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The map label for this gene is dipZ

Identifier: 37681304

GI number: 37681304

Start: 3200813

End: 3202609

Strand: Direct

Name: dipZ

Synonym: VV3120

Alternate gene names: 37681304

Gene position: 3200813-3202609 (Clockwise)

Preceding gene: 37681303

Following gene: 37681305

Centisome position: 95.42

GC content: 49.86

Gene sequence:

>1797_bases
ATGCGCGCATTATTGACTTTCTTTGTTGCTGGATTGCTTGTGCTTTCCTCACCCGCCATGGCGCTGTTTGGCAATAACCA
AAACAGCAGTTTTGCTTCTGGCTCGAATGATTTTGTGCCTGTTGATCAGGCTTTTCCTTTTAACTATTTCCAGCAAGATC
ACCGCATCACCCTAGACTGGCAAGTCAAAGAGGGTTACTACCTCTATCAACAGCGTCTTTCATTTAGCGCAGAAAACGTT
GTATTGGGTGACATTCAAATGGAAAACGGCCAGCCCTACCGTGATGAATTTTTTGGCGATGTGAATATTTATACCAACCC
ATTGTTCGTTAACATCCCAATGCAAGACTGGCAGCCGGGCGCAAAATTGATCGTACAATACCAAGGCTGTGCCAAAGCGG
GCTTTTGCTATCCACCTGAAACACGAGTGATCGATATTGCCTCGTTTACCAATGGTGACATGGCACCAGCAACAATGCCG
ACACAAACCGCCAGCCCTCTCGATACATCAACAGCGAACACATCAACGCCTCAACCTCTGACTCAGCAAGATCAGTTGGC
TTCGGGCTTAGCGGATAACTGGTGGACGCCACTGCTGTTTTTGGCACTGGGTGTTGGCTTGGCCTTTACCCCTTGCGTAT
TGCCGATGTACCCGATTCTGACCAGCATCGTATTAGGCAGCGGTAAACTGAGTCAGCGACGCGCGCTTGGCCTCTCTCTT
GTCTATGTTCAAGGCATGGCACTGACCTATACCTTACTGGGTCTGGTTGTTGCTTCCGCTGGCTTGCAATTCCAAGCCGC
CATGCAGCACCCTTATGTGTTGATCGGCCTGAGTATTCTTTTTGTCACCTTAGCGCTCTCGATGTTTGGGGTGTACACCT
TACAACTGCCTAGCAGCGTACAAACTTGGCTGAACAATTTGAGCAATAAGCAGCAAGGTGGCAGTAGTACGGGTGTTTTT
GCCATGGGGGCCATTTCCGGTTTGGTGTGCTCGCCTTGTACCACAGCACCGCTTTCTGGGGCACTGCTGTACGTAGCACA
AAGTGGTGATCTCTTAACGGGGGGCGTTGCGCTGTATGCCTTAGCCATGGGCATGGGTATCCCTTTGATTTTAGTCGCGG
TGTTTGGCAATAAACTGCTCCCCAAAGCGGGCGGTTGGATGGATCACGTTAAAACGCTGTTTGGTTTTGTATTGCTGGCA
GCGCCAATCTTCCTATTGGAACGCATCCTTCCTGAAATGTGGTCAACCGCGCTGTGGTCTGCCTTGGGTATCGCGGCGTT
TGGCTGGCTTTACCATGTGAAAAATAGTTTGGAGTTTGGTGGTTGGAAGCAAAGCGCGGTGGGCATCATTGCTGTGCTGG
GTCTGTTTGCGTCCGCTCAGCCTGCCCTCAATTATTGGTTTGCTGACAGCTCTCAACAGGCTCAAACCAGCGAAGTGAGC
TTTATTAAAATCCGCAACGTCGAAGAGCTTCAACAACAATTGGCGTTAGCCAAGCAAGCCAAAAAACCTGTAATGCTCGA
CTTTTATGCCGATTGGTGTGTGGCGTGTAAAGAGTTCGAGAAATACACTTTCCACGACCCAGCCGTGGCAGCTCAACTCA
AACAATTTGTGTTGCTTCAAGCCGACGTGACGCGTAACCAAGCACAGGACATTGAGCTGCTACAGGCCCAACAAGTGCTC
GGCCTACCAACGATCGATTTTTGGGATGCGCAAGGTAATCCGGTTTCAAACGCTCGACTCACTGGCTTTATGCAAGCGGC
GCCTTTCTTGGAGCATATTCAACGAATTTCCAACTAA

Upstream 100 bases:

>100_bases
AATTTTCTGCACATAACCTTCCTATCGCTGAAACTTTCTGCACCGTTTCTGGGTCTGATTGGGTTAGACTAACTCCATTC
ACTCCCATATTTTGTTCACT

Downstream 100 bases:

>100_bases
CCGATTCAAACGCCAGCAAACCTTGCTGGCGTTTTTTCTTACCACATTCTCACCTTCACAACGGAGGTATATGCAAACTC
TCTAATAAAAGTCGATTTAC

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MRALLTFFVAGLLVLSSPAMALFGNNQNSSFASGSNDFVPVDQAFPFNYFQQDHRITLDWQVKEGYYLYQQRLSFSAENV
VLGDIQMENGQPYRDEFFGDVNIYTNPLFVNIPMQDWQPGAKLIVQYQGCAKAGFCYPPETRVIDIASFTNGDMAPATMP
TQTASPLDTSTANTSTPQPLTQQDQLASGLADNWWTPLLFLALGVGLAFTPCVLPMYPILTSIVLGSGKLSQRRALGLSL
VYVQGMALTYTLLGLVVASAGLQFQAAMQHPYVLIGLSILFVTLALSMFGVYTLQLPSSVQTWLNNLSNKQQGGSSTGVF
AMGAISGLVCSPCTTAPLSGALLYVAQSGDLLTGGVALYALAMGMGIPLILVAVFGNKLLPKAGGWMDHVKTLFGFVLLA
APIFLLERILPEMWSTALWSALGIAAFGWLYHVKNSLEFGGWKQSAVGIIAVLGLFASAQPALNYWFADSSQQAQTSEVS
FIKIRNVEELQQQLALAKQAKKPVMLDFYADWCVACKEFEKYTFHDPAVAAQLKQFVLLQADVTRNQAQDIELLQAQQVL
GLPTIDFWDAQGNPVSNARLTGFMQAAPFLEHIQRISN

Sequences:

>Translated_598_residues
MRALLTFFVAGLLVLSSPAMALFGNNQNSSFASGSNDFVPVDQAFPFNYFQQDHRITLDWQVKEGYYLYQQRLSFSAENV
VLGDIQMENGQPYRDEFFGDVNIYTNPLFVNIPMQDWQPGAKLIVQYQGCAKAGFCYPPETRVIDIASFTNGDMAPATMP
TQTASPLDTSTANTSTPQPLTQQDQLASGLADNWWTPLLFLALGVGLAFTPCVLPMYPILTSIVLGSGKLSQRRALGLSL
VYVQGMALTYTLLGLVVASAGLQFQAAMQHPYVLIGLSILFVTLALSMFGVYTLQLPSSVQTWLNNLSNKQQGGSSTGVF
AMGAISGLVCSPCTTAPLSGALLYVAQSGDLLTGGVALYALAMGMGIPLILVAVFGNKLLPKAGGWMDHVKTLFGFVLLA
APIFLLERILPEMWSTALWSALGIAAFGWLYHVKNSLEFGGWKQSAVGIIAVLGLFASAQPALNYWFADSSQQAQTSEVS
FIKIRNVEELQQQLALAKQAKKPVMLDFYADWCVACKEFEKYTFHDPAVAAQLKQFVLLQADVTRNQAQDIELLQAQQVL
GLPTIDFWDAQGNPVSNARLTGFMQAAPFLEHIQRISN
>Mature_598_residues
MRALLTFFVAGLLVLSSPAMALFGNNQNSSFASGSNDFVPVDQAFPFNYFQQDHRITLDWQVKEGYYLYQQRLSFSAENV
VLGDIQMENGQPYRDEFFGDVNIYTNPLFVNIPMQDWQPGAKLIVQYQGCAKAGFCYPPETRVIDIASFTNGDMAPATMP
TQTASPLDTSTANTSTPQPLTQQDQLASGLADNWWTPLLFLALGVGLAFTPCVLPMYPILTSIVLGSGKLSQRRALGLSL
VYVQGMALTYTLLGLVVASAGLQFQAAMQHPYVLIGLSILFVTLALSMFGVYTLQLPSSVQTWLNNLSNKQQGGSSTGVF
AMGAISGLVCSPCTTAPLSGALLYVAQSGDLLTGGVALYALAMGMGIPLILVAVFGNKLLPKAGGWMDHVKTLFGFVLLA
APIFLLERILPEMWSTALWSALGIAAFGWLYHVKNSLEFGGWKQSAVGIIAVLGLFASAQPALNYWFADSSQQAQTSEVS
FIKIRNVEELQQQLALAKQAKKPVMLDFYADWCVACKEFEKYTFHDPAVAAQLKQFVLLQADVTRNQAQDIELLQAQQVL
GLPTIDFWDAQGNPVSNARLTGFMQAAPFLEHIQRISN

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

Organism=Escherichia coli, GI1790578, Length=567, Percent_Identity=52.5573192239859, Blast_Score=568, Evalue=1e-163,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBD_VIBVY (Q7MGV6)

Other databases:

- EMBL:   BA000037
- RefSeq:   NP_935913.1
- ProteinModelPortal:   Q7MGV6
- STRING:   Q7MGV6
- GeneID:   2625980
- GenomeReviews:   BA000037_GR
- KEGG:   vvy:VV3120
- NMPDR:   fig|196600.1.peg.3186
- eggNOG:   COG4232
- HOGENOM:   HBG640883
- OMA:   RNGHEIG
- ProtClustDB:   PRK00293
- BioCyc:   VVUL196600:VV3120-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00399
- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10
- PANTHER:   PTHR10438

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin; SSF52833 Thiordxn-like_fd

EC number: =1.8.1.8

Molecular weight: Translated: 65184; Mature: 65184

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00194 THIOREDOXIN_1; PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1ae872a4)-; HASH(0x1ab8ac78)-; HASH(0x1b885cd8)-; HASH(0x1b7cec00)-; HASH(0x1b84ace8)-; HASH(0x1b3b2a00)-; HASH(0x1b914ba0)-; HASH(0x1b7945f0)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALLTFFVAGLLVLSSPAMALFGNNQNSSFASGSNDFVPVDQAFPFNYFQQDHRITLDW
CHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEECCCCCCCHHHCCCCEEEEEE
QVKEGYYLYQQRLSFSAENVVLGDIQMENGQPYRDEFFGDVNIYTNPLFVNIPMQDWQPG
EECCCHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHCCCCEEEECCEEEECCHHCCCCC
AKLIVQYQGCAKAGFCYPPETRVIDIASFTNGDMAPATMPTQTASPLDTSTANTSTPQPL
CEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TQQDQLASGLADNWWTPLLFLALGVGLAFTPCVLPMYPILTSIVLGSGKLSQRRALGLSL
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCEEE
VYVQGMALTYTLLGLVVASAGLQFQAAMQHPYVLIGLSILFVTLALSMFGVYTLQLPSSV
EHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCHHH
QTWLNNLSNKQQGGSSTGVFAMGAISGLVCSPCTTAPLSGALLYVAQSGDLLTGGVALYA
HHHHHHHCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEHHHHHHH
LAMGMGIPLILVAVFGNKLLPKAGGWMDHVKTLFGFVLLAAPIFLLERILPEMWSTALWS
HHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGIAAFGWLYHVKNSLEFGGWKQSAVGIIAVLGLFASAQPALNYWFADSSQQAQTSEVS
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCHHCCEE
FIKIRNVEELQQQLALAKQAKKPVMLDFYADWCVACKEFEKYTFHDPAVAAQLKQFVLLQ
EEEECCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ADVTRNQAQDIELLQAQQVLGLPTIDFWDAQGNPVSNARLTGFMQAAPFLEHIQRISN
HHHCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MRALLTFFVAGLLVLSSPAMALFGNNQNSSFASGSNDFVPVDQAFPFNYFQQDHRITLDW
CHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEECCCCCCCHHHCCCCEEEEEE
QVKEGYYLYQQRLSFSAENVVLGDIQMENGQPYRDEFFGDVNIYTNPLFVNIPMQDWQPG
EECCCHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHCCCCEEEECCEEEECCHHCCCCC
AKLIVQYQGCAKAGFCYPPETRVIDIASFTNGDMAPATMPTQTASPLDTSTANTSTPQPL
CEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TQQDQLASGLADNWWTPLLFLALGVGLAFTPCVLPMYPILTSIVLGSGKLSQRRALGLSL
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCEEE
VYVQGMALTYTLLGLVVASAGLQFQAAMQHPYVLIGLSILFVTLALSMFGVYTLQLPSSV
EHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCHHH
QTWLNNLSNKQQGGSSTGVFAMGAISGLVCSPCTTAPLSGALLYVAQSGDLLTGGVALYA
HHHHHHHCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEHHHHHHH
LAMGMGIPLILVAVFGNKLLPKAGGWMDHVKTLFGFVLLAAPIFLLERILPEMWSTALWS
HHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGIAAFGWLYHVKNSLEFGGWKQSAVGIIAVLGLFASAQPALNYWFADSSQQAQTSEVS
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCHHCCEE
FIKIRNVEELQQQLALAKQAKKPVMLDFYADWCVACKEFEKYTFHDPAVAAQLKQFVLLQ
EEEECCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ADVTRNQAQDIELLQAQQVLGLPTIDFWDAQGNPVSNARLTGFMQAAPFLEHIQRISN
HHHCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA