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The map label for this gene is pssA

Identifier: 37681356

GI number: 37681356

Start: 3255340

End: 3256680

Strand: Direct

Name: pssA

Synonym: VV3172

Alternate gene names: 37681356

Gene position: 3255340-3256680 (Clockwise)

Preceding gene: 37681355

Following gene: 37681357

Centisome position: 97.04

GC content: 44.52

Gene sequence:

>1341_bases
ATGATGGCTAGCAGGAATCCTTTTGCACAGCTACCCAGCATTGCTGTGGATGCTGATGCTCTGGAAGTTCTTCATACAGC
GAAAGACTTCAGGACTCGCTTGATAGATGCGATCGCAAAAGCGACCTCTCGTATCTGCCTAGTGGCTTTGTATCTCGAAG
ATGATGAGGCCGGGCGAGAAATACTGACAGCGCTATACGAAGCTAAGCAACGCAATCCGGGTTTAGATATCAGCGTATGC
GTTGATTGGCACCGAGCACAACGTGGCTTGATCGGTGCTGAAAAATCTGAAGGTAATGCAGCGCTTTACAAAGCGTTTGC
GAACAAATATCAACACAAAATCCCTGTTTACGGCATTCCAGTTCGCGGTAGGGAAGTCTTTGGTGTACTCCATCTAAAAG
GCTTTATTGTCGACGATACGGTGATTTACAGCGGAGCGAGCCTCAACAACGTCTACCTTCAGTACAGTGAGCGTTATCGC
TTTGATCGATACCACGTCATTCATAATGAATCTCTTGCAGACACCATGTTCAATTTCGTCCAGAACGAAATGATAGCGCA
CCCTGCCGTGAATGATTTGGCAAAAGAAGATCGCCCCGAAACCAAAGAAATTAAGACCGCAATTCGTCAATTTCGATCAG
CGTTAGCTCGCGCTAAGTATCGCTTTGAATCTCAAGAGGCTGCCGAACATCAATTTTCCATCACCCCCATGGTTGGCTTA
GGAAAGAGGCGTAATTTCCTCAATCAAAACATCGCTAAGTTGATTGATGCAGCTCAAAGTGAAATATTCATATGTACGCC
CTACTTCAACTTTCCTAAAGATATCGCGAAGGGCGTGAAACGTGCGTTAAAACGTGGCGTAAAGGTGACGATTGTTGTAG
GCGATAAGACAGCTAACGACTTTTACATCGCACCAGACAAAGAATTCAAGACGATTGGTGGTTTACCCTATTTATATGAG
CTGAACCTACGCAAGTTTGCTAAAGCTTATGAAGCTCAAATAGCAGCAAGAAACCTTTCTATTCGACTCTGGAAAGATGG
CGATAACAGCTTCCATCTTAAAGGCATTTGGGTTGATAAACGCTACATGCTGCTGACAGGAAACAATCTCAATCCTAGGG
CTTGGGCGTTGGATCTCGAAAATGGTTTGTTGATCCGAGATGACTTTGCGCAACTAACAGAACAGTTTGATTCTGAGGTC
GACAATATTCTCCAGCACACTCAGTTAATTTGTACATACAAACAACTTGAGAAAGTCGAAGAATATCCGGAAGTGGTTCA
GAAGTTAGTCCGAAAGATCACTCGCATTAAAGCCGATGGCGTACTAAAGAGAATTCTCTAG

Upstream 100 bases:

>100_bases
AAATCCGCTAAGAATTCGCGCTTTTCTGGTATTGGATTTAATAAATTTGGTAGAATCGGCAGCTTGCAATACTGCACATA
ACGAAGGTAATACACCCCAT

Downstream 100 bases:

>100_bases
CATTGACAGCACATTTAAAACACTACTTAAGCCCAACGACACGTTGGGCTTTTTTATATGTGGAACTCCCAGAATGACGG
CAAACTCCCGCGATATTTAA

Product: phosphatidylserine synthase

Products: NA

Alternate protein names: Phosphatidylserine synthase [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MMASRNPFAQLPSIAVDADALEVLHTAKDFRTRLIDAIAKATSRICLVALYLEDDEAGREILTALYEAKQRNPGLDISVC
VDWHRAQRGLIGAEKSEGNAALYKAFANKYQHKIPVYGIPVRGREVFGVLHLKGFIVDDTVIYSGASLNNVYLQYSERYR
FDRYHVIHNESLADTMFNFVQNEMIAHPAVNDLAKEDRPETKEIKTAIRQFRSALARAKYRFESQEAAEHQFSITPMVGL
GKRRNFLNQNIAKLIDAAQSEIFICTPYFNFPKDIAKGVKRALKRGVKVTIVVGDKTANDFYIAPDKEFKTIGGLPYLYE
LNLRKFAKAYEAQIAARNLSIRLWKDGDNSFHLKGIWVDKRYMLLTGNNLNPRAWALDLENGLLIRDDFAQLTEQFDSEV
DNILQHTQLICTYKQLEKVEEYPEVVQKLVRKITRIKADGVLKRIL

Sequences:

>Translated_446_residues
MMASRNPFAQLPSIAVDADALEVLHTAKDFRTRLIDAIAKATSRICLVALYLEDDEAGREILTALYEAKQRNPGLDISVC
VDWHRAQRGLIGAEKSEGNAALYKAFANKYQHKIPVYGIPVRGREVFGVLHLKGFIVDDTVIYSGASLNNVYLQYSERYR
FDRYHVIHNESLADTMFNFVQNEMIAHPAVNDLAKEDRPETKEIKTAIRQFRSALARAKYRFESQEAAEHQFSITPMVGL
GKRRNFLNQNIAKLIDAAQSEIFICTPYFNFPKDIAKGVKRALKRGVKVTIVVGDKTANDFYIAPDKEFKTIGGLPYLYE
LNLRKFAKAYEAQIAARNLSIRLWKDGDNSFHLKGIWVDKRYMLLTGNNLNPRAWALDLENGLLIRDDFAQLTEQFDSEV
DNILQHTQLICTYKQLEKVEEYPEVVQKLVRKITRIKADGVLKRIL
>Mature_446_residues
MMASRNPFAQLPSIAVDADALEVLHTAKDFRTRLIDAIAKATSRICLVALYLEDDEAGREILTALYEAKQRNPGLDISVC
VDWHRAQRGLIGAEKSEGNAALYKAFANKYQHKIPVYGIPVRGREVFGVLHLKGFIVDDTVIYSGASLNNVYLQYSERYR
FDRYHVIHNESLADTMFNFVQNEMIAHPAVNDLAKEDRPETKEIKTAIRQFRSALARAKYRFESQEAAEHQFSITPMVGL
GKRRNFLNQNIAKLIDAAQSEIFICTPYFNFPKDIAKGVKRALKRGVKVTIVVGDKTANDFYIAPDKEFKTIGGLPYLYE
LNLRKFAKAYEAQIAARNLSIRLWKDGDNSFHLKGIWVDKRYMLLTGNNLNPRAWALDLENGLLIRDDFAQLTEQFDSEV
DNILQHTQLICTYKQLEKVEEYPEVVQKLVRKITRIKADGVLKRIL

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI87082134, Length=417, Percent_Identity=49.8800959232614, Blast_Score=432, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI25143331, Length=465, Percent_Identity=24.0860215053763, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI28572961, Length=453, Percent_Identity=23.841059602649, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016270
- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: =2.7.8.8 [H]

Molecular weight: Translated: 50952; Mature: 50952

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMASRNPFAQLPSIAVDADALEVLHTAKDFRTRLIDAIAKATSRICLVALYLEDDEAGRE
CCCCCCCHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHH
ILTALYEAKQRNPGLDISVCVDWHRAQRGLIGAEKSEGNAALYKAFANKYQHKIPVYGIP
HHHHHHHHHHCCCCCEEEEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECC
VRGREVFGVLHLKGFIVDDTVIYSGASLNNVYLQYSERYRFDRYHVIHNESLADTMFNFV
CCCHHHEEEEEEEEEEEECEEEECCCCCCCEEEEECCCCCCCCEEEEECCHHHHHHHHHH
QNEMIAHPAVNDLAKEDRPETKEIKTAIRQFRSALARAKYRFESQEAAEHQFSITPMVGL
HHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEECCCCCC
GKRRNFLNQNIAKLIDAAQSEIFICTPYFNFPKDIAKGVKRALKRGVKVTIVVGDKTAND
CHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCC
FYIAPDKEFKTIGGLPYLYELNLRKFAKAYEAQIAARNLSIRLWKDGDNSFHLKGIWVDK
CEECCCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEEEECC
RYMLLTGNNLNPRAWALDLENGLLIRDDFAQLTEQFDSEVDNILQHTQLICTYKQLEKVE
EEEEEECCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYPEVVQKLVRKITRIKADGVLKRIL
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMASRNPFAQLPSIAVDADALEVLHTAKDFRTRLIDAIAKATSRICLVALYLEDDEAGRE
CCCCCCCHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHH
ILTALYEAKQRNPGLDISVCVDWHRAQRGLIGAEKSEGNAALYKAFANKYQHKIPVYGIP
HHHHHHHHHHCCCCCEEEEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECC
VRGREVFGVLHLKGFIVDDTVIYSGASLNNVYLQYSERYRFDRYHVIHNESLADTMFNFV
CCCHHHEEEEEEEEEEEECEEEECCCCCCCEEEEECCCCCCCCEEEEECCHHHHHHHHHH
QNEMIAHPAVNDLAKEDRPETKEIKTAIRQFRSALARAKYRFESQEAAEHQFSITPMVGL
HHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEECCCCCC
GKRRNFLNQNIAKLIDAAQSEIFICTPYFNFPKDIAKGVKRALKRGVKVTIVVGDKTAND
CHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCC
FYIAPDKEFKTIGGLPYLYELNLRKFAKAYEAQIAARNLSIRLWKDGDNSFHLKGIWVDK
CEECCCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEEEECC
RYMLLTGNNLNPRAWALDLENGLLIRDDFAQLTEQFDSEVDNILQHTQLICTYKQLEKVE
EEEEEECCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYPEVVQKLVRKITRIKADGVLKRIL
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]