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The map label for this gene is mcp [H]

Identifier: 42522500

GI number: 42522500

Start: 884401

End: 885936

Strand: Direct

Name: mcp [H]

Synonym: Bd0932

Alternate gene names: 42522500

Gene position: 884401-885936 (Clockwise)

Preceding gene: 42522499

Following gene: 42522504

Centisome position: 23.38

GC content: 50.59

Gene sequence:

>1536_bases
ATGGGGTCGAATTTTAGTTTAAAAGGCAGACTTTTACTTCTTGGTGCTTTCATGTCCGCTATTCCGGTGCTGGTTGGAGG
TTTTGCATTCTACGGGATGCGAGAAGTCGCAAGCAGTTATGAGAAAGTTACCGACGGAGTGCTTCCCAATATTGAGTCCG
CGGATCAGATGTACATGAATTTTCGCGGTGTCAGAATCAGTTTGCGAAGCTTGGGTTTGCCGGGGCTGACGACAGAACAA
GAAGCTGACTTTATCAAAGATGTCGAAGCCAATATTGCCGAGTATGAAGTGCACAAACAGCAATATCTGCGTGTGAACTT
TAAGAAAGGCGAGCGGGAGCTCTATGAAAAGGTCGATGCTGCGTGGTTGGCATTTAAAGATCTTGGTGGGAAAGTCGTTC
AGTATTCCCGCACTGGTAAGCCAGAAGACCGTGCAAAGATGCTGGAAATATTCCTATATGACTGTCCCAAAGCGGCTAAA
GTCTATGACGACGCCATGACAAAGCTTGTGGCTTTCCAAAGAGCCAGCGGCGTTCAGTACGTGAAAGAGGCCCGATCGAC
AACGAGAACCACAGATGGAAGCATGGCGATAATTATCGCCCTGGGAATGATCGCAGGAGTCACTATAAGTGTGATGTTTG
CTCTGTCTCTTTCAAAATCAATTTCAGCCGTATCAGGGGATCTTGCTGAGGGGGCAAGTAATGTGACGGACGCTGCTGGA
CATATTGCACATTCCTCTCAATCTTTGTCTCAGGCAGCTTTGCAACAGGCGTCCTCGTTGGAAGAGACCGTGGCGACGAT
GGAGGAGCTGACGGCCATGGTTCGCGTTAATTCGGAAAACGCCAAGCAGGCAGCTTCTCTGGCATCATCAACCCGAGAGA
CGGCCATTAAAGGCGAAAAAGAGATCATAACGCTGATTCAGTCCATCCAGAGCATCTCATCGGATTCTAAAAAGATCGCG
GAGATCACTTCAGTAATTGACGATATTGCCTTTCAAACGAATCTGTTGGCCTTGAATGCGGCTGTGGAGGCCGCTCGGGC
TGGCGAACAGGGAAAAGGCTTTGCAGTTGTGGCAGAGGCTGTGCGCAGTCTGGCGCATCGAAGTGCTGAGTCTGCAAAGA
GCATCGCATCCCTGATTGATGACAGTGTTAAGAAGATCGATGCGGGCAGCCGACAAGCCAATCAGGGCGGTGAGGTTCTG
GCGGAAATCGTAAATGCAGTTAAAAAAGTTGCGGATCTTAACACGGAAATTGCGACGGCCAGTGAAGAGCAATCCCATGG
CATTGCCCAAATCGGTAAAGCAATGAATCAGCTGGATCAGATCACCCAGCAGAATGCTGCGGCCTCAGAGGAAGCGGCAG
CCGCAGCGGAACAGCTTTCTGCGGAGGCTGAATCTTTGCTGGGGAATGTGCGTGTTCTTAAAAAGGTTGTATCCGGCAAA
TCCGATCAGGCAGAGTCCGCGGCCGCGTCAGAGGGAACTGATGAGGTCCTGAAGGCCCAAGCGCTGCCGAAAAAACGCAC
TTTGCGTGCCGCCTGA

Upstream 100 bases:

>100_bases
TCTGCATTCGGCGGTCGCGCAAATGGAGCTGTTGTTACATTCAGCCACGTAGTTTTTAATTCGAATAGTTTTTATTTGTA
CTTTTCAAAGGAGCGTCAAA

Downstream 100 bases:

>100_bases
TCCGGCTTACCACACCCATGTCAGCTTTTTGTTTTGGTGGGCGATCAGCAGGTTCAGCATATAGATGCAATCCCAACCAT
TGGCGCGCTTCCAAGTTTGT

Product: hypothetical protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MGSNFSLKGRLLLLGAFMSAIPVLVGGFAFYGMREVASSYEKVTDGVLPNIESADQMYMNFRGVRISLRSLGLPGLTTEQ
EADFIKDVEANIAEYEVHKQQYLRVNFKKGERELYEKVDAAWLAFKDLGGKVVQYSRTGKPEDRAKMLEIFLYDCPKAAK
VYDDAMTKLVAFQRASGVQYVKEARSTTRTTDGSMAIIIALGMIAGVTISVMFALSLSKSISAVSGDLAEGASNVTDAAG
HIAHSSQSLSQAALQQASSLEETVATMEELTAMVRVNSENAKQAASLASSTRETAIKGEKEIITLIQSIQSISSDSKKIA
EITSVIDDIAFQTNLLALNAAVEAARAGEQGKGFAVVAEAVRSLAHRSAESAKSIASLIDDSVKKIDAGSRQANQGGEVL
AEIVNAVKKVADLNTEIATASEEQSHGIAQIGKAMNQLDQITQQNAAASEEAAAAAEQLSAEAESLLGNVRVLKKVVSGK
SDQAESAAASEGTDEVLKAQALPKKRTLRAA

Sequences:

>Translated_511_residues
MGSNFSLKGRLLLLGAFMSAIPVLVGGFAFYGMREVASSYEKVTDGVLPNIESADQMYMNFRGVRISLRSLGLPGLTTEQ
EADFIKDVEANIAEYEVHKQQYLRVNFKKGERELYEKVDAAWLAFKDLGGKVVQYSRTGKPEDRAKMLEIFLYDCPKAAK
VYDDAMTKLVAFQRASGVQYVKEARSTTRTTDGSMAIIIALGMIAGVTISVMFALSLSKSISAVSGDLAEGASNVTDAAG
HIAHSSQSLSQAALQQASSLEETVATMEELTAMVRVNSENAKQAASLASSTRETAIKGEKEIITLIQSIQSISSDSKKIA
EITSVIDDIAFQTNLLALNAAVEAARAGEQGKGFAVVAEAVRSLAHRSAESAKSIASLIDDSVKKIDAGSRQANQGGEVL
AEIVNAVKKVADLNTEIATASEEQSHGIAQIGKAMNQLDQITQQNAAASEEAAAAAEQLSAEAESLLGNVRVLKKVVSGK
SDQAESAAASEGTDEVLKAQALPKKRTLRAA
>Mature_510_residues
GSNFSLKGRLLLLGAFMSAIPVLVGGFAFYGMREVASSYEKVTDGVLPNIESADQMYMNFRGVRISLRSLGLPGLTTEQE
ADFIKDVEANIAEYEVHKQQYLRVNFKKGERELYEKVDAAWLAFKDLGGKVVQYSRTGKPEDRAKMLEIFLYDCPKAAKV
YDDAMTKLVAFQRASGVQYVKEARSTTRTTDGSMAIIIALGMIAGVTISVMFALSLSKSISAVSGDLAEGASNVTDAAGH
IAHSSQSLSQAALQQASSLEETVATMEELTAMVRVNSENAKQAASLASSTRETAIKGEKEIITLIQSIQSISSDSKKIAE
ITSVIDDIAFQTNLLALNAAVEAARAGEQGKGFAVVAEAVRSLAHRSAESAKSIASLIDDSVKKIDAGSRQANQGGEVLA
EIVNAVKKVADLNTEIATASEEQSHGIAQIGKAMNQLDQITQQNAAASEEAAAAAEQLSAEAESLLGNVRVLKKVVSGKS
DQAESAAASEGTDEVLKAQALPKKRTLRAA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=220, Percent_Identity=56.8181818181818, Blast_Score=231, Evalue=7e-62,
Organism=Escherichia coli, GI1788195, Length=231, Percent_Identity=51.0822510822511, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1788194, Length=267, Percent_Identity=46.4419475655431, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1787690, Length=258, Percent_Identity=45.7364341085271, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789453, Length=248, Percent_Identity=40.7258064516129, Blast_Score=172, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 54268; Mature: 54137

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSNFSLKGRLLLLGAFMSAIPVLVGGFAFYGMREVASSYEKVTDGVLPNIESADQMYMN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
FRGVRISLRSLGLPGLTTEQEADFIKDVEANIAEYEVHKQQYLRVNFKKGERELYEKVDA
HHHHEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHH
AWLAFKDLGGKVVQYSRTGKPEDRAKMLEIFLYDCPKAAKVYDDAMTKLVAFQRASGVQY
HHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHH
VKEARSTTRTTDGSMAIIIALGMIAGVTISVMFALSLSKSISAVSGDLAEGASNVTDAAG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHH
HIAHSSQSLSQAALQQASSLEETVATMEELTAMVRVNSENAKQAASLASSTRETAIKGEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHH
EIITLIQSIQSISSDSKKIAEITSVIDDIAFQTNLLALNAAVEAARAGEQGKGFAVVAEA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VRSLAHRSAESAKSIASLIDDSVKKIDAGSRQANQGGEVLAEIVNAVKKVADLNTEIATA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCC
SEEQSHGIAQIGKAMNQLDQITQQNAAASEEAAAAAEQLSAEAESLLGNVRVLKKVVSGK
CCHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SDQAESAAASEGTDEVLKAQALPKKRTLRAA
CCCHHHHHHCCCHHHHHHHHCCCCHHHCCCC
>Mature Secondary Structure 
GSNFSLKGRLLLLGAFMSAIPVLVGGFAFYGMREVASSYEKVTDGVLPNIESADQMYMN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
FRGVRISLRSLGLPGLTTEQEADFIKDVEANIAEYEVHKQQYLRVNFKKGERELYEKVDA
HHHHEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHH
AWLAFKDLGGKVVQYSRTGKPEDRAKMLEIFLYDCPKAAKVYDDAMTKLVAFQRASGVQY
HHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHH
VKEARSTTRTTDGSMAIIIALGMIAGVTISVMFALSLSKSISAVSGDLAEGASNVTDAAG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHH
HIAHSSQSLSQAALQQASSLEETVATMEELTAMVRVNSENAKQAASLASSTRETAIKGEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHH
EIITLIQSIQSISSDSKKIAEITSVIDDIAFQTNLLALNAAVEAARAGEQGKGFAVVAEA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VRSLAHRSAESAKSIASLIDDSVKKIDAGSRQANQGGEVLAEIVNAVKKVADLNTEIATA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCC
SEEQSHGIAQIGKAMNQLDQITQQNAAASEEAAAAAEQLSAEAESLLGNVRVLKKVVSGK
CCHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SDQAESAAASEGTDEVLKAQALPKKRTLRAA
CCCHHHHHHCCCHHHHHHHHCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]