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The map label for this gene is aat

Identifier: 45656007

GI number: 45656007

Start: 113577

End: 114236

Strand: Reverse

Name: aat

Synonym: LIC10096

Alternate gene names: 45656007

Gene position: 114236-113577 (Counterclockwise)

Preceding gene: 45656008

Following gene: 45656006

Centisome position: 2.67

GC content: 35.3

Gene sequence:

>660_bases
TTGAAAGACTTCTCCGATTTTTTTCGAAACCCTCACATTTGGGATCGAGAAATTGTAGCGGTCGGAGGTGATCTTTCTCC
CGAGCGACTTTTATATGCGTATAAAAACGGTATTTTTCCCTGGTCGGATCAACCGATCCTTTGGTATTGTTTAGACCCGA
GAAGTATTTTTGATCTTAACAAACTACATATTTCTAAACGATTAAAAAGAAAAATCAATCAAAAACGTTATACGATTACA
TTCAACCGTGCATTTGAACAAGTGATGCGATGTTGTGCTTATCGTCCAGGTGAAGATACTTGGATCACAGATCTTTTTAT
CAAAAGTTACACTGAATTTCATAAACTTGGTTATGCTCATTCTTTAGAAGTTTGGGACGAAAACGGAAAGTTAGGTGGAG
GAGTTTACGGAATTGCAATCGGAAATTTTTTTGCCGGTGAATCTATGTTTTCTTTCATTCCAGACTTTGGAAAAATAGGA
CTCTTTCATTTATTTGAAACTTTAAAAAAAGATCATTTTACTCTGTTCGATACTCAACAATTAAATCTAGTTACTCTAAG
TCTTGGAGCTTATCAGATTCCAAAAAAAGAATATCTCAAACGATTAGAATCTGCCGTAGCTTCCGGGAAAAAATGGAATC
CTTCCCATTTCGTTCTTTAA

Upstream 100 bases:

>100_bases
GTCTATTCCATCGAAGAATCTTTTTCACTTTTACCGTCTTACAAAATATGAAAATCCTAAATTATAAAGTTTTAGAAAAT
TCTAAAATAGGAAACAAACC

Downstream 100 bases:

>100_bases
AAAACGTATTTACATTTTTCCTGAGGATGTTGGACTTCTCCAATCAATCATTCTATTCAATAGGAAATTTACAAATGACC
CTTTTTAAGAAAATTCTTAT

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKDFSDFFRNPHIWDREIVAVGGDLSPERLLYAYKNGIFPWSDQPILWYCLDPRSIFDLNKLHISKRLKRKINQKRYTIT
FNRAFEQVMRCCAYRPGEDTWITDLFIKSYTEFHKLGYAHSLEVWDENGKLGGGVYGIAIGNFFAGESMFSFIPDFGKIG
LFHLFETLKKDHFTLFDTQQLNLVTLSLGAYQIPKKEYLKRLESAVASGKKWNPSHFVL

Sequences:

>Translated_219_residues
MKDFSDFFRNPHIWDREIVAVGGDLSPERLLYAYKNGIFPWSDQPILWYCLDPRSIFDLNKLHISKRLKRKINQKRYTIT
FNRAFEQVMRCCAYRPGEDTWITDLFIKSYTEFHKLGYAHSLEVWDENGKLGGGVYGIAIGNFFAGESMFSFIPDFGKIG
LFHLFETLKKDHFTLFDTQQLNLVTLSLGAYQIPKKEYLKRLESAVASGKKWNPSHFVL
>Mature_219_residues
MKDFSDFFRNPHIWDREIVAVGGDLSPERLLYAYKNGIFPWSDQPILWYCLDPRSIFDLNKLHISKRLKRKINQKRYTIT
FNRAFEQVMRCCAYRPGEDTWITDLFIKSYTEFHKLGYAHSLEVWDENGKLGGGVYGIAIGNFFAGESMFSFIPDFGKIG
LFHLFETLKKDHFTLFDTQQLNLVTLSLGAYQIPKKEYLKRLESAVASGKKWNPSHFVL

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine [H]

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family [H]

Homologues:

Organism=Escherichia coli, GI1787111, Length=187, Percent_Identity=46.524064171123, Blast_Score=164, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR004616 [H]

Pfam domain/function: PF03588 Leu_Phe_trans [H]

EC number: =2.3.2.6 [H]

Molecular weight: Translated: 25597; Mature: 25597

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFSDFFRNPHIWDREIVAVGGDLSPERLLYAYKNGIFPWSDQPILWYCLDPRSIFDLN
CCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHH
KLHISKRLKRKINQKRYTITFNRAFEQVMRCCAYRPGEDTWITDLFIKSYTEFHKLGYAH
HHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCE
SLEVWDENGKLGGGVYGIAIGNFFAGESMFSFIPDFGKIGLFHLFETLKKDHFTLFDTQQ
EEEEECCCCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCC
LNLVTLSLGAYQIPKKEYLKRLESAVASGKKWNPSHFVL
EEEEEEECCCEECCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKDFSDFFRNPHIWDREIVAVGGDLSPERLLYAYKNGIFPWSDQPILWYCLDPRSIFDLN
CCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHH
KLHISKRLKRKINQKRYTITFNRAFEQVMRCCAYRPGEDTWITDLFIKSYTEFHKLGYAH
HHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCE
SLEVWDENGKLGGGVYGIAIGNFFAGESMFSFIPDFGKIGLFHLFETLKKDHFTLFDTQQ
EEEEECCCCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCC
LNLVTLSLGAYQIPKKEYLKRLESAVASGKKWNPSHFVL
EEEEEEECCCEECCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA