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The map label for this gene is sigX [H]

Identifier: 45656542

GI number: 45656542

Start: 786949

End: 787473

Strand: Reverse

Name: sigX [H]

Synonym: LIC10644

Alternate gene names: 45656542

Gene position: 787473-786949 (Counterclockwise)

Preceding gene: 45656543

Following gene: 45656541

Centisome position: 18.41

GC content: 32.19

Gene sequence:

>525_bases
ATGAAATTAAGTCAGGATCACGATTTCTCAGTATTTTATAAAAACTATAAAGATTCTATCTACAAGGTGATTCGATTTCT
TTCCAGCGATCCGGAAGAAGTGGAGGATGTGGCTCAGGAAGTTTTTTTAAATCTATATAAATCCTTTTCGAACTTCTCAC
CGGAAAAAGGTAGTTTTTATACCTGGGCGGCGACGATTGCAAAGAATACTTTTTACACATATAGAAAAAAACAAAAGAAA
GATATGATCGTAGAAGGAGACGCAGTTTTTATAGAATCTCTCCAAGTAGAGGATGATTTTATTCAAAACATAGAATCAAA
AATTGTAGAGGAAGAATTAAGGGAGATTATCTCCTCTTTACCCGAACCTGAAAAGAGTATTATTTTGTTAAAAGAAATCA
ATAATTATACATTAGAAAAAACTTCACAAGCGTTAAACATATCAACAAGAACCGTCAGCAGAAAACTATTAAAAGCGCTG
GATCTACTTAGAGAAGAATTAGAAAGAAGAAAAGTGGTTTTATAA

Upstream 100 bases:

>100_bases
ATTCGGGGCAACTCCTTTTATTTCAATAGGCAAAACCGAATCGAACTTTTTAAGGAATAACTTCCTGAATATGTTTGAAT
TCTTATACAGAGCATAGGTA

Downstream 100 bases:

>100_bases
TTATGGAAAAAAAAGATCTACAAGAAGAGTTTGAAGAACTAATGTCTCTGTTTCTTTTCGGCGGAACAGAATCGGAAGAA
GAAAAAAGATTAAACGAAAT

Product: RNA polymerase ECF-type sigma factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MKLSQDHDFSVFYKNYKDSIYKVIRFLSSDPEEVEDVAQEVFLNLYKSFSNFSPEKGSFYTWAATIAKNTFYTYRKKQKK
DMIVEGDAVFIESLQVEDDFIQNIESKIVEEELREIISSLPEPEKSIILLKEINNYTLEKTSQALNISTRTVSRKLLKAL
DLLREELERRKVVL

Sequences:

>Translated_174_residues
MKLSQDHDFSVFYKNYKDSIYKVIRFLSSDPEEVEDVAQEVFLNLYKSFSNFSPEKGSFYTWAATIAKNTFYTYRKKQKK
DMIVEGDAVFIESLQVEDDFIQNIESKIVEEELREIISSLPEPEKSIILLKEINNYTLEKTSQALNISTRTVSRKLLKAL
DLLREELERRKVVL
>Mature_174_residues
MKLSQDHDFSVFYKNYKDSIYKVIRFLSSDPEEVEDVAQEVFLNLYKSFSNFSPEKGSFYTWAATIAKNTFYTYRKKQKK
DMIVEGDAVFIESLQVEDDFIQNIESKIVEEELREIISSLPEPEKSIILLKEINNYTLEKTSQALNISTRTVSRKLLKAL
DLLREELERRKVVL

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. May be involved in the regulation of iron metabolism [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=163, Percent_Identity=28.2208588957055, Blast_Score=60, Evalue=6e-11,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20453; Mature: 20453

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSQDHDFSVFYKNYKDSIYKVIRFLSSDPEEVEDVAQEVFLNLYKSFSNFSPEKGSFY
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
TWAATIAKNTFYTYRKKQKKDMIVEGDAVFIESLQVEDDFIQNIESKIVEEELREIISSL
HHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
PEPEKSIILLKEINNYTLEKTSQALNISTRTVSRKLLKALDLLREELERRKVVL
CCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLSQDHDFSVFYKNYKDSIYKVIRFLSSDPEEVEDVAQEVFLNLYKSFSNFSPEKGSFY
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
TWAATIAKNTFYTYRKKQKKDMIVEGDAVFIESLQVEDDFIQNIESKIVEEELREIISSL
HHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
PEPEKSIILLKEINNYTLEKTSQALNISTRTVSRKLLKALDLLREELERRKVVL
CCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8052622; 9393439 [H]