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The map label for this gene is insF1 [C]

Identifier: 45656868

GI number: 45656868

Start: 1186497

End: 1187342

Strand: Reverse

Name: insF1 [C]

Synonym: LIC10980

Alternate gene names: 45656868

Gene position: 1187342-1186497 (Counterclockwise)

Preceding gene: 45656869

Following gene: 45656867

Centisome position: 27.76

GC content: 39.01

Gene sequence:

>846_bases
TTGAAGTTCATGAAATCGAATTGCTTAGAGCATAGTATAGGGAGCATGGCAAGAGTTTTAGGAGTATCTCGATCAGGATA
TTATAAATATCTAAACCGTCATAAAGATCGGTCAGTTGCTCCTGAACTTACGAACTTTCTCCAAGAGAAGTGGCTTAAGA
GTCGTAAGAATTACGGTTTTAAACGTCTCTTTCAGGAAGTGAAAAAGTCGAATCTTCCCTATGGAGCGAGGAAAGTTCGA
AAAGCGATGAAACACTGTAAAATTAGCGGGAAACAGAGGAAGCAGTTTAGACCTTTGACAACGAATTCAAAACACGGAGG
TAGAATTGCTCCTGATTTAGTTCAAAGGAAATTTCATCCGAACGAGCAGAACCGAATTTGGGTGTCTGATGTTACATTCA
TTCGGACTTCGTTTGGTTGGAGTTATCTCTGTGTGATCCTGGATTTGTATTCACGCAAGACAGTGGGTTGGTCGCTTTCC
AATCGTAATGATTCTCAGCTGGTATGTGATACGGTATTAAAAGCAGTGTTGTCAAGAAACCCTCGGAAAGGATTGATCTT
TCATTCGGATCGGGGTTCTAATTTCTGTTCTAAAGAAACACGCAGACTACTAATTGCCAACGGTATCAGACGAAGCAACA
GCAGAAAAGGAAATTGTTGGGACAATGCGGTGGCAGAGTCTTTCTTTAGTTCTGTAAAAAGAGAAATCGAATACAATACA
TTCTATAACATTGAAGAAGCGGAACATCTTCTATTCGATTTTATCGAAGTGTATTACAATAGATTCAGGTTTCATTCTAC
ATTAGGTTATATCAGCCCTGAAGAATTTGAGACAAATATTGCTTAA

Upstream 100 bases:

>100_bases
AAGAGTTGAAAAGACTTCGTAAAGAGAATCTGAGATTAAAGGATGAGAACGCGATCTTAAAAAAGTTTGCGGCCATGCTT
TCCCGCGAACAGAATCCCGA

Downstream 100 bases:

>100_bases
ATGGCTGTCCACTTTTATGTGACTACTTCAAATCGACAGTTTCCATACAACGGAAATCGATGGCGAATTAATTTTTCAAC
AACTCTAATATTAAAAACGT

Product: transposase, IS1501

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKFMKSNCLEHSIGSMARVLGVSRSGYYKYLNRHKDRSVAPELTNFLQEKWLKSRKNYGFKRLFQEVKKSNLPYGARKVR
KAMKHCKISGKQRKQFRPLTTNSKHGGRIAPDLVQRKFHPNEQNRIWVSDVTFIRTSFGWSYLCVILDLYSRKTVGWSLS
NRNDSQLVCDTVLKAVLSRNPRKGLIFHSDRGSNFCSKETRRLLIANGIRRSNSRKGNCWDNAVAESFFSSVKREIEYNT
FYNIEEAEHLLFDFIEVYYNRFRFHSTLGYISPEEFETNIA

Sequences:

>Translated_281_residues
MKFMKSNCLEHSIGSMARVLGVSRSGYYKYLNRHKDRSVAPELTNFLQEKWLKSRKNYGFKRLFQEVKKSNLPYGARKVR
KAMKHCKISGKQRKQFRPLTTNSKHGGRIAPDLVQRKFHPNEQNRIWVSDVTFIRTSFGWSYLCVILDLYSRKTVGWSLS
NRNDSQLVCDTVLKAVLSRNPRKGLIFHSDRGSNFCSKETRRLLIANGIRRSNSRKGNCWDNAVAESFFSSVKREIEYNT
FYNIEEAEHLLFDFIEVYYNRFRFHSTLGYISPEEFETNIA
>Mature_281_residues
MKFMKSNCLEHSIGSMARVLGVSRSGYYKYLNRHKDRSVAPELTNFLQEKWLKSRKNYGFKRLFQEVKKSNLPYGARKVR
KAMKHCKISGKQRKQFRPLTTNSKHGGRIAPDLVQRKFHPNEQNRIWVSDVTFIRTSFGWSYLCVILDLYSRKTVGWSLS
NRNDSQLVCDTVLKAVLSRNPRKGLIFHSDRGSNFCSKETRRLLIANGIRRSNSRKGNCWDNAVAESFFSSVKREIEYNT
FYNIEEAEHLLFDFIEVYYNRFRFHSTLGYISPEEFETNIA

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=262, Percent_Identity=30.5343511450382, Blast_Score=121, Evalue=7e-28,
Organism=Escherichia coli, GI1788405, Length=280, Percent_Identity=35, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1787263, Length=280, Percent_Identity=35, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1786753, Length=280, Percent_Identity=35, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1786570, Length=280, Percent_Identity=35, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1786490, Length=280, Percent_Identity=35, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1789981, Length=268, Percent_Identity=27.9850746268657, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33012; Mature: 33012

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure
MKFMKSNCLEHSIGSMARVLGVSRSGYYKYLNRHKDRSVAPELTNFLQEKWLKSRKNYGF
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCH
KRLFQEVKKSNLPYGARKVRKAMKHCKISGKQRKQFRPLTTNSKHGGRIAPDLVQRKFHP
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHCCC
NEQNRIWVSDVTFIRTSFGWSYLCVILDLYSRKTVGWSLSNRNDSQLVCDTVLKAVLSRN
CCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
PRKGLIFHSDRGSNFCSKETRRLLIANGIRRSNSRKGNCWDNAVAESFFSSVKREIEYNT
CCCCEEEECCCCCCHHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
FYNIEEAEHLLFDFIEVYYNRFRFHSTLGYISPEEFETNIA
EECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]