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The map label for this gene is lolC [H]

Identifier: 42522999

GI number: 42522999

Start: 1410402

End: 1411619

Strand: Direct

Name: lolC [H]

Synonym: Bd1490

Alternate gene names: 42522999

Gene position: 1410402-1411619 (Clockwise)

Preceding gene: 42522998

Following gene: 42523000

Centisome position: 37.28

GC content: 52.05

Gene sequence:

>1218_bases
TTGCCTTGGCTTTCCTGGCGACTGCTTTTCTCGCGCAAAACCATGTTTGGCGGCTCGGCTCCTTTGGCCTTGCTCGGACT
GGTTTTGGGGGTGGCAGCGCTGGTGGCCTCGATGGCGGTGATGAGTGGTTTTGAAAACACTCTAAAAACAGCCATGGCCG
AAGTGTCTGGCCACGCACAAGTGGTGAAGCGCTCGCGCTTTCCGGATGACTGGAAAGAACTGGAAGAGCGCATTCGCAAA
GCCGAACCCACGCTGGTTAACACCAGCCGTTTTGTCTTTATTGAGGCGGTTTTGGCCAACAAAGGTCAGATCTCAGGTGT
TCTGATTCAAGGTGTGGACACTCAGCGGGTCAATGAGGTTTTGAACTTCAAACGCCGTGTTCTGAGCGGAACAGATGATC
TGAATGTGGCCAGTGATGTGCCTTTGGCGCTGGTGGGTAAAAATCTGGCAAAAAAAATGAATCTGAATGTCGGAGACACC
TTCCGTGTGGTGGTTCCGGTCGCGGACTCTGTGGATCCGTCAAAGTTCCAGCGCCGGGTGGGGGCTTTTAAAGTCCAGGG
CATTTTGGACCTGGGAAAGCACGACTGGAATGAGCGGTTTATTCTGTCTGATTTGAAGGCCACCCAGGATCTGGCGGATA
TCGGAGATCGTTATTCGGGCTTGTTGTTGAAGTTCCAGGATGTGGATCATGCCCGTGACGCCGCTTTCAATTTGAGTGCG
GTTTTGGGATCCCCTTATTGGGTGCGCGACTGGCGCGATGCCAATGAAAACCTTTTTGAAGCCATCAATGTCGAGCGGCC
GGGAATCTTTTTCGTGGTTTTGGTGATCACCATTGTGGCGGCCTTCAATGTGTCGGCGACTTTATTTGTGAACGTGGTTC
GTCGTTTCAAGGACATTGCCATTCTAAAGACCGTGGGTCTGTCGCAAAAAGACATTATGAAAATCTTTGTCTGCCAGGGC
TTGTTTATGGGCCTGGTGGGGATCGTTCTGGGGTTTGCTCTGGGGGTCGGGATTGCCTATCTGTTTGAATTCATGCAGGG
GCGTTTAAGTCTGATTTCCGGCGAGGTGTATCGTTTGGAAAATATTGAATTGCAAATTCGTTTCGTCGATGGCGTGGCCA
TCTGTGTTGCGACACTTGTGATCTGTTTGATTGCCACGATCGCACCGGCACGTCGCGGAGCGAAGCTGGAGCCGGTGGAG
GGACTGAGAAGTGAATAG

Upstream 100 bases:

>100_bases
ATCAGGTCGATGACGTGATGGACGGGGATCTGGATGGATTTATCATGTCTTACTTGAAATCGACTTTGACGGCAGAAAGT
CAGCCTTCGTGAAGTCTTCA

Downstream 100 bases:

>100_bases
CGAAAACATTCTTTTGCGTGCGGTGGATATTCACAAATCCTATTCCCAAGGGGTGGGTGAGCTGGAGATTCTTCGTGGAG
TCAGTCTGGACATCCGTGAA

Product: lipoprotein releasing system transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MPWLSWRLLFSRKTMFGGSAPLALLGLVLGVAALVASMAVMSGFENTLKTAMAEVSGHAQVVKRSRFPDDWKELEERIRK
AEPTLVNTSRFVFIEAVLANKGQISGVLIQGVDTQRVNEVLNFKRRVLSGTDDLNVASDVPLALVGKNLAKKMNLNVGDT
FRVVVPVADSVDPSKFQRRVGAFKVQGILDLGKHDWNERFILSDLKATQDLADIGDRYSGLLLKFQDVDHARDAAFNLSA
VLGSPYWVRDWRDANENLFEAINVERPGIFFVVLVITIVAAFNVSATLFVNVVRRFKDIAILKTVGLSQKDIMKIFVCQG
LFMGLVGIVLGFALGVGIAYLFEFMQGRLSLISGEVYRLENIELQIRFVDGVAICVATLVICLIATIAPARRGAKLEPVE
GLRSE

Sequences:

>Translated_405_residues
MPWLSWRLLFSRKTMFGGSAPLALLGLVLGVAALVASMAVMSGFENTLKTAMAEVSGHAQVVKRSRFPDDWKELEERIRK
AEPTLVNTSRFVFIEAVLANKGQISGVLIQGVDTQRVNEVLNFKRRVLSGTDDLNVASDVPLALVGKNLAKKMNLNVGDT
FRVVVPVADSVDPSKFQRRVGAFKVQGILDLGKHDWNERFILSDLKATQDLADIGDRYSGLLLKFQDVDHARDAAFNLSA
VLGSPYWVRDWRDANENLFEAINVERPGIFFVVLVITIVAAFNVSATLFVNVVRRFKDIAILKTVGLSQKDIMKIFVCQG
LFMGLVGIVLGFALGVGIAYLFEFMQGRLSLISGEVYRLENIELQIRFVDGVAICVATLVICLIATIAPARRGAKLEPVE
GLRSE
>Mature_404_residues
PWLSWRLLFSRKTMFGGSAPLALLGLVLGVAALVASMAVMSGFENTLKTAMAEVSGHAQVVKRSRFPDDWKELEERIRKA
EPTLVNTSRFVFIEAVLANKGQISGVLIQGVDTQRVNEVLNFKRRVLSGTDDLNVASDVPLALVGKNLAKKMNLNVGDTF
RVVVPVADSVDPSKFQRRVGAFKVQGILDLGKHDWNERFILSDLKATQDLADIGDRYSGLLLKFQDVDHARDAAFNLSAV
LGSPYWVRDWRDANENLFEAINVERPGIFFVVLVITIVAAFNVSATLFVNVVRRFKDIAILKTVGLSQKDIMKIFVCQGL
FMGLVGIVLGFALGVGIAYLFEFMQGRLSLISGEVYRLENIELQIRFVDGVAICVATLVICLIATIAPARRGAKLEPVEG
LRSE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=391, Percent_Identity=24.0409207161125, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787360, Length=401, Percent_Identity=25.1870324189526, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44644; Mature: 44513

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWLSWRLLFSRKTMFGGSAPLALLGLVLGVAALVASMAVMSGFENTLKTAMAEVSGHAQ
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VVKRSRFPDDWKELEERIRKAEPTLVNTSRFVFIEAVLANKGQISGVLIQGVDTQRVNEV
HHHHCCCCHHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCCCCCEEEEECCCHHHHHHH
LNFKRRVLSGTDDLNVASDVPLALVGKNLAKKMNLNVGDTFRVVVPVADSVDPSKFQRRV
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHH
GAFKVQGILDLGKHDWNERFILSDLKATQDLADIGDRYSGLLLKFQDVDHARDAAFNLSA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHCCEEEEEECCCCHHHHHHHHHH
VLGSPYWVRDWRDANENLFEAINVERPGIFFVVLVITIVAAFNVSATLFVNVVRRFKDIA
HHCCCCEEECHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ILKTVGLSQKDIMKIFVCQGLFMGLVGIVLGFALGVGIAYLFEFMQGRLSLISGEVYRLE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
NIELQIRFVDGVAICVATLVICLIATIAPARRGAKLEPVEGLRSE
CEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PWLSWRLLFSRKTMFGGSAPLALLGLVLGVAALVASMAVMSGFENTLKTAMAEVSGHAQ
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VVKRSRFPDDWKELEERIRKAEPTLVNTSRFVFIEAVLANKGQISGVLIQGVDTQRVNEV
HHHHCCCCHHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCCCCCEEEEECCCHHHHHHH
LNFKRRVLSGTDDLNVASDVPLALVGKNLAKKMNLNVGDTFRVVVPVADSVDPSKFQRRV
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHH
GAFKVQGILDLGKHDWNERFILSDLKATQDLADIGDRYSGLLLKFQDVDHARDAAFNLSA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHCCEEEEEECCCCHHHHHHHHHH
VLGSPYWVRDWRDANENLFEAINVERPGIFFVVLVITIVAAFNVSATLFVNVVRRFKDIA
HHCCCCEEECHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ILKTVGLSQKDIMKIFVCQGLFMGLVGIVLGFALGVGIAYLFEFMQGRLSLISGEVYRLE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
NIELQIRFVDGVAICVATLVICLIATIAPARRGAKLEPVEGLRSE
CEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]