Click here to switch to the map view.

The map label for this gene is hypE [C]

Identifier: 45357837

GI number: 45357837

Start: 273244

End: 274248

Strand: Direct

Name: hypE [C]

Synonym: MMP0274

Alternate gene names: 45357837

Gene position: 273244-274248 (Clockwise)

Preceding gene: 45357832

Following gene: 45357838

Centisome position: 16.45

GC content: 37.41

Gene sequence:

>1005_bases
ATGAATATTACACGAATGCATGGTGCTGGCGGAACCGTAATGCAAAAGTTAATTAAGGAAACAATACTCGGTAACTTAGA
AAATACAAAAATTGAGGGCGGAATTGGTCTTGAATCTCTTGATGATGCTTCAACTATACCTATTGGGGACAAAGAAATAG
TTTTTACTGTTGATGGACATACTGTGCATCCAATATTTTTCCCAGGCGGCGATATCGGGAGAATTTCAGTATGTGGAACA
GTAAACGATCTTTCAGTAATGGGGGCAAAACCTGTTGCACTTTCTCTTTCGATAGTCCTTCCAGAAGGATTTGATATTGA
AAAACTCGATAAAATAATGAAGTCAATAAATGAAGCCTGCAAAGAAGCAGGTGTTGCAATAATTACCGGGGATACAAAAG
TTTCAAATGTTGATGATATAATCATTTCATCTGCAGGTATAGGAATTGTTGATTCTGGCAAAGCTGTAAGGGATTGCGGA
ATGAAAGAAGGGGATGTAATAATCGTGAGCGGAAATATCGGGGAGCACGGCCTTACAATACTTCTTTCAAGAGAAGGATT
TGAATTTGAATCAGAATTAAAATCAGACGTAGCTCCGGTAAATGGTCTTGTTCAGAGTGTTTTAAATGCAGGATTTGAAA
TTAATGCAATGAAAGACCCGACAAGAGGCGGTCTTGCAGATTCTTTAAATGAAATGGCAGAAAAAAGTGATTTGGGAATA
TTAATTCATGAAGACAAAATCCCGATAAGTGATGAAGTTCAGGCTATTGGCGAAGCTCTTGGAATTGACCCTTTAACAGT
TGCAAATGAGGGAAAAGTTGTAATGTCAGTAAAAGAAAAAGATTCAGAAAAAATACTTGAAATATTAACGGCACATCCTC
TTGGAAAAAACGCTAAAATTATTGGAAATGTGACATCTGAACACAAGGGCGTTTTAATGGAAACAATTGTTGGAAAAAGA
ATTGTTGACACGCCAATGGGCGACCCAATACCAAGAGTCTGCTAA

Upstream 100 bases:

>100_bases
ATTTAATTTACAATAAGAAATATCGTGCATTAAAACAATATCGCAACCAATAAAAAATAAAATGACTAATTATCAGTAGT
CTAAATTTGGAGTTGATCGC

Downstream 100 bases:

>100_bases
AAATTTTTGAAATATCCAAAAATCCAAAACTTACTTTTTTTATATTTAAAATTCGGCTTTTTTCAAACATCTAAATGATT
ATTCTTTTATCACACGATTA

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MNITRMHGAGGTVMQKLIKETILGNLENTKIEGGIGLESLDDASTIPIGDKEIVFTVDGHTVHPIFFPGGDIGRISVCGT
VNDLSVMGAKPVALSLSIVLPEGFDIEKLDKIMKSINEACKEAGVAIITGDTKVSNVDDIIISSAGIGIVDSGKAVRDCG
MKEGDVIIVSGNIGEHGLTILLSREGFEFESELKSDVAPVNGLVQSVLNAGFEINAMKDPTRGGLADSLNEMAEKSDLGI
LIHEDKIPISDEVQAIGEALGIDPLTVANEGKVVMSVKEKDSEKILEILTAHPLGKNAKIIGNVTSEHKGVLMETIVGKR
IVDTPMGDPIPRVC

Sequences:

>Translated_334_residues
MNITRMHGAGGTVMQKLIKETILGNLENTKIEGGIGLESLDDASTIPIGDKEIVFTVDGHTVHPIFFPGGDIGRISVCGT
VNDLSVMGAKPVALSLSIVLPEGFDIEKLDKIMKSINEACKEAGVAIITGDTKVSNVDDIIISSAGIGIVDSGKAVRDCG
MKEGDVIIVSGNIGEHGLTILLSREGFEFESELKSDVAPVNGLVQSVLNAGFEINAMKDPTRGGLADSLNEMAEKSDLGI
LIHEDKIPISDEVQAIGEALGIDPLTVANEGKVVMSVKEKDSEKILEILTAHPLGKNAKIIGNVTSEHKGVLMETIVGKR
IVDTPMGDPIPRVC
>Mature_334_residues
MNITRMHGAGGTVMQKLIKETILGNLENTKIEGGIGLESLDDASTIPIGDKEIVFTVDGHTVHPIFFPGGDIGRISVCGT
VNDLSVMGAKPVALSLSIVLPEGFDIEKLDKIMKSINEACKEAGVAIITGDTKVSNVDDIIISSAGIGIVDSGKAVRDCG
MKEGDVIIVSGNIGEHGLTILLSREGFEFESELKSDVAPVNGLVQSVLNAGFEINAMKDPTRGGLADSLNEMAEKSDLGI
LIHEDKIPISDEVQAIGEALGIDPLTVANEGKVVMSVKEKDSEKILEILTAHPLGKNAKIIGNVTSEHKGVLMETIVGKR
IVDTPMGDPIPRVC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=38.8724035608309, Blast_Score=241, Evalue=7e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35179; Mature: 35179

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITRMHGAGGTVMQKLIKETILGNLENTKIEGGIGLESLDDASTIPIGDKEIVFTVDGH
CCCEEECCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEECCC
TVHPIFFPGGDIGRISVCGTVNDLSVMGAKPVALSLSIVLPEGFDIEKLDKIMKSINEAC
EEEEEEECCCCCCEEEEEECCCCHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHH
KEAGVAIITGDTKVSNVDDIIISSAGIGIVDSGKAVRDCGMKEGDVIIVSGNIGEHGLTI
HHCCEEEEECCCCCCCCCCEEEECCCCCEEECCCHHHHCCCCCCCEEEEECCCCCCCEEE
LLSREGFEFESELKSDVAPVNGLVQSVLNAGFEINAMKDPTRGGLADSLNEMAEKSDLGI
EEECCCCCHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHCCCEE
LIHEDKIPISDEVQAIGEALGIDPLTVANEGKVVMSVKEKDSEKILEILTAHPLGKNAKI
EEECCCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCHHHHHHHHHCCCCCCCCEE
IGNVTSEHKGVLMETIVGKRIVDTPMGDPIPRVC
EECCCCCCCCHHHHHHHCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MNITRMHGAGGTVMQKLIKETILGNLENTKIEGGIGLESLDDASTIPIGDKEIVFTVDGH
CCCEEECCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEECCC
TVHPIFFPGGDIGRISVCGTVNDLSVMGAKPVALSLSIVLPEGFDIEKLDKIMKSINEAC
EEEEEEECCCCCCEEEEEECCCCHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHH
KEAGVAIITGDTKVSNVDDIIISSAGIGIVDSGKAVRDCGMKEGDVIIVSGNIGEHGLTI
HHCCEEEEECCCCCCCCCCEEEECCCCCEEECCCHHHHCCCCCCCEEEEECCCCCCCEEE
LLSREGFEFESELKSDVAPVNGLVQSVLNAGFEINAMKDPTRGGLADSLNEMAEKSDLGI
EEECCCCCHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHCCCEE
LIHEDKIPISDEVQAIGEALGIDPLTVANEGKVVMSVKEKDSEKILEILTAHPLGKNAKI
EEECCCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCHHHHHHHHHCCCCCCCCEE
IGNVTSEHKGVLMETIVGKRIVDTPMGDPIPRVC
EECCCCCCCCHHHHHHHCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]