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The map label for this gene is idsA [H]

Identifier: 42523219

GI number: 42523219

Start: 1658687

End: 1659676

Strand: Direct

Name: idsA [H]

Synonym: Bd1723

Alternate gene names: 42523219

Gene position: 1658687-1659676 (Clockwise)

Preceding gene: 42523218

Following gene: 42523220

Centisome position: 43.85

GC content: 52.02

Gene sequence:

>990_bases
GTGAATTTGATTCTTTCTTCAGCTCTTCAAGTGAGCTCTGCATCGAGTGTTGAGCAGTTTTGGAGCACATTTTTGCACGA
TCCTGCCCGGGAATTCATGTCTCGTCCCAAAAAAGAGTTTCGGGCCGAGCTGGTTTCACTGGGTTGCAGGCTTTATTCAA
AGGGAGCTCCGCTTACTGAAAAACAAAAGTCCGTCATCGCCGAGCTGTCCAGGGTCCTTGAATGGATCCATGCCGGTTCA
TTGATCGTTGATGACATTCAGGATGACAGTCTGGAGCGCCGAGGCGGGCCCACCGCCCATCGTTTGTACGGAGTGGGGCC
GGCCCTGAATTTGGGTAACTGGATGTATTTCGAGGCCCTGAAGGGATTGCACGCTCTTCCGGTGGATGATTCTGTCAAAT
TGAAAATCATCAGCTGTGCCCACGAGGCCATGCATCAGGCCCACCTGGGCCAGGCGCTGGATCTGGGGGCGAACATGAAA
ACTCTGTCAGCTGAGCAGATTCAGGAAGTAGTTCATAAAAGTCATTCATTGAAAAGCGGCGCTTTGGTGGCGCTGGCCAT
GCAGGTGGGCGCCCTGATCGGAGATGCGCAGGCGGACCTTCAGCTTTTGCAGGAGCTGGGAATGCAGCTGGGATCGTCTC
TGCAGCGCTTTGATGATCTTGGAAATTTAAAATTTAACTGTACTGACAGCAAGGCGCTGGAAGATCTGAAGCTGGGCCGT
CCTTCCTGGATTTGGATGTTTTTGGCCTCGTGCGGGGACAGCGCTGAAATCCGGGCCTTCAAAGACTGCCTGGAGTTCTT
GCCCGAGACTCACGCGTTGGAAAGTTTCGTGCAAAGTGCGGATTTGAAAAAACGCGCCCACGCAGAAGCCCTCAGGCTTC
ATCGTGAAATGGAAGAAAGACTGAAAGCGTCTTTTGCCGGTCTTGAGAACGCCCAGACACTAAACCTACTAAAAAACCTG
ACAGAGAGAATTGTCCATGCCTATGAATAA

Upstream 100 bases:

>100_bases
ATGCCCCAACAAAGGGTGCTTTATATTTTAATGACATCATCACGGAGTTACTTTAGTTACTCACTTTGGCCCCGGGGTAA
TAATTTGAGGAGTTATTCTA

Downstream 100 bases:

>100_bases
AAAAGTTGCAGTAATTGGAAGTGGATTCGGTGGATTGAGTGCCGCCATTCGTCTTCAGGCCGCGGGCTTTGAAGTTCGTA
TTTTTGAAAAGCGGGATATG

Product: putative octaprenyl-diphosphate synthase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNLILSSALQVSSASSVEQFWSTFLHDPAREFMSRPKKEFRAELVSLGCRLYSKGAPLTEKQKSVIAELSRVLEWIHAGS
LIVDDIQDDSLERRGGPTAHRLYGVGPALNLGNWMYFEALKGLHALPVDDSVKLKIISCAHEAMHQAHLGQALDLGANMK
TLSAEQIQEVVHKSHSLKSGALVALAMQVGALIGDAQADLQLLQELGMQLGSSLQRFDDLGNLKFNCTDSKALEDLKLGR
PSWIWMFLASCGDSAEIRAFKDCLEFLPETHALESFVQSADLKKRAHAEALRLHREMEERLKASFAGLENAQTLNLLKNL
TERIVHAYE

Sequences:

>Translated_329_residues
MNLILSSALQVSSASSVEQFWSTFLHDPAREFMSRPKKEFRAELVSLGCRLYSKGAPLTEKQKSVIAELSRVLEWIHAGS
LIVDDIQDDSLERRGGPTAHRLYGVGPALNLGNWMYFEALKGLHALPVDDSVKLKIISCAHEAMHQAHLGQALDLGANMK
TLSAEQIQEVVHKSHSLKSGALVALAMQVGALIGDAQADLQLLQELGMQLGSSLQRFDDLGNLKFNCTDSKALEDLKLGR
PSWIWMFLASCGDSAEIRAFKDCLEFLPETHALESFVQSADLKKRAHAEALRLHREMEERLKASFAGLENAQTLNLLKNL
TERIVHAYE
>Mature_329_residues
MNLILSSALQVSSASSVEQFWSTFLHDPAREFMSRPKKEFRAELVSLGCRLYSKGAPLTEKQKSVIAELSRVLEWIHAGS
LIVDDIQDDSLERRGGPTAHRLYGVGPALNLGNWMYFEALKGLHALPVDDSVKLKIISCAHEAMHQAHLGQALDLGANMK
TLSAEQIQEVVHKSHSLKSGALVALAMQVGALIGDAQADLQLLQELGMQLGSSLQRFDDLGNLKFNCTDSKALEDLKLGR
PSWIWMFLASCGDSAEIRAFKDCLEFLPETHALESFVQSADLKKRAHAEALRLHREMEERLKASFAGLENAQTLNLLKNL
TERIVHAYE

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI4758430, Length=231, Percent_Identity=30.7359307359307, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI83700220, Length=231, Percent_Identity=30.7359307359307, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1789578, Length=236, Percent_Identity=25.8474576271186, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6325188, Length=229, Percent_Identity=27.0742358078603, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281365769, Length=240, Percent_Identity=27.9166666666667, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24660002, Length=240, Percent_Identity=27.9166666666667, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 36470; Mature: 36470

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLILSSALQVSSASSVEQFWSTFLHDPAREFMSRPKKEFRAELVSLGCRLYSKGAPLTE
CCCHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCH
KQKSVIAELSRVLEWIHAGSLIVDDIQDDSLERRGGPTAHRLYGVGPALNLGNWMYFEAL
HHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHCCCCCHHHHCCCCCCCCCCCHHHHHHH
KGLHALPVDDSVKLKIISCAHEAMHQAHLGQALDLGANMKTLSAEQIQEVVHKSHSLKSG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHCCCCH
ALVALAMQVGALIGDAQADLQLLQELGMQLGSSLQRFDDLGNLKFNCTDSKALEDLKLGR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHCCC
PSWIWMFLASCGDSAEIRAFKDCLEFLPETHALESFVQSADLKKRAHAEALRLHREMEER
CHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKASFAGLENAQTLNLLKNLTERIVHAYE
HHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLILSSALQVSSASSVEQFWSTFLHDPAREFMSRPKKEFRAELVSLGCRLYSKGAPLTE
CCCHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCH
KQKSVIAELSRVLEWIHAGSLIVDDIQDDSLERRGGPTAHRLYGVGPALNLGNWMYFEAL
HHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHCCCCCHHHHCCCCCCCCCCCHHHHHHH
KGLHALPVDDSVKLKIISCAHEAMHQAHLGQALDLGANMKTLSAEQIQEVVHKSHSLKSG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHCCCCH
ALVALAMQVGALIGDAQADLQLLQELGMQLGSSLQRFDDLGNLKFNCTDSKALEDLKLGR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHCCC
PSWIWMFLASCGDSAEIRAFKDCLEFLPETHALESFVQSADLKKRAHAEALRLHREMEER
CHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKASFAGLENAQTLNLLKNLTERIVHAYE
HHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]