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The map label for this gene is tcp [H]

Identifier: 42522860

GI number: 42522860

Start: 1267526

End: 1269121

Strand: Direct

Name: tcp [H]

Synonym: Bd1340

Alternate gene names: 42522860

Gene position: 1267526-1269121 (Clockwise)

Preceding gene: 42522859

Following gene: 42522861

Centisome position: 33.51

GC content: 53.51

Gene sequence:

>1596_bases
ATGAACGTACGCAGTTTAAACTTTAAAGTGTCTGTGATTGTTGGGATCCTAGTTGTTTGTTCGGCATTGATTGCGGTCAT
GAGCTGGCGAAGTCTTGGCGAGTTGAATTCGACTTTGACTCGCATCACGAATGTCACTGTGCCTCGAATTGATCGGGATC
ACATGATGAAAGAGATCTTCCTTACCCAGGTTATCAATGAAAGAAACTTTGCACTGAATCCTGCGGGGGGACCGGCGCGG
GAGGCGGCTCGTAAGTACATTTCGGAACGCCACAAAGAGATGGCGGAAGTGCTGGAAGAGCGCAAAGCCCTGGCGGATGA
AGCGGGGGTGAAAAGGATCGCGGCCTTCGAAGCCGTTTATAAAGAGTGGACGGATCTTAACACTCAGGTGACCGAGCTCT
TTGACAAAGGTCAGGACAAAGAAGCACTGAATATTCTTGTCACCAAGGGGCGCGATGTCCGTGTGCGGGGGACGGAAATC
GTGGATACCATGGTCAAGAGCAATAACGAGCGCATGCAGGCTGATCAGAAGTCTGCCGAGGCCTCTTTTGCGCGTTCGCG
TGACCTGTTGCTGGGCACAGTCGTGGGGGCTCTGCTTTTCGGTATCGCTTGTGCTTTCCTGGTTCTTAGGTCTCTTAGTG
CGGGTATCAACCGTGTTATTTCAGAGCTGACTGACAATTCCACTCAGGTGTCGGGGGCTTCCCAGCAGATCTCGGTTTCT
TCCGAACAGCTGGCGGAGGCTTCTTCTGAACAGGCGGCTTCTTTGGAAGAGACCGTGGCAACACTGGAGGAACTGACTTC
CATGATCAAGATCAATGCCGATAATGCCCGTGAGGCGGCCCGTCTTTCCGGAGAGACCAGTCAGGTGGCCAGCCGCGGTG
ATCAAGAGATTCATTCTTTGATGGATTCCATGCAGGCGATTTCCCAGGACTCCAAGCGCATTGAAGAAATTATTAATGTG
ATTGACGACATTGCCTTCCAGACGAACTTGCTGGCGCTGAATGCGGCGGTGGAAGCCGCGCGTGCGGGCGAGCAAGGAAA
AGGTTTTGCGGTTGTGGCGGAGGCGGTTCGTAATCTGGCTCAGCGCAGTTCATCAGCAGCAAAGGATATCACGGAGCTTA
TCAAAGGCAGCGTTGAGAAAATTGACCGAGGTGCCCATCAGGCTCAGCAAAGTGGGAGAGTGCTGGGTGAAATTGTGCAA
TCAGCCCAGAAGGTGTCCAGTCTGAATGCTGAAATTGCCAGCGCCAGTGAAGAGCAATCCAACGGCGTCAATCAAATCAG
CAAAGCCATGAATCAATTGGATCAAGTGACACAAGTCAACGCCGCGACCTCGGAAGAAGCCGCCGCCGCTTCGCAAGAGC
TGTCCGCCCAGGCCCAGCAGTTGGATAAAGTCGTGGATCTTTTGACCTACACCATCAAGGGCGTGCGCCGGGAAATCGCA
GCCGCCGCCAGCGGTGCGCAGTCAAAAGCCAAAACCATTGACATCAAGTCAGCCCGAAGGCACCCGGCCCCAAAGGTGGC
CCCCCACAAAGTTTCGTCAGTAAAAAGTGACTCCATGGATGACTGGGGCAAAGTAGGAACCACCGACGGCTTCTAA

Upstream 100 bases:

>100_bases
CAAGATTATTTCACACCTTTAGTGCTTAGGTTTCTTTGGGGTCGACCCGATAAATTTGGCCATCGCTGGGGAATGCGATG
GCTTTTGTCGGGGGAGAATA

Downstream 100 bases:

>100_bases
AAGGTGCCTTAAAAGGTGCCTGGTGACTTTTTACATCTACGCCGCAGCATGAACGGTGTAGGCATTGTTATCTGTCTTCA
CCGTGATAGGGTTCTAAGAT

Product: putative methyl accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MNVRSLNFKVSVIVGILVVCSALIAVMSWRSLGELNSTLTRITNVTVPRIDRDHMMKEIFLTQVINERNFALNPAGGPAR
EAARKYISERHKEMAEVLEERKALADEAGVKRIAAFEAVYKEWTDLNTQVTELFDKGQDKEALNILVTKGRDVRVRGTEI
VDTMVKSNNERMQADQKSAEASFARSRDLLLGTVVGALLFGIACAFLVLRSLSAGINRVISELTDNSTQVSGASQQISVS
SEQLAEASSEQAASLEETVATLEELTSMIKINADNAREAARLSGETSQVASRGDQEIHSLMDSMQAISQDSKRIEEIINV
IDDIAFQTNLLALNAAVEAARAGEQGKGFAVVAEAVRNLAQRSSSAAKDITELIKGSVEKIDRGAHQAQQSGRVLGEIVQ
SAQKVSSLNAEIASASEEQSNGVNQISKAMNQLDQVTQVNAATSEEAAAASQELSAQAQQLDKVVDLLTYTIKGVRREIA
AAASGAQSKAKTIDIKSARRHPAPKVAPHKVSSVKSDSMDDWGKVGTTDGF

Sequences:

>Translated_531_residues
MNVRSLNFKVSVIVGILVVCSALIAVMSWRSLGELNSTLTRITNVTVPRIDRDHMMKEIFLTQVINERNFALNPAGGPAR
EAARKYISERHKEMAEVLEERKALADEAGVKRIAAFEAVYKEWTDLNTQVTELFDKGQDKEALNILVTKGRDVRVRGTEI
VDTMVKSNNERMQADQKSAEASFARSRDLLLGTVVGALLFGIACAFLVLRSLSAGINRVISELTDNSTQVSGASQQISVS
SEQLAEASSEQAASLEETVATLEELTSMIKINADNAREAARLSGETSQVASRGDQEIHSLMDSMQAISQDSKRIEEIINV
IDDIAFQTNLLALNAAVEAARAGEQGKGFAVVAEAVRNLAQRSSSAAKDITELIKGSVEKIDRGAHQAQQSGRVLGEIVQ
SAQKVSSLNAEIASASEEQSNGVNQISKAMNQLDQVTQVNAATSEEAAAASQELSAQAQQLDKVVDLLTYTIKGVRREIA
AAASGAQSKAKTIDIKSARRHPAPKVAPHKVSSVKSDSMDDWGKVGTTDGF
>Mature_531_residues
MNVRSLNFKVSVIVGILVVCSALIAVMSWRSLGELNSTLTRITNVTVPRIDRDHMMKEIFLTQVINERNFALNPAGGPAR
EAARKYISERHKEMAEVLEERKALADEAGVKRIAAFEAVYKEWTDLNTQVTELFDKGQDKEALNILVTKGRDVRVRGTEI
VDTMVKSNNERMQADQKSAEASFARSRDLLLGTVVGALLFGIACAFLVLRSLSAGINRVISELTDNSTQVSGASQQISVS
SEQLAEASSEQAASLEETVATLEELTSMIKINADNAREAARLSGETSQVASRGDQEIHSLMDSMQAISQDSKRIEEIINV
IDDIAFQTNLLALNAAVEAARAGEQGKGFAVVAEAVRNLAQRSSSAAKDITELIKGSVEKIDRGAHQAQQSGRVLGEIVQ
SAQKVSSLNAEIASASEEQSNGVNQISKAMNQLDQVTQVNAATSEEAAAASQELSAQAQQLDKVVDLLTYTIKGVRREIA
AAASGAQSKAKTIDIKSARRHPAPKVAPHKVSSVKSDSMDDWGKVGTTDGF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=260, Percent_Identity=45, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1788194, Length=268, Percent_Identity=43.2835820895522, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI2367378, Length=232, Percent_Identity=46.1206896551724, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI1788195, Length=223, Percent_Identity=45.7399103139013, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1789453, Length=269, Percent_Identity=37.546468401487, Blast_Score=172, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57192; Mature: 57192

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVRSLNFKVSVIVGILVVCSALIAVMSWRSLGELNSTLTRITNVTVPRIDRDHMMKEIF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LTQVINERNFALNPAGGPAREAARKYISERHKEMAEVLEERKALADEAGVKRIAAFEAVY
HHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEWTDLNTQVTELFDKGQDKEALNILVTKGRDVRVRGTEIVDTMVKSNNERMQADQKSAE
HHHHCCCHHHHHHHHCCCCHHHHHHHEECCCCEEECHHHHHHHHHHCCCHHHHHHHHHHH
ASFARSRDLLLGTVVGALLFGIACAFLVLRSLSAGINRVISELTDNSTQVSGASQQISVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCC
SEQLAEASSEQAASLEETVATLEELTSMIKINADNAREAARLSGETSQVASRGDQEIHSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHCCHHHHHHH
MDSMQAISQDSKRIEEIINVIDDIAFQTNLLALNAAVEAARAGEQGKGFAVVAEAVRNLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
QRSSSAAKDITELIKGSVEKIDRGAHQAQQSGRVLGEIVQSAQKVSSLNAEIASASEEQS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
NGVNQISKAMNQLDQVTQVNAATSEEAAAASQELSAQAQQLDKVVDLLTYTIKGVRREIA
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAASGAQSKAKTIDIKSARRHPAPKVAPHKVSSVKSDSMDDWGKVGTTDGF
HHHCCCHHHHHEEEHHHHCCCCCCCCCCHHHHHCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure
MNVRSLNFKVSVIVGILVVCSALIAVMSWRSLGELNSTLTRITNVTVPRIDRDHMMKEIF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LTQVINERNFALNPAGGPAREAARKYISERHKEMAEVLEERKALADEAGVKRIAAFEAVY
HHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEWTDLNTQVTELFDKGQDKEALNILVTKGRDVRVRGTEIVDTMVKSNNERMQADQKSAE
HHHHCCCHHHHHHHHCCCCHHHHHHHEECCCCEEECHHHHHHHHHHCCCHHHHHHHHHHH
ASFARSRDLLLGTVVGALLFGIACAFLVLRSLSAGINRVISELTDNSTQVSGASQQISVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCC
SEQLAEASSEQAASLEETVATLEELTSMIKINADNAREAARLSGETSQVASRGDQEIHSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHCCHHHHHHH
MDSMQAISQDSKRIEEIINVIDDIAFQTNLLALNAAVEAARAGEQGKGFAVVAEAVRNLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
QRSSSAAKDITELIKGSVEKIDRGAHQAQQSGRVLGEIVQSAQKVSSLNAEIASASEEQS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
NGVNQISKAMNQLDQVTQVNAATSEEAAAASQELSAQAQQLDKVVDLLTYTIKGVRREIA
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAASGAQSKAKTIDIKSARRHPAPKVAPHKVSSVKSDSMDDWGKVGTTDGF
HHHCCCHHHHHEEEHHHHCCCCCCCCCCHHHHHCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]