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The map label for this gene is panE [C]

Identifier: 45358235

GI number: 45358235

Start: 660406

End: 661326

Strand: Direct

Name: panE [C]

Synonym: MMP0672

Alternate gene names: 45358235

Gene position: 660406-661326 (Clockwise)

Preceding gene: 45358234

Following gene: 45358241

Centisome position: 39.76

GC content: 33.12

Gene sequence:

>921_bases
ATGAATGTTTTAATTATTGGGGCCGGTGCTGTCGGATTATGTCTGGCTGCTAAATTATCAAATGTAGCAGATGTTTTTGC
AGTAACAAGGGAGAGAAATGCAAAAATCATACGCGAATCTGGTTTTAAAATGACTGGAATCTGGGGGGACGGAACATATA
ACTTTGAAACTTCTGAAAATGTTCCAGAACGTGATTTTGACTACATTATTATATCTTCAAAAGGACTTGCAACAAAATCA
ATCTGCGAGCAATTTAAAGACGTTATAAAAGGCAAAAATGTTATCAGCATCCAAAATGGTGTTGGAAACGAAGAAATAAT
TTCAGAATATACTGATAAAGTGATTGGCGGAACTATTATAACAGGTTTTGAGTGGAAGGGGGACGCAAAAGTACACGTTT
CAGTAGAAGGAGGCCCGATGACGTTAGGAAGATTTCCAAATGGAACGGATGATGAAGTAAATACTTTTGTAAAATTAGTA
AAAAGTTCTGGAATACCAATTGATGAAACAGAAAATATTCAGGGCGCAATATGGTCAAAAACAATTTATAACTGCGCATT
AAATCCACTTGGAGCAGTTATGAATGTATCCTATGGTGAACTTTCAAATGAACACTCATGGAACCTAATTAAAAATATCG
TATATGAAATATTTGAAGTAACTTCCAAAAAAGGAGTAATTTTACCTTGGAAAACGCCAGAAGAATATTTAAAATATTTA
AAAGAGTTCCAGCTTCCAAATACTGCTGCACACCACTCTTCAATGCTTCAAGATATTTCAAAAGGAAATATAACAGAAAT
AGACTTTTTAAATGGTGCAGTAACATCAATTGCAAAAGAATTTGGGATAAAAACGCCGTATAATGAATTTATTACTGAAC
AGATAAAATTCCTTGAAAATTTAAAATCAAAAAAGGAATAA

Upstream 100 bases:

>100_bases
ATAATATTTTTTATTTTTAACTATTTATCTAAATCTTTTAATACTATTTTTACAGATATTTAAATTAAATTTAGTTTAAC
TTGAAAACGAGGGTTTTTAA

Downstream 100 bases:

>100_bases
TTATTTAAAATTTTTTTATTTTGAAATTGATGATTTGCTTATTTTAGGTTCGTTATATAATGGATCTATCTCAATTGCTT
TATCATAGCACATCAGTGCT

Product: binding-protein dependent transport system inner membrane protein

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNVLIIGAGAVGLCLAAKLSNVADVFAVTRERNAKIIRESGFKMTGIWGDGTYNFETSENVPERDFDYIIISSKGLATKS
ICEQFKDVIKGKNVISIQNGVGNEEIISEYTDKVIGGTIITGFEWKGDAKVHVSVEGGPMTLGRFPNGTDDEVNTFVKLV
KSSGIPIDETENIQGAIWSKTIYNCALNPLGAVMNVSYGELSNEHSWNLIKNIVYEIFEVTSKKGVILPWKTPEEYLKYL
KEFQLPNTAAHHSSMLQDISKGNITEIDFLNGAVTSIAKEFGIKTPYNEFITEQIKFLENLKSKKE

Sequences:

>Translated_306_residues
MNVLIIGAGAVGLCLAAKLSNVADVFAVTRERNAKIIRESGFKMTGIWGDGTYNFETSENVPERDFDYIIISSKGLATKS
ICEQFKDVIKGKNVISIQNGVGNEEIISEYTDKVIGGTIITGFEWKGDAKVHVSVEGGPMTLGRFPNGTDDEVNTFVKLV
KSSGIPIDETENIQGAIWSKTIYNCALNPLGAVMNVSYGELSNEHSWNLIKNIVYEIFEVTSKKGVILPWKTPEEYLKYL
KEFQLPNTAAHHSSMLQDISKGNITEIDFLNGAVTSIAKEFGIKTPYNEFITEQIKFLENLKSKKE
>Mature_306_residues
MNVLIIGAGAVGLCLAAKLSNVADVFAVTRERNAKIIRESGFKMTGIWGDGTYNFETSENVPERDFDYIIISSKGLATKS
ICEQFKDVIKGKNVISIQNGVGNEEIISEYTDKVIGGTIITGFEWKGDAKVHVSVEGGPMTLGRFPNGTDDEVNTFVKLV
KSSGIPIDETENIQGAIWSKTIYNCALNPLGAVMNVSYGELSNEHSWNLIKNIVYEIFEVTSKKGVILPWKTPEEYLKYL
KEFQLPNTAAHHSSMLQDISKGNITEIDFLNGAVTSIAKEFGIKTPYNEFITEQIKFLENLKSKKE

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=308, Percent_Identity=25.6493506493506, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33848; Mature: 33848

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLIIGAGAVGLCLAAKLSNVADVFAVTRERNAKIIRESGFKMTGIWGDGTYNFETSEN
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEEECCCEECCCCCCC
VPERDFDYIIISSKGLATKSICEQFKDVIKGKNVISIQNGVGNEEIISEYTDKVIGGTII
CCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCEEE
TGFEWKGDAKVHVSVEGGPMTLGRFPNGTDDEVNTFVKLVKSSGIPIDETENIQGAIWSK
EEEEECCCCEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
TIYNCALNPLGAVMNVSYGELSNEHSWNLIKNIVYEIFEVTSKKGVILPWKTPEEYLKYL
HHHHHHCCHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
KEFQLPNTAAHHSSMLQDISKGNITEIDFLNGAVTSIAKEFGIKTPYNEFITEQIKFLEN
HHHCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LKSKKE
HHHCCC
>Mature Secondary Structure
MNVLIIGAGAVGLCLAAKLSNVADVFAVTRERNAKIIRESGFKMTGIWGDGTYNFETSEN
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEEECCCEECCCCCCC
VPERDFDYIIISSKGLATKSICEQFKDVIKGKNVISIQNGVGNEEIISEYTDKVIGGTII
CCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCEEE
TGFEWKGDAKVHVSVEGGPMTLGRFPNGTDDEVNTFVKLVKSSGIPIDETENIQGAIWSK
EEEEECCCCEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
TIYNCALNPLGAVMNVSYGELSNEHSWNLIKNIVYEIFEVTSKKGVILPWKTPEEYLKYL
HHHHHHCCHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
KEFQLPNTAAHHSSMLQDISKGNITEIDFLNGAVTSIAKEFGIKTPYNEFITEQIKFLEN
HHHCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LKSKKE
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]