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The map label for this gene is rfe

Identifier: 45656732

GI number: 45656732

Start: 1020492

End: 1021406

Strand: Reverse

Name: rfe

Synonym: LIC10841

Alternate gene names: 45656732

Gene position: 1021406-1020492 (Counterclockwise)

Preceding gene: 45656752

Following gene: 45656722

Centisome position: 23.88

GC content: 36.28

Gene sequence:

>915_bases
ATGCACGTAGGTACGACCAAAAAATCAGGAGGAATTTGGATTTTACTTCCTATTTTTTGTTTGGCAATCGTCTGGTTCAG
TGTTTTTGAAATTCCCGATCGTAAAATTTTTCTATTTTTTACGGGTTTGTTTTTCTTTTTTTTGATCGGTCTTGCGGACG
ATCTTCTCTCATTGAGTGCTGGAATTCGTCTCGTTTTGGAAATTTTTTTCCTAATCGTTTTCTTTTATCTGGAACCGGTT
CGATTTTCATTTCTAAGTTTAAGTATAGAAAACATCCCAGGCCTTTCCACTTTGATTTTGATCGTCTACGTTTTGTTTGT
TGTTAACGTTTGTAATTTTATGGACGGTCTAGACGCGTATCTTTCTTCTCATTTCCTCTTTGCCATTTTAGCGTTTCCAT
TTTTATTTCATTCTCATCTTCCTTTATTTTATTCTTGGATCTGCGCAGGTGTTTTCGGTTTTTTAGGTTTTAACTTACCT
AAGGCAAAACTTTTTTTAGGTGATTCCGGTTCGCTTCCTCTCGGTTATACAATTTCTGTTCTTCCTTTGTTTTTTATAGA
TGGTAAACTTTGGGGTTCATTTGAAATCTCTTCCGCATTCTTTTTGTTGCCAGTGTTTTTTGTGGACGGTGTAGTTACGA
TTTTTTTGCGGCTGAAAGACGGAGAAAATATTTTCCAAGCTCATCGTAGACATCTTTATCAGCTAATCGCTGTTAGCTCT
AAAAATAAAGGTTTAGTTTCGTTTCTTTTTACGATCGCCAATCTTCCGGCTATGATCCTATTTTCGTTTCATCGTAACCT
CAAAATTCCCGGCAGTATTATTTTTTGGATCTGCTTGGTATTTTATGTAGGCGTGTATTTTTTATTGTTTCGTAAATTTA
GAACGCCTAGCCCAAATCCCGTCGAGCGCCAATAG

Upstream 100 bases:

>100_bases
ATTTACGTGTGCTCTCATTTTTTTTGCCACGTCATTTTTCTCTTGGATTTATCTTCATTCCAAAAGGTTCACAATCTCGG
ACGTCTCAAATGAAAGAAGT

Downstream 100 bases:

>100_bases
AAGCGAGACGCTGAGTTTCTTCGAGCGCCAATAGAAGCGAGACGCTTTTATTTCACAAAAATGTGGAAACTCATATAGAA
GTTATACAATCTTAGAAGTT

Product: undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: Glycosyl Transferase Family 4 Conserved Region; Family 4 Glycosyl Transferase; Glycosyl Transferase Family Protein; Sugar Phosphotransferase; Phospho-N-Acetylmuramoyl-Pentapeptide-Transferase; O-Antigen Initiating Glycosyl Transferase

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MHVGTTKKSGGIWILLPIFCLAIVWFSVFEIPDRKIFLFFTGLFFFFLIGLADDLLSLSAGIRLVLEIFFLIVFFYLEPV
RFSFLSLSIENIPGLSTLILIVYVLFVVNVCNFMDGLDAYLSSHFLFAILAFPFLFHSHLPLFYSWICAGVFGFLGFNLP
KAKLFLGDSGSLPLGYTISVLPLFFIDGKLWGSFEISSAFFLLPVFFVDGVVTIFLRLKDGENIFQAHRRHLYQLIAVSS
KNKGLVSFLFTIANLPAMILFSFHRNLKIPGSIIFWICLVFYVGVYFLLFRKFRTPSPNPVERQ

Sequences:

>Translated_304_residues
MHVGTTKKSGGIWILLPIFCLAIVWFSVFEIPDRKIFLFFTGLFFFFLIGLADDLLSLSAGIRLVLEIFFLIVFFYLEPV
RFSFLSLSIENIPGLSTLILIVYVLFVVNVCNFMDGLDAYLSSHFLFAILAFPFLFHSHLPLFYSWICAGVFGFLGFNLP
KAKLFLGDSGSLPLGYTISVLPLFFIDGKLWGSFEISSAFFLLPVFFVDGVVTIFLRLKDGENIFQAHRRHLYQLIAVSS
KNKGLVSFLFTIANLPAMILFSFHRNLKIPGSIIFWICLVFYVGVYFLLFRKFRTPSPNPVERQ
>Mature_304_residues
MHVGTTKKSGGIWILLPIFCLAIVWFSVFEIPDRKIFLFFTGLFFFFLIGLADDLLSLSAGIRLVLEIFFLIVFFYLEPV
RFSFLSLSIENIPGLSTLILIVYVLFVVNVCNFMDGLDAYLSSHFLFAILAFPFLFHSHLPLFYSWICAGVFGFLGFNLP
KAKLFLGDSGSLPLGYTISVLPLFFIDGKLWGSFEISSAFFLLPVFFVDGVVTIFLRLKDGENIFQAHRRHLYQLIAVSS
KNKGLVSFLFTIANLPAMILFSFHRNLKIPGSIIFWICLVFYVGVYFLLFRKFRTPSPNPVERQ

Specific function: Catalyzes The Synthesis Of Und-Pp-Glcnac (Lipid I), The First Lipid-Linked Intermediate Involved In Eca Synthesis. This Lipid Is Also An Acceptor For The Addition Of Subsequent Sugars To Complete The Biosynthesis Of O-Antigen. [C]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.8.- [C]

Molecular weight: Translated: 34698; Mature: 34698

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVGTTKKSGGIWILLPIFCLAIVWFSVFEIPDRKIFLFFTGLFFFFLIGLADDLLSLSA
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GIRLVLEIFFLIVFFYLEPVRFSFLSLSIENIPGLSTLILIVYVLFVVNVCNFMDGLDAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSHFLFAILAFPFLFHSHLPLFYSWICAGVFGFLGFNLPKAKLFLGDSGSLPLGYTISV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHH
LPLFFIDGKLWGSFEISSAFFLLPVFFVDGVVTIFLRLKDGENIFQAHRRHLYQLIAVSS
HHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
KNKGLVSFLFTIANLPAMILFSFHRNLKIPGSIIFWICLVFYVGVYFLLFRKFRTPSPNP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VERQ
CCCC
>Mature Secondary Structure
MHVGTTKKSGGIWILLPIFCLAIVWFSVFEIPDRKIFLFFTGLFFFFLIGLADDLLSLSA
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GIRLVLEIFFLIVFFYLEPVRFSFLSLSIENIPGLSTLILIVYVLFVVNVCNFMDGLDAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSHFLFAILAFPFLFHSHLPLFYSWICAGVFGFLGFNLPKAKLFLGDSGSLPLGYTISV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHH
LPLFFIDGKLWGSFEISSAFFLLPVFFVDGVVTIFLRLKDGENIFQAHRRHLYQLIAVSS
HHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
KNKGLVSFLFTIANLPAMILFSFHRNLKIPGSIIFWICLVFYVGVYFLLFRKFRTPSPNP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VERQ
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA