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The map label for this gene is ctaC [H]

Identifier: 42521909

GI number: 42521909

Start: 271607

End: 272563

Strand: Direct

Name: ctaC [H]

Synonym: Bd0286

Alternate gene names: 42521909

Gene position: 271607-272563 (Clockwise)

Preceding gene: 42521908

Following gene: 42521910

Centisome position: 7.18

GC content: 47.02

Gene sequence:

>957_bases
ATGATGTGGTTTAATATTGCGAAGGCCCAATCCTTCATGCCCACGCAGGGAACCGAGATTGCGAAGCAGGTCGACAATCT
TTATGGATTCTTGCTTGTAACAAGTTTGATCGCCTGCGTCCTAGTGATCGGTGGGATGATCTATTTCGTTTGGAAATACA
GACGCAAGTCTTCCAACGACAAGACAGCCTATATCTCTCACAACACAGCGTTGGAGTTCTTGTGGTCATTCATTCCACTT
GTAATCTTCCTGGGTGTGTTCGGCTGGGGTTGGTACATCTATCACCAAATGCGCGCGATGCCTAAAAATGCGTTGGAAAT
CAACGTATTGGGTAAGCAGTGGGCTTGGGAAGTTGAATACAAGAACGGTTTCAAAACCGTGAATGAGGTTGTGGTACCAA
TCAATCAGGACGTGAAGATCCTTCTGACTTCCTCTGATGTGATCCACTCCTTCTTCGTTCCATCCTTCCGTATTAAACAG
GATGCGGTTCCAGGCCGTTACACAGCTTTGTGGTTCAAAGCTGACAAGCTGGGCGAATTCCACCTGTTCTGTACTGAGTA
CTGCGGTACTTCTCACTCCGGCATGATCGGTAAGTTGAGAGTTGTATCCCGTGAAGACTTCGACAAATACCTGGAACAGG
GTCAGGAAGAAAGATTCCTGCCACTGGGTGAAAAAGGTAAGAAATTGTTTGCGGTTAAAGCCTGCGCGTCCTGCCACGCA
GTGGACAGCCCTGCAACAATGGTCGGTCCTTCTTTGTTCCAAAAATTTGGTCACGAAGAAGTTATGGATGATGGTTCCAA
GATCGTATTCGACGAAAACTACATTCGCGAATCCATCCTTGAGCCCAACAAACACATCGTTAAAGGCTTCCCTAAGGGCG
TTATGCCCACCTTCCAGGGTCAGCTGAACGAAAACGAATTGAGTGCTCTTGTCGAGTACATCAAGAATCTGAAGTAA

Upstream 100 bases:

>100_bases
GGGCGGAGCGGTGATGGTTTTGGTGATGGTAATTTGGTTATTGCCTGTATGGATTCGCGCTCGCAGAGAGCAGAACAATA
CGGCGGGGAGATAAAGGTAC

Downstream 100 bases:

>100_bases
GGAGTTGAGCATGGCGAAAACTACAGCTCACGGCGACAACTATATTAATTTTGAAAAAGGCATCTGGTCCTGGCTGACTA
CTGTCGATCACAAACGTATC

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MMWFNIAKAQSFMPTQGTEIAKQVDNLYGFLLVTSLIACVLVIGGMIYFVWKYRRKSSNDKTAYISHNTALEFLWSFIPL
VIFLGVFGWGWYIYHQMRAMPKNALEINVLGKQWAWEVEYKNGFKTVNEVVVPINQDVKILLTSSDVIHSFFVPSFRIKQ
DAVPGRYTALWFKADKLGEFHLFCTEYCGTSHSGMIGKLRVVSREDFDKYLEQGQEERFLPLGEKGKKLFAVKACASCHA
VDSPATMVGPSLFQKFGHEEVMDDGSKIVFDENYIRESILEPNKHIVKGFPKGVMPTFQGQLNENELSALVEYIKNLK

Sequences:

>Translated_318_residues
MMWFNIAKAQSFMPTQGTEIAKQVDNLYGFLLVTSLIACVLVIGGMIYFVWKYRRKSSNDKTAYISHNTALEFLWSFIPL
VIFLGVFGWGWYIYHQMRAMPKNALEINVLGKQWAWEVEYKNGFKTVNEVVVPINQDVKILLTSSDVIHSFFVPSFRIKQ
DAVPGRYTALWFKADKLGEFHLFCTEYCGTSHSGMIGKLRVVSREDFDKYLEQGQEERFLPLGEKGKKLFAVKACASCHA
VDSPATMVGPSLFQKFGHEEVMDDGSKIVFDENYIRESILEPNKHIVKGFPKGVMPTFQGQLNENELSALVEYIKNLK
>Mature_318_residues
MMWFNIAKAQSFMPTQGTEIAKQVDNLYGFLLVTSLIACVLVIGGMIYFVWKYRRKSSNDKTAYISHNTALEFLWSFIPL
VIFLGVFGWGWYIYHQMRAMPKNALEINVLGKQWAWEVEYKNGFKTVNEVVVPINQDVKILLTSSDVIHSFFVPSFRIKQ
DAVPGRYTALWFKADKLGEFHLFCTEYCGTSHSGMIGKLRVVSREDFDKYLEQGQEERFLPLGEKGKKLFAVKACASCHA
VDSPATMVGPSLFQKFGHEEVMDDGSKIVFDENYIRESILEPNKHIVKGFPKGVMPTFQGQLNENELSALVEYIKNLK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=166, Percent_Identity=27.710843373494, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1786635, Length=213, Percent_Identity=27.6995305164319, Blast_Score=79, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6226540, Length=218, Percent_Identity=26.605504587156, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 36362; Mature: 36362

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMWFNIAKAQSFMPTQGTEIAKQVDNLYGFLLVTSLIACVLVIGGMIYFVWKYRRKSSND
CCEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KTAYISHNTALEFLWSFIPLVIFLGVFGWGWYIYHQMRAMPKNALEINVLGKQWAWEVEY
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEC
KNGFKTVNEVVVPINQDVKILLTSSDVIHSFFVPSFRIKQDAVPGRYTALWFKADKLGEF
CCCHHHHHHEEEECCCCEEEEEECHHHHHHHHCCCCEECCCCCCCCEEEEEEECCCCCCE
HLFCTEYCGTSHSGMIGKLRVVSREDFDKYLEQGQEERFLPLGEKGKKLFAVKACASCHA
EEEHHHHCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHC
VDSPATMVGPSLFQKFGHEEVMDDGSKIVFDENYIRESILEPNKHIVKGFPKGVMPTFQG
CCCCHHHCCHHHHHHCCCHHHHCCCCEEEECHHHHHHHHCCCCHHHHHCCCCCCCCCCCC
QLNENELSALVEYIKNLK
CCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMWFNIAKAQSFMPTQGTEIAKQVDNLYGFLLVTSLIACVLVIGGMIYFVWKYRRKSSND
CCEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KTAYISHNTALEFLWSFIPLVIFLGVFGWGWYIYHQMRAMPKNALEINVLGKQWAWEVEY
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEC
KNGFKTVNEVVVPINQDVKILLTSSDVIHSFFVPSFRIKQDAVPGRYTALWFKADKLGEF
CCCHHHHHHEEEECCCCEEEEEECHHHHHHHHCCCCEECCCCCCCCEEEEEEECCCCCCE
HLFCTEYCGTSHSGMIGKLRVVSREDFDKYLEQGQEERFLPLGEKGKKLFAVKACASCHA
EEEHHHHCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHC
VDSPATMVGPSLFQKFGHEEVMDDGSKIVFDENYIRESILEPNKHIVKGFPKGVMPTFQG
CCCCHHHCCHHHHHHCCCHHHHCCCCEEEECHHHHHHHHCCCCHHHHHCCCCCCCCCCCC
QLNENELSALVEYIKNLK
CCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]