Click here to switch to the map view.

The map label for this gene is yafV [C]

Identifier: 42522510

GI number: 42522510

Start: 891533

End: 892363

Strand: Direct

Name: yafV [C]

Synonym: Bd0943

Alternate gene names: 42522510

Gene position: 891533-892363 (Clockwise)

Preceding gene: 42522509

Following gene: 42522511

Centisome position: 23.57

GC content: 54.39

Gene sequence:

>831_bases
ATGAGTTCAGAGTTGGTTGTCGCAGCAGTGCAAATGACTTCGGTCGATGATGTAACTACCAACTTGGCTCAGATGGAGGA
ACTCTTAAAAGAGGCCTTCAACGGCGCGCAACCGCGCTTTGTTTCCTTCCCTGAAAACTGTCTGTATTTGCGCTTGAAAG
AGGGCGAAAAGATCGAGGGGCTTACTCTCAGTCACCCGGCCTTTGCGCGTCTTTCCGAGCTGGCCAAACACTACAATACT
TATCTGCATCTGGGTTCGATCCCTCTTTATCTGGAGGGGCATCTTTACAATTCCTCGGCGCTGATCACTCCGGAAGGGGA
GGTACAGCCCACGTATCAGAAAATGCATCTGTTCGACATTCAGCTGGATGGTCAGGCCCCTTTGCGTGAATCCGATGTGT
TTCGCCACGGGCAAACCCCGAATGTGATCGATATCGACGGCTGGAAGGTGGGCGAGGCGATCTGCTATGATGTGCGTTTT
GCCGAACTGTTTTCGCAGTACGCCCGTCGTGAAGTGGATGTGATTTTACTTCCGGCGGCGTTCCTGGTGAAGACCGGCGA
GGCGCACTGGGAAATTCTGCTGCGGGCCCGTGCGATTGAGAATCAGTCTTATGTGATTGCCGCCGCTCAAGGGGGCACCC
ACACGGGTCTTCGTGGTGGCACCCGGGAAACCTATGGCCACAGCCTGATCATAGACCCTTGGGGGGCCGTTGTAGGCCAA
GTTGAAAAGCGCCAGCCTGGGGTTACGATCTCTAAATTCACACGCGAACGGATCGATTCTGTTCGACGCCAAATACCGAT
GAAGTTCCACCGCCGCCTTCCCGTAGGTTAG

Upstream 100 bases:

>100_bases
GTCAGAAAAAATCTGGAAGAAGCCAAATGGAGCTGCCGCGAAGTGAAAGAAGCACGCACTTCCAATGTTCTGATTAACAG
CGAAGATTAAGAGGTTCCTG

Downstream 100 bases:

>100_bases
GTGTTTACCCCCTCGAAAAACATGGGCTGGGCCGCGCCAGAGTTCTGGACTGAAAACCAGAATTCCTGCACTATTTCTAA
TGACAACTTTCTCAGTTAGC

Product: putative amidohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSSELVVAAVQMTSVDDVTTNLAQMEELLKEAFNGAQPRFVSFPENCLYLRLKEGEKIEGLTLSHPAFARLSELAKHYNT
YLHLGSIPLYLEGHLYNSSALITPEGEVQPTYQKMHLFDIQLDGQAPLRESDVFRHGQTPNVIDIDGWKVGEAICYDVRF
AELFSQYARREVDVILLPAAFLVKTGEAHWEILLRARAIENQSYVIAAAQGGTHTGLRGGTRETYGHSLIIDPWGAVVGQ
VEKRQPGVTISKFTRERIDSVRRQIPMKFHRRLPVG

Sequences:

>Translated_276_residues
MSSELVVAAVQMTSVDDVTTNLAQMEELLKEAFNGAQPRFVSFPENCLYLRLKEGEKIEGLTLSHPAFARLSELAKHYNT
YLHLGSIPLYLEGHLYNSSALITPEGEVQPTYQKMHLFDIQLDGQAPLRESDVFRHGQTPNVIDIDGWKVGEAICYDVRF
AELFSQYARREVDVILLPAAFLVKTGEAHWEILLRARAIENQSYVIAAAQGGTHTGLRGGTRETYGHSLIIDPWGAVVGQ
VEKRQPGVTISKFTRERIDSVRRQIPMKFHRRLPVG
>Mature_275_residues
SSELVVAAVQMTSVDDVTTNLAQMEELLKEAFNGAQPRFVSFPENCLYLRLKEGEKIEGLTLSHPAFARLSELAKHYNTY
LHLGSIPLYLEGHLYNSSALITPEGEVQPTYQKMHLFDIQLDGQAPLRESDVFRHGQTPNVIDIDGWKVGEAICYDVRFA
ELFSQYARREVDVILLPAAFLVKTGEAHWEILLRARAIENQSYVIAAAQGGTHTGLRGGTRETYGHSLIIDPWGAVVGQV
EKRQPGVTISKFTRERIDSVRRQIPMKFHRRLPVG

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=285, Percent_Identity=36.4912280701754, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI297632350, Length=285, Percent_Identity=36.4912280701754, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI297632348, Length=285, Percent_Identity=36.4912280701754, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI9910460, Length=278, Percent_Identity=34.5323741007194, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI297632346, Length=204, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI1786412, Length=183, Percent_Identity=28.4153005464481, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17556280, Length=271, Percent_Identity=35.0553505535055, Blast_Score=165, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322335, Length=302, Percent_Identity=32.1192052980132, Blast_Score=142, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6323383, Length=284, Percent_Identity=29.5774647887324, Blast_Score=119, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21355835, Length=282, Percent_Identity=31.5602836879433, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI17933642, Length=270, Percent_Identity=33.3333333333333, Blast_Score=144, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 31031; Mature: 30900

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSELVVAAVQMTSVDDVTTNLAQMEELLKEAFNGAQPRFVSFPENCLYLRLKEGEKIEG
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECCCCEECC
LTLSHPAFARLSELAKHYNTYLHLGSIPLYLEGHLYNSSALITPEGEVQPTYQKMHLFDI
EEECCHHHHHHHHHHHHHHCEEEECCCEEEEEEEEECCEEEECCCCCCCCCEEEEEEEEE
QLDGQAPLRESDVFRHGQTPNVIDIDGWKVGEAICYDVRFAELFSQYARREVDVILLPAA
EECCCCCCCCCHHHHCCCCCCEEECCCCCCCCHHEEHHHHHHHHHHHHHCCCCEEEECHH
FLVKTGEAHWEILLRARAIENQSYVIAAAQGGTHTGLRGGTRETYGHSLIIDPWGAVVGQ
HEEECCCHHHHHEEEHHHCCCCCEEEEEECCCCCCCCCCCCCHHCCCEEEECCHHHHHCC
VEKRQPGVTISKFTRERIDSVRRQIPMKFHRRLPVG
HHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCC
>Mature Secondary Structure 
SSELVVAAVQMTSVDDVTTNLAQMEELLKEAFNGAQPRFVSFPENCLYLRLKEGEKIEG
CCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECCCCEECC
LTLSHPAFARLSELAKHYNTYLHLGSIPLYLEGHLYNSSALITPEGEVQPTYQKMHLFDI
EEECCHHHHHHHHHHHHHHCEEEECCCEEEEEEEEECCEEEECCCCCCCCCEEEEEEEEE
QLDGQAPLRESDVFRHGQTPNVIDIDGWKVGEAICYDVRFAELFSQYARREVDVILLPAA
EECCCCCCCCCHHHHCCCCCCEEECCCCCCCCHHEEHHHHHHHHHHHHHCCCCEEEECHH
FLVKTGEAHWEILLRARAIENQSYVIAAAQGGTHTGLRGGTRETYGHSLIIDPWGAVVGQ
HEEECCCHHHHHEEEHHHCCCCCEEEEEECCCCCCCCCCCCCHHCCCEEEECCHHHHHCC
VEKRQPGVTISKFTRERIDSVRRQIPMKFHRRLPVG
HHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]