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The map label for this gene is 45357593

Identifier: 45357593

GI number: 45357593

Start: 45639

End: 47657

Strand: Direct

Name: 45357593

Synonym: MMP0030

Alternate gene names: NA

Gene position: 45639-47657 (Clockwise)

Preceding gene: 45357591

Following gene: 45357594

Centisome position: 2.75

GC content: 32.54

Gene sequence:

>2019_bases
ATGGATGATAAACAGATTCAAAATATTCGACCACGACTTACAGAATGCTTAAAAACGCTAAATTTTCAAGATATTATCTC
TGAAAAAAAGAAAGTAGCTGTTGATATAGATAATATCTATAAACACGGGGTAATTGACTTTATAGAGTTTTTAGAAGAAT
TTCCAAAAGAAGGAATAGAACTCCTTGAAGAGTGCTACAGGGATGCATACTATTCAATAAAAACGGAAAAGCCCGATATT
GTAATTACTGTAAAAAATATACCTGAAGAATTTAATAAATCTGAAAAAAAGCAAAATTACACTATCGAAGATATTAAAAG
CGGCACTCTTGGAAAATTGATTGAATTTGAAGGAATAATTGTTATCGCAACAAAAATAAAATCAGCCCTAAAAAAGGCAA
CTTACGTATGCACACAATGTGGCGAAAAAAAAATACAAGAAGTTGAAAATCCATTTGAAGCTTATTTTGAACCACCATGT
CCAAAATGTGCTCAAAATATGACTTTAATTGAGGACGAATCTGAATATATTGATTTTCAAGAAATTAAAGTTCAACAGCC
CCTTGATTCCATGGGCGACCCTGAAGAGCCGCCAAAATATATTACTGTATTTTTAGAACACAGCCCTGGAATTTATTGTG
GGCGTGTAAAAGTTACAGGAATTCCAATAAAAAACCAGAAAAACAAAAATATCCCGATTTATGATATTTACGTTAAAGGA
ATTAATTGTGAAGTTTTAGAAGATAAAATTGAAGCAAATTTAAATGAAGAAGATATCAAAAATATCGAAAAAGTTGGAAA
AAATCCAAAAGTAATAGATATATTATCTGAAAGGATGATTCCTGAAATTAAAGGTTATGAAATTATCAAAAAAGCGATAT
TTTTACAGCAAGTTAAAGGGGTTAAAAAGGGAAACAAAAGAGCTGACAGCCACTTGCTTTTAATTACGGACCCAGGTATT
GGAAAATCAGTTATGCTTAGAAAAATTGCGGAAATTCCCGGAAATTTGTACGGGTCAGCCACTACTGCATCAGGTGTTGG
TTTAACTGCCGCAGTTATTCGTGAAAAAACCGAAATTGGAGACGATACATGGGTTATTAAACCCGGACTTTTGGTTAAAG
CAAATAAAGGAACTGCATGTATTGATGAGCTTACAGTTAATCGGGACCTTCAAACTTTTGTTCTTGAAGCTATGGAATCT
CAAACAATACACGTTAGTAAAGGTGGAATCAATGCAAAATTACCATCAGAATGTGCAATTATTGCAGCATGTAACCCAAG
ATGGGGTAGGTTTGATCCAAATGTCTCGATTCCTGAACAGATAAATATTCCTGCACCTATGCTAAGCAGGTTTGATTTAA
TATTCCCGATAAAAGATGAAGCAGATCGATCAAAAGATAAAGACATTGCACAACATATTATCAATGTTCATAGAGCGTAT
TTAAGTAAAGAAGTTTCGAAAAATATGAAACTCGACCATATTATAGTCGATGATGTCTTGATTGATAGGGATTTTGTAAT
AAAATATATAGAATATGCAAAAACTAAATCACCGATAATTTCAGAAAGTGCTGAAAAACTATTAACTGAATTTTATTTAA
ACATGAGAAAAGGTTCAGTTCAAATTACTGCAAGACAGCTTGAAGCGGCAATCCGTATTGCAGAAGCACATGCAAAAGCA
AAATTAAAAGATGTTGTTGACGAAGAAGACGCAAATGAAGCCATTTCAATAATTACTGAATCTTTAAAGGAAACTGCATA
TGATCCTGAAACCGGACAGTTTGATGTCGATAAAATTTCAGGAGTTGGAAAAAAAGATAGAAGTAAGATGATGGGAGTAT
ATGATTTAATAAAAGCACTTGCTGAAAAAAGCGACAACGATCTTGTAATAATTGATGAAATCGTAGAAGCTGGAAAATCA
AAAGGAATTGATGAAGAACATATCTTACTTTCAATTAAAAAGCTTAAGAGTAATGGGGACATTGATGAACCCAAGACTGG
AAAATTCAGGATAATTTAA

Upstream 100 bases:

>100_bases
TTGATAAATTTTAACTTTTGGATAACTCATTAAAACATTTCATAATTATTATATAGATCTGAAAACATATATGAAAGGTA
CCAGAAAATTTGTGAAAATA

Downstream 100 bases:

>100_bases
AAATTTGTGAAAATCATGGAAATTATTTACAATAAACCCGAAATTTATGCAACAAATGATATCTGGATTCAGCCTGTTAG
CAGGAGCTCTGTTTTAGAGT

Product: MCM family DNA replication protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MDDKQIQNIRPRLTECLKTLNFQDIISEKKKVAVDIDNIYKHGVIDFIEFLEEFPKEGIELLEECYRDAYYSIKTEKPDI
VITVKNIPEEFNKSEKKQNYTIEDIKSGTLGKLIEFEGIIVIATKIKSALKKATYVCTQCGEKKIQEVENPFEAYFEPPC
PKCAQNMTLIEDESEYIDFQEIKVQQPLDSMGDPEEPPKYITVFLEHSPGIYCGRVKVTGIPIKNQKNKNIPIYDIYVKG
INCEVLEDKIEANLNEEDIKNIEKVGKNPKVIDILSERMIPEIKGYEIIKKAIFLQQVKGVKKGNKRADSHLLLITDPGI
GKSVMLRKIAEIPGNLYGSATTASGVGLTAAVIREKTEIGDDTWVIKPGLLVKANKGTACIDELTVNRDLQTFVLEAMES
QTIHVSKGGINAKLPSECAIIAACNPRWGRFDPNVSIPEQINIPAPMLSRFDLIFPIKDEADRSKDKDIAQHIINVHRAY
LSKEVSKNMKLDHIIVDDVLIDRDFVIKYIEYAKTKSPIISESAEKLLTEFYLNMRKGSVQITARQLEAAIRIAEAHAKA
KLKDVVDEEDANEAISIITESLKETAYDPETGQFDVDKISGVGKKDRSKMMGVYDLIKALAEKSDNDLVIIDEIVEAGKS
KGIDEEHILLSIKKLKSNGDIDEPKTGKFRII

Sequences:

>Translated_672_residues
MDDKQIQNIRPRLTECLKTLNFQDIISEKKKVAVDIDNIYKHGVIDFIEFLEEFPKEGIELLEECYRDAYYSIKTEKPDI
VITVKNIPEEFNKSEKKQNYTIEDIKSGTLGKLIEFEGIIVIATKIKSALKKATYVCTQCGEKKIQEVENPFEAYFEPPC
PKCAQNMTLIEDESEYIDFQEIKVQQPLDSMGDPEEPPKYITVFLEHSPGIYCGRVKVTGIPIKNQKNKNIPIYDIYVKG
INCEVLEDKIEANLNEEDIKNIEKVGKNPKVIDILSERMIPEIKGYEIIKKAIFLQQVKGVKKGNKRADSHLLLITDPGI
GKSVMLRKIAEIPGNLYGSATTASGVGLTAAVIREKTEIGDDTWVIKPGLLVKANKGTACIDELTVNRDLQTFVLEAMES
QTIHVSKGGINAKLPSECAIIAACNPRWGRFDPNVSIPEQINIPAPMLSRFDLIFPIKDEADRSKDKDIAQHIINVHRAY
LSKEVSKNMKLDHIIVDDVLIDRDFVIKYIEYAKTKSPIISESAEKLLTEFYLNMRKGSVQITARQLEAAIRIAEAHAKA
KLKDVVDEEDANEAISIITESLKETAYDPETGQFDVDKISGVGKKDRSKMMGVYDLIKALAEKSDNDLVIIDEIVEAGKS
KGIDEEHILLSIKKLKSNGDIDEPKTGKFRII
>Mature_672_residues
MDDKQIQNIRPRLTECLKTLNFQDIISEKKKVAVDIDNIYKHGVIDFIEFLEEFPKEGIELLEECYRDAYYSIKTEKPDI
VITVKNIPEEFNKSEKKQNYTIEDIKSGTLGKLIEFEGIIVIATKIKSALKKATYVCTQCGEKKIQEVENPFEAYFEPPC
PKCAQNMTLIEDESEYIDFQEIKVQQPLDSMGDPEEPPKYITVFLEHSPGIYCGRVKVTGIPIKNQKNKNIPIYDIYVKG
INCEVLEDKIEANLNEEDIKNIEKVGKNPKVIDILSERMIPEIKGYEIIKKAIFLQQVKGVKKGNKRADSHLLLITDPGI
GKSVMLRKIAEIPGNLYGSATTASGVGLTAAVIREKTEIGDDTWVIKPGLLVKANKGTACIDELTVNRDLQTFVLEAMES
QTIHVSKGGINAKLPSECAIIAACNPRWGRFDPNVSIPEQINIPAPMLSRFDLIFPIKDEADRSKDKDIAQHIINVHRAY
LSKEVSKNMKLDHIIVDDVLIDRDFVIKYIEYAKTKSPIISESAEKLLTEFYLNMRKGSVQITARQLEAAIRIAEAHAKA
KLKDVVDEEDANEAISIITESLKETAYDPETGQFDVDKISGVGKKDRSKMMGVYDLIKALAEKSDNDLVIIDEIVEAGKS
KGIDEEHILLSIKKLKSNGDIDEPKTGKFRII

Specific function: Unknown

COG id: COG1241

COG function: function code L; Predicted ATPase involved in replication control, Cdc46/Mcm family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MCM domain [H]

Homologues:

Organism=Homo sapiens, GI33469919, Length=610, Percent_Identity=29.672131147541, Blast_Score=225, Evalue=1e-58,
Organism=Homo sapiens, GI33469917, Length=610, Percent_Identity=29.672131147541, Blast_Score=225, Evalue=1e-58,
Organism=Homo sapiens, GI33469968, Length=530, Percent_Identity=31.3207547169811, Blast_Score=223, Evalue=6e-58,
Organism=Homo sapiens, GI33469922, Length=488, Percent_Identity=32.3770491803279, Blast_Score=206, Evalue=9e-53,
Organism=Homo sapiens, GI23510448, Length=591, Percent_Identity=27.7495769881557, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI33356547, Length=525, Percent_Identity=27.6190476190476, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI19923727, Length=625, Percent_Identity=26.72, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI33469924, Length=612, Percent_Identity=27.4509803921569, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI6631095, Length=392, Percent_Identity=30.1020408163265, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI7427519, Length=630, Percent_Identity=26.8253968253968, Blast_Score=177, Evalue=4e-44,
Organism=Homo sapiens, GI310128402, Length=245, Percent_Identity=31.8367346938775, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI310119838, Length=245, Percent_Identity=31.8367346938775, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI310115110, Length=245, Percent_Identity=31.8367346938775, Blast_Score=115, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17508417, Length=533, Percent_Identity=29.8311444652908, Blast_Score=221, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71997752, Length=518, Percent_Identity=31.4671814671815, Blast_Score=216, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17562702, Length=605, Percent_Identity=27.7685950413223, Blast_Score=214, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17562700, Length=626, Percent_Identity=26.9968051118211, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17554306, Length=612, Percent_Identity=27.9411764705882, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI71997563, Length=562, Percent_Identity=25.9786476868327, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71997571, Length=326, Percent_Identity=31.9018404907975, Blast_Score=150, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6325276, Length=677, Percent_Identity=29.8375184638109, Blast_Score=248, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6319679, Length=578, Percent_Identity=30.1038062283737, Blast_Score=203, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6321237, Length=345, Percent_Identity=33.9130434782609, Blast_Score=183, Evalue=8e-47,
Organism=Saccharomyces cerevisiae, GI6320803, Length=668, Percent_Identity=26.6467065868263, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6323304, Length=470, Percent_Identity=31.9148936170213, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6319448, Length=550, Percent_Identity=25.8181818181818, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI17137242, Length=554, Percent_Identity=30.6859205776173, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI17137132, Length=575, Percent_Identity=29.0434782608696, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24645774, Length=587, Percent_Identity=29.4718909710392, Blast_Score=203, Evalue=4e-52,
Organism=Drosophila melanogaster, GI17530827, Length=662, Percent_Identity=24.6223564954683, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI17647617, Length=531, Percent_Identity=29.3785310734463, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24639835, Length=552, Percent_Identity=27.536231884058, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24647251, Length=568, Percent_Identity=23.2394366197183, Blast_Score=120, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001208
- InterPro:   IPR018525
- InterPro:   IPR008047
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00493 MCM [H]

EC number: NA

Molecular weight: Translated: 75635; Mature: 75635

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00847 MCM_1 ; PS50051 MCM_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDKQIQNIRPRLTECLKTLNFQDIISEKKKVAVDIDNIYKHGVIDFIEFLEEFPKEGIE
CCCHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LLEECYRDAYYSIKTEKPDIVITVKNIPEEFNKSEKKQNYTIEDIKSGTLGKLIEFEGII
HHHHHHHHHHEEEECCCCCEEEEECCCCHHHCHHHHHCCCCHHHHCCCCHHHHEEECCEE
VIATKIKSALKKATYVCTQCGEKKIQEVENPFEAYFEPPCPKCAQNMTLIEDESEYIDFQ
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHCCCEEEECCCHHCCHH
EIKVQQPLDSMGDPEEPPKYITVFLEHSPGIYCGRVKVTGIPIKNQKNKNIPIYDIYVKG
HHEECCCHHHCCCCCCCCCEEEEEEECCCCEEEEEEEEEEECCCCCCCCCCCEEEEEEEC
INCEVLEDKIEANLNEEDIKNIEKVGKNPKVIDILSERMIPEIKGYEIIKKAIFLQQVKG
CCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VKKGNKRADSHLLLITDPGIGKSVMLRKIAEIPGNLYGSATTASGVGLTAAVIREKTEIG
HHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
DDTWVIKPGLLVKANKGTACIDELTVNRDLQTFVLEAMESQTIHVSKGGINAKLPSECAI
CCEEEECCCEEEECCCCCEEHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEE
IAACNPRWGRFDPNVSIPEQINIPAPMLSRFDLIFPIKDEADRSKDKDIAQHIINVHRAY
EEECCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
LSKEVSKNMKLDHIIVDDVLIDRDFVIKYIEYAKTKSPIISESAEKLLTEFYLNMRKGSV
HHHHHHCCCCCCEEEEHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCE
QITARQLEAAIRIAEAHAKAKLKDVVDEEDANEAISIITESLKETAYDPETGQFDVDKIS
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHC
GVGKKDRSKMMGVYDLIKALAEKSDNDLVIIDEIVEAGKSKGIDEEHILLSIKKLKSNGD
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCHHHHHEEHHHHHCCCC
IDEPKTGKFRII
CCCCCCCCEEEC
>Mature Secondary Structure
MDDKQIQNIRPRLTECLKTLNFQDIISEKKKVAVDIDNIYKHGVIDFIEFLEEFPKEGIE
CCCHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LLEECYRDAYYSIKTEKPDIVITVKNIPEEFNKSEKKQNYTIEDIKSGTLGKLIEFEGII
HHHHHHHHHHEEEECCCCCEEEEECCCCHHHCHHHHHCCCCHHHHCCCCHHHHEEECCEE
VIATKIKSALKKATYVCTQCGEKKIQEVENPFEAYFEPPCPKCAQNMTLIEDESEYIDFQ
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHCCCEEEECCCHHCCHH
EIKVQQPLDSMGDPEEPPKYITVFLEHSPGIYCGRVKVTGIPIKNQKNKNIPIYDIYVKG
HHEECCCHHHCCCCCCCCCEEEEEEECCCCEEEEEEEEEEECCCCCCCCCCCEEEEEEEC
INCEVLEDKIEANLNEEDIKNIEKVGKNPKVIDILSERMIPEIKGYEIIKKAIFLQQVKG
CCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VKKGNKRADSHLLLITDPGIGKSVMLRKIAEIPGNLYGSATTASGVGLTAAVIREKTEIG
HHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
DDTWVIKPGLLVKANKGTACIDELTVNRDLQTFVLEAMESQTIHVSKGGINAKLPSECAI
CCEEEECCCEEEECCCCCEEHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEE
IAACNPRWGRFDPNVSIPEQINIPAPMLSRFDLIFPIKDEADRSKDKDIAQHIINVHRAY
EEECCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
LSKEVSKNMKLDHIIVDDVLIDRDFVIKYIEYAKTKSPIISESAEKLLTEFYLNMRKGSV
HHHHHHCCCCCCEEEEHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCE
QITARQLEAAIRIAEAHAKAKLKDVVDEEDANEAISIITESLKETAYDPETGQFDVDKIS
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHC
GVGKKDRSKMMGVYDLIKALAEKSDNDLVIIDEIVEAGKSKGIDEEHILLSIKKLKSNGD
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCHHHHHEEHHHHHCCCC
IDEPKTGKFRII
CCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]