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The map label for this gene is fabG [H]

Identifier: 42522019

GI number: 42522019

Start: 381901

End: 382653

Strand: Direct

Name: fabG [H]

Synonym: Bd0405

Alternate gene names: 42522019

Gene position: 381901-382653 (Clockwise)

Preceding gene: 42522018

Following gene: 42522020

Centisome position: 10.1

GC content: 47.68

Gene sequence:

>753_bases
ATGGAATTTAATTTGAGAGAACGAACGGCGCTCATTGTTGGACCTTTTACTTCAACCGTTCAAAGTCTGGTGATGGGTTT
GACCCAAATGGGTTCTGACTGCGTCCTGCTGGATTTTGATAACAGCGCCAGTCAGCGTTTTTGCAATCAGATCAATGATG
CCCGTGAAATCAACCCTAAGTTCGGTCGTGCGTTGGGGATCAAGTCCCCGATGAAAACTGCGGAAGACATCAAGGATGCG
GTGGGCTCGGCGGCTCACGCTTTTGGCAGTGTCGATCTGTTCATTGATGCTCAAGCCTACAATAAACCCAATCGTTATAA
AATCGGCGACAGCATTGATTATCTGGATGATGAAATCCAGCATAACTTTAAAGCTTCGGTGATGCTGACCCATGCGGTGT
TAAACTTCCTTAAAAACCGCAAGCGCGGCCGTATTCTTTATCTTTTGAATGAAGTTTACCCGGATCCGATTCTGGCGGGT
TCCCGCGGGGCGCTGGTGCCGTTTGCACAAAGTCTGTCCAAACAGGTGGCTGAACACAACATTACCGTGAATGTACTGAA
GCTGGGTTTGACTGAAGAATTCATTCTGGCGATGCACCCGGAAGCCAAATCCATCAAAGAAGCGGTTGAAAATCTGAAGG
TGAAAGAACCACACTTGCGCATCACGGAACCCGAGAAAATCACCAACACCGTGACCTATCTGGTTAGTCAGTTTGGTGCG
GCGGTGAATGGTCAGGTTATTTCTTTAAGTTAG

Upstream 100 bases:

>100_bases
GTTCTGCTTGTATTGGCGGCGGTCAGGGTATTGCGATCATCATCGAAAGAATCTAACAGCGAGGGGCCGCCAAGGACTGC
GGCCTCTGGAACAGGGACTC

Downstream 100 bases:

>100_bases
GTTATTAAAATGCAGGCAACCGGTAAAATCACAATCACCCCTCATTCTCCGATGTTTCAGTGGTGGGATTTCATCCCGCA
CTACACCCTGAAGGACTATT

Product: 3-ketoacyl-acyl carrier protein reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MEFNLRERTALIVGPFTSTVQSLVMGLTQMGSDCVLLDFDNSASQRFCNQINDAREINPKFGRALGIKSPMKTAEDIKDA
VGSAAHAFGSVDLFIDAQAYNKPNRYKIGDSIDYLDDEIQHNFKASVMLTHAVLNFLKNRKRGRILYLLNEVYPDPILAG
SRGALVPFAQSLSKQVAEHNITVNVLKLGLTEEFILAMHPEAKSIKEAVENLKVKEPHLRITEPEKITNTVTYLVSQFGA
AVNGQVISLS

Sequences:

>Translated_250_residues
MEFNLRERTALIVGPFTSTVQSLVMGLTQMGSDCVLLDFDNSASQRFCNQINDAREINPKFGRALGIKSPMKTAEDIKDA
VGSAAHAFGSVDLFIDAQAYNKPNRYKIGDSIDYLDDEIQHNFKASVMLTHAVLNFLKNRKRGRILYLLNEVYPDPILAG
SRGALVPFAQSLSKQVAEHNITVNVLKLGLTEEFILAMHPEAKSIKEAVENLKVKEPHLRITEPEKITNTVTYLVSQFGA
AVNGQVISLS
>Mature_250_residues
MEFNLRERTALIVGPFTSTVQSLVMGLTQMGSDCVLLDFDNSASQRFCNQINDAREINPKFGRALGIKSPMKTAEDIKDA
VGSAAHAFGSVDLFIDAQAYNKPNRYKIGDSIDYLDDEIQHNFKASVMLTHAVLNFLKNRKRGRILYLLNEVYPDPILAG
SRGALVPFAQSLSKQVAEHNITVNVLKLGLTEEFILAMHPEAKSIKEAVENLKVKEPHLRITEPEKITNTVTYLVSQFGA
AVNGQVISLS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27665; Mature: 27665

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFNLRERTALIVGPFTSTVQSLVMGLTQMGSDCVLLDFDNSASQRFCNQINDAREINPK
CCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCHH
FGRALGIKSPMKTAEDIKDAVGSAAHAFGSVDLFIDAQAYNKPNRYKIGDSIDYLDDEIQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCEECCCCHHHHHHHHH
HNFKASVMLTHAVLNFLKNRKRGRILYLLNEVYPDPILAGSRGALVPFAQSLSKQVAEHN
CCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCEECCCCCCHHHHHHHHHHHHHHCC
ITVNVLKLGLTEEFILAMHPEAKSIKEAVENLKVKEPHLRITEPEKITNTVTYLVSQFGA
CEEEEEEECCCHHHHEEECCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHCC
AVNGQVISLS
HHCCEEEEEC
>Mature Secondary Structure
MEFNLRERTALIVGPFTSTVQSLVMGLTQMGSDCVLLDFDNSASQRFCNQINDAREINPK
CCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCHH
FGRALGIKSPMKTAEDIKDAVGSAAHAFGSVDLFIDAQAYNKPNRYKIGDSIDYLDDEIQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCEECCCCHHHHHHHHH
HNFKASVMLTHAVLNFLKNRKRGRILYLLNEVYPDPILAGSRGALVPFAQSLSKQVAEHN
CCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCEECCCCCCHHHHHHHHHHHHHHCC
ITVNVLKLGLTEEFILAMHPEAKSIKEAVENLKVKEPHLRITEPEKITNTVTYLVSQFGA
CEEEEEEECCCHHHHEEECCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHCC
AVNGQVISLS
HHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]