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The map label for this gene is pqqL [C]

Identifier: 42522631

GI number: 42522631

Start: 1020342

End: 1021742

Strand: Direct

Name: pqqL [C]

Synonym: Bd1077

Alternate gene names: 42522631

Gene position: 1020342-1021742 (Clockwise)

Preceding gene: 42522630

Following gene: 42522632

Centisome position: 26.97

GC content: 50.39

Gene sequence:

>1401_bases
ATGAAAAGGATTTCTACTTTGCTCTTGGGGCTGAGCCTGTCCCTGTCTGCTCATGCCGTGGATCCAACACCGGTACCGAA
AACACCAGATAAAGACGTTATCGGCGCCATCCAAGGATGGGCACCCAAAAACGATTTGAAGATTTCCCTGCCGGTGACCA
AGTTCACCCTGGAAAACGGTCTGACCGTGCTTCTTTTAGAGGACCACGCGGTTCCGATGGTCAGTTATCACACCTGGTAC
CGTGTGGGCTCCCGCGATGAATCCCCGGGTGTGACAGGGGCTGCGCACATGCTGGAACATATGATGTTTAAGGGGGCTAA
GAAGTATGACGGCAAATCCTTTGACCGCATCTTCCATGAAAACGGCATCACCAACAATGCTTTCACCACCAATGACTACA
CCGGCTTCTATGAAAACCTGCCCAGCTCCAAACTGGAGCTGGTGATGGATATGGAAGTGGACCGCATGAGTTCGCTTCTG
ATCAGCCCCGAAGACCTGAAGAGCGAAAAAGAAGTCGTGAAAGAAGAACGGCGCTGGAGAGTCGACAACAATCCGATGGG
TCTTTTGCGCGAACTGATGATGGGCACGATCTTTAAAGTGCACCCTTACAAATGGCCGGTGATTGGCCACATGAAGGACA
TCGAGGCTTATGATTCTGAAAAGCTTCGCTACTTCTATAACACCTTCTATGTGCCGAACAATGCGGTGCTGGTGGTGGTC
GGTGACTTCAACACCTCCAAAGTAAAAAGTCTGATTGAAAAGTACTATGGCAAATTGCCTTCCCGTCCTTTGCCGGAAAG
AAAATATCCTTCCGAGCCGGCGCAAAAAGTTCAGCAGAACGCAACGTTGCGCAAAGACGTTCAGAACACTTCTTTCGTAG
TTGCCTATAAGAGCCCGAAACAGGGGCAGCCTGATATGTACGCTCTGGATCTGGCCGCGAACATTCTGGGTTATGGAACG
TCCAGCCGTCTGCACAAGCGTCTGGTGTACCAAAAGCAAACAGCGACTTCCGCTTATTCCTACAACTATGCCATGCAGGA
CGAGGGGATGTTCGCCGTGGGTGTGAACCTGAAACCGGGTCAGGCGCCTCAAGAGGCTCTTGATGTTGTGTATAACGAAA
TCTGGAAGCTGCGTAATCAGAAAGTGACTGAAGCAGAGCTTGAAAAAGCCAAAACCCAGGTGATGAAGGATCTGGTGGAT
TCTTTGAAAACCATGGACGGCAAAGCGCGCGCCCTGGCCGTGAACGAAATCGTCACTGGCAGCTATCAAAGCCTGTTCAC
AGATCTGGAAAAATACCAGGCCGTGACTGCGGATGACATCAAACGTGTTGCTGACAAGTATACACAACAGACTCAACGCT
CGATCATCACCCTTGAACCCAAAGTGAAAAAGGAACAGTAG

Upstream 100 bases:

>100_bases
CAAGATCTGCCAAAAGTCTTAAAAGTCCTGAAGTTCGTTGTAATCATGGCCCCTCAGTTTCAAACTAGGGGTTATTGCAT
AACCAACGAAAGAAGCATCT

Downstream 100 bases:

>100_bases
ACATGAGAAATTTAGCCTTAGCTTTGACTTTGCCTTTGGTGTGCACCGCGGTTGTTTCCTGCTCCAGTTCCGGAAAAAAA
ACCGTCACTAAACCACCTTC

Product: protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKRISTLLLGLSLSLSAHAVDPTPVPKTPDKDVIGAIQGWAPKNDLKISLPVTKFTLENGLTVLLLEDHAVPMVSYHTWY
RVGSRDESPGVTGAAHMLEHMMFKGAKKYDGKSFDRIFHENGITNNAFTTNDYTGFYENLPSSKLELVMDMEVDRMSSLL
ISPEDLKSEKEVVKEERRWRVDNNPMGLLRELMMGTIFKVHPYKWPVIGHMKDIEAYDSEKLRYFYNTFYVPNNAVLVVV
GDFNTSKVKSLIEKYYGKLPSRPLPERKYPSEPAQKVQQNATLRKDVQNTSFVVAYKSPKQGQPDMYALDLAANILGYGT
SSRLHKRLVYQKQTATSAYSYNYAMQDEGMFAVGVNLKPGQAPQEALDVVYNEIWKLRNQKVTEAELEKAKTQVMKDLVD
SLKTMDGKARALAVNEIVTGSYQSLFTDLEKYQAVTADDIKRVADKYTQQTQRSIITLEPKVKKEQ

Sequences:

>Translated_466_residues
MKRISTLLLGLSLSLSAHAVDPTPVPKTPDKDVIGAIQGWAPKNDLKISLPVTKFTLENGLTVLLLEDHAVPMVSYHTWY
RVGSRDESPGVTGAAHMLEHMMFKGAKKYDGKSFDRIFHENGITNNAFTTNDYTGFYENLPSSKLELVMDMEVDRMSSLL
ISPEDLKSEKEVVKEERRWRVDNNPMGLLRELMMGTIFKVHPYKWPVIGHMKDIEAYDSEKLRYFYNTFYVPNNAVLVVV
GDFNTSKVKSLIEKYYGKLPSRPLPERKYPSEPAQKVQQNATLRKDVQNTSFVVAYKSPKQGQPDMYALDLAANILGYGT
SSRLHKRLVYQKQTATSAYSYNYAMQDEGMFAVGVNLKPGQAPQEALDVVYNEIWKLRNQKVTEAELEKAKTQVMKDLVD
SLKTMDGKARALAVNEIVTGSYQSLFTDLEKYQAVTADDIKRVADKYTQQTQRSIITLEPKVKKEQ
>Mature_466_residues
MKRISTLLLGLSLSLSAHAVDPTPVPKTPDKDVIGAIQGWAPKNDLKISLPVTKFTLENGLTVLLLEDHAVPMVSYHTWY
RVGSRDESPGVTGAAHMLEHMMFKGAKKYDGKSFDRIFHENGITNNAFTTNDYTGFYENLPSSKLELVMDMEVDRMSSLL
ISPEDLKSEKEVVKEERRWRVDNNPMGLLRELMMGTIFKVHPYKWPVIGHMKDIEAYDSEKLRYFYNTFYVPNNAVLVVV
GDFNTSKVKSLIEKYYGKLPSRPLPERKYPSEPAQKVQQNATLRKDVQNTSFVVAYKSPKQGQPDMYALDLAANILGYGT
SSRLHKRLVYQKQTATSAYSYNYAMQDEGMFAVGVNLKPGQAPQEALDVVYNEIWKLRNQKVTEAELEKAKTQVMKDLVD
SLKTMDGKARALAVNEIVTGSYQSLFTDLEKYQAVTADDIKRVADKYTQQTQRSIITLEPKVKKEQ

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=364, Percent_Identity=23.0769230769231, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI94538354, Length=429, Percent_Identity=22.6107226107226, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI155969707, Length=232, Percent_Identity=25.4310344827586, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1787770, Length=259, Percent_Identity=27.4131274131274, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17553678, Length=410, Percent_Identity=25.1219512195122, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71999683, Length=204, Percent_Identity=26.4705882352941, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323192, Length=430, Percent_Identity=23.0232558139535, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321813, Length=406, Percent_Identity=23.1527093596059, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357875, Length=415, Percent_Identity=23.6144578313253, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646943, Length=415, Percent_Identity=23.6144578313253, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 52865; Mature: 52865

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRISTLLLGLSLSLSAHAVDPTPVPKTPDKDVIGAIQGWAPKNDLKISLPVTKFTLENG
CCHHHHHHHHHHHCCEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECEEEEECCCC
LTVLLLEDHAVPMVSYHTWYRVGSRDESPGVTGAAHMLEHMMFKGAKKYDGKSFDRIFHE
CEEEEECCCCCCEEEEHHEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
NGITNNAFTTNDYTGFYENLPSSKLELVMDMEVDRMSSLLISPEDLKSEKEVVKEERRWR
CCCCCCCEECCCCCHHHHCCCCCCEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHCCC
VDNNPMGLLRELMMGTIFKVHPYKWPVIGHMKDIEAYDSEKLRYFYNTFYVPNNAVLVVV
CCCCHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHCCCHHHEEEEEEEEECCCEEEEEE
GDFNTSKVKSLIEKYYGKLPSRPLPERKYPSEPAQKVQQNATLRKDVQNTSFVVAYKSPK
ECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCEEEEEECCCC
QGQPDMYALDLAANILGYGTSSRLHKRLVYQKQTATSAYSYNYAMQDEGMFAVGVNLKPG
CCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCC
QAPQEALDVVYNEIWKLRNQKVTEAELEKAKTQVMKDLVDSLKTMDGKARALAVNEIVTG
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHCC
SYQSLFTDLEKYQAVTADDIKRVADKYTQQTQRSIITLEPKVKKEQ
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEECCCCCCCC
>Mature Secondary Structure
MKRISTLLLGLSLSLSAHAVDPTPVPKTPDKDVIGAIQGWAPKNDLKISLPVTKFTLENG
CCHHHHHHHHHHHCCEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECEEEEECCCC
LTVLLLEDHAVPMVSYHTWYRVGSRDESPGVTGAAHMLEHMMFKGAKKYDGKSFDRIFHE
CEEEEECCCCCCEEEEHHEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
NGITNNAFTTNDYTGFYENLPSSKLELVMDMEVDRMSSLLISPEDLKSEKEVVKEERRWR
CCCCCCCEECCCCCHHHHCCCCCCEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHCCC
VDNNPMGLLRELMMGTIFKVHPYKWPVIGHMKDIEAYDSEKLRYFYNTFYVPNNAVLVVV
CCCCHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHCCCHHHEEEEEEEEECCCEEEEEE
GDFNTSKVKSLIEKYYGKLPSRPLPERKYPSEPAQKVQQNATLRKDVQNTSFVVAYKSPK
ECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCEEEEEECCCC
QGQPDMYALDLAANILGYGTSSRLHKRLVYQKQTATSAYSYNYAMQDEGMFAVGVNLKPG
CCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCC
QAPQEALDVVYNEIWKLRNQKVTEAELEKAKTQVMKDLVDSLKTMDGKARALAVNEIVTG
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHCC
SYQSLFTDLEKYQAVTADDIKRVADKYTQQTQRSIITLEPKVKKEQ
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]