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The map label for this gene is hypA2 [H]

Identifier: 38637759

GI number: 38637759

Start: 85449

End: 85790

Strand: Direct

Name: hypA2 [H]

Synonym: PHG094

Alternate gene names: 38637759

Gene position: 85449-85790 (Clockwise)

Preceding gene: 38637758

Following gene: 38637760

Centisome position: 18.9

GC content: 66.96

Gene sequence:

>342_bases
ATGCATGAGATGTCGCTGGCCGTGGGTGTGCTGCAGATCGTCGAGGACGTGGCGCAGCGCGACGGTTTTTCCCGCGTAAC
GGCAGTACGGCTGGAGATCGGCCGGCTGTCCAGTATCGAGCCGGAAGCGCTGCGCTTCTGCTTCGAGGAGGTAGTGCGCG
GCAGTGTGGCTGACGGCGCGCGGCTGGAGATCGTGGACACCCCCGGTGCCGGCTGGTGCCTGCACTGCAGCGAGACGGTG
GCGATCGGAGCGCTGTACGATCCCTGCCCGCAGTGCGGCGGCTACCAGGTGCAGCCCACTGGCGGCACGGAAATGCGCGT
CATGGATCTGGAAGTGGCGTGA

Upstream 100 bases:

>100_bases
CGTCCAGCTGAAATGCAAAAAAGCATATCCCTCGAGCGCCAGCGACGTGCGTCCCGTCGAGTGGTACCTCAGCGCGTGAC
CGACATGGTAGGAGCCGATC

Downstream 100 bases:

>100_bases
CGGAAAGCGGAAGTCACGCGGAATAGAAGACGAGGAGACAGGATCATGTGCACCAACTGTGGCTGCGCCGCCGGCGAAAC
CCGCATCGAAGGCCAGGAGC

Product: HypA2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHEMSLAVGVLQIVEDVAQRDGFSRVTAVRLEIGRLSSIEPEALRFCFEEVVRGSVADGARLEIVDTPGAGWCLHCSETV
AIGALYDPCPQCGGYQVQPTGGTEMRVMDLEVA

Sequences:

>Translated_113_residues
MHEMSLAVGVLQIVEDVAQRDGFSRVTAVRLEIGRLSSIEPEALRFCFEEVVRGSVADGARLEIVDTPGAGWCLHCSETV
AIGALYDPCPQCGGYQVQPTGGTEMRVMDLEVA
>Mature_113_residues
MHEMSLAVGVLQIVEDVAQRDGFSRVTAVRLEIGRLSSIEPEALRFCFEEVVRGSVADGARLEIVDTPGAGWCLHCSETV
AIGALYDPCPQCGGYQVQPTGGTEMRVMDLEVA

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789365, Length=112, Percent_Identity=41.9642857142857, Blast_Score=88, Evalue=1e-19,
Organism=Escherichia coli, GI1789081, Length=113, Percent_Identity=35.3982300884956, Blast_Score=78, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 12169; Mature: 12169

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMSLAVGVLQIVEDVAQRDGFSRVTAVRLEIGRLSSIEPEALRFCFEEVVRGSVADGA
CCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCC
RLEIVDTPGAGWCLHCSETVAIGALYDPCPQCGGYQVQPTGGTEMRVMDLEVA
EEEEEECCCCCEEEECCCEEEECCCCCCCCCCCCEEEECCCCCEEEEEEEEEC
>Mature Secondary Structure
MHEMSLAVGVLQIVEDVAQRDGFSRVTAVRLEIGRLSSIEPEALRFCFEEVVRGSVADGA
CCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCC
RLEIVDTPGAGWCLHCSETVAIGALYDPCPQCGGYQVQPTGGTEMRVMDLEVA
EEEEEECCCCCEEEECCCEEEECCCCCCCCCCCCEEEECCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA