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The map label for this gene is ppa [H]

Identifier: 42522167

GI number: 42522167

Start: 529122

End: 529682

Strand: Direct

Name: ppa [H]

Synonym: Bd0571

Alternate gene names: 42522167

Gene position: 529122-529682 (Clockwise)

Preceding gene: 42522166

Following gene: 42522168

Centisome position: 13.99

GC content: 50.98

Gene sequence:

>561_bases
ATGAATCCCTGGCATGATTTGAGTCCCGGAGAAAAAGCTCCGGAAGTGGTGACCGCGCTGATTGAAATTCCCGCAGGATC
CAAAACCAAGTTCGAGCTGGACAAGGTTTCAGGCCTTCTGAAAGTGGACCGGGTGCTTTACAGCTCGGTTCACTATCCTG
CCAACTATGGTTTTATTCCGCGCACTTATTGTGGTGATCATGACCCGCTGGACATTCTGGTGTTGGGTCAGGCCCAAGTG
TATCCGCTCAGTATTATGCGGGCCCGTCCGGTGGGTTGCATGCGCATGCTCGATCAGGGCGAGATGGACGACAAGGTCAT
TGCGGTTCATGAAGATGATCCCGAGATGGCGCACATCCATTCCATCAAGGATCTGGCGCCGCACCAGTTGAAAGAAATCC
GCAACTTCTTTGAAATCTACAAGGGTCTTGAAAACAAAAAGGTCGAAGTCGAAGGCTTCCACGATCTGCCGGAAACCCTG
AAGATCATCAAAGAGGCCTTTGATCTGTACAAACAGGAACGAACGACGCTGTTGAAGCAGTCTGAAAGCGGCCATGATTA
A

Upstream 100 bases:

>100_bases
TCAAACGCGCCCAGCGCCGTTCCGATGCCGAGATGAAACAGATCCAGTCTGAAATCATCAAACACCTGGAAGCGATGAAA
TAACTTAATACGGAGGCCCT

Downstream 100 bases:

>100_bases
AGAAACAGCCCACGACATCGTTGCTGGCGGTATCTATCAGCATTATTCCGGCAAACAATACCGTGTGATCGGCGTCGGCC
GGCACAGTGAAAGCCTGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MNPWHDLSPGEKAPEVVTALIEIPAGSKTKFELDKVSGLLKVDRVLYSSVHYPANYGFIPRTYCGDHDPLDILVLGQAQV
YPLSIMRARPVGCMRMLDQGEMDDKVIAVHEDDPEMAHIHSIKDLAPHQLKEIRNFFEIYKGLENKKVEVEGFHDLPETL
KIIKEAFDLYKQERTTLLKQSESGHD

Sequences:

>Translated_186_residues
MNPWHDLSPGEKAPEVVTALIEIPAGSKTKFELDKVSGLLKVDRVLYSSVHYPANYGFIPRTYCGDHDPLDILVLGQAQV
YPLSIMRARPVGCMRMLDQGEMDDKVIAVHEDDPEMAHIHSIKDLAPHQLKEIRNFFEIYKGLENKKVEVEGFHDLPETL
KIIKEAFDLYKQERTTLLKQSESGHD
>Mature_186_residues
MNPWHDLSPGEKAPEVVTALIEIPAGSKTKFELDKVSGLLKVDRVLYSSVHYPANYGFIPRTYCGDHDPLDILVLGQAQV
YPLSIMRARPVGCMRMLDQGEMDDKVIAVHEDDPEMAHIHSIKDLAPHQLKEIRNFFEIYKGLENKKVEVEGFHDLPETL
KIIKEAFDLYKQERTTLLKQSESGHD

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Homo sapiens, GI11056044, Length=201, Percent_Identity=29.8507462686567, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI29171702, Length=195, Percent_Identity=25.6410256410256, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790673, Length=173, Percent_Identity=39.3063583815029, Blast_Score=104, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319483, Length=193, Percent_Identity=28.4974093264249, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323923, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 21182; Mature: 21182

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPWHDLSPGEKAPEVVTALIEIPAGSKTKFELDKVSGLLKVDRVLYSSVHYPANYGFIP
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RTYCGDHDPLDILVLGQAQVYPLSIMRARPVGCMRMLDQGEMDDKVIAVHEDDPEMAHIH
CCCCCCCCCEEEEEECCCCCCHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHH
SIKDLAPHQLKEIRNFFEIYKGLENKKVEVEGFHDLPETLKIIKEAFDLYKQERTTLLKQ
HHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
SESGHD
CCCCCC
>Mature Secondary Structure
MNPWHDLSPGEKAPEVVTALIEIPAGSKTKFELDKVSGLLKVDRVLYSSVHYPANYGFIP
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RTYCGDHDPLDILVLGQAQVYPLSIMRARPVGCMRMLDQGEMDDKVIAVHEDDPEMAHIH
CCCCCCCCCEEEEEECCCCCCHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHH
SIKDLAPHQLKEIRNFFEIYKGLENKKVEVEGFHDLPETLKIIKEAFDLYKQERTTLLKQ
HHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
SESGHD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA