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The map label for this gene is dapB [H]

Identifier: 45358486

GI number: 45358486

Start: 911732

End: 912544

Strand: Direct

Name: dapB [H]

Synonym: MMP0923

Alternate gene names: 45358486

Gene position: 911732-912544 (Clockwise)

Preceding gene: 45358485

Following gene: 45358487

Centisome position: 54.89

GC content: 37.27

Gene sequence:

>813_bases
ATGGTTAAAGTAGCAGTTACAGGAGCACTCGGTAGAATGGGAAGCGGAATTATAAAAACAATTACTGAAACTGATGGATT
AGATGTAGTTGCAGCAATTGATATTCCAAATCACCCAAAAAAAGGTCAGGACGTTGGGGAATTAACGGGCCTTGGAAAAA
TTGGTGTAGCATTAAGTACTTCAGACGAACTTGAAGCTGTTTTAAAAGAATCTGGTGCAGAAGTATTAGTTGATTTTACT
GCAGCTGCCCCTTGTGTTCAAACCGCAAAAACAGCAAGCAAACTTGGAGTAAATTTAGTTATTGGAACTACAGGATTTAC
GCCTGAACAAAGAGCTGAAATGGAAGATGCAATTTCAAAAAACAAAGTTGCTGCAACCATTTCACAAAACTATGCAGTTG
GTGTAAATATATTCTTTAAAACCCTTGAACTTTTAGCACAAAAACTCGGGGATTACGATATCGAAATTCTTGAAATGCAC
CACAAATTCAAAAAAGATGCACCAAGCGGAACTGCATTAAGAGCTGCTGAAATTATTCAAAATAACTTAAACAGAGACTC
CAACGTAATCTATGGAAGAGAAGGAATAACTGGAGAAAGAACAAAAGAAGAAATCTGTATCCACGCATTAAGAGGCGGAG
ATATTGTTGGAGACCACAGCGTAATATTCACAACAGAAGGAGAAAGGCTTGAACTTTCACATAGGGTAACCAGCAGACAA
TCCCTCGTTTCAGGAGCAGTCCTTGCAATTAAATTTGTTGCTCAAAAGAAAGAAGGTATTTACAATACTTTTGATGTTTT
AGACCTTAATTAG

Upstream 100 bases:

>100_bases
AAAATATAGACAAGGCTTCTGGTGTCGTAGATAATTTAAAATGTAAAATTGATAGTTATATGGACAATATTAACGAAAAA
GCGGAAGCTTAGGTGGAAAT

Downstream 100 bases:

>100_bases
GTGAAATTTTGAAAGAATTTATAATTAAAGCTAACAAAGCCGTAACTAATGGTGAAATTAACTTAAAAGATCTTCCGGGA
AGTTCTGGAAGATTGGATTT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MVKVAVTGALGRMGSGIIKTITETDGLDVVAAIDIPNHPKKGQDVGELTGLGKIGVALSTSDELEAVLKESGAEVLVDFT
AAAPCVQTAKTASKLGVNLVIGTTGFTPEQRAEMEDAISKNKVAATISQNYAVGVNIFFKTLELLAQKLGDYDIEILEMH
HKFKKDAPSGTALRAAEIIQNNLNRDSNVIYGREGITGERTKEEICIHALRGGDIVGDHSVIFTTEGERLELSHRVTSRQ
SLVSGAVLAIKFVAQKKEGIYNTFDVLDLN

Sequences:

>Translated_270_residues
MVKVAVTGALGRMGSGIIKTITETDGLDVVAAIDIPNHPKKGQDVGELTGLGKIGVALSTSDELEAVLKESGAEVLVDFT
AAAPCVQTAKTASKLGVNLVIGTTGFTPEQRAEMEDAISKNKVAATISQNYAVGVNIFFKTLELLAQKLGDYDIEILEMH
HKFKKDAPSGTALRAAEIIQNNLNRDSNVIYGREGITGERTKEEICIHALRGGDIVGDHSVIFTTEGERLELSHRVTSRQ
SLVSGAVLAIKFVAQKKEGIYNTFDVLDLN
>Mature_270_residues
MVKVAVTGALGRMGSGIIKTITETDGLDVVAAIDIPNHPKKGQDVGELTGLGKIGVALSTSDELEAVLKESGAEVLVDFT
AAAPCVQTAKTASKLGVNLVIGTTGFTPEQRAEMEDAISKNKVAATISQNYAVGVNIFFKTLELLAQKLGDYDIEILEMH
HKFKKDAPSGTALRAAEIIQNNLNRDSNVIYGREGITGERTKEEICIHALRGGDIVGDHSVIFTTEGERLELSHRVTSRQ
SLVSGAVLAIKFVAQKKEGIYNTFDVLDLN

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=272, Percent_Identity=39.3382352941176, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 28861; Mature: 28861

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVAVTGALGRMGSGIIKTITETDGLDVVAAIDIPNHPKKGQDVGELTGLGKIGVALST
CEEEEEECCHHHCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCEEEEEEC
SDELEAVLKESGAEVLVDFTAAAPCVQTAKTASKLGVNLVIGTTGFTPEQRAEMEDAISK
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCC
NKVAATISQNYAVGVNIFFKTLELLAQKLGDYDIEILEMHHKFKKDAPSGTALRAAEIIQ
CCEEEEECCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
NNLNRDSNVIYGREGITGERTKEEICIHALRGGDIVGDHSVIFTTEGERLELSHRVTSRQ
HHCCCCCCEEEECCCCCCCCCHHHHHEEEECCCCEECCCEEEEEECCCEEEHHHHHHHHH
SLVSGAVLAIKFVAQKKEGIYNTFDVLDLN
HHHHHHHHHHHHHHHHCCCCCCEEEEEECC
>Mature Secondary Structure
MVKVAVTGALGRMGSGIIKTITETDGLDVVAAIDIPNHPKKGQDVGELTGLGKIGVALST
CEEEEEECCHHHCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCEEEEEEC
SDELEAVLKESGAEVLVDFTAAAPCVQTAKTASKLGVNLVIGTTGFTPEQRAEMEDAISK
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCC
NKVAATISQNYAVGVNIFFKTLELLAQKLGDYDIEILEMHHKFKKDAPSGTALRAAEIIQ
CCEEEEECCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
NNLNRDSNVIYGREGITGERTKEEICIHALRGGDIVGDHSVIFTTEGERLELSHRVTSRQ
HHCCCCCCEEEECCCCCCCCCHHHHHEEEECCCCEECCCEEEEEECCCEEEHHHHHHHHH
SLVSGAVLAIKFVAQKKEGIYNTFDVLDLN
HHHHHHHHHHHHHHHHCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA