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The map label for this gene is thiL

Identifier: 45656653

GI number: 45656653

Start: 923278

End: 924201

Strand: Reverse

Name: thiL

Synonym: LIC10759

Alternate gene names: 45656653

Gene position: 924201-923278 (Counterclockwise)

Preceding gene: 45656660

Following gene: 45656652

Centisome position: 21.61

GC content: 39.18

Gene sequence:

>924_bases
TTGAAGGAAAATTTAATTTTGAAAGAATCGGAAGTCATTCGTATCCTTTATCCACCTGGAATCGTTCAGACTGACGACTG
TTATCTGGACGAAGAAGGTCGGATCTACACAACCGATACGATCTGCGAAGGGACACATTTTAGAATCGAGTGGAGTGGTC
CTAAAGAAATCGCTCAAAAACTCGTGGAAGTAAACGTCTCCGATATAGCTGCAGGAGGTGGAATTCCTACCAAAGCTTTT
TTAAACCTCGGTCTTAGTACACAGTGTTCTAAAGAAGAATGGATCCTTCCTTTCTCTATTTCATTACAAGAATCTCTATC
TTCCTATAACATAGAACTTTGTGGTGGAGACACGTATCGTTCTTCTTCTCTCAATCTAACTCTTACCTTGATCGGTGTAA
CTACCAAACCTTGGAAACGTTCCGGTGGAAAAGATGGAGACTTTCTTTATCTCACAGGTTCAGTTGGTCTTTCTTTGCTT
GGATATAAAATATTGAAGGAGGGTCTAGATATTCCGGAACCACTTCGAAGTCTAGCTTTGGAAAGGCACCTCACACCTAA
AGCACGATTGAAAGTTTCAAAAGAACTTTCAAAAAATTCTCCCGTTTCCTGTTGTATGGATCTAACCGACGGACTTTTAT
TGGATCTTCCAAAGTTAGCATCTTCTTCAAATCTTGGACTAAAAATCGATCTGGAAAAAATTCCAATCCTTTCTAATATT
CTCACCTACTTAAGTTTAGGCGAAGTCCTATCTTCCGGCGAAGAGCTAGAACTTATCTTTTTAAGTCCGGTTGAACTACC
AAAAACATTATGCGAAACATCCTTGACCAAAATCGGAAATACAACATCGGATTGGAAAGGTGTGAAGTTTTTCCAAGGAA
ACTCAGAAAAAACCTTTGAGCATCTAGGGTTTGAACATTTTTGA

Upstream 100 bases:

>100_bases
GAAAATCCAGCGACAAAAGGAAGTAAGGTCAAACAATAGAATAGAATGATTCGTTTCATAGTCTCTCAGACTGACTTGAA
AACGAAGAAAGTCAAGATTT

Downstream 100 bases:

>100_bases
GTTTTTAAAATAACATGAGCTTGGGCTAAAGAGAGGGTAAAAGTTGAAAATTGTTTTTGGAAAAAAGGAAAATACAACTA
AACCCTTAATAGATCAACGA

Product: thiamine-monophosphate kinase protein

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKENLILKESEVIRILYPPGIVQTDDCYLDEEGRIYTTDTICEGTHFRIEWSGPKEIAQKLVEVNVSDIAAGGGIPTKAF
LNLGLSTQCSKEEWILPFSISLQESLSSYNIELCGGDTYRSSSLNLTLTLIGVTTKPWKRSGGKDGDFLYLTGSVGLSLL
GYKILKEGLDIPEPLRSLALERHLTPKARLKVSKELSKNSPVSCCMDLTDGLLLDLPKLASSSNLGLKIDLEKIPILSNI
LTYLSLGEVLSSGEELELIFLSPVELPKTLCETSLTKIGNTTSDWKGVKFFQGNSEKTFEHLGFEHF

Sequences:

>Translated_307_residues
MKENLILKESEVIRILYPPGIVQTDDCYLDEEGRIYTTDTICEGTHFRIEWSGPKEIAQKLVEVNVSDIAAGGGIPTKAF
LNLGLSTQCSKEEWILPFSISLQESLSSYNIELCGGDTYRSSSLNLTLTLIGVTTKPWKRSGGKDGDFLYLTGSVGLSLL
GYKILKEGLDIPEPLRSLALERHLTPKARLKVSKELSKNSPVSCCMDLTDGLLLDLPKLASSSNLGLKIDLEKIPILSNI
LTYLSLGEVLSSGEELELIFLSPVELPKTLCETSLTKIGNTTSDWKGVKFFQGNSEKTFEHLGFEHF
>Mature_307_residues
MKENLILKESEVIRILYPPGIVQTDDCYLDEEGRIYTTDTICEGTHFRIEWSGPKEIAQKLVEVNVSDIAAGGGIPTKAF
LNLGLSTQCSKEEWILPFSISLQESLSSYNIELCGGDTYRSSSLNLTLTLIGVTTKPWKRSGGKDGDFLYLTGSVGLSLL
GYKILKEGLDIPEPLRSLALERHLTPKARLKVSKELSKNSPVSCCMDLTDGLLLDLPKLASSSNLGLKIDLEKIPILSNI
LTYLSLGEVLSSGEELELIFLSPVELPKTLCETSLTKIGNTTSDWKGVKFFQGNSEKTFEHLGFEHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=301, Percent_Identity=33.2225913621262, Blast_Score=134, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 33838; Mature: 33838

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKENLILKESEVIRILYPPGIVQTDDCYLDEEGRIYTTDTICEGTHFRIEWSGPKEIAQK
CCCCEEEECCCEEEEEECCCCEECCCCEECCCCCEEEECEEECCCEEEEEECCHHHHHHH
LVEVNVSDIAAGGGIPTKAFLNLGLSTQCSKEEWILPFSISLQESLSSYNIELCGGDTYR
HHHCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHCEEEEECCCCCC
SSSLNLTLTLIGVTTKPWKRSGGKDGDFLYLTGSVGLSLLGYKILKEGLDIPEPLRSLAL
CCCCEEEEEEEEECCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHH
ERHLTPKARLKVSKELSKNSPVSCCMDLTDGLLLDLPKLASSSNLGLKIDLEKIPILSNI
HHCCCCHHHHHHHHHHCCCCCCEEEHHHCCCHHEECHHHCCCCCCCEEEEHHHCCHHHHH
LTYLSLGEVLSSGEELELIFLSPVELPKTLCETSLTKIGNTTSDWKGVKFFQGNSEKTFE
HHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHH
HLGFEHF
HCCCCCC
>Mature Secondary Structure
MKENLILKESEVIRILYPPGIVQTDDCYLDEEGRIYTTDTICEGTHFRIEWSGPKEIAQK
CCCCEEEECCCEEEEEECCCCEECCCCEECCCCCEEEECEEECCCEEEEEECCHHHHHHH
LVEVNVSDIAAGGGIPTKAFLNLGLSTQCSKEEWILPFSISLQESLSSYNIELCGGDTYR
HHHCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHCEEEEECCCCCC
SSSLNLTLTLIGVTTKPWKRSGGKDGDFLYLTGSVGLSLLGYKILKEGLDIPEPLRSLAL
CCCCEEEEEEEEECCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHH
ERHLTPKARLKVSKELSKNSPVSCCMDLTDGLLLDLPKLASSSNLGLKIDLEKIPILSNI
HHCCCCHHHHHHHHHHCCCCCCEEEHHHCCCHHEECHHHCCCCCCCEEEEHHHCCHHHHH
LTYLSLGEVLSSGEELELIFLSPVELPKTLCETSLTKIGNTTSDWKGVKFFQGNSEKTFE
HHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHH
HLGFEHF
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]