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The map label for this gene is ribH [H]

Identifier: 45357613

GI number: 45357613

Start: 66371

End: 66784

Strand: Direct

Name: ribH [H]

Synonym: MMP0050

Alternate gene names: 45357613

Gene position: 66371-66784 (Clockwise)

Preceding gene: 45357612

Following gene: 45357614

Centisome position: 4.0

GC content: 36.71

Gene sequence:

>414_bases
ATGGTCAACTTAGGATTTGTTATCGCAGAATTCAACAGGGATTTAACATTCATGATGGAAAAAATGGCAGAAGAACATGC
TGAATTTTTAGGTGCAAATGTTTCCCACAAAATAATGGTTCCAGGATCATTTGACATGCCTCTTGCAATCAAAACACTTC
TTCAAAAAGACGACATCGATGCAATTGTTACAATTGGATGCGTTATCGAAGGAGATACTGAACACGATGAAATTGTAGTT
CAAAACGCGGCAAGAAAAATTGCAGACTTATCTTTAGACTTTGGAAAACCAGTTGCACTTGGAATTGCGGGACCTGGAAT
GACAAGAATGCAGGCTGAAGATAGAATTGATTACGGTAAAAACGCAGTAGAAGCTGCTGTTAAAATGGTAAAAAGACTTA
AAGAAATTCAATAA

Upstream 100 bases:

>100_bases
TTCCATAAAAGAGAATGCAAAAAACTATCTTGAACTATCAAAAAACTTATAATGTTTAAAAATCAATGAGACTATTATTG
TAAATCAATAGGGTGAAAAA

Downstream 100 bases:

>100_bases
TTTAAAATTAAATTTATAAATCTTTTTTAGTGATTTTATGAATGTTTTAAAAGAAGTATATGCTACGATCGAAAAAAGAA
TCGAAGAAAAACCCGAAGGC

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MVNLGFVIAEFNRDLTFMMEKMAEEHAEFLGANVSHKIMVPGSFDMPLAIKTLLQKDDIDAIVTIGCVIEGDTEHDEIVV
QNAARKIADLSLDFGKPVALGIAGPGMTRMQAEDRIDYGKNAVEAAVKMVKRLKEIQ

Sequences:

>Translated_137_residues
MVNLGFVIAEFNRDLTFMMEKMAEEHAEFLGANVSHKIMVPGSFDMPLAIKTLLQKDDIDAIVTIGCVIEGDTEHDEIVV
QNAARKIADLSLDFGKPVALGIAGPGMTRMQAEDRIDYGKNAVEAAVKMVKRLKEIQ
>Mature_137_residues
MVNLGFVIAEFNRDLTFMMEKMAEEHAEFLGANVSHKIMVPGSFDMPLAIKTLLQKDDIDAIVTIGCVIEGDTEHDEIVV
QNAARKIADLSLDFGKPVALGIAGPGMTRMQAEDRIDYGKNAVEAAVKMVKRLKEIQ

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 15063; Mature: 15063

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNLGFVIAEFNRDLTFMMEKMAEEHAEFLGANVSHKIMVPGSFDMPLAIKTLLQKDDID
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHCCCCCC
AIVTIGCVIEGDTEHDEIVVQNAARKIADLSLDFGKPVALGIAGPGMTRMQAEDRIDYGK
EEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCC
NAVEAAVKMVKRLKEIQ
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVNLGFVIAEFNRDLTFMMEKMAEEHAEFLGANVSHKIMVPGSFDMPLAIKTLLQKDDID
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHCCCCCC
AIVTIGCVIEGDTEHDEIVVQNAARKIADLSLDFGKPVALGIAGPGMTRMQAEDRIDYGK
EEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCC
NAVEAAVKMVKRLKEIQ
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA