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The map label for this gene is ppaT

Identifier: 42522214

GI number: 42522214

Start: 581280

End: 581762

Strand: Direct

Name: ppaT

Synonym: Bd0623

Alternate gene names: 42522214

Gene position: 581280-581762 (Clockwise)

Preceding gene: 42522213

Following gene: 42522215

Centisome position: 15.37

GC content: 48.45

Gene sequence:

>483_bases
ATGAGTAAAATTGCCGTTTACCCAGGAAGCTTTGACCCCATCACAATGGGGCATGTGGATATCATCAACCGTATTTCCCC
TTTGTATGACGAAGTCATCGTGTTGGTTGCACAATCTTCACAGAAGCAAAGCATGTTTTCTGTTGAAGAACGAAAGACTT
TGATCGAAAAAGCCTTGTCCCATCTGAAAAACGTCAAAGTCGATATCTTTGGCGGCCTGACGGTGGAGTACATGAAAAAA
GCCAAAGCCCAGGTGATCGTACGGGGCTTGCGTGCGGTTTCGGATTTCGAGTACGAGATGACCATGGCGAACATGAATCG
CAAGTTGGCGCCGGACTTTGAAACCCTTTTGGTCTTTGCCAGCCCCGAGTTCTATTATATTTCTTCGCGCGGGGTGAAAG
AGGTCGCCATCAACGGTGGCGCCTTGAAAGGCCTGGTGCCGGACGTGGTGGTCGAAGCCATGGAGAATAAAATCAGAAAG
TAA

Upstream 100 bases:

>100_bases
CGTTACAGCAAAAAAGAATATGGCGATAAAATCCTAAGTCTGTTCTGCCACGAAAGTGCCTTGGAGCAGGATGAAGAACC
GGCAGCCGAAGAGGAACATC

Downstream 100 bases:

>100_bases
GGAGCGAATTTTGATTCAGCTTTCCAAACGAGCGCAAAATCTGAAGCCTTCTCCAACTCTGTTTCTGGTGGCAAAGGCCA
AAGAGCTGGCTGCCCAGGGG

Product: hypothetical protein

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKK
AKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

Sequences:

>Translated_160_residues
MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKK
AKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK
>Mature_159_residues
SKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKA
KAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=158, Percent_Identity=45.5696202531646, Blast_Score=154, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_BDEBA (Q6MQ60)

Other databases:

- EMBL:   BX842647
- RefSeq:   NP_967594.1
- ProteinModelPortal:   Q6MQ60
- SMR:   Q6MQ60
- GeneID:   2733543
- GenomeReviews:   BX842601_GR
- KEGG:   bba:Bd0623
- NMPDR:   fig|264462.1.peg.564
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q6MQ60
- BioCyc:   BBAC264462:BD0623-MONOMER
- BRENDA:   2.7.7.3
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17890; Mature: 17759

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALS
CCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
HLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFA
HHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEE
SPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK
CCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALS
CCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
HLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFA
HHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEE
SPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK
CCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA