGDSKRLESSLRYHYSYYIQDELYRFTDRD
ILLSGIYPDPLNSKYASYRYKILESINDRTPSDLEDFKSLWKKFYGGTISLKFRGVNLPIILDQDTIDKINIRIKKRFDV
EADE

Sequences:

>Translated_484_residues
MSKKVFLNILILLSIFQLSAQNGNTADLKVLLDGVVIIRSDTFSEKEDQDNYSEKSILRDAGTGMIISGNRILTNAHVVS
NSSYLKVKHFNSSKFYKAEVQYLGFDCDLAILKVEEDEFFSGVEPLEISEVSPALGSNLLILGYPGGDENITLENGNVSR
VERVRYSFSGLDYRKAIRVNANIIPGYSGGPAIQNGRVVGITFQVSQSQGNVAYLIPPEIINHFLKDVEDGTYHGFPFPG
FSFQNGHSSSLKSYLKIPEGLNGILINTIYPDSSFSDLLQPEDFVYKIDNSYLDGDGGIMDEIGGFIGDLIEEKFIGDHI
KLFFYRNGKNYKVEGTLKRVPTLDIYRQQNKSSSFLSGGFLFQPVNRALAGGDSKRLESSLRYHYSYYIQDELYRFTDRD
ILLSGIYPDPLNSKYASYRYKILESINDRTPSDLEDFKSLWKKFYGGTISLKFRGVNLPIILDQDTIDKINIRIKKRFDV
EADE
>Mature_483_residues
SKKVFLNILILLSIFQLSAQNGNTADLKVLLDGVVIIRSDTFSEKEDQDNYSEKSILRDAGTGMIISGNRILTNAHVVSN
SSYLKVKHFNSSKFYKAEVQYLGFDCDLAILKVEEDEFFSGVEPLEISEVSPALGSNLLILGYPGGDENITLENGNVSRV
ERVRYSFSGLDYRKAIRVNANIIPGYSGGPAIQNGRVVGITFQVSQSQGNVAYLIPPEIINHFLKDVEDGTYHGFPFPGF
SFQNGHSSSLKSYLKIPEGLNGILINTIYPDSSFSDLLQPEDFVYKIDNSYLDGDGGIMDEIGGFIGDLIEEKFIGDHIK
LFFYRNGKNYKVEGTLKRVPTLDIYRQQNKSSSFLSGGFLFQPVNRALAGGDSKRLESSLRYHYSYYIQDELYRFTDRDI
LLSGIYPDPLNSKYASYRYKILESINDRTPSDLEDFKSLWKKFYGGTISLKFRGVNLPIILDQDTIDKINIRIKKRFDVE
ADE

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.4.21.- [C]

Molecular weight: Translated: 54538; Mature: 54407

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKVFLNILILLSIFQLSAQNGNTADLKVLLDGVVIIRSDTFSEKEDQDNYSEKSILRD
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCCCCCCCCCCCHHHHHHHH
AGTGMIISGNRILTNAHVVSNSSYLKVKHFNSSKFYKAEVQYLGFDCDLAILKVEEDEFF
CCCCEEEECCEEEEEEEEECCCCEEEEEECCCCCEEEEEEEEEEECCCEEEEEEECHHHH
SGVEPLEISEVSPALGSNLLILGYPGGDENITLENGNVSRVERVRYSFSGLDYRKAIRVN
CCCCCEEECCCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEEEE
ANIIPGYSGGPAIQNGRVVGITFQVSQSQGNVAYLIPPEIINHFLKDVEDGTYHGFPFPG
CEEECCCCCCCCCCCCEEEEEEEEEECCCCCEEEEECHHHHHHHHHHCCCCCCCCCCCCC
FSFQNGHSSSLKSYLKIPEGLNGILINTIYPDSSFSDLLQPEDFVYKIDNSYLDGDGGIM
CCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHCCCCCEEEEECCCEECCCCCHH
DEIGGFIGDLIEEKFIGDHIKLFFYRNGKNYKVEGTLKRVPTLDIYRQQNKSSSFLSGGF
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEHHCCCCEEEHHHCCCCCCCEECCCE
LFQPVNRALAGGDSKRLESSLRYHYSYYIQDELYRFTDRDILLSGIYPDPLNSKYASYRY
EEHHHHHHHCCCCHHHHHHHHEEEEEEEEEHHHHHCCCCEEEEECCCCCCCCCCHHHHHH
KILESINDRTPSDLEDFKSLWKKFYGGTISLKFRGVNLPIILDQDTIDKINIRIKKRFDV
HHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCCCEEEEEEEEEECC
EADE
CCCC
>Mature Secondary Structure 
SKKVFLNILILLSIFQLSAQNGNTADLKVLLDGVVIIRSDTFSEKEDQDNYSEKSILRD
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCCCCCCCCCCCHHHHHHHH
AGTGMIISGNRILTNAHVVSNSSYLKVKHFNSSKFYKAEVQYLGFDCDLAILKVEEDEFF
CCCCEEEECCEEEEEEEEECCCCEEEEEECCCCCEEEEEEEEEEECCCEEEEEEECHHHH
SGVEPLEISEVSPALGSNLLILGYPGGDENITLENGNVSRVERVRYSFSGLDYRKAIRVN
CCCCCEEECCCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEEEE
ANIIPGYSGGPAIQNGRVVGITFQVSQSQGNVAYLIPPEIINHFLKDVEDGTYHGFPFPG
CEEECCCCCCCCCCCCEEEEEEEEEECCCCCEEEEECHHHHHHHHHHCCCCCCCCCCCCC
FSFQNGHSSSLKSYLKIPEGLNGILINTIYPDSSFSDLLQPEDFVYKIDNSYLDGDGGIM
CCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHCCCCCEEEEECCCEECCCCCHH
DEIGGFIGDLIEEKFIGDHIKLFFYRNGKNYKVEGTLKRVPTLDIYRQQNKSSSFLSGGF
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEHHCCCCEEEHHHCCCCCCCEECCCE
LFQPVNRALAGGDSKRLESSLRYHYSYYIQDELYRFTDRDILLSGIYPDPLNSKYASYRY
EEHHHHHHHCCCCHHHHHHHHEEEEEEEEEHHHHHCCCCEEEEECCCCCCCCCCHHHHHH
KILESINDRTPSDLEDFKSLWKKFYGGTISLKFRGVNLPIILDQDTIDKINIRIKKRFDV
HHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCCCEEEEEEEEEECC
EADE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA