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The map label for this gene is ksgA

Identifier: 45656257

GI number: 45656257

Start: 400333

End: 401238

Strand: Reverse

Name: ksgA

Synonym: LIC10354

Alternate gene names: 45656257

Gene position: 401238-400333 (Counterclockwise)

Preceding gene: 45656258

Following gene: 45656253

Centisome position: 9.38

GC content: 35.1

Gene sequence:

>906_bases
ATGAGCTCCAGAGAATACCCATTTCGGAAAGTTTCTGAGATTCGAAAATTCTTGGAGTCAAAATCCTCCGCGCCGTTAAA
AAAATGGGGGCAGAATTTTTTAATCGATCCGAACGCGATTCGATCCATTTTAGATTGTCTGAATTTCGACCTTCTTTCTA
CAATCGATCGAATTTTAGAAATTGGTCCCGGACTGGGCGCAATCTCTCACGGATTACTCGACTTCAAAAAACCAGTAACG
TTATTCGAAATCGATCCCATATATTCAAATTGGCTCAGAGAATATCTTCCAGAATTTGAGCTTAAAGAAGGAAACGCTCT
CGACTTTTTATCCGAATATTCACAAGATTCAACATATCTTTTTGGAAATCTTCCTTACTATATTTCTTCCGAACTTACCT
TAAACTCGGTTAAAAATTTAAAAGGACTGAAAGGCGCTACATTTTTAGTACAAAAAGAATTCGCAAAAAGAATTTCAGCT
GAACCTTCTTCGATTCAATTTTATCTTTCGGCCTACGGAAATTGGAGTTTAAAAAAAGACATAAAGGCCGGGGCTTTTTA
TCCAAAACCAAATGTAGATTCCTCAATTTTAGAATATAAATCTTTACCCGTATTTAAAAACGAATCCGGATTTATTGCAC
TCGAGTGTATTTGTAGAACCGCTTTCTGGGGAAAAAGAAAAAAATTAACTTCGTCTTTTAGAGACGCTCCTATCGAATCT
TTACCTTTGGAAGTTTATTCTTCCGAAAATTTTTCCGAAAAAACATTTCGTACCGAATGTTTAAAAGCTTTAAAGAGTGT
AAACATCGATCTGGACAAAAGACCAGAAGAATTAAAATCGAAAGACTTTCATGAAGCCGCAAAAATTCTTTCGGCCTATA
TATCAGAAATATTGAATATATCTTAA

Upstream 100 bases:

>100_bases
CTTTTAGAAACTCCTTTTGGAAACCAAGAAGATTCGAAAGTATGGAATCGAAACCGAAAACTGCTTGGGCTTACGGAGAG
TTGGGTGTTTCTGGAAAAAG

Downstream 100 bases:

>100_bases
GGAAAGTTTTTATATTCTAGAAGAGTTTTATCCATAAATTCTACAAATTCTTCTTCCTTTTTAAAACCAAAATGCTGAAG
GACCGCAGACTGTATCATAG

Product: dimethyladenosine transferase

Products: NA

Alternate protein names: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase; 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSSREYPFRKVSEIRKFLESKSSAPLKKWGQNFLIDPNAIRSILDCLNFDLLSTIDRILEIGPGLGAISHGLLDFKKPVT
LFEIDPIYSNWLREYLPEFELKEGNALDFLSEYSQDSTYLFGNLPYYISSELTLNSVKNLKGLKGATFLVQKEFAKRISA
EPSSIQFYLSAYGNWSLKKDIKAGAFYPKPNVDSSILEYKSLPVFKNESGFIALECICRTAFWGKRKKLTSSFRDAPIES
LPLEVYSSENFSEKTFRTECLKALKSVNIDLDKRPEELKSKDFHEAAKILSAYISEILNIS

Sequences:

>Translated_301_residues
MSSREYPFRKVSEIRKFLESKSSAPLKKWGQNFLIDPNAIRSILDCLNFDLLSTIDRILEIGPGLGAISHGLLDFKKPVT
LFEIDPIYSNWLREYLPEFELKEGNALDFLSEYSQDSTYLFGNLPYYISSELTLNSVKNLKGLKGATFLVQKEFAKRISA
EPSSIQFYLSAYGNWSLKKDIKAGAFYPKPNVDSSILEYKSLPVFKNESGFIALECICRTAFWGKRKKLTSSFRDAPIES
LPLEVYSSENFSEKTFRTECLKALKSVNIDLDKRPEELKSKDFHEAAKILSAYISEILNIS
>Mature_300_residues
SSREYPFRKVSEIRKFLESKSSAPLKKWGQNFLIDPNAIRSILDCLNFDLLSTIDRILEIGPGLGAISHGLLDFKKPVTL
FEIDPIYSNWLREYLPEFELKEGNALDFLSEYSQDSTYLFGNLPYYISSELTLNSVKNLKGLKGATFLVQKEFAKRISAE
PSSIQFYLSAYGNWSLKKDIKAGAFYPKPNVDSSILEYKSLPVFKNESGFIALECICRTAFWGKRKKLTSSFRDAPIESL
PLEVYSSENFSEKTFRTECLKALKSVNIDLDKRPEELKSKDFHEAAKILSAYISEILNIS

Specific function: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits [H]

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786236, Length=227, Percent_Identity=27.7533039647577, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25146882, Length=215, Percent_Identity=27.4418604651163, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21358017, Length=223, Percent_Identity=30.0448430493274, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023165
- InterPro:   IPR020596
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530 [H]

Pfam domain/function: PF00398 RrnaAD [H]

EC number: =2.1.1.182 [H]

Molecular weight: Translated: 34334; Mature: 34202

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS01131 RRNA_A_DIMETH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSREYPFRKVSEIRKFLESKSSAPLKKWGQNFLIDPNAIRSILDCLNFDLLSTIDRILE
CCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
IGPGLGAISHGLLDFKKPVTLFEIDPIYSNWLREYLPEFELKEGNALDFLSEYSQDSTYL
CCCCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCEEE
FGNLPYYISSELTLNSVKNLKGLKGATFLVQKEFAKRISAEPSSIQFYLSAYGNWSLKKD
EECCCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHH
IKAGAFYPKPNVDSSILEYKSLPVFKNESGFIALECICRTAFWGKRKKLTSSFRDAPIES
CCCCCCCCCCCCCHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LPLEVYSSENFSEKTFRTECLKALKSVNIDLDKRPEELKSKDFHEAAKILSAYISEILNI
CCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCC
S
C
>Mature Secondary Structure 
SSREYPFRKVSEIRKFLESKSSAPLKKWGQNFLIDPNAIRSILDCLNFDLLSTIDRILE
CCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
IGPGLGAISHGLLDFKKPVTLFEIDPIYSNWLREYLPEFELKEGNALDFLSEYSQDSTYL
CCCCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCEEE
FGNLPYYISSELTLNSVKNLKGLKGATFLVQKEFAKRISAEPSSIQFYLSAYGNWSLKKD
EECCCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHH
IKAGAFYPKPNVDSSILEYKSLPVFKNESGFIALECICRTAFWGKRKKLTSSFRDAPIES
CCCCCCCCCCCCCHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LPLEVYSSENFSEKTFRTECLKALKSVNIDLDKRPEELKSKDFHEAAKILSAYISEILNI
CCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA