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The map label for this gene is iscS [C]

Identifier: 45358803

GI number: 45358803

Start: 1225667

End: 1226809

Strand: Direct

Name: iscS [C]

Synonym: MMP1240

Alternate gene names: 45358803

Gene position: 1225667-1226809 (Clockwise)

Preceding gene: 45358802

Following gene: 45358804

Centisome position: 73.78

GC content: 34.3

Gene sequence:

>1143_bases
ATGGACATAAATACGGATAAATACAAAAATATTACGAGAAATCTTGAAAGGGAAATGATTAACTTAAATCCAATTCAAAG
AGGGGGAATTCTTCCAACTGAATCTAAAAAAATAATCTACGAATACTGGGATGGGTACAGTGTCTGTGATTACTGTTCGG
GAAGACTCGACCAAATCGAAACTCCCCCTATAAACGAATTTTTAGAAGACATGTCCAAATTTTTAGGAATGGATATAACA
AGACCTACACACGGTGCAAGGGAAAGTAAATACGCTGTTATGAATTCTATCTGTAAAGAAGGCGATTACGTAGTGTTGGA
TGGAAATGCACACTATACCTCATACGTAGCACTTGAAAGAGCAAAATTAAACTATGAAAAAACTGATATTGAGGAATACC
CGACATTTAGAGTAATTCCTGAAAGTTATGCTGAAAAAATCGATATGCTTGAAGACTCTAAAAAAAATATTGGATTGATC
CTTTTGACACACGTCGATGGAAATTATGGAAACGTTGCAGATGTTGAAAAGGTTGGAAAAATTGCAAAATCAAAAGGATA
CCCATTTTTATTAAATTGTGCCTATTCTGCTGGAAGAATGCCTATTGATGGAAAAAAATTAAATGTTGACTTTATTGCAG
CATCAGGACATAAAAGTATGGCTGCATCAGGCCCTTGCGGTCTTCTTTCAATAAATAAAAAATATGAAAATGAAGTGCTT
GAAACTTCAAAAGTAAATGTATTAAAAGAACTCCAGATGCTTGGTTGCACCAGTAGGGGAATTCCAATTTTAAGTTTGAT
GGCGAGCTTTGAACACCTGATTGAAAGGGTTAAAAAGTGGGATTTAGAACTTGAAAAAACAAGAAAAGTAGTTAACGAGC
TTGAACCATTAGGATTTAAACAGATTGGGGAAAAACCAAGAAACCACGATATCATAAGATTTGAAACCCCGATTTTAGAT
GAAATTGCAGAAAAAGATAAACGAAGAGGATTTTTCTTCTACGAAGAATTGAAGAAAAGAGGAATCGGCGGAATCAGAAG
AGGAGTTACAAAAGAATTCAAAATGAGTGTTTATGGATTAACCAATACTCAGGTTGACTACGTGATAAATAGCATGAAAT
CTATTATAAACGAGTTAAGGTGA

Upstream 100 bases:

>100_bases
GATAGAAAGAATAAATACGGAACTTAAAAAAATAGGGTTTGAAAAGGTTGTACTCGACCTCAATTTTAAATAATTAAATT
ACGCGAGAATTGGTGATTTT

Downstream 100 bases:

>100_bases
ATTTAATGAGTTCTAAGTATGTACTCCCAGTAATTGCGCTTTTAATTCTTGCGAGCGCAATATATTTCTCGTTTGGCCCA
GATACTCCTGAAAAGTACGT

Product: Sep-tRNA:Cys-tRNA synthetase

Products: NA

Alternate protein names: Sep-tRNA:Cys-tRNA synthase; SepCysS [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDINTDKYKNITRNLEREMINLNPIQRGGILPTESKKIIYEYWDGYSVCDYCSGRLDQIETPPINEFLEDMSKFLGMDIT
RPTHGARESKYAVMNSICKEGDYVVLDGNAHYTSYVALERAKLNYEKTDIEEYPTFRVIPESYAEKIDMLEDSKKNIGLI
LLTHVDGNYGNVADVEKVGKIAKSKGYPFLLNCAYSAGRMPIDGKKLNVDFIAASGHKSMAASGPCGLLSINKKYENEVL
ETSKVNVLKELQMLGCTSRGIPILSLMASFEHLIERVKKWDLELEKTRKVVNELEPLGFKQIGEKPRNHDIIRFETPILD
EIAEKDKRRGFFFYEELKKRGIGGIRRGVTKEFKMSVYGLTNTQVDYVINSMKSIINELR

Sequences:

>Translated_380_residues
MDINTDKYKNITRNLEREMINLNPIQRGGILPTESKKIIYEYWDGYSVCDYCSGRLDQIETPPINEFLEDMSKFLGMDIT
RPTHGARESKYAVMNSICKEGDYVVLDGNAHYTSYVALERAKLNYEKTDIEEYPTFRVIPESYAEKIDMLEDSKKNIGLI
LLTHVDGNYGNVADVEKVGKIAKSKGYPFLLNCAYSAGRMPIDGKKLNVDFIAASGHKSMAASGPCGLLSINKKYENEVL
ETSKVNVLKELQMLGCTSRGIPILSLMASFEHLIERVKKWDLELEKTRKVVNELEPLGFKQIGEKPRNHDIIRFETPILD
EIAEKDKRRGFFFYEELKKRGIGGIRRGVTKEFKMSVYGLTNTQVDYVINSMKSIINELR
>Mature_380_residues
MDINTDKYKNITRNLEREMINLNPIQRGGILPTESKKIIYEYWDGYSVCDYCSGRLDQIETPPINEFLEDMSKFLGMDIT
RPTHGARESKYAVMNSICKEGDYVVLDGNAHYTSYVALERAKLNYEKTDIEEYPTFRVIPESYAEKIDMLEDSKKNIGLI
LLTHVDGNYGNVADVEKVGKIAKSKGYPFLLNCAYSAGRMPIDGKKLNVDFIAASGHKSMAASGPCGLLSINKKYENEVL
ETSKVNVLKELQMLGCTSRGIPILSLMASFEHLIERVKKWDLELEKTRKVVNELEPLGFKQIGEKPRNHDIIRFETPILD
EIAEKDKRRGFFFYEELKKRGIGGIRRGVTKEFKMSVYGLTNTQVDYVINSMKSIINELR

Specific function: Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) [H]

COG id: COG1103

COG function: function code R; Archaea-specific pyridoxal phosphate-dependent enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SepCysS family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR013375
- InterPro:   IPR008829 [H]

Pfam domain/function: PF05889 SLA_LP_auto_ag [H]

EC number: =2.5.1.73 [H]

Molecular weight: Translated: 43377; Mature: 43377

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINTDKYKNITRNLEREMINLNPIQRGGILPTESKKIIYEYWDGYSVCDYCSGRLDQIE
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCC
TPPINEFLEDMSKFLGMDITRPTHGARESKYAVMNSICKEGDYVVLDGNAHYTSYVALER
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHH
AKLNYEKTDIEEYPTFRVIPESYAEKIDMLEDSKKNIGLILLTHVDGNYGNVADVEKVGK
HHCCCCCCCHHHCCCEEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHH
IAKSKGYPFLLNCAYSAGRMPIDGKKLNVDFIAASGHKSMAASGPCGLLSINKKYENEVL
HHHCCCCCEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEECHHHHHHHH
ETSKVNVLKELQMLGCTSRGIPILSLMASFEHLIERVKKWDLELEKTRKVVNELEPLGFK
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
QIGEKPRNHDIIRFETPILDEIAEKDKRRGFFFYEELKKRGIGGIRRGVTKEFKMSVYGL
HHCCCCCCCCEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHCCCHHHHEEEEEC
TNTQVDYVINSMKSIINELR
CCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDINTDKYKNITRNLEREMINLNPIQRGGILPTESKKIIYEYWDGYSVCDYCSGRLDQIE
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCC
TPPINEFLEDMSKFLGMDITRPTHGARESKYAVMNSICKEGDYVVLDGNAHYTSYVALER
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHH
AKLNYEKTDIEEYPTFRVIPESYAEKIDMLEDSKKNIGLILLTHVDGNYGNVADVEKVGK
HHCCCCCCCHHHCCCEEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHH
IAKSKGYPFLLNCAYSAGRMPIDGKKLNVDFIAASGHKSMAASGPCGLLSINKKYENEVL
HHHCCCCCEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEECHHHHHHHH
ETSKVNVLKELQMLGCTSRGIPILSLMASFEHLIERVKKWDLELEKTRKVVNELEPLGFK
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
QIGEKPRNHDIIRFETPILDEIAEKDKRRGFFFYEELKKRGIGGIRRGVTKEFKMSVYGL
HHCCCCCCCCEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHCCCHHHHEEEEEC
TNTQVDYVINSMKSIINELR
CCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA