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The map label for this gene is trkH [H]

Identifier: 37681413

GI number: 37681413

Start: 3319767

End: 3321212

Strand: Direct

Name: trkH [H]

Synonym: VV3229

Alternate gene names: 37681413

Gene position: 3319767-3321212 (Clockwise)

Preceding gene: 37681412

Following gene: 37681416

Centisome position: 98.96

GC content: 51.11

Gene sequence:

>1446_bases
ATGGTGAACTTTCGTCCCGTACTGTTTGTGATTGGGCTAGTGCTTTCTAAGCTCGCTCTTTTCATGTACGTCCCTACTCT
TGTGGCCTTTTTTACTGGCACAGGCGGCTTTCTTGATTTCGGCCAAGCGGTGTTGATCACCCATTTTGCCGCGTTTATCT
GCCTGAGTATTGGCCGCACCGCACACTTTAAACTCAGTGTGCGTGATATGTTCCTCATCACCAGTTTGGTGTGGACCATC
GCCAGCGCGTTTGCCGCGCTACCGTTTATGTTCATCAACCACATCAGCTTTACTGACGCCTACTTCGAAACCATGTCTGG
CATCACCACCACCGGTTCCACCGTGCTGAGTGGTTTGGATAACATGGCTCCGAGTATTTTGCTGTGGCGTTCGATCTTGC
AATGGCTTGGAGGAATTGGCTTTATTGTGATGGCCGTTGCGGTGCTGCCGATGCTAAACGTCGGCGGGATGAAGCTGTTC
CAAACGGAATCTTCCGATTGGTCAGACAAAAGCAGCCCAAGAGCCAAAACTGTGGCGAAAAACATTGTGGTGGTGTACCT
GGTACTCACCGGGCTCTGTTTGATTGGTTACCTGCTGACCGGCATGAACCTGTTTGATGCCATCAACCATTCCTTCACCA
CGCTTTCAACGGGCGGCTACTCCACCTCTGACGGTTCCATGAACCATTTTTCTAACGGCGCACACTGGGTCGCCACCTTA
TTTATGTTCTTGGGTGGTTTGCCATTTTTGTTGTTTGTTTCTGCGATGCGCAAGCGCCGCCTTGATGCTTTAATCAAAGA
CGCTCAAGTACGCGGTTTTACCTACCTGTTTTTAGGCACCAGCTTGGTCATTTCGGCTTGGTTGGTGATTCGTGACGGTT
ATACCATTGCCGATGCACTGCGCGTGGCGATGTTTAACATTGTTTCTGTGGTGACGACGACGGGCTTCGGCCTAGAAGAT
TTCACCGCCTGGGGCGCACTCCCTACGACCTTATTTGCGTTCTTGATGATGGCTGGCGCGTGTTCAGGCTCCACTTCTGG
CGGTATTAAGATCTTCCGCTTCCAGATCGCCATGACGCTGCTGAATAAACAGATCATGAAACTGATTCACCCATCAGGCA
TTTTTGTCCAACGCTACAATCAACGACCAGTGAATGATGACATTGTGCGCTCTGTGGTGGCGTTTGGTTTAATGTTCTTC
ATTACCATCATCGCCATTGCGGGCGGCTTAAGCGCGATGGGGCTTGATCCCGTCACCAGCATTTCTGGCTCAATTACCGC
GGTGGCCAACGTCGGCCCAGGTATGGGCAGCATCATTGGGCCAACAGGTAACTTCGCTCCGCTGCCTGATGCCGCTAAGT
GGCTACTCAGTTTCGGCATGTTGATGGGACGCTTAGAAATTCTCACCTTATTGGTGCTGTTTTTTCCTGCTTTCTGGCGC
CGTTAA

Upstream 100 bases:

>100_bases
ACAAGATGATCACGTGGTGATGTTCTTGGTCGATAAGAAATACGTACCAGACGTCGAAGCCTTGTTCCAGCCGAGCCCAT
TCTTCCTCTAGGATTTTCCT

Downstream 100 bases:

>100_bases
GTTTTGTCGAAGCGGCAATTTCTACAGCCCCAAAACAAAGAACCCGGTTTAAACCGGGTTCACATAAAGATAAATCGCTA
GGAAGTGACACACACAACCA

Product: potassium uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MVNFRPVLFVIGLVLSKLALFMYVPTLVAFFTGTGGFLDFGQAVLITHFAAFICLSIGRTAHFKLSVRDMFLITSLVWTI
ASAFAALPFMFINHISFTDAYFETMSGITTTGSTVLSGLDNMAPSILLWRSILQWLGGIGFIVMAVAVLPMLNVGGMKLF
QTESSDWSDKSSPRAKTVAKNIVVVYLVLTGLCLIGYLLTGMNLFDAINHSFTTLSTGGYSTSDGSMNHFSNGAHWVATL
FMFLGGLPFLLFVSAMRKRRLDALIKDAQVRGFTYLFLGTSLVISAWLVIRDGYTIADALRVAMFNIVSVVTTTGFGLED
FTAWGALPTTLFAFLMMAGACSGSTSGGIKIFRFQIAMTLLNKQIMKLIHPSGIFVQRYNQRPVNDDIVRSVVAFGLMFF
ITIIAIAGGLSAMGLDPVTSISGSITAVANVGPGMGSIIGPTGNFAPLPDAAKWLLSFGMLMGRLEILTLLVLFFPAFWR
R

Sequences:

>Translated_481_residues
MVNFRPVLFVIGLVLSKLALFMYVPTLVAFFTGTGGFLDFGQAVLITHFAAFICLSIGRTAHFKLSVRDMFLITSLVWTI
ASAFAALPFMFINHISFTDAYFETMSGITTTGSTVLSGLDNMAPSILLWRSILQWLGGIGFIVMAVAVLPMLNVGGMKLF
QTESSDWSDKSSPRAKTVAKNIVVVYLVLTGLCLIGYLLTGMNLFDAINHSFTTLSTGGYSTSDGSMNHFSNGAHWVATL
FMFLGGLPFLLFVSAMRKRRLDALIKDAQVRGFTYLFLGTSLVISAWLVIRDGYTIADALRVAMFNIVSVVTTTGFGLED
FTAWGALPTTLFAFLMMAGACSGSTSGGIKIFRFQIAMTLLNKQIMKLIHPSGIFVQRYNQRPVNDDIVRSVVAFGLMFF
ITIIAIAGGLSAMGLDPVTSISGSITAVANVGPGMGSIIGPTGNFAPLPDAAKWLLSFGMLMGRLEILTLLVLFFPAFWR
R
>Mature_481_residues
MVNFRPVLFVIGLVLSKLALFMYVPTLVAFFTGTGGFLDFGQAVLITHFAAFICLSIGRTAHFKLSVRDMFLITSLVWTI
ASAFAALPFMFINHISFTDAYFETMSGITTTGSTVLSGLDNMAPSILLWRSILQWLGGIGFIVMAVAVLPMLNVGGMKLF
QTESSDWSDKSSPRAKTVAKNIVVVYLVLTGLCLIGYLLTGMNLFDAINHSFTTLSTGGYSTSDGSMNHFSNGAHWVATL
FMFLGGLPFLLFVSAMRKRRLDALIKDAQVRGFTYLFLGTSLVISAWLVIRDGYTIADALRVAMFNIVSVVTTTGFGLED
FTAWGALPTTLFAFLMMAGACSGSTSGGIKIFRFQIAMTLLNKQIMKLIHPSGIFVQRYNQRPVNDDIVRSVVAFGLMFF
ITIIAIAGGLSAMGLDPVTSISGSITAVANVGPGMGSIIGPTGNFAPLPDAAKWLLSFGMLMGRLEILTLLVLFFPAFWR
R

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=501, Percent_Identity=34.5309381237525, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1787626, Length=431, Percent_Identity=34.1067285382831, Blast_Score=228, Evalue=8e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52160; Mature: 52160

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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C
>Mature Secondary Structure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C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]