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The map label for this gene is hypB2 [H]

Identifier: 38637760

GI number: 38637760

Start: 85836

End: 86798

Strand: Direct

Name: hypB2 [H]

Synonym: PHG095

Alternate gene names: 38637760

Gene position: 85836-86798 (Clockwise)

Preceding gene: 38637759

Following gene: 38637761

Centisome position: 18.98

GC content: 66.04

Gene sequence:

>963_bases
ATGTGCACCAACTGTGGCTGCGCCGCCGGCGAAACCCGCATCGAAGGCCAGGAGCTGGAGCATGTCGACGAGCATGCGCA
TGCCGACGGCACCGTCCATGGCCACGCCCCCCATCATCACGGCGAGCACGATCACGACCACGGCCCTGCCTACCGTGCCG
TGCGCGGTACTGACCATCTGCATTACGGTCACGGACCCGCTGGTGCCCATGCCCCAGGCATGAGCCAGGCGCGCATGGTG
AAGATCGAGCAGGACATCCTGGGCAAGAACAACGCCTACGCGGCGCAGAACCGCCGCTGGTTCGACGAGCACGGCGTGTT
CGCGCTGAACTTCGTCTCGAGCCCCGGCTCCGGGAAGACCACCCTGCTGGTGCGCACCATCGAGGCGCTGAAGTCCACCT
CCAGGCTGGCCGTCATCGAAGGCGACCAGCAGACTTCCTTCGATGCCGAGCGCATCCGCGCCACCGGCGTGCAGGCGCTG
CAGATCAACACCGGCAAGGGCTGCCACCTGGATGCCCACATGGTGGGCCACGCGCTGGAGAAACTGCGGCCGGAGGACGA
GAGCGTGCTGCTGATCGAGAACGTGGGCAACCTGGTCTGCCCTTCGGCCTTCGACCTGGGCGAAGCCCACAAGGTGGTGA
TCCTTTCGGTCACCGAAGGGGAGGACAAGCCCCTGAAATATCCTGACATGTTCCGCGCCGCCAGCCTGATGCTGCTCAAC
AAGTGCGACCTGCTGCCGCACCTGTCCTTCGACGTGGAGAGGGCCATCGAGTATGCGAAGCGGGTGAATCCGGACCTGCA
CGTGATCCGGACCTCGTCCGCCACCGGTGAAGGCTTCGACGCATGGCTGACGTGGATTGCCGATGGCCTGGCCGGCCAGG
CCGCCAGGCGCAGCCAGAGCATGGAGCTACTGCGCAGCCGCATCGCCGGGCTGGAAGCGCAACTGGCGGCGCTCAAGGTG
TAG

Upstream 100 bases:

>100_bases
GGTGCAGCCCACTGGCGGCACGGAAATGCGCGTCATGGATCTGGAAGTGGCGTGACGGAAAGCGGAAGTCACGCGGAATA
GAAGACGAGGAGACAGGATC

Downstream 100 bases:

>100_bases
CGGCCATGCTGATGCCGCGCCGTCCTCGCAATCCGCGCACCGTCCGCATCCGCATCCGCGTGCGCGGCGTCGTGCAGGGC
GTGGGCTTCCGGCCCTTCGT

Product: HypB2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MCTNCGCAAGETRIEGQELEHVDEHAHADGTVHGHAPHHHGEHDHDHGPAYRAVRGTDHLHYGHGPAGAHAPGMSQARMV
KIEQDILGKNNAYAAQNRRWFDEHGVFALNFVSSPGSGKTTLLVRTIEALKSTSRLAVIEGDQQTSFDAERIRATGVQAL
QINTGKGCHLDAHMVGHALEKLRPEDESVLLIENVGNLVCPSAFDLGEAHKVVILSVTEGEDKPLKYPDMFRAASLMLLN
KCDLLPHLSFDVERAIEYAKRVNPDLHVIRTSSATGEGFDAWLTWIADGLAGQAARRSQSMELLRSRIAGLEAQLAALKV

Sequences:

>Translated_320_residues
MCTNCGCAAGETRIEGQELEHVDEHAHADGTVHGHAPHHHGEHDHDHGPAYRAVRGTDHLHYGHGPAGAHAPGMSQARMV
KIEQDILGKNNAYAAQNRRWFDEHGVFALNFVSSPGSGKTTLLVRTIEALKSTSRLAVIEGDQQTSFDAERIRATGVQAL
QINTGKGCHLDAHMVGHALEKLRPEDESVLLIENVGNLVCPSAFDLGEAHKVVILSVTEGEDKPLKYPDMFRAASLMLLN
KCDLLPHLSFDVERAIEYAKRVNPDLHVIRTSSATGEGFDAWLTWIADGLAGQAARRSQSMELLRSRIAGLEAQLAALKV
>Mature_320_residues
MCTNCGCAAGETRIEGQELEHVDEHAHADGTVHGHAPHHHGEHDHDHGPAYRAVRGTDHLHYGHGPAGAHAPGMSQARMV
KIEQDILGKNNAYAAQNRRWFDEHGVFALNFVSSPGSGKTTLLVRTIEALKSTSRLAVIEGDQQTSFDAERIRATGVQAL
QINTGKGCHLDAHMVGHALEKLRPEDESVLLIENVGNLVCPSAFDLGEAHKVVILSVTEGEDKPLKYPDMFRAASLMLLN
KCDLLPHLSFDVERAIEYAKRVNPDLHVIRTSSATGEGFDAWLTWIADGLAGQAARRSQSMELLRSRIAGLEAQLAALKV

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=287, Percent_Identity=55.4006968641115, Blast_Score=314, Evalue=5e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 34833; Mature: 34833

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCTNCGCAAGETRIEGQELEHVDEHAHADGTVHGHAPHHHGEHDHDHGPAYRAVRGTDHL
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCEEEECCCCCE
HYGHGPAGAHAPGMSQARMVKIEQDILGKNNAYAAQNRRWFDEHGVFALNFVSSPGSGKT
ECCCCCCCCCCCCCCCCEEEEEHHHHCCCCCCCCCCCCCCHHHCCEEEEEEECCCCCCCE
TLLVRTIEALKSTSRLAVIEGDQQTSFDAERIRATGVQALQINTGKGCHLDAHMVGHALE
EEHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHCCEEEEEEECCCCCEEHHHHHHHHHH
KLRPEDESVLLIENVGNLVCPSAFDLGEAHKVVILSVTEGEDKPLKYPDMFRAASLMLLN
HHCCCCCCEEEEECCCCEECCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHH
KCDLLPHLSFDVERAIEYAKRVNPDLHVIRTSSATGEGFDAWLTWIADGLAGQAARRSQS
HHCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MELLRSRIAGLEAQLAALKV
HHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MCTNCGCAAGETRIEGQELEHVDEHAHADGTVHGHAPHHHGEHDHDHGPAYRAVRGTDHL
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCEEEECCCCCE
HYGHGPAGAHAPGMSQARMVKIEQDILGKNNAYAAQNRRWFDEHGVFALNFVSSPGSGKT
ECCCCCCCCCCCCCCCCEEEEEHHHHCCCCCCCCCCCCCCHHHCCEEEEEEECCCCCCCE
TLLVRTIEALKSTSRLAVIEGDQQTSFDAERIRATGVQALQINTGKGCHLDAHMVGHALE
EEHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHCCEEEEEEECCCCCEEHHHHHHHHHH
KLRPEDESVLLIENVGNLVCPSAFDLGEAHKVVILSVTEGEDKPLKYPDMFRAASLMLLN
HHCCCCCCEEEEECCCCEECCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHH
KCDLLPHLSFDVERAIEYAKRVNPDLHVIRTSSATGEGFDAWLTWIADGLAGQAARRSQS
HHCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MELLRSRIAGLEAQLAALKV
HHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]