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The map label for this gene is fmdB [H]

Identifier: 45358075

GI number: 45358075

Start: 517360

End: 518697

Strand: Direct

Name: fmdB [H]

Synonym: MMP0512

Alternate gene names: 45358075

Gene position: 517360-518697 (Clockwise)

Preceding gene: 45358074

Following gene: 45358077

Centisome position: 31.14

GC content: 37.14

Gene sequence:

>1338_bases
ATGGTTGCTGAAACATTTAAGGATATAGTATGCCCTGTTTGCGGGGGTACTTGCGATGATATTGAAGTAGAATATGATAA
GGAAAAAAGAGATATTGTTGTTAGAAACGCCTGTAAAATGGGTGCAGCTAAATTTAGAGAAATTGTAAGTAATCACCGTA
TAACTTCTCCAAAAATTAGAATAAATGGAAAACTAGAAGATTCTAAATGGGAAGATGCAATTGAAAAAGCTGCTGAAATC
CTTGTAAATGCTAAAAGACCCTTATTTTTCATGGGTTCTGAAACTTCCTGTGAAGCAATGACTGTTGGATTACATATGGG
CGAATATCTTGGCGGAATTGTAGATTCAAATTCCACGATCTGTCACGGGCCTTCTTTAATGGGGGTTCAGGAAGCTGGAA
AAGCCGGTGCAACCGCTGGTGAAACTAAAAATCGTGCAGATGTAGTTATTTACTGGGGAGTAAATCCAATGTGTTCAATG
CCACGACACATGTCAAGATATGCCGTATTTCCAAGAGGATATTTTGTTCAAAAAGGAAGAAAAGAACGAAAAGTAATTAC
TGTAGACCCGAGAGTTTCTGAAACTGCTAAGGGCTCAGATATACACTTGCAGTTAAAACCCAGCACTGATTATGAACTGT
TTTCAGCTTTAATGCTCGCAGTTAAGGGAAAGCCTATTCATCCAAGTATTGAACAGGTTACAGGTATTTCTGTTGAAAAG
ATTTTAGAAGTTGCACAAATCATGAAAAATGCAAAATTCGGGTCAATTTACGGAGGGCTTGGGTTAGCTTCATCATTTGG
TAAACACCGAAATTTGGAATGTGTTTTAACATTAAATAAAGAATTACAAAAATATGCGAAGTTTCAAATTGGTTTAATCA
GGGGGCACTGTAACGTTGCAGGATTTAACGTGCTTGCGTCATACCTTTACGGATTCCCATTCGGAGTTGATTTTTCGAGA
GGATACCCAAGATATAATCCTGGAGAACACACGACAACCGATGTTTTAAGGGAAAAAGAAGTTGATGCAGTATTTGTAAT
GTGTGCAGATTTAGGGGCTCACTTGGCCCAAGATTCAGTTAGATATATGCATGATATACCCGTAATATGCCTTGATATTG
CGCCATGCCCGTCGACATCTGTAGCAAACGTGGTTTTACCAGGAGTTATAGATGCACTCGAGTGTGATGGCACATTTTAT
AGATTTGATGAAATACCAATATATTACAAACCATTTACTCAATCCCCATTTGACTTTACGAAAAGCAATGAGGATACAAT
GGAACAGTTGTTTGAAAAAGTAAAAGAATTAAAAGAACTTAAAAAAAATAGAAAATAA

Upstream 100 bases:

>100_bases
AAGATTTTTTCTTCCTTACACTAGTTTCTTTTGGAAAATACAAAAAACATATCAAAACATTTGTTTTGGAGTTTATGTAT
TTCAAAAAACTGGTGAAAAA

Downstream 100 bases:

>100_bases
TTTTTTTACATTTTATTTGAACTTAATTTACTTTTTTTGAATTTTTAAAATTTAAAAATATTTTAGTATTATTTAATTAA
TCATATATCCAGACTTCAAC

Product: molybdenum containing formylmethanofuran dehydrogenase subunit B

Products: NA

Alternate protein names: Tungsten-containing formylmethanofuran dehydrogenase II subunit B [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MVAETFKDIVCPVCGGTCDDIEVEYDKEKRDIVVRNACKMGAAKFREIVSNHRITSPKIRINGKLEDSKWEDAIEKAAEI
LVNAKRPLFFMGSETSCEAMTVGLHMGEYLGGIVDSNSTICHGPSLMGVQEAGKAGATAGETKNRADVVIYWGVNPMCSM
PRHMSRYAVFPRGYFVQKGRKERKVITVDPRVSETAKGSDIHLQLKPSTDYELFSALMLAVKGKPIHPSIEQVTGISVEK
ILEVAQIMKNAKFGSIYGGLGLASSFGKHRNLECVLTLNKELQKYAKFQIGLIRGHCNVAGFNVLASYLYGFPFGVDFSR
GYPRYNPGEHTTTDVLREKEVDAVFVMCADLGAHLAQDSVRYMHDIPVICLDIAPCPSTSVANVVLPGVIDALECDGTFY
RFDEIPIYYKPFTQSPFDFTKSNEDTMEQLFEKVKELKELKKNRK

Sequences:

>Translated_445_residues
MVAETFKDIVCPVCGGTCDDIEVEYDKEKRDIVVRNACKMGAAKFREIVSNHRITSPKIRINGKLEDSKWEDAIEKAAEI
LVNAKRPLFFMGSETSCEAMTVGLHMGEYLGGIVDSNSTICHGPSLMGVQEAGKAGATAGETKNRADVVIYWGVNPMCSM
PRHMSRYAVFPRGYFVQKGRKERKVITVDPRVSETAKGSDIHLQLKPSTDYELFSALMLAVKGKPIHPSIEQVTGISVEK
ILEVAQIMKNAKFGSIYGGLGLASSFGKHRNLECVLTLNKELQKYAKFQIGLIRGHCNVAGFNVLASYLYGFPFGVDFSR
GYPRYNPGEHTTTDVLREKEVDAVFVMCADLGAHLAQDSVRYMHDIPVICLDIAPCPSTSVANVVLPGVIDALECDGTFY
RFDEIPIYYKPFTQSPFDFTKSNEDTMEQLFEKVKELKELKKNRK
>Mature_445_residues
MVAETFKDIVCPVCGGTCDDIEVEYDKEKRDIVVRNACKMGAAKFREIVSNHRITSPKIRINGKLEDSKWEDAIEKAAEI
LVNAKRPLFFMGSETSCEAMTVGLHMGEYLGGIVDSNSTICHGPSLMGVQEAGKAGATAGETKNRADVVIYWGVNPMCSM
PRHMSRYAVFPRGYFVQKGRKERKVITVDPRVSETAKGSDIHLQLKPSTDYELFSALMLAVKGKPIHPSIEQVTGISVEK
ILEVAQIMKNAKFGSIYGGLGLASSFGKHRNLECVLTLNKELQKYAKFQIGLIRGHCNVAGFNVLASYLYGFPFGVDFSR
GYPRYNPGEHTTTDVLREKEVDAVFVMCADLGAHLAQDSVRYMHDIPVICLDIAPCPSTSVANVVLPGVIDALECDGTFY
RFDEIPIYYKPFTQSPFDFTKSNEDTMEQLFEKVKELKELKKNRK

Specific function: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile [H]

COG id: COG1029

COG function: function code C; Formylmethanofuran dehydrogenase subunit B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fwdB family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=469, Percent_Identity=22.6012793176972, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016457
- InterPro:   IPR006656 [H]

Pfam domain/function: PF00384 Molybdopterin [H]

EC number: =1.2.99.5 [H]

Molecular weight: Translated: 49503; Mature: 49503

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAETFKDIVCPVCGGTCDDIEVEYDKEKRDIVVRNACKMGAAKFREIVSNHRITSPKIR
CCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
INGKLEDSKWEDAIEKAAEILVNAKRPLFFMGSETSCEAMTVGLHMGEYLGGIVDSNSTI
EECEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEHHHHHHHHCCEECCCCEE
CHGPSLMGVQEAGKAGATAGETKNRADVVIYWGVNPMCSMPRHMSRYAVFPRGYFVQKGR
ECCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHCCHHHHHHEECCCCHHHHCCC
KERKVITVDPRVSETAKGSDIHLQLKPSTDYELFSALMLAVKGKPIHPSIEQVTGISVEK
CCCEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCHHH
ILEVAQIMKNAKFGSIYGGLGLASSFGKHRNLECVLTLNKELQKYAKFQIGLIRGHCNVA
HHHHHHHHHCCCCCCHHCCHHHHHHCCCCCCCEEEEEECHHHHHHHHHEEEEEECCCCCH
GFNVLASYLYGFPFGVDFSRGYPRYNPGEHTTTDVLREKEVDAVFVMCADLGAHLAQDSV
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHH
RYMHDIPVICLDIAPCPSTSVANVVLPGVIDALECDGTFYRFDEIPIYYKPFTQSPFDFT
HHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCC
KSNEDTMEQLFEKVKELKELKKNRK
CCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVAETFKDIVCPVCGGTCDDIEVEYDKEKRDIVVRNACKMGAAKFREIVSNHRITSPKIR
CCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
INGKLEDSKWEDAIEKAAEILVNAKRPLFFMGSETSCEAMTVGLHMGEYLGGIVDSNSTI
EECEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEHHHHHHHHCCEECCCCEE
CHGPSLMGVQEAGKAGATAGETKNRADVVIYWGVNPMCSMPRHMSRYAVFPRGYFVQKGR
ECCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHCCHHHHHHEECCCCHHHHCCC
KERKVITVDPRVSETAKGSDIHLQLKPSTDYELFSALMLAVKGKPIHPSIEQVTGISVEK
CCCEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCHHH
ILEVAQIMKNAKFGSIYGGLGLASSFGKHRNLECVLTLNKELQKYAKFQIGLIRGHCNVA
HHHHHHHHHCCCCCCHHCCHHHHHHCCCCCCCEEEEEECHHHHHHHHHEEEEEECCCCCH
GFNVLASYLYGFPFGVDFSRGYPRYNPGEHTTTDVLREKEVDAVFVMCADLGAHLAQDSV
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHH
RYMHDIPVICLDIAPCPSTSVANVVLPGVIDALECDGTFYRFDEIPIYYKPFTQSPFDFT
HHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCC
KSNEDTMEQLFEKVKELKELKKNRK
CCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA