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The map label for this gene is infB [H]

Identifier: 45357847

GI number: 45357847

Start: 284645

End: 286441

Strand: Direct

Name: infB [H]

Synonym: MMP0284

Alternate gene names: 45357847

Gene position: 284645-286441 (Clockwise)

Preceding gene: 45357846

Following gene: 45357848

Centisome position: 17.14

GC content: 35.39

Gene sequence:

>1797_bases
ATGGCATTAAGATGTCCGATTGTGAGTGTTCTCGGTCACGTTGATCACGGAAAAACTTCCCTTTTAGATAAAATTAGAAG
AACAAGGGTTACTCAGAGAGAGGCTGGGGGAATCACTCAACATATCGGTGCAAGTGAAATACCGATAAATACCATAAAAA
AAGTTTCAAAGGACCTTTTAGGATTATTTAAGGCAGATTTATCTATTCCCGGAATTTTGGTTATAGATACGCCAGGACAC
GAAGCATTTACCTCCCTTAGAAAAAGAGGGGGTGCTTTAGCAGACATTGCAATACTTGTTGTGGATATAAATGAAGGATT
TAAGCCCCAAACAATTGAAGCAATAAATATTTTGAAACAGTGCAAAACACCTTTCGTAGTTGCTGCAAATAAAGTGGATA
GGATTCCAGGCTGGAATTCAAGCGAAGGTCCATTCATTTTAAATTTCAACGAAAAAAACCAGCACCCAAATGCAATGACT
GAGTTTGAAATAAGGCTCTATGAAAATGTTATAAAACACTTAAATGAACTTGGATTTGATGCAGATTTGTTTTCAAGAGT
TAAAGATACTACAAAAACGATAAATGTGGTTCCAGTATCTGCAATGACTGGCGAAGGAGTTCCTGATTTACTTGTTATAA
TTTCAGGATTAGCACAGAGATTTTTAGAACAAAAACTGGCTTTAAACGTTGAAGGTTATGCAAAAGGTACAGTTTTGGAA
TTAAAAGAAGAAAAAGGACTTGGAAAAACAATTGATGCAATAATTTACGATGGAATTGCAAAAACTGGCGATTTTTTAGT
TGTTGGAAATCCTGACGGCGTTCTTGTATCAAAAATCAAGGCACTTTTAAAACCAAAAGAACTCGACGAAATGAGGGATC
CAAAGGATAAATTTAAACCTTCAAAACAGATTTCTGCGGCAACAGGTGTTAAAATATCTGCACCTGATTTAGATAGTGTT
ATTGCGGGAAGCCCTTTAAGAATTGTTCCAAAAAATCAGGTTGAAGCTGCAAAAGAAGAAGTTCTTGAAGAAGTCGAAGA
GTTTACAATTCTAACAGATGACGAAGGAATAATTATCAAAGCAGATACGATGGGTTCTTTGGAAGCTCTTGCAAATGAAC
TTCGAAAAGTAAATGCTAAAATCAAAAAAGCAGAAGTTGGGGACATCTCTAAAAAAGATGTTATCGAAGCTTCATCATAC
GCTTCAACAAACCCGTTAAATGGACTTATTATTTCTTTTAACACAAAAGTGCTGGCAGATGCAAAAGCTGAAATCGAAAA
ATCAGACGTTAAATTGCTCGAAGGAAAAATTATCTATAAATTAGTCGAAGAACACGAAGAATGGACAAAAGAAATGGAAG
AATTAATGAAATCTGATGAAATAAACAGATTGACAAAACCAGCAATGATTAAAATCCTTCCAAACTGTATCTTTAGACAG
AAAGAGCCTGCAGTATGTGGTGTTGAAGTATTATATGGTACTTTAAAAATTGGAAGTCCCATAATGTCTGAGGATGGAAA
AAAACTCGGATATGTTAAGGAAATGAGGGACAACCAGCAGGAAAATATAAAAGAAGCAAAAGTTGGTATGCAGGTTCCTG
TTTCAATCGATGGAAATATAGTTCTTGGTAGAAATGCAAAAGAAAACGATATACTCTATGTCGAAGTACCAGAACCCGAA
GCAAGGAAATTACACCACGAATTTAAGGATGAATTGAGGGGCGACGAAAAAGAAGCTCTTTCAAGATACATGGAATTGAA
ACAGAAGATCGAAAATAATATATTTTGGGGAATGTAG

Upstream 100 bases:

>100_bases
TATTTAGATTACTAACTTCTGTTTCGGATTTTTATCAACTTTATAATTTGTACTTGGATGAAACACAGATTTTAGAAATT
AATATTAACTGGTGATTTTT

Downstream 100 bases:

>100_bases
GCCATTAAACCGCATTTATACAAATGACGAAACATCAACAATATATACTCATTACGTTAAATGTAGTTATGGACTACTAT
TCGGAATTTTCAAATTTAAC

Product: translation initiation factor IF-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MALRCPIVSVLGHVDHGKTSLLDKIRRTRVTQREAGGITQHIGASEIPINTIKKVSKDLLGLFKADLSIPGILVIDTPGH
EAFTSLRKRGGALADIAILVVDINEGFKPQTIEAINILKQCKTPFVVAANKVDRIPGWNSSEGPFILNFNEKNQHPNAMT
EFEIRLYENVIKHLNELGFDADLFSRVKDTTKTINVVPVSAMTGEGVPDLLVIISGLAQRFLEQKLALNVEGYAKGTVLE
LKEEKGLGKTIDAIIYDGIAKTGDFLVVGNPDGVLVSKIKALLKPKELDEMRDPKDKFKPSKQISAATGVKISAPDLDSV
IAGSPLRIVPKNQVEAAKEEVLEEVEEFTILTDDEGIIIKADTMGSLEALANELRKVNAKIKKAEVGDISKKDVIEASSY
ASTNPLNGLIISFNTKVLADAKAEIEKSDVKLLEGKIIYKLVEEHEEWTKEMEELMKSDEINRLTKPAMIKILPNCIFRQ
KEPAVCGVEVLYGTLKIGSPIMSEDGKKLGYVKEMRDNQQENIKEAKVGMQVPVSIDGNIVLGRNAKENDILYVEVPEPE
ARKLHHEFKDELRGDEKEALSRYMELKQKIENNIFWGM

Sequences:

>Translated_598_residues
MALRCPIVSVLGHVDHGKTSLLDKIRRTRVTQREAGGITQHIGASEIPINTIKKVSKDLLGLFKADLSIPGILVIDTPGH
EAFTSLRKRGGALADIAILVVDINEGFKPQTIEAINILKQCKTPFVVAANKVDRIPGWNSSEGPFILNFNEKNQHPNAMT
EFEIRLYENVIKHLNELGFDADLFSRVKDTTKTINVVPVSAMTGEGVPDLLVIISGLAQRFLEQKLALNVEGYAKGTVLE
LKEEKGLGKTIDAIIYDGIAKTGDFLVVGNPDGVLVSKIKALLKPKELDEMRDPKDKFKPSKQISAATGVKISAPDLDSV
IAGSPLRIVPKNQVEAAKEEVLEEVEEFTILTDDEGIIIKADTMGSLEALANELRKVNAKIKKAEVGDISKKDVIEASSY
ASTNPLNGLIISFNTKVLADAKAEIEKSDVKLLEGKIIYKLVEEHEEWTKEMEELMKSDEINRLTKPAMIKILPNCIFRQ
KEPAVCGVEVLYGTLKIGSPIMSEDGKKLGYVKEMRDNQQENIKEAKVGMQVPVSIDGNIVLGRNAKENDILYVEVPEPE
ARKLHHEFKDELRGDEKEALSRYMELKQKIENNIFWGM
>Mature_597_residues
ALRCPIVSVLGHVDHGKTSLLDKIRRTRVTQREAGGITQHIGASEIPINTIKKVSKDLLGLFKADLSIPGILVIDTPGHE
AFTSLRKRGGALADIAILVVDINEGFKPQTIEAINILKQCKTPFVVAANKVDRIPGWNSSEGPFILNFNEKNQHPNAMTE
FEIRLYENVIKHLNELGFDADLFSRVKDTTKTINVVPVSAMTGEGVPDLLVIISGLAQRFLEQKLALNVEGYAKGTVLEL
KEEKGLGKTIDAIIYDGIAKTGDFLVVGNPDGVLVSKIKALLKPKELDEMRDPKDKFKPSKQISAATGVKISAPDLDSVI
AGSPLRIVPKNQVEAAKEEVLEEVEEFTILTDDEGIIIKADTMGSLEALANELRKVNAKIKKAEVGDISKKDVIEASSYA
STNPLNGLIISFNTKVLADAKAEIEKSDVKLLEGKIIYKLVEEHEEWTKEMEELMKSDEINRLTKPAMIKILPNCIFRQK
EPAVCGVEVLYGTLKIGSPIMSEDGKKLGYVKEMRDNQQENIKEAKVGMQVPVSIDGNIVLGRNAKENDILYVEVPEPEA
RKLHHEFKDELRGDEKEALSRYMELKQKIENNIFWGM

Specific function: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 [H]

COG id: COG0532

COG function: function code J; Translation initiation factor 2 (IF-2; GTPase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-2 family [H]

Homologues:

Organism=Homo sapiens, GI84043963, Length=582, Percent_Identity=36.7697594501718, Blast_Score=344, Evalue=1e-94,
Organism=Homo sapiens, GI53729339, Length=266, Percent_Identity=34.9624060150376, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI53729337, Length=266, Percent_Identity=34.9624060150376, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1789559, Length=458, Percent_Identity=31.0043668122271, Blast_Score=141, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI212656558, Length=565, Percent_Identity=36.4601769911504, Blast_Score=344, Evalue=8e-95,
Organism=Caenorhabditis elegans, GI71994658, Length=274, Percent_Identity=31.021897810219, Blast_Score=118, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6319282, Length=570, Percent_Identity=36.140350877193, Blast_Score=334, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6324550, Length=480, Percent_Identity=28.3333333333333, Blast_Score=130, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24656849, Length=580, Percent_Identity=37.5862068965517, Blast_Score=351, Evalue=7e-97,
Organism=Drosophila melanogaster, GI28572034, Length=266, Percent_Identity=31.5789473684211, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI160714833, Length=87, Percent_Identity=44.8275862068966, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: 1150 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR004544
- InterPro:   IPR015760
- InterPro:   IPR023115
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2; PF11987 IF-2 [H]

EC number: NA

Molecular weight: Translated: 66154; Mature: 66023

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRCPIVSVLGHVDHGKTSLLDKIRRTRVTQREAGGITQHIGASEIPINTIKKVSKDLL
CCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHH
GLFKADLSIPGILVIDTPGHEAFTSLRKRGGALADIAILVVDINEGFKPQTIEAINILKQ
HHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHH
CKTPFVVAANKVDRIPGWNSSEGPFILNFNEKNQHPNAMTEFEIRLYENVIKHLNELGFD
CCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
ADLFSRVKDTTKTINVVPVSAMTGEGVPDLLVIISGLAQRFLEQKLALNVEGYAKGTVLE
HHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LKEEKGLGKTIDAIIYDGIAKTGDFLVVGNPDGVLVSKIKALLKPKELDEMRDPKDKFKP
EHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHCCCHHHCCC
SKQISAATGVKISAPDLDSVIAGSPLRIVPKNQVEAAKEEVLEEVEEFTILTDDEGIIIK
CHHHHHHCCCEEECCCCHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCEEEECCCCEEEE
ADTMGSLEALANELRKVNAKIKKAEVGDISKKDVIEASSYASTNPLNGLIISFNTKVLAD
ECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCEEEEC
AKAEIEKSDVKLLEGKIIYKLVEEHEEWTKEMEELMKSDEINRLTKPAMIKILPNCIFRQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
KEPAVCGVEVLYGTLKIGSPIMSEDGKKLGYVKEMRDNQQENIKEAKVGMQVPVSIDGNI
CCCCHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHCCHHHHHHHHHCCCEEEEEECCCE
VLGRNAKENDILYVEVPEPEARKLHHEFKDELRGDEKEALSRYMELKQKIENNIFWGM
EECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ALRCPIVSVLGHVDHGKTSLLDKIRRTRVTQREAGGITQHIGASEIPINTIKKVSKDLL
CCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHH
GLFKADLSIPGILVIDTPGHEAFTSLRKRGGALADIAILVVDINEGFKPQTIEAINILKQ
HHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHH
CKTPFVVAANKVDRIPGWNSSEGPFILNFNEKNQHPNAMTEFEIRLYENVIKHLNELGFD
CCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
ADLFSRVKDTTKTINVVPVSAMTGEGVPDLLVIISGLAQRFLEQKLALNVEGYAKGTVLE
HHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LKEEKGLGKTIDAIIYDGIAKTGDFLVVGNPDGVLVSKIKALLKPKELDEMRDPKDKFKP
EHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHCCCHHHCCC
SKQISAATGVKISAPDLDSVIAGSPLRIVPKNQVEAAKEEVLEEVEEFTILTDDEGIIIK
CHHHHHHCCCEEECCCCHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCEEEECCCCEEEE
ADTMGSLEALANELRKVNAKIKKAEVGDISKKDVIEASSYASTNPLNGLIISFNTKVLAD
ECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCEEEEC
AKAEIEKSDVKLLEGKIIYKLVEEHEEWTKEMEELMKSDEINRLTKPAMIKILPNCIFRQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
KEPAVCGVEVLYGTLKIGSPIMSEDGKKLGYVKEMRDNQQENIKEAKVGMQVPVSIDGNI
CCCCHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHCCHHHHHHHHHCCCEEEEEECCCE
VLGRNAKENDILYVEVPEPEARKLHHEFKDELRGDEKEALSRYMELKQKIENNIFWGM
EECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA