Click here to switch to the map view.

The map label for this gene is argS

Identifier: 42523502

GI number: 42523502

Start: 1935446

End: 1937188

Strand: Direct

Name: argS

Synonym: Bd2027

Alternate gene names: 42523502

Gene position: 1935446-1937188 (Clockwise)

Preceding gene: 42523501

Following gene: 42523503

Centisome position: 51.16

GC content: 49.11

Gene sequence:

>1743_bases
ATGATTAAACACGACTCCATTCGATTGCTTGCGACGAACTTACTTAAAGATGCGATTGGCCGCGCTTATCCGGATTTTTC
TGCTTCTGAAGACGATATTTATAAGGCTTTGGTAAATCCCCCAAAATCAGATCTGGGTGACCTGGCTTTTGGTTGCTTCA
TTTTGGCGAAGGCATTGAAAACTGCTCCTCCACAAGTGGCCACGGCAGTTGCCGCTCAAATGAAAGGGGCCACCGCGGTA
GCGGCGGGTCCTTATATTAATATCCGTTTTGACGAACAAACTCATGGTGAACAGGTGTTGGCGACGATCCTGGATGGCAG
CTATTTCAAAAAGCCGCTGATGGAAAAATCCCCTAAAACCATGATCGAATATTCCCAGCCAAACACGCACAAAGAACTTC
ACGTGGGTCATATGCGCAACCTTTGTTTGGGCGACGCGATTGTTCGCATGCTTCGTTATAGCGGCCGTGAGATCGTTTCT
TCGACCTTCCCGGGCGACATGGGTACGCACGTGGCGAAGTGTCTTTGGTACATGAAAAAACACAATCAAGAGCCAGTGCC
TGAAACTGAAAAAGGCGAATGGCTGGGCCGCATGTATTCCAAGGCCAATTTGCTGTTGGAAGATCAAAACGGCACACCTC
AGGAGGACATCAACCGCCAGGAGCTGACGGCAATCTTGCATCAGTTGGAAGGCAAAACCGGTCCTTATTATGACCTGTGG
TTAGAAACCCGCGAATGGTCCATCGAATTGATGAAAAAGGTCTATGCCTGGGCGGATGTGACTTTTGATGAATGGTACTT
TGAATCTGAAATGGATTCTCCGTCGGCGGCTTGGGTGAAGCAACTGTATGCTGAAGGCAAGCTTGAGATGTCTCAAGGGG
CCATCGGTAAAGATCTGGAGTCTGAGAAATTAGGCTTCTGTATGCTTTTGAAATCCGACGGCACGGGTCTTTACGCGACG
AAAGATTTGTTGTTGGCAAAACACAAGTTTGAAGATGTGAAGATTGAAAAAAGTGTTTATGTCGTCGACATGCGCCAGGC
TTTGCACTTTAAACAGGTCTTCCGCGTTTTGGAAATCCTGGGCTTTGAGCAGGCGAAAAACTGCTTCCACCTTCAGTACA
ACTATGTCGAGCTTCCGGATGGTGCGATGAGTTCCCGTAAGGGCAATATCGTTCCGCTGCGTGAACTGGTTCACCGCATG
GAAGATCACGTGAAGACCACGTACCTGAGTCGCTATAAAGGTGAATGGTCTGAAGAGGATGTTGAGAAGATCGCCGGCCA
AGTGGCCAAAGGTGCTATTTTCTATGGCATGCTTCGTATGGATACGAACAAAAAGATCGTCTTTGATATGAACGAATGGT
TGAAACTGGACGGAGAGTCCGGTCCGTTTGTGCAATATTCTTACGCACGTATTTCCAGTCTGGGGCGCAAGTTCCCGCGC
ACGGCCGGTGCAAAAATTGACTGGAGTCGCCTGAATCACGCTTCTGAAAGACAGCTGATGCAGTCTTTGGGGGGCTTTAA
CACGGCGGTCGCGGCGGCAGCGGAAAACTTCAAGCCTTCAGCGATTTGCACTTATTTGTATGATCTGGCGAAGAGCTTTA
ACGTCTTTTATCACGAGTGCCCGATCGGCACAGAAGCTGACGTGGCAACGCGCGAAGCTCGCCTGGCATTGAGCGAAGCA
GTCGGTTTGACTCTGAAAAATGGTCTGGCGGTTTTGGGTATGCCTGCACCGGAAAAAATGTAG

Upstream 100 bases:

>100_bases
AGGAATTGAAAAAAGACCTGAAATTCCACAGAAATATCAGTATAGTTGTCCTTCTTATTGGTCTGGCTTGGGCTGGCGTA
TTTTTCTTCTGGAAAGGTCT

Downstream 100 bases:

>100_bases
TTTTAGATGAGAAAACAGGCCTCCAAATGAAAATCTGGAGGCCTCCGCTTATACCCCGCATTAACGCTAGTCTTTTTACT
CAATTGGACCCATGATCGTC

Product: hypothetical protein

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MIKHDSIRLLATNLLKDAIGRAYPDFSASEDDIYKALVNPPKSDLGDLAFGCFILAKALKTAPPQVATAVAAQMKGATAV
AAGPYINIRFDEQTHGEQVLATILDGSYFKKPLMEKSPKTMIEYSQPNTHKELHVGHMRNLCLGDAIVRMLRYSGREIVS
STFPGDMGTHVAKCLWYMKKHNQEPVPETEKGEWLGRMYSKANLLLEDQNGTPQEDINRQELTAILHQLEGKTGPYYDLW
LETREWSIELMKKVYAWADVTFDEWYFESEMDSPSAAWVKQLYAEGKLEMSQGAIGKDLESEKLGFCMLLKSDGTGLYAT
KDLLLAKHKFEDVKIEKSVYVVDMRQALHFKQVFRVLEILGFEQAKNCFHLQYNYVELPDGAMSSRKGNIVPLRELVHRM
EDHVKTTYLSRYKGEWSEEDVEKIAGQVAKGAIFYGMLRMDTNKKIVFDMNEWLKLDGESGPFVQYSYARISSLGRKFPR
TAGAKIDWSRLNHASERQLMQSLGGFNTAVAAAAENFKPSAICTYLYDLAKSFNVFYHECPIGTEADVATREARLALSEA
VGLTLKNGLAVLGMPAPEKM

Sequences:

>Translated_580_residues
MIKHDSIRLLATNLLKDAIGRAYPDFSASEDDIYKALVNPPKSDLGDLAFGCFILAKALKTAPPQVATAVAAQMKGATAV
AAGPYINIRFDEQTHGEQVLATILDGSYFKKPLMEKSPKTMIEYSQPNTHKELHVGHMRNLCLGDAIVRMLRYSGREIVS
STFPGDMGTHVAKCLWYMKKHNQEPVPETEKGEWLGRMYSKANLLLEDQNGTPQEDINRQELTAILHQLEGKTGPYYDLW
LETREWSIELMKKVYAWADVTFDEWYFESEMDSPSAAWVKQLYAEGKLEMSQGAIGKDLESEKLGFCMLLKSDGTGLYAT
KDLLLAKHKFEDVKIEKSVYVVDMRQALHFKQVFRVLEILGFEQAKNCFHLQYNYVELPDGAMSSRKGNIVPLRELVHRM
EDHVKTTYLSRYKGEWSEEDVEKIAGQVAKGAIFYGMLRMDTNKKIVFDMNEWLKLDGESGPFVQYSYARISSLGRKFPR
TAGAKIDWSRLNHASERQLMQSLGGFNTAVAAAAENFKPSAICTYLYDLAKSFNVFYHECPIGTEADVATREARLALSEA
VGLTLKNGLAVLGMPAPEKM
>Mature_580_residues
MIKHDSIRLLATNLLKDAIGRAYPDFSASEDDIYKALVNPPKSDLGDLAFGCFILAKALKTAPPQVATAVAAQMKGATAV
AAGPYINIRFDEQTHGEQVLATILDGSYFKKPLMEKSPKTMIEYSQPNTHKELHVGHMRNLCLGDAIVRMLRYSGREIVS
STFPGDMGTHVAKCLWYMKKHNQEPVPETEKGEWLGRMYSKANLLLEDQNGTPQEDINRQELTAILHQLEGKTGPYYDLW
LETREWSIELMKKVYAWADVTFDEWYFESEMDSPSAAWVKQLYAEGKLEMSQGAIGKDLESEKLGFCMLLKSDGTGLYAT
KDLLLAKHKFEDVKIEKSVYVVDMRQALHFKQVFRVLEILGFEQAKNCFHLQYNYVELPDGAMSSRKGNIVPLRELVHRM
EDHVKTTYLSRYKGEWSEEDVEKIAGQVAKGAIFYGMLRMDTNKKIVFDMNEWLKLDGESGPFVQYSYARISSLGRKFPR
TAGAKIDWSRLNHASERQLMQSLGGFNTAVAAAAENFKPSAICTYLYDLAKSFNVFYHECPIGTEADVATREARLALSEA
VGLTLKNGLAVLGMPAPEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=517, Percent_Identity=26.4990328820116, Blast_Score=159, Evalue=9e-39,
Organism=Homo sapiens, GI15149476, Length=609, Percent_Identity=23.1527093596059, Blast_Score=139, Evalue=7e-33,
Organism=Escherichia coli, GI1788184, Length=565, Percent_Identity=28.141592920354, Blast_Score=189, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI71985061, Length=614, Percent_Identity=22.1498371335505, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17532153, Length=489, Percent_Identity=24.7443762781186, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71985068, Length=565, Percent_Identity=22.1238938053097, Blast_Score=112, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320548, Length=511, Percent_Identity=27.0058708414873, Blast_Score=177, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6321883, Length=585, Percent_Identity=26.3247863247863, Blast_Score=177, Evalue=4e-45,
Organism=Drosophila melanogaster, GI18859963, Length=617, Percent_Identity=22.2042139384117, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28571570, Length=511, Percent_Identity=23.4833659491194, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_BDEBA (Q6MLI2)

Other databases:

- EMBL:   BX842651
- RefSeq:   NP_968882.1
- ProteinModelPortal:   Q6MLI2
- SMR:   Q6MLI2
- GeneID:   2734744
- GenomeReviews:   BX842601_GR
- KEGG:   bba:Bd2027
- NMPDR:   fig|264462.1.peg.1853
- OMA:   EHTSINP
- PhylomeDB:   Q6MLI2
- BioCyc:   BBAC264462:BD2027-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 65365; Mature: 65365

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKHDSIRLLATNLLKDAIGRAYPDFSASEDDIYKALVNPPKSDLGDLAFGCFILAKALK
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TAPPQVATAVAAQMKGATAVAAGPYINIRFDEQTHGEQVLATILDGSYFKKPLMEKSPKT
CCCHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCC
MIEYSQPNTHKELHVGHMRNLCLGDAIVRMLRYSGREIVSSTFPGDMGTHVAKCLWYMKK
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHH
HNQEPVPETEKGEWLGRMYSKANLLLEDQNGTPQEDINRQELTAILHQLEGKTGPYYDLW
CCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCHHHCCHHHHHHHHHHHCCCCCCEEEEE
LETREWSIELMKKVYAWADVTFDEWYFESEMDSPSAAWVKQLYAEGKLEMSQGAIGKDLE
EECCHHHHHHHHHHHHHHCCCHHHHEECCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCC
SEKLGFCMLLKSDGTGLYATKDLLLAKHKFEDVKIEKSVYVVDMRQALHFKQVFRVLEIL
CCCCCEEEEEECCCCCEEEHHHHHHHHHCCCCEEEECCEEEEEHHHHHHHHHHHHHHHHH
GFEQAKNCFHLQYNYVELPDGAMSSRKGNIVPLRELVHRMEDHVKTTYLSRYKGEWSEED
CHHHHCCEEEEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VEKIAGQVAKGAIFYGMLRMDTNKKIVFDMNEWLKLDGESGPFVQYSYARISSLGRKFPR
HHHHHHHHHHHHHHEEEEEECCCCEEEEECHHHHEECCCCCCEEEEHHHHHHHHHHHCCC
TAGAKIDWSRLNHASERQLMQSLGGFNTAVAAAAENFKPSAICTYLYDLAKSFNVFYHEC
CCCCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEC
PIGTEADVATREARLALSEAVGLTLKNGLAVLGMPAPEKM
CCCCCCCHHHHHHHHHHHHHHCCEECCCEEEEECCCCCCC
>Mature Secondary Structure
MIKHDSIRLLATNLLKDAIGRAYPDFSASEDDIYKALVNPPKSDLGDLAFGCFILAKALK
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TAPPQVATAVAAQMKGATAVAAGPYINIRFDEQTHGEQVLATILDGSYFKKPLMEKSPKT
CCCHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCC
MIEYSQPNTHKELHVGHMRNLCLGDAIVRMLRYSGREIVSSTFPGDMGTHVAKCLWYMKK
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHH
HNQEPVPETEKGEWLGRMYSKANLLLEDQNGTPQEDINRQELTAILHQLEGKTGPYYDLW
CCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCHHHCCHHHHHHHHHHHCCCCCCEEEEE
LETREWSIELMKKVYAWADVTFDEWYFESEMDSPSAAWVKQLYAEGKLEMSQGAIGKDLE
EECCHHHHHHHHHHHHHHCCCHHHHEECCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCC
SEKLGFCMLLKSDGTGLYATKDLLLAKHKFEDVKIEKSVYVVDMRQALHFKQVFRVLEIL
CCCCCEEEEEECCCCCEEEHHHHHHHHHCCCCEEEECCEEEEEHHHHHHHHHHHHHHHHH
GFEQAKNCFHLQYNYVELPDGAMSSRKGNIVPLRELVHRMEDHVKTTYLSRYKGEWSEED
CHHHHCCEEEEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VEKIAGQVAKGAIFYGMLRMDTNKKIVFDMNEWLKLDGESGPFVQYSYARISSLGRKFPR
HHHHHHHHHHHHHHEEEEEECCCCEEEEECHHHHEECCCCCCEEEEHHHHHHHHHHHCCC
TAGAKIDWSRLNHASERQLMQSLGGFNTAVAAAAENFKPSAICTYLYDLAKSFNVFYHEC
CCCCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEC
PIGTEADVATREARLALSEAVGLTLKNGLAVLGMPAPEKM
CCCCCCCHHHHHHHHHHHHHHCCEECCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA