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The map label for this gene is tolC [C]

Identifier: 42522458

GI number: 42522458

Start: 840003

End: 841307

Strand: Direct

Name: tolC [C]

Synonym: Bd0887

Alternate gene names: 42522458

Gene position: 840003-841307 (Clockwise)

Preceding gene: 42522457

Following gene: 42522459

Centisome position: 22.2

GC content: 52.72

Gene sequence:

>1305_bases
TTGCGAGGCCTCAGTAAGAATAATGGGATGCTACGAAAAACATCTCTTTCAATTGTGTGTCTTTCCGCAGTTCTTTCTTC
AGGTGCTTATTCTGCGACTTTGCAGGAGGCCTATCAGTCCGCTTTGCAGAAAAATGAGACTGTCGGAATCCAGAACGAAC
AAGTTCAACAAATTCGTGAGCGAGTAAAGCAGGTCCGGGGAGGAATGTTCCCGCAGATTAATGCCAACGCCACTTATTTC
ATGCAGCCGGCGCCCTCTGATCCGGTGGCAAAGCAGTTCTTCCCAGAGCGGCAGACCACAGTCGCCTTGACGGCGAATCA
GGTTTTGTTCCGGGGATTGCGTGAATTCGCAGCCGTCCGTCAGCAAAAAGATCTGGTGCAGTCCCAGGCAGAGATCCGCA
ATCAGGCGCTGATTCAGCTTTATCAGGATGTCACCAGTTCGTATTTGAACATCCTGACGCTGGAGCAGGATTTGGACAAC
ATCTCTGTTCAGCTGAAAATCTATGATGAACGGGTGAAAGAGCTGTCTTCGCGAGTGCGCCGGGGGGAATCCAGTTCATC
TGATGCGCTGACCGCACAAAGCAGCCAGGCTGCTTTAAACGCTGAATTTGAAATCATCACCGGAAATCTGAAAATGGCGC
GTGAAGCTTTTGCCTTCCTGACGGGCCTTCCCACAACAGAGCCTCTGACTGATCCGGAGCTGGCAAAATCAGTGAAAGTC
GCGCCCTTGCAGTCCTATCTGGACAGGATTGAAAGCCGGCATGATGTGAAGGCGGCCCGCAGCCAGCATCAGGCTATGGA
AGAGGAAGTCAGTATTGCCAAAGGGGCGCACTGGCCTTCGTTGGATCTGACCGGCAACTATTATTTCAAAAGACCGGATG
GTTTCAGCGAGGATCTGAACTGGGACGTGCAGTTGAAGCTGACGGTGCCACTGTTTGAGGGCGGCACGACTCAGTCCCGC
GTGCGAGAGGCCGCGTCCAAGCGCATTGAAGCGGACTTGCTGCTGTCCCGCTTGCGTCGGCAGGCTGATCAGGAAATCCG
TGCGTATTATGAAAACTTTAAAACACGCTTGAAGCAGGTCGAGGCTTTGGAAAAAGCCGGGGAGCTGTCCGAGCGCAACT
ACAAGGTTTTACAGAAAGACTATCGCCGTGGACTGGCTCGCAATATCGATGTGCAGATGGCTTTGACTGATTTCAGGATC
GCGGCCCGCGCCCTGGATCAGGCCCGTTTTGCGGCCCAGATGGAACTGGTGAAGCTGAAAGTGGCTTCGGCAGAAATTGA
AGTTCCGAAAGTGAAGGAAGACTAA

Upstream 100 bases:

>100_bases
CAAATAATTTTCACCAAACGTGGAAGATGGAAAGGCCGAAGGAAACTTCGGCCTTTTTTTATCTGGCCCAACGCGCCTTT
AAAATAATCTGTCTTGAAAA

Downstream 100 bases:

>100_bases
GATGACATTGTCTGATTTATCTATTCGCAGACCCGTCTTTGCCTGGATGTTGATGTTCGGTCTGATCGTCTTTGGGGCGA
TCAGCTTTATGCGCATGGGC

Product: outer membrane export factor

Products: NA

Alternate protein names: LC Family Type I Secretion Outer Membrane Protein; Type I Secretion Outer Membrane Efflux Protein; Outer Membrane Export Factor; Type I Secretion Outer Membrane Protein lC; Cation/Multidrug Efflux System Outer Membrane Porin

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRGLSKNNGMLRKTSLSIVCLSAVLSSGAYSATLQEAYQSALQKNETVGIQNEQVQQIRERVKQVRGGMFPQINANATYF
MQPAPSDPVAKQFFPERQTTVALTANQVLFRGLREFAAVRQQKDLVQSQAEIRNQALIQLYQDVTSSYLNILTLEQDLDN
ISVQLKIYDERVKELSSRVRRGESSSSDALTAQSSQAALNAEFEIITGNLKMAREAFAFLTGLPTTEPLTDPELAKSVKV
APLQSYLDRIESRHDVKAARSQHQAMEEEVSIAKGAHWPSLDLTGNYYFKRPDGFSEDLNWDVQLKLTVPLFEGGTTQSR
VREAASKRIEADLLLSRLRRQADQEIRAYYENFKTRLKQVEALEKAGELSERNYKVLQKDYRRGLARNIDVQMALTDFRI
AARALDQARFAAQMELVKLKVASAEIEVPKVKED

Sequences:

>Translated_434_residues
MRGLSKNNGMLRKTSLSIVCLSAVLSSGAYSATLQEAYQSALQKNETVGIQNEQVQQIRERVKQVRGGMFPQINANATYF
MQPAPSDPVAKQFFPERQTTVALTANQVLFRGLREFAAVRQQKDLVQSQAEIRNQALIQLYQDVTSSYLNILTLEQDLDN
ISVQLKIYDERVKELSSRVRRGESSSSDALTAQSSQAALNAEFEIITGNLKMAREAFAFLTGLPTTEPLTDPELAKSVKV
APLQSYLDRIESRHDVKAARSQHQAMEEEVSIAKGAHWPSLDLTGNYYFKRPDGFSEDLNWDVQLKLTVPLFEGGTTQSR
VREAASKRIEADLLLSRLRRQADQEIRAYYENFKTRLKQVEALEKAGELSERNYKVLQKDYRRGLARNIDVQMALTDFRI
AARALDQARFAAQMELVKLKVASAEIEVPKVKED
>Mature_434_residues
MRGLSKNNGMLRKTSLSIVCLSAVLSSGAYSATLQEAYQSALQKNETVGIQNEQVQQIRERVKQVRGGMFPQINANATYF
MQPAPSDPVAKQFFPERQTTVALTANQVLFRGLREFAAVRQQKDLVQSQAEIRNQALIQLYQDVTSSYLNILTLEQDLDN
ISVQLKIYDERVKELSSRVRRGESSSSDALTAQSSQAALNAEFEIITGNLKMAREAFAFLTGLPTTEPLTDPELAKSVKV
APLQSYLDRIESRHDVKAARSQHQAMEEEVSIAKGAHWPSLDLTGNYYFKRPDGFSEDLNWDVQLKLTVPLFEGGTTQSR
VREAASKRIEADLLLSRLRRQADQEIRAYYENFKTRLKQVEALEKAGELSERNYKVLQKDYRRGLARNIDVQMALTDFRI
AARALDQARFAAQMELVKLKVASAEIEVPKVKED

Specific function: Required For Proper Expression Of Outer Membrane Protein Genes Such As Ompf, Nmpc, Protein 2, Hemolysin, Colicin V, Or Colicin E1. May Be Specialized For Signal Sequence Independent, Extracellular Secretion In Gram-Negative Bacteria. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48958; Mature: 48958

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLSKNNGMLRKTSLSIVCLSAVLSSGAYSATLQEAYQSALQKNETVGIQNEQVQQIRE
CCCCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
RVKQVRGGMFPQINANATYFMQPAPSDPVAKQFFPERQTTVALTANQVLFRGLREFAAVR
HHHHHHCCCCCEECCCEEEEECCCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHH
QQKDLVQSQAEIRNQALIQLYQDVTSSYLNILTLEQDLDNISVQLKIYDERVKELSSRVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHH
RGESSSSDALTAQSSQAALNAEFEIITGNLKMAREAFAFLTGLPTTEPLTDPELAKSVKV
CCCCCCCCCEECCCCHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCH
APLQSYLDRIESRHDVKAARSQHQAMEEEVSIAKGAHWPSLDLTGNYYFKRPDGFSEDLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCC
WDVQLKLTVPLFEGGTTQSRVREAASKRIEADLLLSRLRRQADQEIRAYYENFKTRLKQV
CEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALEKAGELSERNYKVLQKDYRRGLARNIDVQMALTDFRIAARALDQARFAAQMELVKLK
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHE
VASAEIEVPKVKED
EHHCEEECCCCCCC
>Mature Secondary Structure
MRGLSKNNGMLRKTSLSIVCLSAVLSSGAYSATLQEAYQSALQKNETVGIQNEQVQQIRE
CCCCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
RVKQVRGGMFPQINANATYFMQPAPSDPVAKQFFPERQTTVALTANQVLFRGLREFAAVR
HHHHHHCCCCCEECCCEEEEECCCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHH
QQKDLVQSQAEIRNQALIQLYQDVTSSYLNILTLEQDLDNISVQLKIYDERVKELSSRVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHH
RGESSSSDALTAQSSQAALNAEFEIITGNLKMAREAFAFLTGLPTTEPLTDPELAKSVKV
CCCCCCCCCEECCCCHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCH
APLQSYLDRIESRHDVKAARSQHQAMEEEVSIAKGAHWPSLDLTGNYYFKRPDGFSEDLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCC
WDVQLKLTVPLFEGGTTQSRVREAASKRIEADLLLSRLRRQADQEIRAYYENFKTRLKQV
CEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALEKAGELSERNYKVLQKDYRRGLARNIDVQMALTDFRIAARALDQARFAAQMELVKLK
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHE
VASAEIEVPKVKED
EHHCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA