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The map label for this gene is glcD [H]

Identifier: 45656616

GI number: 45656616

Start: 872171

End: 873616

Strand: Reverse

Name: glcD [H]

Synonym: LIC10718

Alternate gene names: 45656616

Gene position: 873616-872171 (Counterclockwise)

Preceding gene: 45656617

Following gene: 45656615

Centisome position: 20.43

GC content: 37.62

Gene sequence:

>1446_bases
TTGCGGAATAAAACTTTAAAAATGAGTATGACTACAAATTTTACAATCAACAAATCCGAACTTAAATCCCTTATTGGACC
CGGAAAAATATTTTTCAGAGACGATCCAGAGTTTGACGAAACTACCTTTCTTTCTTTCGGAACGGATAGAACCAAGGTCT
ACCAACCAGACTTCAATATTCTCGCCTTTCCTACAACAACGGAGGAAGTTGCAAAAATTATAAAATACGCATACGAAAAC
GAAATTTCAATCGTTCCTTCTGGAGGAAGAACCGGATACGCAGGCGGAGCGATCGCCAAAAACAAGGAATTAGTGCTTTC
TCTTTCCAAAATGGACAAGGTTTTAGACTTTGATCCTTTTTTTGGAAGTATCAAAGTACAGGCGGGAATGATCACTAAAA
ATCTTCACAAAGAAGCGGAAGAAAAAAATTTCTATTTTCCGGTAGATTTTGCATCGACAGGCTCTTCTCAAATCGGAGGA
AACATAGCGACTAACGCAGGTGGCGTTAGGGTCGTTCATTACGGATTGATTCGCCAATGGGTTTTAGGACTTACGGTAGT
TACCGGAACTGGAGAAATTTTAGAGTTTAACGGAGAAGTTCTCAAAAACAATACCGGATACGATCTTAAACAACTATTTA
TCGGCTCAGAAGGAACGTTAGGCGTCATTACGGAAGCAACTCTTAAATTGACCACAAAACCTCTGGATAGTCGGGTTTTA
CTCGTCGCGGTTTCTGATTTCGCATCTATTCTTTCCTTATTTCAAGAAACTCATCTTGTCAAAGTTCCACTACTCGCGTT
TGAATTTTTTACGGAATACTGTCTCGGAAAAGTTAAATCTCACCTTGGAATTCCAGATCCGTTTCAATCTCCAAGTCCAT
ATTACGTTTTAATGGAATTTGAAATTGCAGACGAATCCGACGACGAAAAACTATTCGGTTTTTTGGAAACGATTACGGAA
AAGGGTCTGATCGTAGACGGAAGCCTAGCACAGAATTCAAGACAATCCGAAACTTTTTGGAAATATAGAGAAGGGATCAG
CGAAAGTATTTCTATAGAATATACGGTTCATAAAAATGATATCTCTCTTCCTTTGAGAAACATGGAACCGTTTCTTGTAG
ACATGAAATCGCTGTTAAACGGAAAATATCCAGGATTCGAAATTGCTCTTTTTGGTCATGTAGGAGACGGGAATCTTCAT
TTAAACATAATAAAACCGAAAGATCTTTCTAACGAAGATTTTTTTAAAAAATGTAAGGAAGTGGACCCGGATATGTTTCG
TTTATTACAAAAATATCATGGATCGATCAGCGCCGAACACGGAATCGGTCTTTTAAAAAAAGACTTTCTCCATTTTTCCA
GAACACAAGCTGAAATCATTTTGATGAAAGAAATTAAAAAATCAATGGATCCTAAAAACATCATGAATCCGGGCAAAGTA
TTCTAA

Upstream 100 bases:

>100_bases
AACGTAAAAGCTCGGTTTTTGCGCCCAGACGGACATTACGTAAAGAAAATATTAGAAAAAGATGAAAAACCCGTAGATTC
TCAAATCGAAAGAATGACAT

Downstream 100 bases:

>100_bases
TGATTTCCCCGAACGGCTCCAGCGGCAAAAAACCAAGTAAAAGAAAAAAGAAAATACAATCCGAACATAGAATTGTTATG
CGAAGTCTCACTTTAGACGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MRNKTLKMSMTTNFTINKSELKSLIGPGKIFFRDDPEFDETTFLSFGTDRTKVYQPDFNILAFPTTTEEVAKIIKYAYEN
EISIVPSGGRTGYAGGAIAKNKELVLSLSKMDKVLDFDPFFGSIKVQAGMITKNLHKEAEEKNFYFPVDFASTGSSQIGG
NIATNAGGVRVVHYGLIRQWVLGLTVVTGTGEILEFNGEVLKNNTGYDLKQLFIGSEGTLGVITEATLKLTTKPLDSRVL
LVAVSDFASILSLFQETHLVKVPLLAFEFFTEYCLGKVKSHLGIPDPFQSPSPYYVLMEFEIADESDDEKLFGFLETITE
KGLIVDGSLAQNSRQSETFWKYREGISESISIEYTVHKNDISLPLRNMEPFLVDMKSLLNGKYPGFEIALFGHVGDGNLH
LNIIKPKDLSNEDFFKKCKEVDPDMFRLLQKYHGSISAEHGIGLLKKDFLHFSRTQAEIILMKEIKKSMDPKNIMNPGKV
F

Sequences:

>Translated_481_residues
MRNKTLKMSMTTNFTINKSELKSLIGPGKIFFRDDPEFDETTFLSFGTDRTKVYQPDFNILAFPTTTEEVAKIIKYAYEN
EISIVPSGGRTGYAGGAIAKNKELVLSLSKMDKVLDFDPFFGSIKVQAGMITKNLHKEAEEKNFYFPVDFASTGSSQIGG
NIATNAGGVRVVHYGLIRQWVLGLTVVTGTGEILEFNGEVLKNNTGYDLKQLFIGSEGTLGVITEATLKLTTKPLDSRVL
LVAVSDFASILSLFQETHLVKVPLLAFEFFTEYCLGKVKSHLGIPDPFQSPSPYYVLMEFEIADESDDEKLFGFLETITE
KGLIVDGSLAQNSRQSETFWKYREGISESISIEYTVHKNDISLPLRNMEPFLVDMKSLLNGKYPGFEIALFGHVGDGNLH
LNIIKPKDLSNEDFFKKCKEVDPDMFRLLQKYHGSISAEHGIGLLKKDFLHFSRTQAEIILMKEIKKSMDPKNIMNPGKV
F
>Mature_481_residues
MRNKTLKMSMTTNFTINKSELKSLIGPGKIFFRDDPEFDETTFLSFGTDRTKVYQPDFNILAFPTTTEEVAKIIKYAYEN
EISIVPSGGRTGYAGGAIAKNKELVLSLSKMDKVLDFDPFFGSIKVQAGMITKNLHKEAEEKNFYFPVDFASTGSSQIGG
NIATNAGGVRVVHYGLIRQWVLGLTVVTGTGEILEFNGEVLKNNTGYDLKQLFIGSEGTLGVITEATLKLTTKPLDSRVL
LVAVSDFASILSLFQETHLVKVPLLAFEFFTEYCLGKVKSHLGIPDPFQSPSPYYVLMEFEIADESDDEKLFGFLETITE
KGLIVDGSLAQNSRQSETFWKYREGISESISIEYTVHKNDISLPLRNMEPFLVDMKSLLNGKYPGFEIALFGHVGDGNLH
LNIIKPKDLSNEDFFKKCKEVDPDMFRLLQKYHGSISAEHGIGLLKKDFLHFSRTQAEIILMKEIKKSMDPKNIMNPGKV
F

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=472, Percent_Identity=36.4406779661017, Blast_Score=306, Evalue=3e-83,
Organism=Homo sapiens, GI37595756, Length=439, Percent_Identity=28.246013667426, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI37595754, Length=455, Percent_Identity=26.8131868131868, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI4501993, Length=202, Percent_Identity=30.6930693069307, Blast_Score=93, Evalue=7e-19,
Organism=Escherichia coli, GI1789351, Length=447, Percent_Identity=28.6353467561521, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1787977, Length=523, Percent_Identity=24.0917782026769, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI48994914, Length=158, Percent_Identity=31.6455696202532, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI48994907, Length=221, Percent_Identity=26.2443438914027, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17534361, Length=439, Percent_Identity=34.8519362186788, Blast_Score=265, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI71992373, Length=473, Percent_Identity=27.906976744186, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI71992381, Length=473, Percent_Identity=27.2727272727273, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI71992392, Length=381, Percent_Identity=28.3464566929134, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17556096, Length=208, Percent_Identity=28.3653846153846, Blast_Score=92, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6320023, Length=451, Percent_Identity=36.8070953436807, Blast_Score=291, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6320764, Length=489, Percent_Identity=34.3558282208589, Blast_Score=280, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6320027, Length=439, Percent_Identity=27.3348519362187, Blast_Score=162, Evalue=1e-40,
Organism=Drosophila melanogaster, GI18921117, Length=422, Percent_Identity=37.914691943128, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24639277, Length=422, Percent_Identity=37.914691943128, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24639275, Length=422, Percent_Identity=37.914691943128, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24653753, Length=193, Percent_Identity=27.4611398963731, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 53875; Mature: 53875

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNKTLKMSMTTNFTINKSELKSLIGPGKIFFRDDPEFDETTFLSFGTDRTKVYQPDFNI
CCCCEEEEEEEEEEEECHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCCCEEECCCCCE
LAFPTTTEEVAKIIKYAYENEISIVPSGGRTGYAGGAIAKNKELVLSLSKMDKVLDFDPF
EEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHEEEHHHHHHHHCCCCC
FGSIKVQAGMITKNLHKEAEEKNFYFPVDFASTGSSQIGGNIATNAGGVRVVHYGLIRQW
CCCEEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCEEEEHHHHHHHH
VLGLTVVTGTGEILEFNGEVLKNNTGYDLKQLFIGSEGTLGVITEATLKLTTKPLDSRVL
HHHEEEEECCCCEEEECCEEEECCCCCCHHHEEECCCCCEEEEEEEEEEEEECCCCCEEE
LVAVSDFASILSLFQETHLVKVPLLAFEFFTEYCLGKVKSHLGIPDPFQSPSPYYVLMEF
EEEHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
EIADESDDEKLFGFLETITEKGLIVDGSLAQNSRQSETFWKYREGISESISIEYTVHKND
EECCCCCHHHHHHHHHHHHHCCEEEECHHCCCCCCHHHHHHHHHCCCCCEEEEEEEECCC
ISLPLRNMEPFLVDMKSLLNGKYPGFEIALFGHVGDGNLHLNIIKPKDLSNEDFFKKCKE
CCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHC
VDPDMFRLLQKYHGSISAEHGIGLLKKDFLHFSRTQAEIILMKEIKKSMDPKNIMNPGKV
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHEEEHHHHHHHCCCHHCCCCCCC
F
C
>Mature Secondary Structure
MRNKTLKMSMTTNFTINKSELKSLIGPGKIFFRDDPEFDETTFLSFGTDRTKVYQPDFNI
CCCCEEEEEEEEEEEECHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCCCEEECCCCCE
LAFPTTTEEVAKIIKYAYENEISIVPSGGRTGYAGGAIAKNKELVLSLSKMDKVLDFDPF
EEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHEEEHHHHHHHHCCCCC
FGSIKVQAGMITKNLHKEAEEKNFYFPVDFASTGSSQIGGNIATNAGGVRVVHYGLIRQW
CCCEEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCEEEEHHHHHHHH
VLGLTVVTGTGEILEFNGEVLKNNTGYDLKQLFIGSEGTLGVITEATLKLTTKPLDSRVL
HHHEEEEECCCCEEEECCEEEECCCCCCHHHEEECCCCCEEEEEEEEEEEEECCCCCEEE
LVAVSDFASILSLFQETHLVKVPLLAFEFFTEYCLGKVKSHLGIPDPFQSPSPYYVLMEF
EEEHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
EIADESDDEKLFGFLETITEKGLIVDGSLAQNSRQSETFWKYREGISESISIEYTVHKND
EECCCCCHHHHHHHHHHHHHCCEEEECHHCCCCCCHHHHHHHHHCCCCCEEEEEEEECCC
ISLPLRNMEPFLVDMKSLLNGKYPGFEIALFGHVGDGNLHLNIIKPKDLSNEDFFKKCKE
CCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHC
VDPDMFRLLQKYHGSISAEHGIGLLKKDFLHFSRTQAEIILMKEIKKSMDPKNIMNPGKV
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHEEEHHHHHHHCCCHHCCCCCCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]