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The map label for this gene is 38637772

Identifier: 38637772

GI number: 38637772

Start: 101129

End: 102226

Strand: Direct

Name: 38637772

Synonym: PHG107

Alternate gene names: NA

Gene position: 101129-102226 (Clockwise)

Preceding gene: 38637771

Following gene: 38637773

Centisome position: 22.37

GC content: 42.81

Gene sequence:

>1098_bases
ATGGCTCTTGATATTTCAAATTTGCCACAAGAAGCCATCAGCGCACTAAAGCAATTTCCAGAGTTTGAGATCGCTTCATT
CAACGACTCTGGAGCGAACGGATATGTACTTATTGGCCGGCATAGCGTGCTCCAAAAGGAAGTTGCTATAAAGATATATT
TCCACGGGGAGAGTGATATTGATCAAGAGCCAACGATTATTGCAAAGATAAATCACGAAAATGTCCTGAAAGTATACGAC
GCAAGAAAAGTGGGAAAAGATTGCTCATATTTCATGACGCCAGCGGCCAGTGAAGGTGATCTCGCAAATTTCCTAGATAC
GTATTTTATTTCACTTCCTCTGGCTCATAAGCTGCTATGCCAACTTTTATCTGGAATTGCGGCATTGCATATGAGTCCGA
ATTTGCTTGTGCATCGGGATTTGAAGCCCGAAAATCTGTTGGTTCATAACGACAATCTCTTGATTGCTGATTTTGGTTCA
GTTCGGCGAATCGATGAGAAAACGGGTAGTGCACCGGCATCGAAGCACAGCATTTTGTATAGACCGCCTGAAGCTTTTGG
TGAGGACTCATTCTTTAATTTTTCCTCAGATATCTACCAAGCCGGACTTATTGGATTTTTGTTATTTGGTGGGTCCTTGA
GCAATGATTTGCTTAGTTATTTGACAAAAAAACAAAAATCGGAGCTTACTGGTATTCAGGGTGGGTATGAGCTATCCATT
TATGTGGATTCTTGCATCGAAAAAAAAGTTTCACGCGGAAATTTGGCTGACTTTTCTACTCTTCCTTTTTACATTCCAGC
GGCCATTAAGCGCACATTGAGAGCAGCCATTTCTTCCGCCGACAAAAGATATTCCAGTGTCAGCGAATTTCTCGCAGAAT
TATCTCGATTAAGAGGAAATATGCCAGATTGGTCGACCCGACGTGAGGGTGTTCTGCTTCGCAATTGGAATGGACTAGAC
TACCGAATTCCGCACGACGAAGTCGCTATATTGAAGTGCAAATCAGGAGCCGAAAAGTATCGCTACGACAAAAGTTATAA
TTGTGGCAGCTATGCTGAGCTATTCGATCAAATGAAGGAGCGACTCGGGCTGCCATGA

Upstream 100 bases:

>100_bases
GGCGACTGAGCGGAGGGAGAATGGACGTAAAACTAACCGCCCCGCTACGGCAGATATTGGTAAGGCGTATGACCTGGCTT
ACGAGGGGTTGAATTGATCC

Downstream 100 bases:

>100_bases
CCTATTTATGGCACACGCCGGCCCTCGACCTCGATCTGACCGACGCCCCGCTGCAGGCCGACTTGGCCGAGTTGCGCGCG
CGTTTTCCTGAGACCCGCAC

Product: putative kinase

Products: NA

Alternate protein names: Serine/Threonine Protein Kinase; Serine/Threonine-Protein Kinase PksC

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MALDISNLPQEAISALKQFPEFEIASFNDSGANGYVLIGRHSVLQKEVAIKIYFHGESDIDQEPTIIAKINHENVLKVYD
ARKVGKDCSYFMTPAASEGDLANFLDTYFISLPLAHKLLCQLLSGIAALHMSPNLLVHRDLKPENLLVHNDNLLIADFGS
VRRIDEKTGSAPASKHSILYRPPEAFGEDSFFNFSSDIYQAGLIGFLLFGGSLSNDLLSYLTKKQKSELTGIQGGYELSI
YVDSCIEKKVSRGNLADFSTLPFYIPAAIKRTLRAAISSADKRYSSVSEFLAELSRLRGNMPDWSTRREGVLLRNWNGLD
YRIPHDEVAILKCKSGAEKYRYDKSYNCGSYAELFDQMKERLGLP

Sequences:

>Translated_365_residues
MALDISNLPQEAISALKQFPEFEIASFNDSGANGYVLIGRHSVLQKEVAIKIYFHGESDIDQEPTIIAKINHENVLKVYD
ARKVGKDCSYFMTPAASEGDLANFLDTYFISLPLAHKLLCQLLSGIAALHMSPNLLVHRDLKPENLLVHNDNLLIADFGS
VRRIDEKTGSAPASKHSILYRPPEAFGEDSFFNFSSDIYQAGLIGFLLFGGSLSNDLLSYLTKKQKSELTGIQGGYELSI
YVDSCIEKKVSRGNLADFSTLPFYIPAAIKRTLRAAISSADKRYSSVSEFLAELSRLRGNMPDWSTRREGVLLRNWNGLD
YRIPHDEVAILKCKSGAEKYRYDKSYNCGSYAELFDQMKERLGLP
>Mature_364_residues
ALDISNLPQEAISALKQFPEFEIASFNDSGANGYVLIGRHSVLQKEVAIKIYFHGESDIDQEPTIIAKINHENVLKVYDA
RKVGKDCSYFMTPAASEGDLANFLDTYFISLPLAHKLLCQLLSGIAALHMSPNLLVHRDLKPENLLVHNDNLLIADFGSV
RRIDEKTGSAPASKHSILYRPPEAFGEDSFFNFSSDIYQAGLIGFLLFGGSLSNDLLSYLTKKQKSELTGIQGGYELSIY
VDSCIEKKVSRGNLADFSTLPFYIPAAIKRTLRAAISSADKRYSSVSEFLAELSRLRGNMPDWSTRREGVLLRNWNGLDY
RIPHDEVAILKCKSGAEKYRYDKSYNCGSYAELFDQMKERLGLP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI166295196, Length=195, Percent_Identity=30.2564102564103, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI166295194, Length=195, Percent_Identity=30.2564102564103, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI166295192, Length=195, Percent_Identity=30.2564102564103, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI38569460, Length=252, Percent_Identity=26.984126984127, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI116256471, Length=250, Percent_Identity=27.6, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI116089335, Length=208, Percent_Identity=32.6923076923077, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI254028237, Length=226, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI254028240, Length=226, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI24308326, Length=208, Percent_Identity=32.2115384615385, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI254028232, Length=226, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI86990441, Length=226, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI254028234, Length=226, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI193083125, Length=231, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI46852166, Length=231, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI193083127, Length=231, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI193083129, Length=231, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI16936528, Length=184, Percent_Identity=28.2608695652174, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI153791472, Length=226, Percent_Identity=27.4336283185841, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17552716, Length=176, Percent_Identity=30.6818181818182, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI133901970, Length=268, Percent_Identity=27.6119402985075, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI133901968, Length=268, Percent_Identity=27.6119402985075, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320715, Length=228, Percent_Identity=30.7017543859649, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319825, Length=203, Percent_Identity=30.0492610837438, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319751, Length=227, Percent_Identity=26.8722466960352, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI17137070, Length=209, Percent_Identity=30.1435406698565, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648518, Length=206, Percent_Identity=28.6407766990291, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17647993, Length=224, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20128911, Length=197, Percent_Identity=29.9492385786802, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI45550626, Length=208, Percent_Identity=31.7307692307692, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40801; Mature: 40670

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00108 PROTEIN_KINASE_ST ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDISNLPQEAISALKQFPEFEIASFNDSGANGYVLIGRHSVLQKEVAIKIYFHGESDI
CCCCCCCCCHHHHHHHHHCCCCEEECCCCCCCCCEEEECCHHHHCEEEEEEEEECCCCCC
DQEPTIIAKINHENVLKVYDARKVGKDCSYFMTPAASEGDLANFLDTYFISLPLAHKLLC
CCCCEEEEEECCCCEEEHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
QLLSGIAALHMSPNLLVHRDLKPENLLVHNDNLLIADFGSVRRIDEKTGSAPASKHSILY
HHHHHHHHHHCCCCEEEEECCCCCCEEEECCCEEEECCCCHHHHHHHCCCCCCCCCCEEE
RPPEAFGEDSFFNFSSDIYQAGLIGFLLFGGSLSNDLLSYLTKKQKSELTGIQGGYELSI
CCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
YVDSCIEKKVSRGNLADFSTLPFYIPAAIKRTLRAAISSADKRYSSVSEFLAELSRLRGN
EEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MPDWSTRREGVLLRNWNGLDYRIPHDEVAILKCKSGAEKYRYDKSYNCGSYAELFDQMKE
CCCCCCCCCCEEEECCCCCCEECCCCCEEEEEECCCCHHHCCCCCCCCCHHHHHHHHHHH
RLGLP
HHCCC
>Mature Secondary Structure 
ALDISNLPQEAISALKQFPEFEIASFNDSGANGYVLIGRHSVLQKEVAIKIYFHGESDI
CCCCCCCCHHHHHHHHHCCCCEEECCCCCCCCCEEEECCHHHHCEEEEEEEEECCCCCC
DQEPTIIAKINHENVLKVYDARKVGKDCSYFMTPAASEGDLANFLDTYFISLPLAHKLLC
CCCCEEEEEECCCCEEEHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
QLLSGIAALHMSPNLLVHRDLKPENLLVHNDNLLIADFGSVRRIDEKTGSAPASKHSILY
HHHHHHHHHHCCCCEEEEECCCCCCEEEECCCEEEECCCCHHHHHHHCCCCCCCCCCEEE
RPPEAFGEDSFFNFSSDIYQAGLIGFLLFGGSLSNDLLSYLTKKQKSELTGIQGGYELSI
CCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
YVDSCIEKKVSRGNLADFSTLPFYIPAAIKRTLRAAISSADKRYSSVSEFLAELSRLRGN
EEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MPDWSTRREGVLLRNWNGLDYRIPHDEVAILKCKSGAEKYRYDKSYNCGSYAELFDQMKE
CCCCCCCCCCEEEECCCCCCEECCCCCEEEEEECCCCHHHCCCCCCCCCHHHHHHHHHHH
RLGLP
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA