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The map label for this gene is pgpA [H]

Identifier: 42522115

GI number: 42522115

Start: 478397

End: 478882

Strand: Direct

Name: pgpA [H]

Synonym: Bd0509

Alternate gene names: 42522115

Gene position: 478397-478882 (Clockwise)

Preceding gene: 42522114

Following gene: 42522116

Centisome position: 12.65

GC content: 47.94

Gene sequence:

>486_bases
ATGGTGACAAACTTTCTGATACAACTTGCGACTCTGTTTGGTGTGGGCCGTTTCCCGAAAGGGCCGGGCACGATGGGCAC
CCTGGCGACTATTCCGATTGTCATTCTTTTAAGCAAATTGGGCCCTTTGGTTTACATGGGAGTAGTGGTTTTGCTGCTCC
CTGTCGGAATTGCGGCCTGCGAGGCTTACGAGCGTTCCAAGGGTGGTCATGATCACAAAGAGATCGTAATTGATGAGGTT
TTGGGTTTTCTGATCACCATGGTTTGGATGCCGATGACATGGCAGGCCATTTTAATCGGTTTTGCCCTGTTCAGAGTGCT
GGACATCACAAAGCCTTTATTCATAGGATATTTAGATAAGAAGATCCAAGGAGGACTTGGAGTGATGATCGATGACGTGG
CCGCGGGGATAATTGCGAGCCTCATCATGCAAGTGATCTACACTCAAACCAATTGGTTGGGCTCGCAAATTGTGGTGATT
AACTAA

Upstream 100 bases:

>100_bases
CGCAGTCCGTGAATCCGGGCCGGTTTCCGAACCGGCTTTAATGCTCTGACGCTTCTCATTCTGCATTGCAAGGCCTACGG
GTCCGGCGTACCTCATCGGT

Downstream 100 bases:

>100_bases
ATGTCACTTAACAACGAAAAGCTTCAAGAACTCATTCGATCCCTTCGCGACCAAAAACTCACAGTGGGTTTTGCGGAAAG
TTGTACTGGAGGTGCACTTT

Product: phosphatidylglycerophosphatase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MVTNFLIQLATLFGVGRFPKGPGTMGTLATIPIVILLSKLGPLVYMGVVVLLLPVGIAACEAYERSKGGHDHKEIVIDEV
LGFLITMVWMPMTWQAILIGFALFRVLDITKPLFIGYLDKKIQGGLGVMIDDVAAGIIASLIMQVIYTQTNWLGSQIVVI
N

Sequences:

>Translated_161_residues
MVTNFLIQLATLFGVGRFPKGPGTMGTLATIPIVILLSKLGPLVYMGVVVLLLPVGIAACEAYERSKGGHDHKEIVIDEV
LGFLITMVWMPMTWQAILIGFALFRVLDITKPLFIGYLDKKIQGGLGVMIDDVAAGIIASLIMQVIYTQTNWLGSQIVVI
N
>Mature_161_residues
MVTNFLIQLATLFGVGRFPKGPGTMGTLATIPIVILLSKLGPLVYMGVVVLLLPVGIAACEAYERSKGGHDHKEIVIDEV
LGFLITMVWMPMTWQAILIGFALFRVLDITKPLFIGYLDKKIQGGLGVMIDDVAAGIIASLIMQVIYTQTNWLGSQIVVI
N

Specific function: One of the three phospholipid phosphatases, specifically hydrolyzes phosphatidylglycerophosphate [H]

COG id: COG1267

COG function: function code I; Phosphatidylglycerophosphatase A and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786620, Length=146, Percent_Identity=41.0958904109589, Blast_Score=109, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007686 [H]

Pfam domain/function: PF04608 PgpA [H]

EC number: =3.1.3.27 [H]

Molecular weight: Translated: 17472; Mature: 17472

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTNFLIQLATLFGVGRFPKGPGTMGTLATIPIVILLSKLGPLVYMGVVVLLLPVGIAAC
CHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAYERSKGGHDHKEIVIDEVLGFLITMVWMPMTWQAILIGFALFRVLDITKPLFIGYLDK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIQGGLGVMIDDVAAGIIASLIMQVIYTQTNWLGSQIVVIN
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MVTNFLIQLATLFGVGRFPKGPGTMGTLATIPIVILLSKLGPLVYMGVVVLLLPVGIAAC
CHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAYERSKGGHDHKEIVIDEVLGFLITMVWMPMTWQAILIGFALFRVLDITKPLFIGYLDK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIQGGLGVMIDDVAAGIIASLIMQVIYTQTNWLGSQIVVIN
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2846510; 9278503 [H]