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The map label for this gene is lysR [H]

Identifier: 42522567

GI number: 42522567

Start: 952347

End: 953285

Strand: Direct

Name: lysR [H]

Synonym: Bd1006

Alternate gene names: 42522567

Gene position: 952347-953285 (Clockwise)

Preceding gene: 42522564

Following gene: 42522570

Centisome position: 25.17

GC content: 51.33

Gene sequence:

>939_bases
TTGCGAAAGGTGACATATTCGGAATATACTGTTGCGTATATGGAACAATTAGATCTCAATCAGATACGCACATTCGTCAA
ACTTGTTCAAAGCGGCAGCTTCACCAAGGCGGCCGAGGTTTTGAAACAACCGAAGTCCCGCGTCAGCCGCAGGCTGTCAG
CCCTGGAAAAGGATCTGGGCGTGCAGTTGATATATCGCACCACGCGCCAGTTCCAGCTGACCGAAATGGGGCGCATTTAT
TATGAACGCGCTCGCGGTCTGATTGAAGGACTTGAAACCCTGACCGGAGAGGTCAGTGAATCGACCGCTGAAATCTCGGG
TGTGATTCGTGTCACGGCGTCGGATGATATGGGTGTGAAACACCTTCCTCTGATTGTGGATGAATTCACGCGCCAGTATC
CGCGAGTGCGATTTGATCTGTATCTGACTCAAGCTTATGTGGATCTGGTGAAGGAATCAGTCGATGTGGGGATCCGCATC
GGGAACCTGAAAGACAGCTCTTTGCGGGCGCGTAAGATCGGCACCGTGCGAAACTTGCTGGTGGCGTCCCCGGGCTTTTT
GGAGCGCTACCGTGTGGGGGAAGATCTGACAAAGCTTGCGGCGGCACCATTCTTGGGACTGACCCAGCAGCCAAAGCTTG
AGGTTGTTAGGTCTTCTGACGGAAAACGTCTGACGTTGAAAACCAATCCGATCGTCACCGCGAACAATCCGGAAATGCTT
CTGAATCTGGCTCGTCTGGGAAAAGGGTATGCTTTTGTGCCCGAGTTTTTGTGCAAGGATGAATTGCGTGACGGCCGCAT
GGTTCAGATTCATAAAAATCTGCGCGGAGATGAAGTCTCTGTCAGTCTGGTTTCACCCGACACGAAAGAAACGTCCCAGA
AGGTTAAGCGCTTCATGGACTTTGCCTACAAACGTTTGAAGGAAGTTTATTTCGCCTAA

Upstream 100 bases:

>100_bases
ATACCAGCCAAGGTAACCAGGGAACCAAGAATAAGTGCTTTCATGTGAATTTCTCCTTTTATGTTGTTTCAACGGAATTA
GTATCGTGCGTTTTTGATTA

Downstream 100 bases:

>100_bases
GAGAAAAGGCTTAAAAGCATCTTATAAAGACCGGAATACTCAAAGCGCAAAAGTGCCCAGACCGTCGCGCACCACAACGT
CGCCAAAAGGCCCATCAACA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRKVTYSEYTVAYMEQLDLNQIRTFVKLVQSGSFTKAAEVLKQPKSRVSRRLSALEKDLGVQLIYRTTRQFQLTEMGRIY
YERARGLIEGLETLTGEVSESTAEISGVIRVTASDDMGVKHLPLIVDEFTRQYPRVRFDLYLTQAYVDLVKESVDVGIRI
GNLKDSSLRARKIGTVRNLLVASPGFLERYRVGEDLTKLAAAPFLGLTQQPKLEVVRSSDGKRLTLKTNPIVTANNPEML
LNLARLGKGYAFVPEFLCKDELRDGRMVQIHKNLRGDEVSVSLVSPDTKETSQKVKRFMDFAYKRLKEVYFA

Sequences:

>Translated_312_residues
MRKVTYSEYTVAYMEQLDLNQIRTFVKLVQSGSFTKAAEVLKQPKSRVSRRLSALEKDLGVQLIYRTTRQFQLTEMGRIY
YERARGLIEGLETLTGEVSESTAEISGVIRVTASDDMGVKHLPLIVDEFTRQYPRVRFDLYLTQAYVDLVKESVDVGIRI
GNLKDSSLRARKIGTVRNLLVASPGFLERYRVGEDLTKLAAAPFLGLTQQPKLEVVRSSDGKRLTLKTNPIVTANNPEML
LNLARLGKGYAFVPEFLCKDELRDGRMVQIHKNLRGDEVSVSLVSPDTKETSQKVKRFMDFAYKRLKEVYFA
>Mature_312_residues
MRKVTYSEYTVAYMEQLDLNQIRTFVKLVQSGSFTKAAEVLKQPKSRVSRRLSALEKDLGVQLIYRTTRQFQLTEMGRIY
YERARGLIEGLETLTGEVSESTAEISGVIRVTASDDMGVKHLPLIVDEFTRQYPRVRFDLYLTQAYVDLVKESVDVGIRI
GNLKDSSLRARKIGTVRNLLVASPGFLERYRVGEDLTKLAAAPFLGLTQQPKLEVVRSSDGKRLTLKTNPIVTANNPEML
LNLARLGKGYAFVPEFLCKDELRDGRMVQIHKNLRGDEVSVSLVSPDTKETSQKVKRFMDFAYKRLKEVYFA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=31.7241379310345, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI145693193, Length=296, Percent_Identity=31.0810810810811, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1789639, Length=250, Percent_Identity=29.2, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=27.7966101694915, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789440, Length=252, Percent_Identity=27.3809523809524, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=22.4137931034483, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788481, Length=309, Percent_Identity=25.5663430420712, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=21.5017064846416, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788706, Length=189, Percent_Identity=27.5132275132275, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693105, Length=215, Percent_Identity=29.7674418604651, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082132, Length=173, Percent_Identity=29.4797687861272, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789173, Length=286, Percent_Identity=24.4755244755245, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=122, Percent_Identity=25.4098360655738, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790208, Length=258, Percent_Identity=25.5813953488372, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786713, Length=262, Percent_Identity=24.4274809160305, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788748, Length=254, Percent_Identity=26.3779527559055, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35487; Mature: 35487

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVTYSEYTVAYMEQLDLNQIRTFVKLVQSGSFTKAAEVLKQPKSRVSRRLSALEKDLG
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
VQLIYRTTRQFQLTEMGRIYYERARGLIEGLETLTGEVSESTAEISGVIRVTASDDMGVK
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHEEEEEEEEECCCCCCC
HLPLIVDEFTRQYPRVRFDLYLTQAYVDLVKESVDVGIRIGNLKDSSLRARKIGTVRNLL
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHH
VASPGFLERYRVGEDLTKLAAAPFLGLTQQPKLEVVRSSDGKRLTLKTNPIVTANNPEML
HCCCCHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHEECCCCCEEEEECCCEEECCCHHHH
LNLARLGKGYAFVPEFLCKDELRDGRMVQIHKNLRGDEVSVSLVSPDTKETSQKVKRFMD
HHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHH
FAYKRLKEVYFA
HHHHHHHHHHCC
>Mature Secondary Structure
MRKVTYSEYTVAYMEQLDLNQIRTFVKLVQSGSFTKAAEVLKQPKSRVSRRLSALEKDLG
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
VQLIYRTTRQFQLTEMGRIYYERARGLIEGLETLTGEVSESTAEISGVIRVTASDDMGVK
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHEEEEEEEEECCCCCCC
HLPLIVDEFTRQYPRVRFDLYLTQAYVDLVKESVDVGIRIGNLKDSSLRARKIGTVRNLL
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHH
VASPGFLERYRVGEDLTKLAAAPFLGLTQQPKLEVVRSSDGKRLTLKTNPIVTANNPEML
HCCCCHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHEECCCCCEEEEECCCEEECCCHHHH
LNLARLGKGYAFVPEFLCKDELRDGRMVQIHKNLRGDEVSVSLVSPDTKETSQKVKRFMD
HHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHH
FAYKRLKEVYFA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]