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The map label for this gene is trkA [H]

Identifier: 45359162

GI number: 45359162

Start: 1547298

End: 1547963

Strand: Direct

Name: trkA [H]

Synonym: MMP1599

Alternate gene names: 45359162

Gene position: 1547298-1547963 (Clockwise)

Preceding gene: 45359161

Following gene: 45359166

Centisome position: 93.15

GC content: 37.09

Gene sequence:

>666_bases
ATGTATATTATAGTTGCAGGAATGGGCAGAGTTGGAATTTCACTTGCAAAGTCGCTTTCAGGTAAAGGACACGATTTAGT
AATACTGGACCAAAACAAAAAAACATGTGAAGAAGTTGCAGGCGAAATCGATGCTCTGGTAATTAATGGAGACTGTACCA
AAACAAAGTCGCTTGAAAACGCAGGAATTGAAGATGCAGACATATTTATCGCGGTTACTGGAAATCAGGAAATTAATCTA
ATCAGTGGATTGATTGCAAAAAAATTCAACGTTTCAAAAACTATCGCAAGAGTAAGTGAGCCAGATTACAAGGACGTATT
TGAAAGCCTTGGAATTGGAGTTGTAATCAGCCCCGAACTTGTTGCAGCAAATTATATCGAAAAATTAATTGATAGGCCGG
GTGTTGTAGACCTTGCAATCGTTGGAAGAGGCGATGCAGAGATTTTAGAGCTTATAATTCCTCCAACGTCAAAAGTTGCA
GATAAAAAAATCAGGGAACTTGGCGGAACAAAAGACTACGTTATAATCGCAATTTACGAAGGAAACGAATTAAAAATCCC
TGACGGAAGTACTGAATTAAAAGCGTACGACAGAATCTTAATTTTAGCTAAAACAGACTCCTTAGATGAAGTTAGAAAAG
TATTTTCAAGCGAAAACAAGGAATAA

Upstream 100 bases:

>100_bases
GATGGAAGAAGAACTTTTTATAGAATTGCCCCATTATCACGGTGCTTATGATGAATATTTCGAAAAAATAATTGTAAAAA
AGTAAAAAAAGGTAAATTTT

Downstream 100 bases:

>100_bases
TTTAAAAATTAAAAATAACTTTTTTAAAATTTATTTTAGGTAATTAATACAGTAATCTGCAATTTTTTTGGGAACATTTA
CAAAATTCATCATTCCTCTA

Product: TrkA-N domain-containing protein

Products: NA

Alternate protein names: K(+)-uptake protein trkA homolog [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MYIIVAGMGRVGISLAKSLSGKGHDLVILDQNKKTCEEVAGEIDALVINGDCTKTKSLENAGIEDADIFIAVTGNQEINL
ISGLIAKKFNVSKTIARVSEPDYKDVFESLGIGVVISPELVAANYIEKLIDRPGVVDLAIVGRGDAEILELIIPPTSKVA
DKKIRELGGTKDYVIIAIYEGNELKIPDGSTELKAYDRILILAKTDSLDEVRKVFSSENKE

Sequences:

>Translated_221_residues
MYIIVAGMGRVGISLAKSLSGKGHDLVILDQNKKTCEEVAGEIDALVINGDCTKTKSLENAGIEDADIFIAVTGNQEINL
ISGLIAKKFNVSKTIARVSEPDYKDVFESLGIGVVISPELVAANYIEKLIDRPGVVDLAIVGRGDAEILELIIPPTSKVA
DKKIRELGGTKDYVIIAIYEGNELKIPDGSTELKAYDRILILAKTDSLDEVRKVFSSENKE
>Mature_221_residues
MYIIVAGMGRVGISLAKSLSGKGHDLVILDQNKKTCEEVAGEIDALVINGDCTKTKSLENAGIEDADIFIAVTGNQEINL
ISGLIAKKFNVSKTIARVSEPDYKDVFESLGIGVVISPELVAANYIEKLIDRPGVVDLAIVGRGDAEILELIIPPTSKVA
DKKIRELGGTKDYVIIAIYEGNELKIPDGSTELKAYDRILILAKTDSLDEVRKVFSSENKE

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=228, Percent_Identity=28.9473684210526, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 23861; Mature: 23861

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIIVAGMGRVGISLAKSLSGKGHDLVILDQNKKTCEEVAGEIDALVINGDCTKTKSLEN
CEEEEECCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCEEEEEECCCCCCCCCHHH
AGIEDADIFIAVTGNQEINLISGLIAKKFNVSKTIARVSEPDYKDVFESLGIGVVISPEL
CCCCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHCCCCEEECCHH
VAANYIEKLIDRPGVVDLAIVGRGDAEILELIIPPTSKVADKKIRELGGTKDYVIIAIYE
HHHHHHHHHHCCCCEEEEEEECCCCHHEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEE
GNELKIPDGSTELKAYDRILILAKTDSLDEVRKVFSSENKE
CCEEECCCCCCCCEEEEEEEEEEECCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MYIIVAGMGRVGISLAKSLSGKGHDLVILDQNKKTCEEVAGEIDALVINGDCTKTKSLEN
CEEEEECCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCEEEEEECCCCCCCCCHHH
AGIEDADIFIAVTGNQEINLISGLIAKKFNVSKTIARVSEPDYKDVFESLGIGVVISPEL
CCCCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHCCCCEEECCHH
VAANYIEKLIDRPGVVDLAIVGRGDAEILELIIPPTSKVADKKIRELGGTKDYVIIAIYE
HHHHHHHHHHCCCCEEEEEEECCCCHHEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEE
GNELKIPDGSTELKAYDRILILAKTDSLDEVRKVFSSENKE
CCEEECCCCCCCCEEEEEEEEEEECCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]