Click here to switch to the map view.

The map label for this gene is amtB [C]

Identifier: 45357631

GI number: 45357631

Start: 79353

End: 80588

Strand: Direct

Name: amtB [C]

Synonym: MMP0068

Alternate gene names: 45357631

Gene position: 79353-80588 (Clockwise)

Preceding gene: 45357630

Following gene: 45357632

Centisome position: 4.78

GC content: 40.37

Gene sequence:

>1236_bases
ATGGTGACGGCAGATTTATTCAATAACCCTACAAATATTATGGATGCGTTAAATACGCTTGCAAACTCAAGCGATGTAAT
GTTTTTAATTTTTACTGGTGCTTTTATTTTTATAATGCACCTTGGATTCGCAATGCTCGAAGGCGGTCAGGTTCGAGAAA
AGAACGTGAACAACGCAATGATGAAGAACATGGGCGACTGGATCATTGGATGTATTTCCTGGCTTTTAGTTGGTTCAGTA
ATTGCTAGAACATTAAACCCTGCAGATTTCTTTATTTGGTGGGGAAAAATTGCAAGTGCAACACCTTTCCTTACAAATAA
TGGATTGGAACTTGCAAACTGGTTTTTAGGACTTGTATTTGCGGCAACCGCGGCAACTATCGTTGCAGGGGGAATTGCAG
AGAGAATCAAGTTTAAATCCTATATTTTAATTTCAATCGTTATAACGGCTTTGTTGTACCCATTCTTTAGTTATTTGGGG
CCTTGGGGTGCAGGAGTAATTCCATTCCACGACTATGCGGGAAGCTTAATGGTTCACGGTGTTGGCGGATTTTTGGCACT
TGGCCTAATTGCAGCAATCGGTCCAAGATTTGGCAGATTTGTAAATAAAAAAGCAATAACAATTCCTGGACACAACATCC
CAATGTCGATTTTAGGTGCATACATTCTTGCATTTGGATGGTATGGATTTAACGTTGGAAGTTCACTTGCATTGAGTGAT
ATTTCAGGACTTGTATGTGCAACAACAACACTTGCAATGGCAGGGGGAGGTCTTGGAGGATGTTTATTCTCTAAAAACGA
TGTGTTATATACTGCAAACGGACTTTTGGCAGGAACTGTTGCAATCTGTGCAGGAACTGATATTGTAAGCCCGCTTGGAG
CATTGATAATTGGATTTATTGCAGGATCCCAGGTCCCATTAATATTTAAAATTGTTGAAAAAATGGGATTGGACGATGTA
TGCGGTGTAATTCCAGTACATGCAACATCTGGAGCCCTTGGTGCAATTTTGGCAGGGATATTTGGAATGACTGCATTTGG
CGGTGTTGGTGGAGTCAGCCTTACCGAACAGATAATTGCAACATTAATTTGTGCAGTTTATGGTACTGGTGCAGGATTTA
TTCTCGGAAAACTTGTTGGGGCAGTTACTGGCGGTTTAAGAGTTAAAGAATCTGAAGAAAAAGCAGGACTTGATATTTCA
ATCCACAAACTCCCGGCATACCCTAAAGAAAACTAA

Upstream 100 bases:

>100_bases
AAAATCTTCGTAATTCCGGTCGAAGACGTATGTCGTGTAAGAACTGGTGAAATGGGTCCAGATGCTATATAATATTATTA
AATTTTAATGGTGCGTAAAT

Downstream 100 bases:

>100_bases
ATATTAACTTTTATTTTTTTTAGAAATTTATTTTTATATTTTAAAATCAAATTATTTTTTATGAAAACATTCAATGAACA
GTGCTACGACCTTATAATGC

Product: ammonium transporter

Products: NH3 [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MVTADLFNNPTNIMDALNTLANSSDVMFLIFTGAFIFIMHLGFAMLEGGQVREKNVNNAMMKNMGDWIIGCISWLLVGSV
IARTLNPADFFIWWGKIASATPFLTNNGLELANWFLGLVFAATAATIVAGGIAERIKFKSYILISIVITALLYPFFSYLG
PWGAGVIPFHDYAGSLMVHGVGGFLALGLIAAIGPRFGRFVNKKAITIPGHNIPMSILGAYILAFGWYGFNVGSSLALSD
ISGLVCATTTLAMAGGGLGGCLFSKNDVLYTANGLLAGTVAICAGTDIVSPLGALIIGFIAGSQVPLIFKIVEKMGLDDV
CGVIPVHATSGALGAILAGIFGMTAFGGVGGVSLTEQIIATLICAVYGTGAGFILGKLVGAVTGGLRVKESEEKAGLDIS
IHKLPAYPKEN

Sequences:

>Translated_411_residues
MVTADLFNNPTNIMDALNTLANSSDVMFLIFTGAFIFIMHLGFAMLEGGQVREKNVNNAMMKNMGDWIIGCISWLLVGSV
IARTLNPADFFIWWGKIASATPFLTNNGLELANWFLGLVFAATAATIVAGGIAERIKFKSYILISIVITALLYPFFSYLG
PWGAGVIPFHDYAGSLMVHGVGGFLALGLIAAIGPRFGRFVNKKAITIPGHNIPMSILGAYILAFGWYGFNVGSSLALSD
ISGLVCATTTLAMAGGGLGGCLFSKNDVLYTANGLLAGTVAICAGTDIVSPLGALIIGFIAGSQVPLIFKIVEKMGLDDV
CGVIPVHATSGALGAILAGIFGMTAFGGVGGVSLTEQIIATLICAVYGTGAGFILGKLVGAVTGGLRVKESEEKAGLDIS
IHKLPAYPKEN
>Mature_411_residues
MVTADLFNNPTNIMDALNTLANSSDVMFLIFTGAFIFIMHLGFAMLEGGQVREKNVNNAMMKNMGDWIIGCISWLLVGSV
IARTLNPADFFIWWGKIASATPFLTNNGLELANWFLGLVFAATAATIVAGGIAERIKFKSYILISIVITALLYPFFSYLG
PWGAGVIPFHDYAGSLMVHGVGGFLALGLIAAIGPRFGRFVNKKAITIPGHNIPMSILGAYILAFGWYGFNVGSSLALSD
ISGLVCATTTLAMAGGGLGGCLFSKNDVLYTANGLLAGTVAICAGTDIVSPLGALIIGFIAGSQVPLIFKIVEKMGLDDV
CGVIPVHATSGALGAILAGIFGMTAFGGVGGVSLTEQIIATLICAVYGTGAGFILGKLVGAVTGGLRVKESEEKAGLDIS
IHKLPAYPKEN

Specific function: Involved In The Uptake Of Ammonia (Probable). [C]

COG id: COG0004

COG function: function code P; Ammonia permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ammonium transporter (TC 2.A.49) family [H]

Homologues:

Organism=Escherichia coli, GI1786656, Length=426, Percent_Identity=30.9859154929577, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17550182, Length=437, Percent_Identity=32.0366132723112, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17550180, Length=459, Percent_Identity=30.0653594771242, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI32564042, Length=421, Percent_Identity=30.166270783848, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI133931100, Length=449, Percent_Identity=28.0623608017817, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6325396, Length=418, Percent_Identity=27.0334928229665, Blast_Score=93, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6321559, Length=410, Percent_Identity=25.1219512195122, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324187, Length=344, Percent_Identity=24.1279069767442, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161078314, Length=412, Percent_Identity=30.0970873786408, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001905
- InterPro:   IPR018047 [H]

Pfam domain/function: PF00909 Ammonium_transp [H]

EC number: NA

Molecular weight: Translated: 42788; Mature: 42788

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS01219 AMMONIUM_TRANSP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTADLFNNPTNIMDALNTLANSSDVMFLIFTGAFIFIMHLGFAMLEGGQVREKNVNNAM
CEECHHCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
MKNMGDWIIGCISWLLVGSVIARTLNPADFFIWWGKIASATPFLTNNGLELANWFLGLVF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHCCCCCCEECCCHHHHHHHHHHHH
AATAATIVAGGIAERIKFKSYILISIVITALLYPFFSYLGPWGAGVIPFHDYAGSLMVHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEC
VGGFLALGLIAAIGPRFGRFVNKKAITIPGHNIPMSILGAYILAFGWYGFNVGSSLALSD
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
ISGLVCATTTLAMAGGGLGGCLFSKNDVLYTANGLLAGTVAICAGTDIVSPLGALIIGFI
HHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHH
AGSQVPLIFKIVEKMGLDDVCGVIPVHATSGALGAILAGIFGMTAFGGVGGVSLTEQIIA
CCCCCHHHHHHHHHCCCCHHHCCEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TLICAVYGTGAGFILGKLVGAVTGGLRVKESEEKAGLDISIHKLPAYPKEN
HHHHHHHCCCHHHHHHHHHHHHHCCCEEECCHHHCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MVTADLFNNPTNIMDALNTLANSSDVMFLIFTGAFIFIMHLGFAMLEGGQVREKNVNNAM
CEECHHCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
MKNMGDWIIGCISWLLVGSVIARTLNPADFFIWWGKIASATPFLTNNGLELANWFLGLVF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHCCCCCCEECCCHHHHHHHHHHHH
AATAATIVAGGIAERIKFKSYILISIVITALLYPFFSYLGPWGAGVIPFHDYAGSLMVHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEC
VGGFLALGLIAAIGPRFGRFVNKKAITIPGHNIPMSILGAYILAFGWYGFNVGSSLALSD
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
ISGLVCATTTLAMAGGGLGGCLFSKNDVLYTANGLLAGTVAICAGTDIVSPLGALIIGFI
HHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHH
AGSQVPLIFKIVEKMGLDDVCGVIPVHATSGALGAILAGIFGMTAFGGVGGVSLTEQIIA
CCCCCHHHHHHHHHCCCCHHHCCEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TLICAVYGTGAGFILGKLVGAVTGGLRVKESEEKAGLDISIHKLPAYPKEN
HHHHHHHCCCHHHHHHHHHHHHHCCCEEECCHHHCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NH3 [Periplasm] [C]

Specific reaction: NH3 [Periplasm] = NH3 [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]