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The map label for this gene is sppA [C]

Identifier: 42522622

GI number: 42522622

Start: 1013879

End: 1014847

Strand: Direct

Name: sppA [C]

Synonym: Bd1067

Alternate gene names: 42522622

Gene position: 1013879-1014847 (Clockwise)

Preceding gene: 42522621

Following gene: 42522623

Centisome position: 26.8

GC content: 50.57

Gene sequence:

>969_bases
ATGAAGGGCAGCTTTTTCAAAAAACTGATTATTATCTTTTTGGTGTTCGTAGGCCTTGGTGCCTTGTTGAAAATGAGCGG
GGACTTCTTCGGAAGTGAAGACAAGCGGGTCACTGCCAAAAACACCATTCTGCATCTGGAAATGAACGGCGTTATTCTTA
ACGGCAAGAAGTTCATTAAAAACCTAAAAAAGTACCGTGACGACGACAAGGTCAAAGCGATCCTGATCAGCATCAATTCT
CCGGGCGGCTCTGTGGGACCTTCCCAGGAACTGTTTGCTGAAATCAAACGCGTTCGTGATGAAATTAAAAAGCCGGTTGT
CTGTGTCAGCACGGGTGTGATGGCCAGCGGGGCTTATTATGCGGCCGTGGCTTGTGACAAGATCGTCGTGGCTCCAGGGG
CGCTGGTGGGTTCCATCGGTGTGATCATGGAATTTGCGAATCTGGAAAAGCTGTATGACTGGGCGAAGATCTCCCGTTAC
TCCATCACTTCCGGCAAGTTCAAGGACTCGGGTGCCGAGTACCGTCCCATGCGTGAAGATGAAAGAAGTCTGTTCCAGAG
CATGATTGATGAAGTCTATGCTCAGTTCAAAGGAACTGTGGCGACAGAGCGCAAGCTGAAAGAGGAAGTGGTTGCTGAGT
ACGCGGACGGCCGCGTGTTCACTGGTGCAACGGCGGTGAAAGTGGGCTTTGCCGATCAGGAAGGCTACTTTGACGATGCG
GTGAAACTGGCAGCAGAAATCGCCAAGCTGGGTGACAATTACGATGTCTTTGAAGTTCCCAAAAAGAAAGTCAGCATCTT
TGACCTTGGGGGCGGTGACACGGAAGACGACCTGAACAGCATGGCGGAATTCGCCGATGTTCTGAAAGGCAAATCTTTCG
GTGCGGATATGGAAGGCGCGATGAAATACATCCTGCGCGCGAAGTATCTGAATCAGCCGCTGATGTTGATGCCGGGTTAC
TGGGAGTAA

Upstream 100 bases:

>100_bases
CTGACCCGGCATTGACTGACAAGTTTTAAAGAGGGACCCTGGTAGGGTCCCTTTTTTTATTTGGAAAGGGACCTATTTCA
AACCGTTCGGGAGCGTTGGT

Downstream 100 bases:

>100_bases
TCCATGAAGTCCGTGGCTCTGTTTTTACTGACAGCGCTTTGTGTGAAGTGGGCGTGGGCAAATCCGATGGATCCGCGCCA
GCCGCAACCGTGGTTCGATG

Product: signal peptide peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKGSFFKKLIIIFLVFVGLGALLKMSGDFFGSEDKRVTAKNTILHLEMNGVILNGKKFIKNLKKYRDDDKVKAILISINS
PGGSVGPSQELFAEIKRVRDEIKKPVVCVSTGVMASGAYYAAVACDKIVVAPGALVGSIGVIMEFANLEKLYDWAKISRY
SITSGKFKDSGAEYRPMREDERSLFQSMIDEVYAQFKGTVATERKLKEEVVAEYADGRVFTGATAVKVGFADQEGYFDDA
VKLAAEIAKLGDNYDVFEVPKKKVSIFDLGGGDTEDDLNSMAEFADVLKGKSFGADMEGAMKYILRAKYLNQPLMLMPGY
WE

Sequences:

>Translated_322_residues
MKGSFFKKLIIIFLVFVGLGALLKMSGDFFGSEDKRVTAKNTILHLEMNGVILNGKKFIKNLKKYRDDDKVKAILISINS
PGGSVGPSQELFAEIKRVRDEIKKPVVCVSTGVMASGAYYAAVACDKIVVAPGALVGSIGVIMEFANLEKLYDWAKISRY
SITSGKFKDSGAEYRPMREDERSLFQSMIDEVYAQFKGTVATERKLKEEVVAEYADGRVFTGATAVKVGFADQEGYFDDA
VKLAAEIAKLGDNYDVFEVPKKKVSIFDLGGGDTEDDLNSMAEFADVLKGKSFGADMEGAMKYILRAKYLNQPLMLMPGY
WE
>Mature_322_residues
MKGSFFKKLIIIFLVFVGLGALLKMSGDFFGSEDKRVTAKNTILHLEMNGVILNGKKFIKNLKKYRDDDKVKAILISINS
PGGSVGPSQELFAEIKRVRDEIKKPVVCVSTGVMASGAYYAAVACDKIVVAPGALVGSIGVIMEFANLEKLYDWAKISRY
SITSGKFKDSGAEYRPMREDERSLFQSMIDEVYAQFKGTVATERKLKEEVVAEYADGRVFTGATAVKVGFADQEGYFDDA
VKLAAEIAKLGDNYDVFEVPKKKVSIFDLGGGDTEDDLNSMAEFADVLKGKSFGADMEGAMKYILRAKYLNQPLMLMPGY
WE

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=211, Percent_Identity=32.7014218009479, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787527, Length=168, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 35510; Mature: 35510

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGSFFKKLIIIFLVFVGLGALLKMSGDFFGSEDKRVTAKNTILHLEMNGVILNGKKFIK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEECCEEECCHHHHH
NLKKYRDDDKVKAILISINSPGGSVGPSQELFAEIKRVRDEIKKPVVCVSTGVMASGAYY
HHHHHCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCHHCCCEE
AAVACDKIVVAPGALVGSIGVIMEFANLEKLYDWAKISRYSITSGKFKDSGAEYRPMRED
EEEHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHH
ERSLFQSMIDEVYAQFKGTVATERKLKEEVVAEYADGRVFTGATAVKVGFADQEGYFDDA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCEEEEEECCCCCCCHHHH
VKLAAEIAKLGDNYDVFEVPKKKVSIFDLGGGDTEDDLNSMAEFADVLKGKSFGADMEGA
HHHHHHHHHCCCCCCCEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
MKYILRAKYLNQPLMLMPGYWE
HHHHHHHHHHCCCCEECCCCCC
>Mature Secondary Structure
MKGSFFKKLIIIFLVFVGLGALLKMSGDFFGSEDKRVTAKNTILHLEMNGVILNGKKFIK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEECCEEECCHHHHH
NLKKYRDDDKVKAILISINSPGGSVGPSQELFAEIKRVRDEIKKPVVCVSTGVMASGAYY
HHHHHCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCHHCCCEE
AAVACDKIVVAPGALVGSIGVIMEFANLEKLYDWAKISRYSITSGKFKDSGAEYRPMRED
EEEHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHH
ERSLFQSMIDEVYAQFKGTVATERKLKEEVVAEYADGRVFTGATAVKVGFADQEGYFDDA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCEEEEEECCCCCCCHHHH
VKLAAEIAKLGDNYDVFEVPKKKVSIFDLGGGDTEDDLNSMAEFADVLKGKSFGADMEGA
HHHHHHHHHCCCCCCCEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
MKYILRAKYLNQPLMLMPGYWE
HHHHHHHHHHCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]