Click here to switch to the map view.

The map label for this gene is kdsC [H]

Identifier: 42522403

GI number: 42522403

Start: 776567

End: 777097

Strand: Direct

Name: kdsC [H]

Synonym: Bd0827

Alternate gene names: 42522403

Gene position: 776567-777097 (Clockwise)

Preceding gene: 42522402

Following gene: 42522404

Centisome position: 20.53

GC content: 46.52

Gene sequence:

>531_bases
TTGTCTTTTATTTTTCACAATGATTCAGTGGCATTAGAAATTTCAAAACTTAAAAATATCAAGATGTTGGTTCTCGACGT
TGATGGCGTATTAACTGACACACGCGTGTGGTTTGATGGCACTGAATGGCGCCGCTTTTATTCCATCCGGGATGGCGTGG
GCATCAAACGTCTGATGGAATCCGGTTACAAAATAGCAGTGATTACAGGCAGTAAGGCAGAGGATATTCGCGCTCGCGTG
AAGGCTCTTGGTATTCAGTATTTCTATGAGGGTGCTCTCGACAAAGAGCCCTCTTTCTTGCAGCTGCAGCAGGAATCCGG
CCTGAAGCCTGAAGAGATGGCGTATGTCGGTGATGATATTTTTGATATTCCCATGATCGAGGCGGTGGCATTTGGAGCAA
CGGTTCCAGAGGCGGTCGATGAAGTTATGGAAGTGGCTGATTATGTGACCCGCAGACCTGGTGGTTTGGGGGCTGTTCGT
GAAGTTTGTGATTACATCTATAAATACGGTGCATTTGCATCGGGTAGGTAA

Upstream 100 bases:

>100_bases
TCCGTTTGCAGCAAAGAGTGAACGAACTCGAGTCAGCCCGACCTTAGTCGGTGTGTCCACACAACCCTAAGTCCTGTATC
AGAGTGGGGCACTTGCTCCA

Downstream 100 bases:

>100_bases
GAAATGCTAAAAAATGGTTTCAAGGCCGCTCTCATCATAGTTCTTGCGCTGATGCTGCATAAGGCGGCTTTTGCGGAAGT
GGTGAATCTTCCTACAGAGG

Product: hypothetical protein

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MSFIFHNDSVALEISKLKNIKMLVLDVDGVLTDTRVWFDGTEWRRFYSIRDGVGIKRLMESGYKIAVITGSKAEDIRARV
KALGIQYFYEGALDKEPSFLQLQQESGLKPEEMAYVGDDIFDIPMIEAVAFGATVPEAVDEVMEVADYVTRRPGGLGAVR
EVCDYIYKYGAFASGR

Sequences:

>Translated_176_residues
MSFIFHNDSVALEISKLKNIKMLVLDVDGVLTDTRVWFDGTEWRRFYSIRDGVGIKRLMESGYKIAVITGSKAEDIRARV
KALGIQYFYEGALDKEPSFLQLQQESGLKPEEMAYVGDDIFDIPMIEAVAFGATVPEAVDEVMEVADYVTRRPGGLGAVR
EVCDYIYKYGAFASGR
>Mature_175_residues
SFIFHNDSVALEISKLKNIKMLVLDVDGVLTDTRVWFDGTEWRRFYSIRDGVGIKRLMESGYKIAVITGSKAEDIRARVK
ALGIQYFYEGALDKEPSFLQLQQESGLKPEEMAYVGDDIFDIPMIEAVAFGATVPEAVDEVMEVADYVTRRPGGLGAVRE
VCDYIYKYGAFASGR

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=153, Percent_Identity=27.4509803921569, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI2367202, Length=155, Percent_Identity=43.2258064516129, Blast_Score=128, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19740; Mature: 19609

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIFHNDSVALEISKLKNIKMLVLDVDGVLTDTRVWFDGTEWRRFYSIRDGVGIKRLME
CCEEEECCCEEEEEECCCCEEEEEEECCCEEECCEEEECCHHHHHHHHHHCCCCHHHHHH
SGYKIAVITGSKAEDIRARVKALGIQYFYEGALDKEPSFLQLQQESGLKPEEMAYVGDDI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHCCCCHHHHHHCCCCC
FDIPMIEAVAFGATVPEAVDEVMEVADYVTRRPGGLGAVREVCDYIYKYGAFASGR
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SFIFHNDSVALEISKLKNIKMLVLDVDGVLTDTRVWFDGTEWRRFYSIRDGVGIKRLME
CEEEECCCEEEEEECCCCEEEEEEECCCEEECCEEEECCHHHHHHHHHHCCCCHHHHHH
SGYKIAVITGSKAEDIRARVKALGIQYFYEGALDKEPSFLQLQQESGLKPEEMAYVGDDI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHCCCCHHHHHHCCCCC
FDIPMIEAVAFGATVPEAVDEVMEVADYVTRRPGGLGAVREVCDYIYKYGAFASGR
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]