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The map label for this gene is hchA [H]

Identifier: 42523028

GI number: 42523028

Start: 1444592

End: 1445347

Strand: Direct

Name: hchA [H]

Synonym: Bd1521

Alternate gene names: 42523028

Gene position: 1444592-1445347 (Clockwise)

Preceding gene: 42523027

Following gene: 42523029

Centisome position: 38.19

GC content: 53.04

Gene sequence:

>756_bases
ATGAAAAGCAACAAAGTGCTTTTTGTTCTGACTAGTACCGAGCAGCTTGGCGATACCGGCCATCATACAGGCGCTTATCT
TTCTGAAATCACCCATCCTTATGATGAATTTGTGCGTGCGGGATACGAAGTGGACATGATCAGCCCTCTGGGCGGCAAAG
TGCCCCTGGATGGTGTGAAAATGGATGATCCCATCAATGCCACGTGGATGAATGACGAAGAGTTTCTGTCCAAGGTGGAA
GGCACCGTGAAACCCTGGCAGGTTTCAAGTCGCGATTATTGCGCGATCTATTTTGCCGGCGGGCATGGGACGATGTTTGA
TTTTCCCGAAAATCTGCAGCTGCAAAAGCTGACAGCGGAAATCTATGAAAACAACGGTGTGGTCGGGGCGGTCTGCCATG
GCCCGGCAGCGCTGGTGAATGTCCGGCTTTCTGATGGACAGTATCTGATCAAAGGTCACGAAGTTTCCAGCTTCACCAAC
GAAGAGGAAGAGTTTGTCGGTATGGAAAAGTCCGTTCCGTTTTTACTGCAAACGCGTCTGCAGGAGCGCGGTGCCCACCA
TACGTCGTCTCCGAAATTTGCCGGACATGTGGTTAAAAGTGGCCGCCTGGTGACCGGGCAAAATCCCGCCTCGGCGGCCG
GTGTCGGCAAAGCCATGGTGGAGGTTCTGGATTTTATCGAAGAAGGCCGCATCGTGCCCGAGCAGAACTGGTGTGAATGG
CATGAACCCCCACAGCACCATCGAGGTGGTCTGTGA

Upstream 100 bases:

>100_bases
TTTTTCGGGGAATGATTGTTGATTTGCACTTGTGCTGGCATAGCTTTGAGTTCGCAAGCCCGCTTTGAGAAGATAGTGGT
ATTGCGAAGGAGGAACGGCC

Downstream 100 bases:

>100_bases
CGGATGACTCACGCATCATCGCCAAGAGCCCGCGCTTTTTGGAGGTGCTGGATCTGGCTCGGCGGGTGGCGGCCAGTTCG
GCCAATGTTCTGATCACAGG

Product: intracellular protease/amidase, putative

Products: NA

Alternate protein names: Hsp31 [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKSNKVLFVLTSTEQLGDTGHHTGAYLSEITHPYDEFVRAGYEVDMISPLGGKVPLDGVKMDDPINATWMNDEEFLSKVE
GTVKPWQVSSRDYCAIYFAGGHGTMFDFPENLQLQKLTAEIYENNGVVGAVCHGPAALVNVRLSDGQYLIKGHEVSSFTN
EEEEFVGMEKSVPFLLQTRLQERGAHHTSSPKFAGHVVKSGRLVTGQNPASAAGVGKAMVEVLDFIEEGRIVPEQNWCEW
HEPPQHHRGGL

Sequences:

>Translated_251_residues
MKSNKVLFVLTSTEQLGDTGHHTGAYLSEITHPYDEFVRAGYEVDMISPLGGKVPLDGVKMDDPINATWMNDEEFLSKVE
GTVKPWQVSSRDYCAIYFAGGHGTMFDFPENLQLQKLTAEIYENNGVVGAVCHGPAALVNVRLSDGQYLIKGHEVSSFTN
EEEEFVGMEKSVPFLLQTRLQERGAHHTSSPKFAGHVVKSGRLVTGQNPASAAGVGKAMVEVLDFIEEGRIVPEQNWCEW
HEPPQHHRGGL
>Mature_251_residues
MKSNKVLFVLTSTEQLGDTGHHTGAYLSEITHPYDEFVRAGYEVDMISPLGGKVPLDGVKMDDPINATWMNDEEFLSKVE
GTVKPWQVSSRDYCAIYFAGGHGTMFDFPENLQLQKLTAEIYENNGVVGAVCHGPAALVNVRLSDGQYLIKGHEVSSFTN
EEEEFVGMEKSVPFLLQTRLQERGAHHTSSPKFAGHVVKSGRLVTGQNPASAAGVGKAMVEVLDFIEEGRIVPEQNWCEW
HEPPQHHRGGL

Specific function: Uses temperature-induced exposure of structured hydrophobic domains to capture and stabilize early unfolding protein intermediates under severe thermal stress. It rapidly releases them once stress has abated [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family. HchA subfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320742, Length=241, Percent_Identity=32.3651452282158, Blast_Score=112, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6324967, Length=232, Percent_Identity=28.8793103448276, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323984, Length=232, Percent_Identity=28.8793103448276, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324975, Length=232, Percent_Identity=28.8793103448276, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017283
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 27710; Mature: 27710

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNKVLFVLTSTEQLGDTGHHTGAYLSEITHPYDEFVRAGYEVDMISPLGGKVPLDGVK
CCCCCEEEEEECCHHHCCCCCCCHHHHHHHCCCHHHHHHCCCCEEEECCCCCCCCCCCCC
MDDPINATWMNDEEFLSKVEGTVKPWQVSSRDYCAIYFAGGHGTMFDFPENLQLQKLTAE
CCCCCCEEECCHHHHHHHHCCCCCCEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHH
IYENNGVVGAVCHGPAALVNVRLSDGQYLIKGHEVSSFTNEEEEFVGMEKSVPFLLQTRL
HHHCCCCEEEEECCCEEEEEEEECCCEEEEECCCCCCCCCCHHHHHCCCCCCCHHHHHHH
QERGAHHTSSPKFAGHVVKSGRLVTGQNPASAAGVGKAMVEVLDFIEEGRIVPEQNWCEW
HHCCCCCCCCCCHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
HEPPQHHRGGL
CCCHHHCCCCC
>Mature Secondary Structure
MKSNKVLFVLTSTEQLGDTGHHTGAYLSEITHPYDEFVRAGYEVDMISPLGGKVPLDGVK
CCCCCEEEEEECCHHHCCCCCCCHHHHHHHCCCHHHHHHCCCCEEEECCCCCCCCCCCCC
MDDPINATWMNDEEFLSKVEGTVKPWQVSSRDYCAIYFAGGHGTMFDFPENLQLQKLTAE
CCCCCCEEECCHHHHHHHHCCCCCCEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHH
IYENNGVVGAVCHGPAALVNVRLSDGQYLIKGHEVSSFTNEEEEFVGMEKSVPFLLQTRL
HHHCCCCEEEEECCCEEEEEEEECCCEEEEECCCCCCCCCCHHHHHCCCCCCCHHHHHHH
QERGAHHTSSPKFAGHVVKSGRLVTGQNPASAAGVGKAMVEVLDFIEEGRIVPEQNWCEW
HHCCCCCCCCCCHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
HEPPQHHRGGL
CCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA