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The map label for this gene is coaA [H]

Identifier: 37681352

GI number: 37681352

Start: 3251786

End: 3252709

Strand: Direct

Name: coaA [H]

Synonym: VV3168

Alternate gene names: 37681352

Gene position: 3251786-3252709 (Clockwise)

Preceding gene: 37681342

Following gene: 37681355

Centisome position: 96.94

GC content: 44.26

Gene sequence:

>924_bases
ATGAGCCCATTTTTGTCATTTAGTCGCGCGACTTGGTCTGAATTACGTAATTCAGTGCCAATGACGTTGTCTGAAGAAGA
CTTAAAAGCATTGCAAGGGATCAATGAAAATCTCACCATGCAAGAAGCCGTGGAAGTGTATCTCCCTCTTTCCCGATTAT
TGAATCTTTATGTGCAGGCGAGGCAGAGCCGCAATTCGGTGCTCCATCAGTTTTTGAATAATGATGAACATGCTCCTCCT
TTCGTCATCGGTATCGCAGGTAGTGTGGCTGTAGGTAAGAGCACCACCGCTCGGGTCTTATGTGCTCTACTCTCTCGCTG
GGAAAATCATCCCAAAGTCGAACTGGTCACCACTGATGGTTTTCTCTATCCAAAGAAAATGCTGAATCAACGCGGTATCA
TGCATAAGAAAGGCTTTCCAGAATCTTATGATATGAAGAAGCTGGTGCAGTTTGTCTCTGATGTCAAAGCAGGTAAACCG
GAGCTTGAGGTTCCTGTTTACTCGCATATTACTTACGACATTACGGAGGAAGTAAAGAGAGTAGATCGCCCCGATGTTTT
GATCATCGAAGGATTGAATGTGCTGCAAAGTGGCATGGACTATCCACACGATCCTCATCGTGTTTTTGTTTCTGATTTCC
TCGATTTCTCAATTTACGTTGATGCTGAAAGCAATACGATAGAACAATGGTATGTGGAGCGCTTTCTCAAGTTCCGTAAA
GGCGCGTTTACTCAACCTGGCTCGTACTTTAGTCACTATACTCAACTTAGCGAGCAGCAAGCCATCGAGAAAGCGCAACA
GATTTGGCGAGACATTAATGGCATTAATTTAACGGAAAACATTTTGCCAACCAAAGAGCGAGCTCAGCTGATTCTGCGCA
AGGGCCAAAATCACTTGGTTGAAGAGATTCTGCTACGTAAATAG

Upstream 100 bases:

>100_bases
CTCTTTTTTCAATGAGGATTCACTATTGTCATTTGCTTTCTGTTACTCATGATGTATTTTGCATTCTCTTTCACGATTCA
CATGGAAAGGAAGCGTTCAT

Downstream 100 bases:

>100_bases
AGACTCTGACTCAGCATACCATTCGATTTCGTTACTGATCGTTAGCTCGCAAAGAGATTTCACCACCCACAAATGTTTGA
ATCCCTTCCACGGTTTTTAG

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSPFLSFSRATWSELRNSVPMTLSEEDLKALQGINENLTMQEAVEVYLPLSRLLNLYVQARQSRNSVLHQFLNNDEHAPP
FVIGIAGSVAVGKSTTARVLCALLSRWENHPKVELVTTDGFLYPKKMLNQRGIMHKKGFPESYDMKKLVQFVSDVKAGKP
ELEVPVYSHITYDITEEVKRVDRPDVLIIEGLNVLQSGMDYPHDPHRVFVSDFLDFSIYVDAESNTIEQWYVERFLKFRK
GAFTQPGSYFSHYTQLSEQQAIEKAQQIWRDINGINLTENILPTKERAQLILRKGQNHLVEEILLRK

Sequences:

>Translated_307_residues
MSPFLSFSRATWSELRNSVPMTLSEEDLKALQGINENLTMQEAVEVYLPLSRLLNLYVQARQSRNSVLHQFLNNDEHAPP
FVIGIAGSVAVGKSTTARVLCALLSRWENHPKVELVTTDGFLYPKKMLNQRGIMHKKGFPESYDMKKLVQFVSDVKAGKP
ELEVPVYSHITYDITEEVKRVDRPDVLIIEGLNVLQSGMDYPHDPHRVFVSDFLDFSIYVDAESNTIEQWYVERFLKFRK
GAFTQPGSYFSHYTQLSEQQAIEKAQQIWRDINGINLTENILPTKERAQLILRKGQNHLVEEILLRK
>Mature_306_residues
SPFLSFSRATWSELRNSVPMTLSEEDLKALQGINENLTMQEAVEVYLPLSRLLNLYVQARQSRNSVLHQFLNNDEHAPPF
VIGIAGSVAVGKSTTARVLCALLSRWENHPKVELVTTDGFLYPKKMLNQRGIMHKKGFPESYDMKKLVQFVSDVKAGKPE
LEVPVYSHITYDITEEVKRVDRPDVLIIEGLNVLQSGMDYPHDPHRVFVSDFLDFSIYVDAESNTIEQWYVERFLKFRKG
AFTQPGSYFSHYTQLSEQQAIEKAQQIWRDINGINLTENILPTKERAQLILRKGQNHLVEEILLRK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=308, Percent_Identity=61.3636363636364, Blast_Score=410, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 35339; Mature: 35208

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPFLSFSRATWSELRNSVPMTLSEEDLKALQGINENLTMQEAVEVYLPLSRLLNLYVQA
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RQSRNSVLHQFLNNDEHAPPFVIGIAGSVAVGKSTTARVLCALLSRWENHPKVELVTTDG
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCC
FLYPKKMLNQRGIMHKKGFPESYDMKKLVQFVSDVKAGKPELEVPVYSHITYDITEEVKR
CCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHEEHHHHHHHHH
VDRPDVLIIEGLNVLQSGMDYPHDPHRVFVSDFLDFSIYVDAESNTIEQWYVERFLKFRK
CCCCCEEEECCHHHHHHCCCCCCCCHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHC
GAFTQPGSYFSHYTQLSEQQAIEKAQQIWRDINGINLTENILPTKERAQLILRKGQNHLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHCCHHHHH
EEILLRK
HHHHHCC
>Mature Secondary Structure 
SPFLSFSRATWSELRNSVPMTLSEEDLKALQGINENLTMQEAVEVYLPLSRLLNLYVQA
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RQSRNSVLHQFLNNDEHAPPFVIGIAGSVAVGKSTTARVLCALLSRWENHPKVELVTTDG
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCC
FLYPKKMLNQRGIMHKKGFPESYDMKKLVQFVSDVKAGKPELEVPVYSHITYDITEEVKR
CCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHEEHHHHHHHHH
VDRPDVLIIEGLNVLQSGMDYPHDPHRVFVSDFLDFSIYVDAESNTIEQWYVERFLKFRK
CCCCCEEEECCHHHHHHCCCCCCCCHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHC
GAFTQPGSYFSHYTQLSEQQAIEKAQQIWRDINGINLTENILPTKERAQLILRKGQNHLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHCCHHHHH
EEILLRK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA